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Volumn 35, Issue 11, 2011, Pages 1527-1529

Low-level Bcr-Abl mutations are very rare in chronic myeloid leukemia patients who are in major molecular response on first-line nilotinib

Author keywords

Bcr Abl; Chronic myeloid leukemia; Kinase domain mutations; Major molecular response; Nilotinib

Indexed keywords

NILOTINIB;

EID: 80053932948     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2011.05.029     Document Type: Article
Times cited : (6)

References (11)
  • 1
    • 33847191776 scopus 로고    scopus 로고
    • Mutations of the BCR-ABL-kinase domain occur in a minority of patients with stable complete cytogenetic response to imatinib
    • Sherbenou D.W., Wong M.J., Humayun A., McGreevey L.S., Harrell P., Yang R., et al. Mutations of the BCR-ABL-kinase domain occur in a minority of patients with stable complete cytogenetic response to imatinib. Leukemia 2007, 21:489-493.
    • (2007) Leukemia , vol.21 , pp. 489-493
    • Sherbenou, D.W.1    Wong, M.J.2    Humayun, A.3    McGreevey, L.S.4    Harrell, P.5    Yang, R.6
  • 2
    • 54349089682 scopus 로고    scopus 로고
    • Finding of kinase domain mutations in patients with chronic phase chronic myeloid leukemia responding to imatinib may identify those at high risk of disease progression
    • Khorashad J.S., de Lavallade H., Apperley J.F., Milojkovic D., Reid A.G., Bua M., et al. Finding of kinase domain mutations in patients with chronic phase chronic myeloid leukemia responding to imatinib may identify those at high risk of disease progression. J Clin Oncol 2008, 26:4806-4813.
    • (2008) J Clin Oncol , vol.26 , pp. 4806-4813
    • Khorashad, J.S.1    de Lavallade, H.2    Apperley, J.F.3    Milojkovic, D.4    Reid, A.G.5    Bua, M.6
  • 3
    • 24744443720 scopus 로고    scopus 로고
    • High-sensitivity detection of BCR-ABL kinase domain mutations in imatinib-naive patients: correlation with clonal cytogenetic evolution but not response to therapy
    • Willis S.G., Lange T., Demehri S., Otto S., Crossman L., Niederwieser D., et al. High-sensitivity detection of BCR-ABL kinase domain mutations in imatinib-naive patients: correlation with clonal cytogenetic evolution but not response to therapy. Blood 2005, 106:2128-2137.
    • (2005) Blood , vol.106 , pp. 2128-2137
    • Willis, S.G.1    Lange, T.2    Demehri, S.3    Otto, S.4    Crossman, L.5    Niederwieser, D.6
  • 4
    • 73949145209 scopus 로고    scopus 로고
    • Nilotinib for the frontline treatment of Ph(+) chronic myeloid leukemia
    • Rosti G., Palandri F., Castagnetti F., Breccia M., Levato L., Gugliotta G., et al. Nilotinib for the frontline treatment of Ph(+) chronic myeloid leukemia. Blood 2009, 114:4933-4938.
    • (2009) Blood , vol.114 , pp. 4933-4938
    • Rosti, G.1    Palandri, F.2    Castagnetti, F.3    Breccia, M.4    Levato, L.5    Gugliotta, G.6
  • 5
    • 75749090051 scopus 로고    scopus 로고
    • Nilotinib as front-line treatment for patients with chronic myeloid leukemia in early chronic phase
    • Cortes J.E., Jones D., O'Brien S., Jabbour E., Konopleva M., Ferrajoli A., et al. Nilotinib as front-line treatment for patients with chronic myeloid leukemia in early chronic phase. J Clin Oncol 2010, 28:392-397.
    • (2010) J Clin Oncol , vol.28 , pp. 392-397
    • Cortes, J.E.1    Jones, D.2    O'Brien, S.3    Jabbour, E.4    Konopleva, M.5    Ferrajoli, A.6
  • 7
    • 3042612211 scopus 로고    scopus 로고
    • Denaturing-HPLC-based assay for detection of ABL mutations in chronic myeloid leukemia patients resistant to Imatinib
    • Soverini S., Martinelli G., Amabile M., Poerio A., Bianchini M., Rosti G., et al. Denaturing-HPLC-based assay for detection of ABL mutations in chronic myeloid leukemia patients resistant to Imatinib. Clin Chem 2004, 50:1205-1213.
    • (2004) Clin Chem , vol.50 , pp. 1205-1213
    • Soverini, S.1    Martinelli, G.2    Amabile, M.3    Poerio, A.4    Bianchini, M.5    Rosti, G.6
  • 8
    • 33749325184 scopus 로고    scopus 로고
    • Comparison of imatinib mesylate, dasatinib (BMS-354825), and nilotinib (AMN107) in an N-ethyl-N-nitrosourea (ENU)-based mutagenesis screen: high efficacy of drug combinations
    • Bradeen H.A., Eide C.A., O'Hare T., Johnson K.J., Willis S.G., Lee F.Y., et al. Comparison of imatinib mesylate, dasatinib (BMS-354825), and nilotinib (AMN107) in an N-ethyl-N-nitrosourea (ENU)-based mutagenesis screen: high efficacy of drug combinations. Blood 2006, 108:2332-2338.
    • (2006) Blood , vol.108 , pp. 2332-2338
    • Bradeen, H.A.1    Eide, C.A.2    O'Hare, T.3    Johnson, K.J.4    Willis, S.G.5    Lee, F.Y.6
  • 9
    • 34247506325 scopus 로고    scopus 로고
    • Identification of BCR-ABL point mutations conferring resistance to the Abl kinase inhibitor AMN107 (nilotinib) by a random mutagenesis study
    • Ray A., Cowan-Jacob S.W., Manley P.W., Mestan J., Griffin J.D. Identification of BCR-ABL point mutations conferring resistance to the Abl kinase inhibitor AMN107 (nilotinib) by a random mutagenesis study. Blood 2007, 109:5011-5015.
    • (2007) Blood , vol.109 , pp. 5011-5015
    • Ray, A.1    Cowan-Jacob, S.W.2    Manley, P.W.3    Mestan, J.4    Griffin, J.D.5
  • 10
    • 33745069351 scopus 로고    scopus 로고
    • Bcr-Abl resistance screening predicts a limited spectrum of point mutations to be associated with clinical resistance to the Abl kinase inhibitor nilotinib (AMN107)
    • von Bubnoff N., Manley P.W., Mestan J., Sanger J., Peschel C., Duyster J. Bcr-Abl resistance screening predicts a limited spectrum of point mutations to be associated with clinical resistance to the Abl kinase inhibitor nilotinib (AMN107). Blood 2006, 108:1328-1333.
    • (2006) Blood , vol.108 , pp. 1328-1333
    • von Bubnoff, N.1    Manley, P.W.2    Mestan, J.3    Sanger, J.4    Peschel, C.5    Duyster, J.6
  • 11
    • 14944367962 scopus 로고    scopus 로고
    • Detection of BCR-ABL kinase mutations in CD34+ cells from chronic myelogenous leukemia patients in complete cytogenetic remission on imatinib mesylate treatment
    • Chu S., Xu H., Shah N.P., Snyder D.S., Forman S.J., Sawyers C.L., et al. Detection of BCR-ABL kinase mutations in CD34+ cells from chronic myelogenous leukemia patients in complete cytogenetic remission on imatinib mesylate treatment. Blood 2005, 105:2093-2098.
    • (2005) Blood , vol.105 , pp. 2093-2098
    • Chu, S.1    Xu, H.2    Shah, N.P.3    Snyder, D.S.4    Forman, S.J.5    Sawyers, C.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.