Treatment and complications of thalassemia major in Guangxi, Southern China

Pediatric Blood and Cancer

Volumn 57, Issue 7, 2011, Pages 1174-1178

  Yin, Xiao Lin ^a   Wu, Zhi Kui ^b   He, Yuan Yuan ^a   Zhou, Tian Hong ^a   Zhou, Ya Li ^a   Zhang, Xin Hua ^a  

^a The 303rd Hospital of PLA   (China)

^b INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Beta thalassemia major; Complication; Iron overload; Transfusion

Indexed keywords

DEFERASIROX; DEFERIPRONE; DEFEROXAMINE; FERRITIN; HEMOGLOBIN;

ADOLESCENT; ADULT; ARTICLE; BLOOD TRANSFUSION; BODY HEIGHT; BODY WEIGHT; CHELATION THERAPY; CHILD; CHILDHOOD DISEASE; CHINA; CONTROLLED STUDY; FEMALE; FERRITIN BLOOD LEVEL; GROUPS BY AGE; GROWTH RETARDATION; HEMOGLOBIN BLOOD LEVEL; HEPATOMEGALY; HUMAN; HYPOTHYROIDISM; INFANT; IRON CHELATION; IRON OVERLOAD; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SPLENOMEGALY; SURVIVAL RATE; THALASSEMIA MAJOR;

ADOLESCENT; BETA-THALASSEMIA; BLOOD TRANSFUSION; CHILD; CHILD, PRESCHOOL; CHINA; FEMALE; FERRITINS; GROWTH DISORDERS; HEPATOMEGALY; HUMANS; HYPOTHYROIDISM; INFANT; IRON CHELATING AGENTS; IRON OVERLOAD; MALE; SPLENOMEGALY; YOUNG ADULT;

EID: 80053923574     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.23101     Document Type: Article

References (30)

1. Weatherall DJ. Keynote address: The challenge of thalassemia for the developing countries. Ann NY Acad Sci 2005; 1054: 11-17.
2. Ko TM, Hsu PM, Chen CJ, et al. Incidence study of heterozygous beta-thalassemia in northern Taiwan. Taiwan Yi Xue Hui Za Zhi 1989; 88: 678-681.
3. Xu XM, Zhou YQ, Luo GX, et al. The prevalence and spectrum of alpha and beta thalassaemia in Guangdong Province: Implications for the future health burden and population screening. J Clin Pathol 2004; 57: 517-522.
4. Lau YL, Chan LC, Chan YY, et al. Prevalence and genotypes of alpha- and beta-thalassemia carriers in Hong Kong-Implications for population screening. N Engl J Med 1997; 336: 1298-1301.
5. Xiong F, Sun M, Zhang X, et al. Molecular epidemiological survey of haemoglobinopathies in the Guangxi Zhuang Autonomous Region of southern China. Clin Genet 2010; 78: 139-148.
6. Pan HF, Long GF, Li Q, et al. Current status of thalassemia in minority populations in Guangxi, China. Clin Genet 2007; 71: 419-426.
7. Yin XL, Zhang XH, Zhou TH, et al. Hemoglobin H disease in Guangxi province, Southern China: Clinical review of 357 patients. Acta Haematol 2010; 124: 86-91.
8. Li H, Ji CY, Zong XN, et al. Height and weight standardized growth charts for Chinese children and adolescents aged 0 to 18 years. Zhonghua Er Ke Za Zhi 2009; 47: 487-492.
9. Li CK, Luk CW, Ling SC, et al. Morbidity and mortality patterns of thalassaemia major patients in Hong Kong: Retrospective study. Hong Kong Med J 2002; 8: 255-260.
10. Cunningham MJ, Macklin EA, Neufeld EJ, et al. Complications of beta-thalassemia major in North America. Blood 2004; 104: 34-39.
11. Najafipour F, Aliasgarzadeh A, Aghamohamadzadeh N, et al. A cross-sectional study of metabolic and endocrine complications in beta-thalassemia major. Ann Saudi Med 2008; 28: 361-366.
12. Greenwalt TJ, Zelenski KR. Transfusion support for haemoglobinopathies. Clin Haematol 1984; 13: 151-165.
13. Reynolds L, McKee M. Matching supply and demand for blood in Guizhou province, China: An unresolved challenge. J Public Health (Oxf) 2010; 32: 103-109.
14. Ward A, Caro JJ, Green TC, et al. An international survey of patients with thalassemia major and their views about sustaining life-long desferrioxamine use. BMC Clin Pharmacol 2002; 2: 3.
15. Weatherall DJ. Thalassemia as a global health problem: Recent progress toward its control in the developing countries. Ann NY Acad Sci 2010; 1202: 17-23.
16. Thuret I, Pondarre C, Loundou A, et al. Complications and treatment of patients with beta-thalassemia in France: Results of the National Registry. Haematologica 2010; 95: 724-729.
17. Borgna-Pignatti C, Rugolotto S, De Stefano P, et al. Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine. Haematologica 2004; 89: 1187-1193.
18. Vogiatzi MG, Macklin EA, Trachtenberg FL, et al. Differences in the prevalence of growth, endocrine and vitamin D abnormalities among the various thalassaemia syndromes in North America. Br J Haematol 2009; 146: 546-556.
19. George A, Bhaduri A, Sen S, et al. Physical growth parameters in thalassemic children. Indian J Pediatr 1997; 64: 861-871.
20. Wu KH, Tsai FJ, Peng CT. Growth hormone (GH) deficiency in patients with beta-thalassemia major and the efficacy of recombinant GH treatment. Ann Hematol 2003; 82: 637-640.
21. Charafeddine K, Ismáeel H, Charafeddine M, et al. Survival and complications of beta-thalassemia in Lebanon. Acta Haematol 2008; 120: 112-116.
22. Borgna-Pignatti C, Cappellini MD, De Stefano P, et al. Survival and complications in thalassemia. Ann NY Acad Sci 2005; 1054: 40-47.
23. Liang X, Bi S, Yang W, et al. Evaluation of the impact of hepatitis B vaccination among children born during 1992-2005 in China. J Infect Dis 2009; 200: 39-47.
24. Fu Y, Xia W, Wang Y, et al. The seroprevalence of hepatitis C virus (HCV) among 559, 890 first-time volunteer blood donors in China reflects regional heterogeneity in HCV prevalence and changes in blood donor recruitment models. Transfusion 2010; 50: 1505-1511.
25. Lu J, Zhou Y, Lin X, et al. General epidemiological parameters of viral hepatitis A, B, C, and E in six regions of China: A cross-sectional study in 2007. PLoS ONE 2009; 4: e8467.
26. Adams V, Erwin K, Le PV. Public health works: Blood donation in urban China. Soc Sci Med 2009; 68: 410-418.
27. Kremastinos DT, Farmakis D, Aessopos A, et al. Beta-thalassemia cardiomyopathy: History, present considerations, and future perspectives. Circ Heart Fail 2010; 3: 451-458.
28. De Sanctis V, Eleftheriou A, Malaventura C. Prevalence of endocrine complications and short stature in patients with thalassaemia major: A multicenter study by the Thalassaemia International Federation (TIF). Pediatr Endocrinol Rev 2004; 2: 249-255.
29. Ghosh S, Bandyopadhyay SK, Bandyopadhyay R, et al. A study on endocrine dysfunction in thalassaemia. J Indian Med Assoc 2008; 106: 655-656;, 658-659.
30. Luo M., 2010. Declaring a war against thalassemia: Guangxi province programed to strengthen prevention and treatment of thalassemia. <> Accessed 2010-11-30.