Lung cancer in lung transplant recipients: Experience of a tertiary hospital and literature review

Lung Cancer

Volumn 74, Issue 2, 2011, Pages 280-283

  Raviv, Yael ^a,b   Shitrit, David ^c   Amital, Anat ^a,b   Fox, Benjamin ^a,b   Rosengarten, Dror ^a,b   Fruchter, Oren ^a,b   Bakal, Ilana ^a,b   Kramer, Mordechai R ^a,b  

^a RABIN MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c MEIR MEDICAL CENTER   (Israel)

Author keywords

Bronchoalveolar carcinoma; Bronchogenic carcinoma; Lung transplant; Lung transplant outcome; Non small cell lung cancer; Post transplant malignancy

Indexed keywords

ADULT; ADVANCED CANCER; ARTICLE; CANCER MORTALITY; CHRONIC OBSTRUCTIVE LUNG DISEASE; FEMALE; FIBROSING ALVEOLITIS; GRAFT RECIPIENT; HUMAN; INTERSTITIAL LUNG DISEASE; LUNG CANCER; LUNG TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE COMPLICATION; PREVALENCE; PRIORITY JOURNAL; SMOKING; TERTIARY HEALTH CARE; TREATMENT INDICATION;

AGED; BRONCHI; FEMALE; FOLLOW-UP STUDIES; HOSPITALS; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; INDUSTRY; LUNG NEOPLASMS; LUNG TRANSPLANTATION; MALE; MEDICAL RECORDS SYSTEMS, COMPUTERIZED; MIDDLE AGED; NEOPLASM STAGING; POSTOPERATIVE COMPLICATIONS; PREVALENCE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RISK FACTORS; SMOKING; SURVIVAL ANALYSIS;

EID: 80053649526     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2011.02.012     Document Type: Article

References (24)

1. Toronto Lung Transplant Group Unilateral lung transplantation for pulmonary fibrosis. N Engl J Med 1986, 314:1140-1145.
2. International Society for Heart and Lung Transplantation. Available from: [accessed 2009]. http://www.ishlt.org/registries/heartLungRegistry.asp.
3. Swinnen L.J., Costanzo-Nordin M.R., Fisher S.G., O'Sullivan E.J., Johnson M.R., Heroux A.L., et al. Increased incidence of lymphoproliferative disorder after immunosuppression with the monoclonal antibody OKT3 in cardiac transplant recipients. N Engl J Med 1990, 323:1723-1728.
4. Penn I. Posttransplant malignancy: the role of immunosuppression. Drug Saf 2000, 23:101-113.
5. de Perrot M., Wigle D.A., Pierre A.F., Tsao M.S., Waddell T.K., Todd T.R., et al. Bronchogenic carcinoma after solid organ transplantation. Ann Thorac Surg 2003, 75:367-371.
6. Bouros D., Hatzakis K., Labrakis H., Zeibecoglou K. Association of malignancy with disease causing interstitial pulmonary changes. Chest 2002, 121:1278-1289.
7. Tockman M.S. Other host factors and lung cancer susceptibility. Epidemiology of lung cancer. Lung biology in health and disease 1994, vol. 74:397-412. Marcel Dekker, New York.
8. Peto R., Lopez A.D., Boreham J. Mortality from smoking in developed countries 1950-2000: indirect estimates from national vital statistics 1994, Oxford University Press, Oxford.
9. Detterbeck F.C., Boffa D.J., Tanoue L.T. The new lung cancer staging system. Chest 2009, 136:260-271.
10. Collins J., Kazerooni E.A., Lacomis J., McAdams H.P., Leung A.N., Shiau M., et al. Bronchogenic carcinoma after lung transplantation: frequency, clinical characteristics, and imaging finding. Radiology 2002, 224:131-138.
11. Dickson R.P., Davis R.D., Rea J.B., Palmer S.M. High frequency of bronchogenic carcinoma after single-lung transplantation. J Heart Lung Transplant 2006, 25:1297-1301.
12. Arcasoy S.M., Hersh C., Christie J.D., Zisman D., Pochettino A., Rosengard B.R., et al. Bronchogenic carcinoma complicating lung transplantation. J Heart Lung Transplant 2001, 20:1044-1053.
13. Spiekerkoetter E., Krug N., Hoeper M., Wiebe K., Hamm M., Harringer W., et al. Prevalence of malignancies after lung transplantation. Transplant Proc 1998, 30:1523-1524.
14. Choi Y.H., Leung A.N., Miro S., Poirier C., Hunt S., Theodore J. Primary bronchogenic carcinoma after heart or lung transplantation: radiologic and clinical findings. J Thorac Imaging 2000, 15:36-40.
15. Mathew J., Kratzke R.A. Lung cancer and lung transplantation: a review. J Thorac Oncol 2009, 4:753-760.
16. Minai O.A., Shah S., Mazzone P., Budev M.M., Sahoo D., Murthy S., et al. Bronchogenic carcinoma after lung transplantation: characteristics and outcome. J Thorac Oncol 2008, 3:1404-1409.
17. Abrahams N.A., Meziane M., Ramalingam P., Mehta A., DeCamp M., Farver C.F. Incidence of primary neoplasms in explanted lungs: long-term follow-up from 214 lung transplant patients. Transplant Proc 2004, 36:2808-2811.
18. de Perrot M., Fischer S., Waddell T.K., Strueber M., Harringer W., Pierre A.F., et al. Management of lung transplant recipients with bronchogenic carcinoma in the native lung. J Heart Lung Transplant 2003, 22:87-89.
19. de Perrot M., Chernanako S., Waddell T.K., Shargall Y., Pierre A.F., Hutcheon M., et al. Role of lung transplantation in the treatment of bronchogenic carcinomas for patients with end-stage pulmonary disease. J Clin Oncol 2004, 22:4351-4356.
20. Travis W.D., Travis L.B., Devesa S.S. Lung cancer. Cancer 1995, 75(Suppl.):191-202.
21. Greco R.J., Steiner R.M., Goldman S., Cotler H., Patchefsky A., Cohn H.E. Bronchioalveolar cell carcinoma of the lung. Ann Thorac Surg 1986, 41:652-656.
22. Okubo K., Mark E.J., Flieder D., Wain J.C., Wright C.D., Moncure A.C., et al. Bronchioalveolar carcinoma: clinical, radiographic, and pathologic factors and survival. J Thorac Cardiovasc Surg 1999, 118:702-709.
23. McMahon P.M., Kong C.Y., Johnson B.E., Weinstein M.C., Weeks J.C., Kuntz K.M., et al. Estimating long-term effectiveness of lung cancer screening in the Mayo CT screening study. Radiology 2008, 248:278-287.
24. Gutierrez-Dalmau A., Campistol J.M. Immunosuppressive therapy and malignancy in organ transplant recipients: a systematic review. Drugs 2007, 67:1167-1188.