The F279Y polymorphism of the GHR gene and its relation to milk production and somatic cell score in German Holstein dairy cattle

Journal of Applied Genetics

Volumn 52, Issue 4, 2011, Pages 459-465

  Rahmatalla, Siham A ^a   Müller, Uwe ^a   Strucken, Eva M ^a   Reissmann, Monika ^a   Brockmann, Gudrun A ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Cattle; Dairy breed; GHR gene; Milk traits; Single nucleotide polymorphism; Somatic cell score

Indexed keywords

FAT; GROWTH HORMONE RECEPTOR; LACTOSE; MILK PROTEIN;

ANIMAL; ARTICLE; CATTLE; CELL COUNT; CYTOLOGY; FEMALE; GENE FREQUENCY; GENETICS; GENOTYPE; GERMANY; LACTATION; METABOLISM; MILK; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; CATTLE; CELL COUNT; DNA MUTATIONAL ANALYSIS; FATS; FEMALE; GENE FREQUENCY; GENOTYPE; GERMANY; LACTATION; LACTOSE; MILK; MILK PROTEINS; MUTATION, MISSENSE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; RECEPTORS, SOMATOTROPIN;

BOS; BOVINAE;

EID: 80053648989     PISSN: 12341983     EISSN: None     Source Type: Journal    
DOI: 10.1007/s13353-011-0051-3     Document Type: Article

References (22)

1. Ali TE, Schaeffer LR (1987) Accounting for covariances among test day milk yields in dairy cows. Can J Anim Sci 67: 637-644.
2. Arranz JJ, Coppieters W, Berzi P, Cambisano N, Grisart B, Karim L, Marcq F, Moreau L, Mezer C, Riquet J, Simon P, Vanmanshoven P, Wagenaar D, Georges M (1998) A QTL affecting milk yield and composition maps to bovine chromosome 20: a confirmation. Anim Genet 29: 107-115.
3. Ashwell MS, van Tassell CP, Sonstegard TS (2001) A genome scan to identify quantitative trait loci affecting economically important traits in a US Holstein population. J Dairy Sci 84: 2535-2542.
4. Ashwell MS, Heyen DW, Sonstegard TS, van Tassell CP, Da Y, VanRaden PM, Ron M, Weller JI, Lewin HA (2004) Detection of quantitative trait loci affecting milk production, health, and reproductive traits in Holstein cattle. J Dairy Sci 87: 468-475.
5. Blott S, Kim JJ, Moisio S, Schmidt-Küntzel A, Cornet A, Berzi P, Cambisano N, Ford C, Grisart B, Johnson D, Karim L, Simon P, Snell R, Spelman R, Wong J, Vilkki J, Georges M, Farnir F, Coppieters W (2003) Molecular dissection of a quantitative trait locus: a phenylalanine-to-tyrosine substitution in the transmembrane domain of the bovine growth hormone receptor is associated with a major effect on milk yield and composition. Genetics 163: 253-266.
6. Casas E, Snowder GD (2008) A putative quantitative trait locus on chromosome 20 associated with bovine pathogenic disease incidence. J Anim Sci 86: 2455-2460.
7. Fontanesi L, Scotti E, Tazzoli M, Beretti F, Dall'Olio S, Davoli R, Russo V (2007) Investigation of allele frequencies of the growth hormone receptor (GHR) F279Y mutation in dairy and dual purpose cattle breeds. Ital J Anim Sci 6: 415-420.
8. Frank SJ, Gilliland G, Kraft AS, Arnold CS (1994) Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase. Endocrinology 135: 2228-2239.
9. Gengler N, Abras S, Verkenne C, Vanderick S, Szydlowski M, Renaville R (2008) Accuracy of prediction of gene content in large animal populations and its use for candidate gene detection and genetic evaluation. J Dairy Sci 91: 1652-1659.
10. Georges M, Nielsen D, Mackinnon M, Mishra A, Okimoto R, Pasquino AT, Sargeant LS, Sorensen A, Steele MR, Zhao X, Womack JE, Hoeschele I (1995) Mapping quantitative trait loci controlling milk production in dairy cattle by exploiting progeny testing. Genetics 139: 907-920.
11. Ji S, Frank SJ, Messina JL (2002) Growth hormone-induced differential desensitization of STAT5, ERK, and Akt phosphorylation. J Biol Chem 277: 28384-28393.
12. Kramer CY (1956) Extension of multiple range tests to group means with unequal numbers of replications. Biometrics 12: 307-310.
13. Lucy MC, Jiang H, Kobayashi Y (2001) Changes in the somatotrophic axis associated with the initiation of lactation. J Dairy Sci 84(E-Suppl): E113-E119.
14. Oikonomou G, Angelopoulou K, Arsenos G, Zygoyiannis D, Banos G (2009) The effects of polymorphisms in the DGAT1, leptin and growth hormone receptor gene loci on body energy, blood metabolic and reproductive traits of Holstein cows. Anim Genet 40: 10-17.
15. Parmentier I, Portetelle D, Gengler N, Prandi A, Bertozzi C, Vleurick L, Gilson R, Renaville R (1999) Candidate gene markers associated with somatotropic axis and milk selection. Domest Anim Endocrinol 17: 139-148.
16. Rodriguez-Zas SL, Southey BR, Heyen DW, Lewin HA (2002) Interval and composite interval mapping of somatic cell score, yield, and components of milk in dairy cattle. J Dairy Sci 85: 3081-3091.
17. Ron M, Feldmesser E, Golik M, Tager-Cohen I, Kliger D, Reiss V, Domochovsky R, Alus O, Seroussi E, Ezra E, Weller JI (2004) A complete genome scan of the Israeli Holstein population for quantitative trait loci by a daughter design. J Dairy Sci 87: 476-490.
18. Stoop WM, Bovenhuis H, van Arendonk JA (2007) Genetic parameters for milk urea nitrogen in relation to milk production traits. J Dairy Sci 90: 1981-1986.
19. Viitala SM, Schulman NF, de Koning DJ, Elo K, Kinos R, Virta A, Virta J, Mäki-Tanila A, Vilkki JH (2003) Quantitative trait loci affecting milk production traits in Finnish Ayrshire dairy cattle. J Dairy Sci 86: 1828-1836.
20. Viitala S, Szyda J, Blott S, Schulman N, Lidauer M, Mäki-Tanila A, Georges M, Vilkki J (2006) The role of the bovine growth hormone receptor and prolactin receptor genes in milk, fat and protein production in Finnish Ayrshire dairy cattle. Genetics 173: 2151-2164.
21. Waters SM, McCabe MS, Howard DJ, Giblin L, Magee DA, MacHugh DE, Berry DP (2011) Associations between newly discovered polymorphisms in the Bos taurus growth hormone receptor gene and performance traits in Holstein-Friesian dairy cattle. Anim Genet 42: 39-49.
22. Welper RD, Freeman AE (1992) Genetic parameters for yield traits of Holsteins, including lactose and somatic cell score. J Dairy Sci 75: 1342-1348.