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Volumn , Issue , 2009, Pages 235-260

Thiamine deficiency: A model of metabolic encephalopathy and of selective neuronal vulnerability

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EID: 80053647121     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-79112-8_12     Document Type: Chapter
Times cited : (5)

References (92)
  • 1
    • 0141748337 scopus 로고    scopus 로고
    • Wernicke's encephalopathy in AIDS: A preventable cause of fatal neurological deficit
    • Alcaide, M. L., et al., 2003. Wernicke's encephalopathy in AIDS: a preventable cause of fatal neurological deficit. Int J STD AIDS. 14, 712-713.
    • (2003) Int J STD AIDS. , vol.14 , pp. 712-713
    • Alcaide, M.L.1
  • 2
    • 33748078474 scopus 로고    scopus 로고
    • Beriberi after bariatric surgery: Not an unusual complication. Report of two cases and literature review
    • Alves, L. F., et al., 2006. [Beriberi after bariatric surgery: not an unusual complication. Report of two cases and literature review]. Arq Bras Endocrinol Metabol. 50, 564-568.
    • (2006) Arq Bras Endocrinol Metabol. , vol.50 , pp. 564-568
    • Alves, L.F.1
  • 3
    • 0034955984 scopus 로고    scopus 로고
    • Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease
    • Andreassen, O. A., et al., 2001. Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease. Ann Neurol. 50, 112-117.
    • (2001) Ann Neurol. , vol.50 , pp. 112-117
    • Andreassen, O.A.1
  • 4
    • 0013921481 scopus 로고
    • Tissue and intracellular distribution of radioactive thiamine in normal and thiamine-deficient rats
    • Balaghi, M., Pearson, W. N., 1966. Tissue and intracellular distribution of radioactive thiamine in normal and thiamine-deficient rats. J Nutr. 89, 127-132.
    • (1966) J Nutr. , vol.89 , pp. 127-132
    • Balaghi, M.1    Pearson, W.N.2
  • 5
    • 0020449443 scopus 로고
    • Spontaneous open-field behavior in thiamin-deficient rats
    • Barclay, L. L., Gibson, G. E., 1982. Spontaneous open-field behavior in thiamin-deficient rats. J Nutr. 112, 1899-1905.
    • (1982) J Nutr. , vol.112 , pp. 1899-1905
    • Barclay, L.L.1    Gibson, G.E.2
  • 6
    • 0019487836 scopus 로고
    • Impairment of behavior and acetylcholine metabolism in thiamine deficiency
    • Barclay, L. L., et al., 1981a. Impairment of behavior and acetylcholine metabolism in thiamine deficiency. J Pharmacol Exp Ther. 217, 537-543.
    • (1981) J Pharmacol Exp Ther. , vol.217 , pp. 537-543
    • Barclay, L.L.1
  • 7
    • 0019415083 scopus 로고
    • The string test: An early behavioral change in thiamine deficiency
    • Barclay, L. L., et al., 1981b. The string test: an early behavioral change in thiamine deficiency. Pharmacol Biochem Behav. 14, 153-157.
    • (1981) Pharmacol Biochem Behav. , vol.14 , pp. 153-157
    • Barclay, L.L.1
  • 8
    • 0020423244 scopus 로고
    • Cholinergic therapy of abnormal open-field behavior in thiamin-deficient rats
    • Barclay, L. L., et al., 1982. Cholinergic therapy of abnormal open-field behavior in thiamin-deficient rats. J Nutr. 112, 1906-1913.
    • (1982) J Nutr. , vol.112 , pp. 1906-1913
    • Barclay, L.L.1
  • 9
    • 0017571187 scopus 로고
    • Abnormality of a thiamine-requiring enzyme in patients with Wernicke-Korsakoff syndrome
    • Blass, J. P., Gibson, G. E., 1977. Abnormality of a thiamine-requiring enzyme in patients with Wernicke-Korsakoff syndrome. N Engl J Med. 297, 1367-1370.
    • (1977) N Engl J Med. , vol.297 , pp. 1367-1370
    • Blass, J.P.1    Gibson, G.E.2
  • 10
    • 0018763637 scopus 로고
    • Genetic factors in Wernicke-Korsakoff syndrome
    • Blass, J. P., Gibson, G. E., 1979. Genetic factors in Wernicke-Korsakoff syndrome. Alcohol Clin Exp Res. 3, 126-134.
    • (1979) Alcohol Clin Exp Res. , vol.3 , pp. 126-134
    • Blass, J.P.1    Gibson, G.E.2
  • 12
    • 18244390483 scopus 로고    scopus 로고
    • Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
    • Bubber, P., et al., 2005. Mitochondrial abnormalities in Alzheimer brain: mechanistic implications. Ann Neurol. 57, 695-703.
    • (2005) Ann Neurol. , vol.57 , pp. 695-703
    • Bubber, P.1
  • 13
    • 0023722279 scopus 로고
    • The pentose phosphate pathway in the endoplasmic reticulum
    • Bublitz, C., Steavenson, S., 1988. The pentose phosphate pathway in the endoplasmic reticulum. J Biol Chem. 263, 12849-12853.
    • (1988) J Biol Chem. , vol.263 , pp. 12849-12853
    • Bublitz, C.1    Steavenson, S.2
  • 14
    • 0027131501 scopus 로고
    • Thiamine-dependent enzyme changes in the brains of alcoholics: Relationship to the Wernicke-Korsakoff syndrome
    • Butterworth, R. F., et al., 1993. Thiamine-dependent enzyme changes in the brains of alcoholics: relationship to the Wernicke-Korsakoff syndrome. Alcohol Clin Exp Res. 17, 1084-1088.
    • (1993) Alcohol Clin Exp Res. , vol.17 , pp. 1084-1088
    • Butterworth, R.F.1
  • 15
    • 0034575582 scopus 로고    scopus 로고
    • Dietary restriction attenuates the neuronal loss, induction of heme oxygenase-1 and blood-brain barrier breakdown induced by impaired oxidative metabolism
    • Calingasan, N. Y., Gibson, G. E., 2000a. Dietary restriction attenuates the neuronal loss, induction of heme oxygenase-1 and blood-brain barrier breakdown induced by impaired oxidative metabolism. Brain Res. 885, 62-69.
    • (2000) Brain Res. , vol.885 , pp. 62-69
    • Calingasan, N.Y.1    Gibson, G.E.2
  • 16
    • 0034019969 scopus 로고    scopus 로고
    • Vascular endothelium is a site of free radical production and inflammation in areas of neuronal loss in thiamine-deficient brain
    • Calingasan, N. Y., Gibson, G. E., 2000b. Vascular endothelium is a site of free radical production and inflammation in areas of neuronal loss in thiamine-deficient brain. Ann N Y Acad Sci. 903, 353-356.
    • (2000) Ann N Y Acad Sci. , vol.903 , pp. 353-356
    • Calingasan, N.Y.1    Gibson, G.E.2
  • 17
    • 0028169899 scopus 로고
    • Distribution of the alpha-ketoglutarate dehydrogenase complex in rat brain
    • Calingasan, N. Y., et al., 1994a. Distribution of the alpha-ketoglutarate dehydrogenase complex in rat brain. J Comp Neurol. 346, 461-479.
    • (1994) J Comp Neurol. , vol.346 , pp. 461-479
    • Calingasan, N.Y.1
  • 18
    • 0028269903 scopus 로고
    • Selective enrichment of cholinergic neurons with the alphaketoglutarate dehydrogenase complex in rat brain
    • Calingasan, N. Y., et al., 1994b. Selective enrichment of cholinergic neurons with the alphaketoglutarate dehydrogenase complex in rat brain. Neurosci Lett. 168, 209-212.
    • (1994) Neurosci Lett. , vol.168 , pp. 209-212
    • Calingasan, N.Y.1
  • 19
    • 0029151132 scopus 로고
    • Blood-brain barrier abnormalities in vulnerable brain regions during thiamine deficiency
    • Calingasan, N. Y., et al., 1995a. Blood-brain barrier abnormalities in vulnerable brain regions during thiamine deficiency. Exp Neurol. 134, 64-72.
    • (1995) Exp Neurol. , vol.134 , pp. 64-72
    • Calingasan, N.Y.1
  • 20
    • 0028986273 scopus 로고
    • Accumulation of amyloid precursor protein-like immunoreactivity in rat brain in response to thiamine deficiency
    • Calingasan, N. Y., et al., 1995b. Accumulation of amyloid precursor protein-like immunoreactivity in rat brain in response to thiamine deficiency. Brain Res. 677, 50-60.
    • (1995) Brain Res. , vol.677 , pp. 50-60
    • Calingasan, N.Y.1
  • 21
    • 0028861710 scopus 로고
    • Heterogeneous expression of transketolase in rat brain
    • Calingasan, N. Y., et al., 1995c. Heterogeneous expression of transketolase in rat brain. J Neurochem. 64, 1034-1044.
    • (1995) J Neurochem. , vol.64 , pp. 1034-1044
    • Calingasan, N.Y.1
  • 22
    • 10144231437 scopus 로고    scopus 로고
    • Novel neuritic clusters with accumulations of amyloid precursor protein and amyloid precursor-like protein 2 immunoreactivity in brain regions damaged by thiamine deficiency
    • Calingasan, N. Y., et al., 1996. Novel neuritic clusters with accumulations of amyloid precursor protein and amyloid precursor-like protein 2 immunoreactivity in brain regions damaged by thiamine deficiency. Am J Pathol. 149, 1063-1071.
    • (1996) Am J Pathol. , vol.149 , pp. 1063-1071
    • Calingasan, N.Y.1
  • 23
    • 0031830710 scopus 로고    scopus 로고
    • Induction of nitric oxide synthase and microglial responses precede selective cell death induced by chronic impairment of oxidative metabolism
    • Calingasan, N. Y., et al., 1998. Induction of nitric oxide synthase and microglial responses precede selective cell death induced by chronic impairment of oxidative metabolism. Am J Pathol. 153, 599-610.
    • (1998) Am J Pathol. , vol.153 , pp. 599-610
    • Calingasan, N.Y.1
  • 24
    • 0032849357 scopus 로고    scopus 로고
    • Oxidative stress is associated with region-specific neuronal death during thiamine deficiency
    • Calingasan, N. Y., et al., 1999. Oxidative stress is associated with region-specific neuronal death during thiamine deficiency. J Neuropathol Exp Neurol. 58, 946-958.
    • (1999) J Neuropathol Exp Neurol. , vol.58 , pp. 946-958
    • Calingasan, N.Y.1
  • 25
    • 0034058593 scopus 로고    scopus 로고
    • Vascular factors are critical in selective neuronal loss in an animal model of impaired oxidative metabolism
    • Calingasan, N. Y., et al., 2000. Vascular factors are critical in selective neuronal loss in an animal model of impaired oxidative metabolism. J Neuropathol Exp Neurol. 59, 207-217.
    • (2000) J Neuropathol Exp Neurol. , vol.59 , pp. 207-217
    • Calingasan, N.Y.1
  • 26
    • 21244460340 scopus 로고    scopus 로고
    • Mutations in the transketolase-like gene TKTL1: Clinical implications for neurodegenerative diseases, diabetes and cancer
    • Coy, J. F., et al., 2005. Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer. Clin Lab. 51, 257-273.
    • (2005) Clin Lab. , vol.51 , pp. 257-273
    • Coy, J.F.1
  • 27
    • 24644507046 scopus 로고    scopus 로고
    • Role of mitochondrial dysfunction and oxidative stress in the pathogenesis of selective neuronal loss in Wernicke's encephalopathy
    • Desjardins, P., Butterworth, R. F., 2005. Role of mitochondrial dysfunction and oxidative stress in the pathogenesis of selective neuronal loss in Wernicke's encephalopathy. Mol Neurobiol. 31, 17-25.
    • (2005) Mol Neurobiol. , vol.31 , pp. 17-25
    • Desjardins, P.1    Butterworth, R.F.2
  • 28
    • 0017108579 scopus 로고
    • Ketonic diet in the management of pyruvate dehydrogenase deficiency
    • Falk, R. E., et al., 1976. Ketonic diet in the management of pyruvate dehydrogenase deficiency. Pediatrics. 58, 713-721.
    • (1976) Pediatrics. , vol.58 , pp. 713-721
    • Falk, R.E.1
  • 29
    • 34249942508 scopus 로고    scopus 로고
    • Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer
    • Foldi, M., et al., 2007. Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer. Oncol Rep. 17, 841-845.
    • (2007) Oncol Rep. , vol.17 , pp. 841-845
    • Foldi, M.1
  • 30
    • 0023406340 scopus 로고
    • Effect of age on behavioral and enzymatic changes during thiamin deficiency
    • Freeman, G. B., et al., 1987. Effect of age on behavioral and enzymatic changes during thiamin deficiency. Neurobiol Aging. 8, 429-434.
    • (1987) Neurobiol Aging. , vol.8 , pp. 429-434
    • Freeman, G.B.1
  • 31
    • 0017112552 scopus 로고
    • Impaired synthesis of acetylcholine in brain accompanying mild hypoxia and hypoglycemia
    • Gibson, G. E., Blass, J. P., 1976. Impaired synthesis of acetylcholine in brain accompanying mild hypoxia and hypoglycemia. J Neurochem. 27, 37-42.
    • (1976) J Neurochem. , vol.27 , pp. 37-42
    • Gibson, G.E.1    Blass, J.P.2
  • 32
    • 34648827549 scopus 로고    scopus 로고
    • Thiamine-dependent processes and treatment strategies in neurodegeneration
    • Gibson, G. E., Blass, J. P., 2007. Thiamine-dependent processes and treatment strategies in neurodegeneration. Antioxid Redox Signal. 9, 1605-1619.
    • (2007) Antioxid Redox Signal. , vol.9 , pp. 1605-1619
    • Gibson, G.E.1    Blass, J.P.2
  • 33
    • 0016741395 scopus 로고
    • Decreased synthesis of acetylcholine accompanying impaired oxidation of pyruvic acid in rat brain minces
    • Gibson, G. E., et al., 1975. Decreased synthesis of acetylcholine accompanying impaired oxidation of pyruvic acid in rat brain minces. Biochem J. 148, 17-23.
    • (1975) Biochem J. , vol.148 , pp. 17-23
    • Gibson, G.E.1
  • 34
    • 0020631789 scopus 로고
    • Cholinergic drugs and 4-aminopyridine alter hypoxic-induced behavioral deficits
    • Gibson, G. E., et al., 1983. Cholinergic drugs and 4-aminopyridine alter hypoxic-induced behavioral deficits. Pharmacol Biochem Behav. 18, 909-916.
    • (1983) Pharmacol Biochem Behav. , vol.18 , pp. 909-916
    • Gibson, G.E.1
  • 35
    • 0021169712 scopus 로고
    • Correlation of enzymatic, metabolic, and behavioral deficits in thiamin deficiency and its reversal
    • Gibson, G. E., et al., 1984. Correlation of enzymatic, metabolic, and behavioral deficits in thiamin deficiency and its reversal. Neurochem Res. 9, 803-814.
    • (1984) Neurochem Res. , vol.9 , pp. 803-814
    • Gibson, G.E.1
  • 36
    • 0023732664 scopus 로고
    • Reduced activities of thiamine-dependent enzymes in the brains and peripheral tissues of patients with Alzheimer's disease
    • Gibson, G. E., et al., 1988. Reduced activities of thiamine-dependent enzymes in the brains and peripheral tissues of patients with Alzheimer's disease. Arch Neurol. 45, 836-840.
    • (1988) Arch Neurol. , vol.45 , pp. 836-840
    • Gibson, G.E.1
  • 37
    • 0024552754 scopus 로고
    • Regionally selective alterations in enzymatic activities and metabolic fluxes during thiamin deficiency
    • Gibson, G., et al., 1989. Regionally selective alterations in enzymatic activities and metabolic fluxes during thiamin deficiency. Neurochem Res. 14, 17-24.
    • (1989) Neurochem Res. , vol.14 , pp. 17-24
    • Gibson, G.1
  • 38
    • 0033382224 scopus 로고    scopus 로고
    • Oxidative stress and a key metabolic enzyme in Alzheimer brains, cultured cells, and an animal model of chronic oxidative deficits
    • Gibson, G. E., et al., 1999. Oxidative stress and a key metabolic enzyme in Alzheimer brains, cultured cells, and an animal model of chronic oxidative deficits. Ann N Y Acad Sci. 893, 79-94.
    • (1999) Ann N Y Acad Sci. , vol.893 , pp. 79-94
    • Gibson, G.E.1
  • 39
    • 0344838535 scopus 로고    scopus 로고
    • Deficits in a tricarboxylic acid cycle enzyme in brains from patients with Parkinson's disease
    • Gibson, G. E., et al., 2003. Deficits in a tricarboxylic acid cycle enzyme in brains from patients with Parkinson's disease. Neurochem Int. 43, 129-135.
    • (2003) Neurochem Int. , vol.43 , pp. 129-135
    • Gibson, G.E.1
  • 40
    • 0344837347 scopus 로고    scopus 로고
    • Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy
    • Hammes, H. P., et al., 2003. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy. Nat Med. 9, 294-299.
    • (2003) Nat Med. , vol.9 , pp. 294-299
    • Hammes, H.P.1
  • 41
    • 12244274983 scopus 로고    scopus 로고
    • Downregulation of complexin I and complexin II in the medial thalamus is blocked by N-acetylcysteine in experimental Wernicke's encephalopathy
    • Hazell, A. S., Wang, C., 2005. Downregulation of complexin I and complexin II in the medial thalamus is blocked by N-acetylcysteine in experimental Wernicke's encephalopathy. J Neurosci Res. 79, 200-207.
    • (2005) J Neurosci Res. , vol.79 , pp. 200-207
    • Hazell, A.S.1    Wang, C.2
  • 42
    • 0027228515 scopus 로고
    • Cerebral vulnerability is associated with selective increase in extracellular glutamate concentration in experimental thiamine deficiency
    • Hazell, A. S., et al., 1993. Cerebral vulnerability is associated with selective increase in extracellular glutamate concentration in experimental thiamine deficiency. J Neurochem. 61, 1155-1158.
    • (1993) J Neurochem. , vol.61 , pp. 1155-1158
    • Hazell, A.S.1
  • 43
    • 0041804306 scopus 로고    scopus 로고
    • Thiamine deficiency results in downregulation of the GLAST glutamate transporter in cultured astrocytes
    • Hazell, A. S., et al., 2003. Thiamine deficiency results in downregulation of the GLAST glutamate transporter in cultured astrocytes. Glia. 43, 175-184.
    • (2003) Glia. , vol.43 , pp. 175-184
    • Hazell, A.S.1
  • 44
    • 0029879390 scopus 로고    scopus 로고
    • Alterations of thiamine phosphorylation and of thiamine-dependent enzymes in Alzheimer's disease
    • Heroux, M., et al., 1996. Alterations of thiamine phosphorylation and of thiamine-dependent enzymes in Alzheimer's disease. Metab Brain Dis. 11, 81-88.
    • (1996) Metab Brain Dis. , vol.11 , pp. 81-88
    • Heroux, M.1
  • 45
    • 0141481850 scopus 로고    scopus 로고
    • Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death
    • Huang, H. M., et al., 2003. Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death. J Neurosci Res. 74, 309-317.
    • (2003) J Neurosci Res. , vol.74 , pp. 309-317
    • Huang, H.M.1
  • 46
    • 84919843874 scopus 로고    scopus 로고
    • Selective antioxidants differentially modify endoplasmic reticulum Ca2+ stores and capacitative calcium entry
    • Huang, H. M., et al., 2005. Selective antioxidants differentially modify endoplasmic reticulum Ca2+ stores and capacitative calcium entry. Soc Neurosci. 35, 93-100.
    • (2005) Soc Neurosci. , vol.35 , pp. 93-100
    • Huang, H.M.1
  • 47
    • 13244298404 scopus 로고    scopus 로고
    • Inhibition of the alpha-ketoglutarate dehydrogenase complex by the myeloperoxidase products, hypochlorous acid and mono-N-chloramine
    • Jeitner, T. M., et al., 2005. Inhibition of the alpha-ketoglutarate dehydrogenase complex by the myeloperoxidase products, hypochlorous acid and mono-N-chloramine. J Neurochem. 92, 302-310.
    • (2005) J Neurochem. , vol.92 , pp. 302-310
    • Jeitner, T.M.1
  • 48
    • 0344117554 scopus 로고    scopus 로고
    • Cerebrospinal fluid levels of thiamine in patients with Parkinson's disease
    • Jimenez-Jimenez, F. J., et al., 1999. Cerebrospinal fluid levels of thiamine in patients with Parkinson's disease. Neurosci Lett. 271, 33-36.
    • (1999) Neurosci Lett. , vol.271 , pp. 33-36
    • Jimenez-Jimenez, F.J.1
  • 49
    • 23744478659 scopus 로고    scopus 로고
    • High-dose thiamine therapy counters dyslipidemia and advanced glycation of plasma protein in streptozotocin-induced diabetic rats
    • Karachalias, N., et al., 2005. High-dose thiamine therapy counters dyslipidemia and advanced glycation of plasma protein in streptozotocin-induced diabetic rats. Ann N Y Acad Sci. 1043, 777-783.
    • (2005) Ann N Y Acad Sci. , vol.1043 , pp. 777-783
    • Karachalias, N.1
  • 50
    • 0016758910 scopus 로고
    • Experimental thiamine deficiency. Neuropathic and mitochondrial changes induced in rat muscle
    • Kark, R. A., et al., 1975. Experimental thiamine deficiency. Neuropathic and mitochondrial changes induced in rat muscle. Arch Neurol. 32, 818-825.
    • (1975) Arch Neurol. , vol.32 , pp. 818-825
    • Kark, R.A.1
  • 51
    • 84919871593 scopus 로고    scopus 로고
    • Mild impairment of oxidative metabolism exacerbates pathology in a transgenic model of plaque formation
    • Karuppagounder, S. S., et al., 2006. Mild impairment of oxidative metabolism exacerbates pathology in a transgenic model of plaque formation. Soc Neurosci. 36, 170-715.
    • (2006) Soc Neurosci. , vol.36 , pp. 170-715
    • Karuppagounder, S.S.1
  • 52
    • 34147093749 scopus 로고    scopus 로고
    • Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism
    • Karuppagounder, S. S., et al., 2007. Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism. Neurobiol Dis. 26, 353-362.
    • (2007) Neurobiol Dis. , vol.26 , pp. 353-362
    • Karuppagounder, S.S.1
  • 53
    • 44549083055 scopus 로고    scopus 로고
    • Translocation of Amyloid Precursor Protein C-terminal Fragment (s) to the Nucleus Precedes Neuronal Death due to Thiamine Deficiency-induced Mild Impairment of Oxidative Metabolism
    • Karuppagounder, S. S., et al., 2008. Translocation of Amyloid Precursor Protein C-terminal Fragment (s) to the Nucleus Precedes Neuronal Death due to Thiamine Deficiency-induced Mild Impairment of Oxidative Metabolism. Neurochemical research, 33, 1365-1372.
    • (2008) Neurochemical Research , vol.33 , pp. 1365-1372
    • Karuppagounder, S.S.1
  • 54
    • 2442433959 scopus 로고    scopus 로고
    • Selective response of various brain cell types during neurodegeneration induced by mild impairment of oxidative metabolism
    • Ke, Z. J., Gibson, G. E., 2004. Selective response of various brain cell types during neurodegeneration induced by mild impairment of oxidative metabolism. Neurochem Int. 45, 361-369.
    • (2004) Neurochem Int. , vol.45 , pp. 361-369
    • Ke, Z.J.1    Gibson, G.E.2
  • 55
    • 0037317426 scopus 로고    scopus 로고
    • Reversal of thiamine deficiency-induced neurodegeneration
    • Ke, Z. J., et al., 2003. Reversal of thiamine deficiency-induced neurodegeneration. J Neuropathol Exp Neurol. 62, 195-207.
    • (2003) J Neuropathol Exp Neurol. , vol.62 , pp. 195-207
    • Ke, Z.J.1
  • 56
    • 20544475400 scopus 로고    scopus 로고
    • CD40-CD40L interactions promote neuronal death in a model of neurodegeneration due to mild impairment of oxidative metabolism
    • Ke, Z. J., et al., 2005a. CD40-CD40L interactions promote neuronal death in a model of neurodegeneration due to mild impairment of oxidative metabolism. Neurochem Int. 47, 204-215.
    • (2005) Neurochem Int. , vol.47 , pp. 204-215
    • Ke, Z.J.1
  • 57
    • 20444474033 scopus 로고    scopus 로고
    • CD40L deletion delays neuronal death in a model of neurodegeneration due to mild impairment of oxidative metabolism
    • Ke, Z. J., et al., 2005b. CD40L deletion delays neuronal death in a model of neurodegeneration due to mild impairment of oxidative metabolism. J Neuroimmunol. 164, 85-92.
    • (2005) J Neuroimmunol. , vol.164 , pp. 85-92
    • Ke, Z.J.1
  • 58
    • 33746878868 scopus 로고    scopus 로고
    • Peripheral inflammatory mechanisms modulate microglial activation in response to mild impairment of oxidative metabolism
    • Ke, Z. J., et al., 2006. Peripheral inflammatory mechanisms modulate microglial activation in response to mild impairment of oxidative metabolism. Neurochem Int. 49, 548-556.
    • (2006) Neurochem Int. , vol.49 , pp. 548-556
    • Ke, Z.J.1
  • 59
    • 12144290495 scopus 로고    scopus 로고
    • Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity
    • Klivenyi, P., et al., 2004. Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity. J Neurochem. 88, 1352-1360.
    • (2004) J Neurochem. , vol.88 , pp. 1352-1360
    • Klivenyi, P.1
  • 60
    • 0025426344 scopus 로고
    • Protective effects of the glutamate antagonist MK-801 on pyrithiamine-induced lesions and amino acid changes in rat brain
    • Langlais, P. J., Mair, R. G., 1990. Protective effects of the glutamate antagonist MK-801 on pyrithiamine-induced lesions and amino acid changes in rat brain. J Neurosci. 10, 1664-1674.
    • (1990) J Neurosci. , vol.10 , pp. 1664-1674
    • Langlais, P.J.1    Mair, R.G.2
  • 61
    • 0028930149 scopus 로고
    • Thiamine deficiency in rats produces cognitive and memory deficits on spatial tasks that correlate with tissue loss in diencephalon, cortex and white matter
    • Langlais, P. J., Savage, L. M., 1995. Thiamine deficiency in rats produces cognitive and memory deficits on spatial tasks that correlate with tissue loss in diencephalon, cortex and white matter. Behav Brain Res. 68, 75-89.
    • (1995) Behav Brain Res. , vol.68 , pp. 75-89
    • Langlais, P.J.1    Savage, L.M.2
  • 62
    • 33644694220 scopus 로고    scopus 로고
    • Thiamin deficiency: A possible major cause of some tumors? (review)
    • Lee, B. Y., et al., 2005. Thiamin deficiency: a possible major cause of some tumors? (review). Oncol Rep. 14, 1589-1592.
    • (2005) Oncol Rep. , vol.14 , pp. 1589-1592
    • Lee, B.Y.1
  • 63
    • 12244289642 scopus 로고    scopus 로고
    • Pyruvate dehydrogenase complex: Metabolic link to ischemic brain injury and target of oxidative stress
    • Martin, E., et al., 2005. Pyruvate dehydrogenase complex: metabolic link to ischemic brain injury and target of oxidative stress. J Neurosci Res. 79, 240-247.
    • (2005) J Neurosci Res. , vol.79 , pp. 240-247
    • Martin, E.1
  • 64
    • 0028229120 scopus 로고
    • Cerebellar alpha-ketoglutarate dehydrogenase activity is reduced in spinocerebellar ataxia type 1
    • Mastrogiacomo, F., Kish, S. J., 1994. Cerebellar alpha-ketoglutarate dehydrogenase activity is reduced in spinocerebellar ataxia type 1. Ann Neurol. 35, 624-626.
    • (1994) Ann Neurol. , vol.35 , pp. 624-626
    • Mastrogiacomo, F.1    Kish, S.J.2
  • 65
    • 7644226719 scopus 로고    scopus 로고
    • NAD+ modulates p53 DNA binding specificity and function
    • McLure, K. G., et al., 2004. NAD+ modulates p53 DNA binding specificity and function. Mol Cell Biol. 24, 9958-9967.
    • (2004) Mol Cell Biol. , vol.24 , pp. 9958-9967
    • McLure, K.G.1
  • 66
    • 0034628966 scopus 로고    scopus 로고
    • Increased histamine release and granulocytes within the thalamus of a rat model of Wernicke's encephalopathy
    • McRee, R. C., et al., 2000. Increased histamine release and granulocytes within the thalamus of a rat model of Wernicke's encephalopathy. Brain Res. 858, 227-236.
    • (2000) Brain Res. , vol.858 , pp. 227-236
    • McRee, R.C.1
  • 67
    • 0037355990 scopus 로고    scopus 로고
    • Neuropathological study of the role of mast cells and histaminepositive neurons in selective vulnerability of the thalamus and inferior colliculus in thiaminedeficient encephalopathy
    • Meng, J. S., Okeda, R., 2003. Neuropathological study of the role of mast cells and histaminepositive neurons in selective vulnerability of the thalamus and inferior colliculus in thiaminedeficient encephalopathy. Neuropathology. 23, 25-35.
    • (2003) Neuropathology. , vol.23 , pp. 25-35
    • Meng, J.S.1    Okeda, R.2
  • 68
    • 0034060762 scopus 로고    scopus 로고
    • Immunohistochemical estimation of brain choline acetyltransferase and somatostatin related to the impairment of avoidance learning induced by thiamine deficiency
    • Nakagawasai, O., et al., 2000a. Immunohistochemical estimation of brain choline acetyltransferase and somatostatin related to the impairment of avoidance learning induced by thiamine deficiency. Brain Res Bull. 52, 189-196.
    • (2000) Brain Res Bull. , vol.52 , pp. 189-196
    • Nakagawasai, O.1
  • 69
    • 0033971516 scopus 로고    scopus 로고
    • Immunohistochemical estimation of rat brain somatostatin on avoidance learning impairment induced by thiamine deficiency
    • Nakagawasai, O., et al., 2000b. Immunohistochemical estimation of rat brain somatostatin on avoidance learning impairment induced by thiamine deficiency. Brain Res Bull. 51, 47-55.
    • (2000) Brain Res Bull. , vol.51 , pp. 47-55
    • Nakagawasai, O.1
  • 70
    • 0035053717 scopus 로고    scopus 로고
    • Thiamine-responsive megaloblastic anemia syndrome: A disorder of high-affinity thiamine transport
    • Neufeld, E. J., et al., 2001. Thiamine-responsive megaloblastic anemia syndrome: a disorder of high-affinity thiamine transport. Blood Cells Mol Dis. 27, 135-138.
    • (2001) Blood Cells Mol Dis. , vol.27 , pp. 135-138
    • Neufeld, E.J.1
  • 71
    • 0034667742 scopus 로고    scopus 로고
    • Thiamine deficiency results in metabolic acidosis and energy failure in cerebellar granule cells: An in vitro model for the study of cell death mechanisms in Wernicke's encephalopathy
    • Pannunzio, P., et al., 2000. Thiamine deficiency results in metabolic acidosis and energy failure in cerebellar granule cells: an in vitro model for the study of cell death mechanisms in Wernicke's encephalopathy. J Neurosci Res. 62, 286-292.
    • (2000) J Neurosci Res. , vol.62 , pp. 286-292
    • Pannunzio, P.1
  • 72
    • 0033985184 scopus 로고    scopus 로고
    • Metabolic impairment elicits brain cell type-selective changes in oxidative stress and cell death in culture
    • Park, L. C., et al., 2000. Metabolic impairment elicits brain cell type-selective changes in oxidative stress and cell death in culture. J Neurochem. 74, 114-124.
    • (2000) J Neurochem. , vol.74 , pp. 114-124
    • Park, L.C.1
  • 73
    • 0035576822 scopus 로고    scopus 로고
    • Mitochondrial impairment in the cerebellum of the patients with progressive supranuclear palsy
    • Park, L. C., et al., 2001a. Mitochondrial impairment in the cerebellum of the patients with progressive supranuclear palsy. J Neurosci Res. 66, 1028-1034.
    • (2001) J Neurosci Res. , vol.66 , pp. 1028-1034
    • Park, L.C.1
  • 74
    • 0034788741 scopus 로고    scopus 로고
    • Co-culture with astrocytes or microglia protects metabolically impaired neurons
    • Park, L. C., et al., 2001b. Co-culture with astrocytes or microglia protects metabolically impaired neurons. Mech Ageing Dev. 123, 21-27.
    • (2001) Mech Ageing Dev. , vol.123 , pp. 21-27
    • Park, L.C.1
  • 75
    • 0017736633 scopus 로고
    • Peripheral nerve changes in thiamine deficiency and starvation
    • Pawlik, F., et al., 1977. Peripheral nerve changes in thiamine deficiency and starvation. Acta Neuropathologica. 39, 211-218.
    • (1977) Acta Neuropathologica. , vol.39 , pp. 211-218
    • Pawlik, F.1
  • 76
    • 33750498471 scopus 로고    scopus 로고
    • Blunted hippocampal, but not striatal, acetylcholine efflux parallels learning impairment in diencephalic-lesioned rats
    • Roland, J. J., Savage, L. M., 2007. Blunted hippocampal, but not striatal, acetylcholine efflux parallels learning impairment in diencephalic-lesioned rats. Neurobiol Learn Mem. 87, 123-132.
    • (2007) Neurobiol Learn Mem. , vol.87 , pp. 123-132
    • Roland, J.J.1    Savage, L.M.2
  • 77
    • 33847295123 scopus 로고    scopus 로고
    • Selective septohippocampal - But not forebrain amygdalar - Cholinergic dysfunction in diencephalic amnesia
    • Savage, L. M., et al., 2007. Selective septohippocampal - but not forebrain amygdalar - cholinergic dysfunction in diencephalic amnesia. Brain Res. 1139, 210-219.
    • (2007) Brain Res. , vol.1139 , pp. 210-219
    • Savage, L.M.1
  • 78
    • 33646382095 scopus 로고    scopus 로고
    • Free radical-mediated neurotoxicity may be caused by inhibition of mitochondrial dehydrogenases in vitro and in vivo
    • Sheline, C. T., Wei, L., 2006. Free radical-mediated neurotoxicity may be caused by inhibition of mitochondrial dehydrogenases in vitro and in vivo. Neuroscience. 140, 235-246.
    • (2006) Neuroscience. , vol.140 , pp. 235-246
    • Sheline, C.T.1    Wei, L.2
  • 79
    • 0036322455 scopus 로고    scopus 로고
    • Cofactors of mitochondrial enzymes attenuate copper-induced death in vitro and in vivo
    • Sheline, C. T., et al., 2002. Cofactors of mitochondrial enzymes attenuate copper-induced death in vitro and in vivo. Ann Neurol. 52, 195-204.
    • (2002) Ann Neurol. , vol.52 , pp. 195-204
    • Sheline, C.T.1
  • 80
    • 0030017492 scopus 로고    scopus 로고
    • Regional reductions of transketolase in thiamine-deficient rat brain
    • Sheu, K. F., et al., 1996. Regional reductions of transketolase in thiamine-deficient rat brain. J Neurochem. 67, 684-691.
    • (1996) J Neurochem. , vol.67 , pp. 684-691
    • Sheu, K.F.1
  • 81
    • 34250790605 scopus 로고    scopus 로고
    • Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability
    • Shi, Q., et al., 2007. Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability. Neurochem Int. 50, 921-931.
    • (2007) Neurochem Int. , vol.50 , pp. 921-931
    • Shi, Q.1
  • 82
    • 11444254472 scopus 로고    scopus 로고
    • Thiamine attenuates hypoxia-induced cell death in cultured neonatal rat cardiomyocytes
    • Shin, B. H., et al., 2004. Thiamine attenuates hypoxia-induced cell death in cultured neonatal rat cardiomyocytes. Mol Cells. 18, 133-140.
    • (2004) Mol Cells. , vol.18 , pp. 133-140
    • Shin, B.H.1
  • 83
    • 0025985636 scopus 로고
    • Anti-ischemic heart protection using thiamine and nicotinamide
    • Shneider, A. B., 1991. [Anti-ischemic heart protection using thiamine and nicotinamide]. Patol Fiziol Eksp Ter. 9-10.
    • (1991) Patol Fiziol Eksp Ter. , pp. 9-10
    • Shneider, A.B.1
  • 84
    • 4544359913 scopus 로고    scopus 로고
    • Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species
    • Starkov, A. A., et al., 2004. Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. J Neurosci. 24, 7779-2788.
    • (2004) J Neurosci. , vol.24 , pp. 7779-2788
    • Starkov, A.A.1
  • 85
    • 0033556271 scopus 로고    scopus 로고
    • Early microglial response in experimental thiamine deficiency: An immunohistochemical analysis
    • Todd, K. G., Butterworth, R. F., 1999. Early microglial response in experimental thiamine deficiency: an immunohistochemical analysis. Glia. 25, 190-198.
    • (1999) Glia. , vol.25 , pp. 190-198
    • Todd, K.G.1    Butterworth, R.F.2
  • 86
    • 33845802119 scopus 로고    scopus 로고
    • Severe thiamine deficiency resulted in Wernicke's encephalopathy in a chronic dialysis patient
    • Ueda, K., et al., 2006. Severe thiamine deficiency resulted in Wernicke's encephalopathy in a chronic dialysis patient. Clin Exp Nephrol. 10, 290-293.
    • (2006) Clin Exp Nephrol. , vol.10 , pp. 290-293
    • Ueda, K.1
  • 87
    • 0015179927 scopus 로고
    • The Wernicke-Korsakoff syndrome. A clinical and pathological study of 245 patients, 82 with post-mortem examinations
    • Victor, M., et al., 1971. The Wernicke-Korsakoff syndrome. A clinical and pathological study of 245 patients, 82 with post-mortem examinations. Contemp Neurol Ser. 7, 1-206.
    • (1971) Contemp Neurol Ser. , vol.7 , pp. 1-206
    • Victor, M.1
  • 88
    • 38849174504 scopus 로고    scopus 로고
    • Effect of ascorbic acid and thiamine supplementation at different concentrations on lead toxicity in liver
    • Wang, C., et al., 2007a. Effect of ascorbic acid and thiamine supplementation at different concentrations on lead toxicity in liver. Ann Occup Hyg. 51, 563-569.
    • (2007) Ann Occup Hyg. , vol.51 , pp. 563-569
    • Wang, C.1
  • 89
    • 36448942200 scopus 로고    scopus 로고
    • Activation of double-stranded RNA-activated protein kinase by mild impairment of oxidative metabolism in neurons
    • Wang, X., et al., 2007b. Activation of double-stranded RNA-activated protein kinase by mild impairment of oxidative metabolism in neurons. J Neurochem. 103, 2380-2390.
    • (2007) J Neurochem. , vol.103 , pp. 2380-2390
    • Wang, X.1
  • 90
    • 33845742025 scopus 로고    scopus 로고
    • Thiamine deficiency induces endoplasmic reticulum stress in neurons
    • Wang, X., et al., 2007c. Thiamine deficiency induces endoplasmic reticulum stress in neurons. Neuroscience. 144, 1045-1056.
    • (2007) Neuroscience. , vol.144 , pp. 1045-1056
    • Wang, X.1
  • 91
    • 0025011401 scopus 로고
    • Enzyme activities in relation to pH and lactate in postmortem brain in Alzheimer-type and other dementias
    • Yates, C. M., et al., 1990. Enzyme activities in relation to pH and lactate in postmortem brain in Alzheimer-type and other dementias. J Neurochem. 55, 1624-1630.
    • (1990) J Neurochem. , vol.55 , pp. 1624-1630
    • Yates, C.M.1
  • 92
    • 38149092393 scopus 로고    scopus 로고
    • Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stage
    • Zhao, N., et al., 2007. Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stage. Neurobiol Dis. 29, 176-185.
    • (2007) Neurobiol Dis. , vol.29 , pp. 176-185
    • Zhao, N.1


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