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Volumn 50, Issue 5, 2011, Pages 293-303

Dietary nitrite and nitrate: A review of potential mechanisms of cardiovascular benefits

Author keywords

Cardiovascular disease; Diet; Endothelial dysfunction; Nitrate; Nitric oxide; Nitrite

Indexed keywords

C REACTIVE PROTEIN; DRINKING WATER; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRATE; NITRIC OXIDE; NITRITE;

EID: 80053614218     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-011-0192-5     Document Type: Review
Times cited : (107)

References (109)
  • 1
    • 0030940959 scopus 로고    scopus 로고
    • Fruit and vegetables, and cardiovascular disease: A review
    • DOI 10.1093/ije/26.1.1
    • Ness AR, Powles JW (1997) Fruit and vegetables, and cardiovascular disease: a review. Int J Epidemiol 26:1-13 (Pubitemid 27129563)
    • (1997) International Journal of Epidemiology , vol.26 , Issue.1 , pp. 1-13
    • Ness, A.R.1    Powles, J.W.2
  • 2
    • 0034001951 scopus 로고    scopus 로고
    • Fruits and vegetables in the prevention of cancer and cardiovascular disease
    • van't Veer P, Jansen MC, Klerk M, Kok FJ (2000) Fruits and vegetables in the prevention of cancer and cardiovascular disease. Public Health Nutr 3:103-107 (Pubitemid 30214564)
    • (2000) Public Health Nutrition , vol.3 , Issue.1 , pp. 103-107
    • Van't Veer, P.1    Jansen, M.C.2    Klerk, M.3    Kok, F.J.4
  • 3
    • 2942613313 scopus 로고    scopus 로고
    • Dietary intake of fruits and vegetables and risk of cardiovascular disease
    • Bazzano LA, Serdula MK, Liu S (2003) Dietary intake of fruits and vegetables and risk of cardiovascular disease. Curr Atheroscler Rep 5:492-499 (Pubitemid 38906746)
    • (2003) Current Atherosclerosis Reports , vol.5 , Issue.6 , pp. 492-499
    • Bazzano, L.A.1    Serdula, M.K.2    Liu, S.3
  • 4
    • 33750728904 scopus 로고    scopus 로고
    • The effects of macronutrients on blood pressure and lipids: An overview of the DASH and OmniHeart trials
    • DOI 10.1007/s11883-006-0020-1
    • Miller ER III, Erlinger TP, Appel LJ (2006) The effects of macronutrients on blood pressure and lipids: an overview of the DASH and OmniHeart trials. Curr Atheroscler Rep 8:460-465 (Pubitemid 44697798)
    • (2006) Current Atherosclerosis Reports , vol.8 , Issue.6 , pp. 460-465
    • Miller III, E.R.1    Erlinger, T.P.2    Appel, L.J.3
  • 5
    • 65249102362 scopus 로고    scopus 로고
    • A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease
    • Mente A, de Koning L, Shannon HS, Anand SS (2009) A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease. Arch Intern Med 169:659-669
    • (2009) Arch Intern Med , vol.169 , pp. 659-669
    • Mente, A.1    De Koning, L.2    Shannon, H.S.3    Anand, S.S.4
  • 8
    • 34250776600 scopus 로고    scopus 로고
    • Role of the anion nitrite in ischemia-reperfusion cytoprotection and therapeutics
    • DOI 10.1016/j.cardiores.2007.05.001, PII S0008636307002143
    • Dezfulian C, Raat N, Shiva S, Gladwin MT (2007) Role of the anion nitrite in ischemia-reperfusion cytoprotection and therapeutics. Cardiovasc Res 75:327-338 (Pubitemid 46961934)
    • (2007) Cardiovascular Research , vol.75 , Issue.2 , pp. 327-338
    • Dezfulian, C.1    Raat, N.2    Shiva, S.3    Gladwin, M.T.4
  • 9
    • 78049314586 scopus 로고    scopus 로고
    • Inorganic nitrate and the cardiovascular system
    • Kapil V, Webb AJ, Ahluwalia A (2010) Inorganic nitrate and the cardiovascular system. Heart 96:1703-1709
    • (2010) Heart , vol.96 , pp. 1703-1709
    • Kapil, V.1    Webb, A.J.2    Ahluwalia, A.3
  • 10
    • 38849162730 scopus 로고    scopus 로고
    • The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics
    • DOI 10.1038/nrd2466, PII NRD2466
    • Lundberg JO, Weitzberg E, Gladwin MT (2008) The nitratenitrite- nitric oxide pathway in physiology and therapeutics. Nat Rev Drug Discov 7:156-167 (Pubitemid 351194063)
    • (2008) Nature Reviews Drug Discovery , vol.7 , Issue.2 , pp. 156-167
    • Lundberg, J.O.1    Weitzberg, E.2    Gladwin, M.T.3
  • 11
    • 67349287799 scopus 로고    scopus 로고
    • Dietary sources of nitrite as a modulator of ischemia/reperfusion injury
    • Garg HK, Bryan NS (2009) Dietary sources of nitrite as a modulator of ischemia/reperfusion injury. Kidney Int 75:1140-1144
    • (2009) Kidney Int , vol.75 , pp. 1140-1144
    • Garg, H.K.1    Bryan, N.S.2
  • 12
    • 69949111622 scopus 로고    scopus 로고
    • NO generation from inorganic nitrate and nitrite: Role in physiology, nutrition and therapeutics
    • Lundberg JO, Weitzberg E (2009) NO generation from inorganic nitrate and nitrite: role in physiology, nutrition and therapeutics. Arch Pharm Res 32:1119-1126
    • (2009) Arch Pharm Res , vol.32 , pp. 1119-1126
    • Lundberg, J.O.1    Weitzberg, E.2
  • 13
    • 63849332234 scopus 로고    scopus 로고
    • Cardioprotective actions of nitrite therapy and dietary considerations
    • Bryan NS (2009) Cardioprotective actions of nitrite therapy and dietary considerations. Front Biosci 14:4793-4808
    • (2009) Front Biosci , vol.14 , pp. 4793-4808
    • Bryan, N.S.1
  • 16
    • 66149131355 scopus 로고    scopus 로고
    • Dietary nitrite prevents hypercholesterolemic microvascular inflammation and reverses endothelial dysfunction
    • Stokes KY, Dugas TR, Tang Y, Garg H, Guidry E, Bryan NS (2009) Dietary nitrite prevents hypercholesterolemic microvascular inflammation and reverses endothelial dysfunction. Am J Physiol Heart Circ Physiol 296:H1281-H1288
    • (2009) Am J Physiol Heart Circ Physiol , vol.296
    • Stokes, K.Y.1    Dugas, T.R.2    Tang, Y.3    Garg, H.4    Guidry, E.5    Bryan, N.S.6
  • 17
    • 46249130703 scopus 로고    scopus 로고
    • Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction
    • Gonzalez FM, Shiva S (2008) Nitrite anion provides potent cytoprotective and antiapoptotic effects as adjunctive therapy to reperfusion for acute myocardial infarction. Circulation 117: 2986-2994
    • (2008) Circulation , vol.117 , pp. 2986-2994
    • Gonzalez, F.M.1    Shiva, S.2
  • 21
    • 46649108907 scopus 로고    scopus 로고
    • Dietary nitrite restores NO homeostasis and is cardioprotective in endothelial nitric oxide synthase-deficient mice
    • Bryan NS, Calvert JW, Gundewar S, Lefer DJ (2008) Dietary nitrite restores NO homeostasis and is cardioprotective in endothelial nitric oxide synthase-deficient mice. Free Radic Biol Med 45:468-474
    • (2008) Free Radic Biol Med , vol.45 , pp. 468-474
    • Bryan, N.S.1    Calvert, J.W.2    Gundewar, S.3    Lefer, D.J.4
  • 23
    • 62249194823 scopus 로고    scopus 로고
    • Nitrite mediates cytoprotection after ischemia/reperfusion by modulating mitochondrial function
    • Shiva S, Gladwin MT (2009) Nitrite mediates cytoprotection after ischemia/reperfusion by modulating mitochondrial function. Basic Res Cardiol 104:113-119
    • (2009) Basic Res Cardiol , vol.104 , pp. 113-119
    • Shiva, S.1    Gladwin, M.T.2
  • 28
    • 77955476126 scopus 로고    scopus 로고
    • Inorganic nitrate supplementation lowers blood pressure in humans: Role for nitrite-derived NO
    • Kapil V, Milsom AB, Okorie M et al (2010) Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO. Hypertension 56:274-281
    • (2010) Hypertension , vol.56 , pp. 274-281
    • Kapil, V.1    Milsom, A.B.2    Okorie, M.3
  • 37
    • 0032346385 scopus 로고    scopus 로고
    • Dietary exposure models for nitrates and nitrites
    • Pennington JAT (1998) Dietary exposure models for nitrates and nitrites. Food Control 9:385-395
    • (1998) Food Control , vol.9 , pp. 385-395
    • Jat, P.1
  • 38
    • 0029075644 scopus 로고
    • Chemical generation of nitric oxide in the mouth from the enterosalivary circulation of dietary nitrate
    • Duncan C, Dougall H, Johnston P et al (1995) Chemical generation of nitric oxide in the mouth from the enterosalivary circulation of dietary nitrate. Nat Med 1:546-551
    • (1995) Nat Med , vol.1 , pp. 546-551
    • Duncan, C.1    Dougall, H.2    Johnston, P.3
  • 39
    • 0028932526 scopus 로고
    • The effect of amoxycillin on salivary nitrite concentrations: An important mechanism of adverse reactions?
    • Dougall HT, Smith L, Duncan C, Benjamin N (1995) The effect of amoxycillin on salivary nitrite concentrations: an important mechanism of adverse reactions? Br J Clin Pharmacol 39:460-462
    • (1995) Br J Clin Pharmacol , vol.39 , pp. 460-462
    • Dougall, H.T.1    Smith, L.2    Duncan, C.3    Benjamin, N.4
  • 40
    • 55549095980 scopus 로고    scopus 로고
    • The increase in plasma nitrite after a dietary nitrate load is markedly attenuated by an antibacterial mouthwash
    • Govoni M, Jansson EA, Weitzberg E, Lundberg JO (2008) The increase in plasma nitrite after a dietary nitrate load is markedly attenuated by an antibacterial mouthwash. Nitric Oxide 19:333-337
    • (2008) Nitric Oxide , vol.19 , pp. 333-337
    • Govoni, M.1    Jansson, E.A.2    Weitzberg, E.3    Lundberg, J.O.4
  • 42
    • 0032993339 scopus 로고    scopus 로고
    • Serum nitrite sensitively reflects endothelial NO formation in human forearm vasculature: Evidence for biochemical assessment of the endothelial L-arginine-NO pathway
    • DOI 10.1016/S0008-6363(98)00259-4, PII S0008636398002594
    • Kelm M, Preik-Steinhoff H, Preik M, Strauer BE (1999) Serum nitrite sensitively reflects endothelial NO formation in human forearm vasculature: evidence for biochemical assessment of the endothelial L-arginine-NO pathway. Cardiovasc Res 41:765-772 (Pubitemid 29130641)
    • (1999) Cardiovascular Research , vol.41 , Issue.3 , pp. 765-772
    • Kelm, M.1    Preik-Steinhoff, H.2    Preik, M.3    Strauer, B.E.4
  • 43
    • 1242351238 scopus 로고    scopus 로고
    • Circulating no pool: Assessment of nitrite and nitroso species in blood and tissues
    • DOI 10.1016/j.freeradbiomed.2003.11.011
    • Rassaf T, Feelisch M, Kelm M (2004) Circulating NO pool: assessment of nitrite and nitroso species in blood and tissues. Free Radic Biol Med 36:413-422 (Pubitemid 38224513)
    • (2004) Free Radical Biology and Medicine , vol.36 , Issue.4 , pp. 413-422
    • Rassaf, T.1    Feelisch, M.2    Kelm, M.3
  • 44
    • 79955671890 scopus 로고    scopus 로고
    • Measurement of nitrite in blood samples using the ferricyanide-based hemoglobin oxidation assay
    • Piknova B, Schechter AN (2011) Measurement of nitrite in blood samples using the ferricyanide-based hemoglobin oxidation assay. Methods Mol Biol 704:39-56
    • (2011) Methods Mol Biol , vol.704 , pp. 39-56
    • Piknova, B.1    Schechter, A.N.2
  • 46
    • 0017036773 scopus 로고
    • The effect of nitrate intake on nitrite formation in human saliva
    • Tannenbaum SR, Weisman M, Fett D (1976) The effect of nitrate intake on nitrite formation in human saliva. Food Cosmet Toxicol 14:549-552 (Pubitemid 8050598)
    • (1976) Food and Cosmetics Toxicology , vol.14 , Issue.6 , pp. 549-552
    • Tannenbaum, S.R.1    Weisman, M.2    Fett, D.3
  • 47
    • 0021178447 scopus 로고
    • The pharmacology of dietary nitrate and the origin of urinary nitrate
    • Bartholomew B, Hill MJ (1984) The pharmacology of dietary nitrate and the origin of urinary nitrate. Food Chem Toxicol 22:789-795 (Pubitemid 14022193)
    • (1984) Food and Chemical Toxicology , vol.22 , Issue.10 , pp. 789-795
    • Bartholomew, B.1    Hill, M.J.2
  • 48
    • 3042667643 scopus 로고    scopus 로고
    • Inorganic nitrate is a possible source for systemic generation of nitric oxide
    • DOI 10.1016/j.freeradbiomed.2004.04.027, PII S089158490400348X
    • Lundberg JO, Govoni M (2004) Inorganic nitrate is a possible source for systemic generation of nitric oxide. Free Radic Biol Med 37:395-400 (Pubitemid 38834005)
    • (2004) Free Radical Biology and Medicine , vol.37 , Issue.3 , pp. 395-400
    • Lundberg, J.O.1    Govoni, M.2
  • 51
    • 0032490711 scopus 로고    scopus 로고
    • Endothelial function in health and disease: New insights into the genesis of cardiovascular disease
    • PII S0002934398002095
    • Quyyumi AA (1998) Endothelial function in health and disease: new insights into the genesis of cardiovascular disease. Am J Med 105:32S-39S (Pubitemid 28364424)
    • (1998) American Journal of Medicine , vol.105 , Issue.1 A
    • Quyyumi, A.A.1
  • 52
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RMJ, Higgs EA (1991) Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43:109-142
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Rmj, P.2    Higgs, E.A.3
  • 53
    • 13844269298 scopus 로고    scopus 로고
    • The role of nitric oxide in cardiovascular diseases
    • DOI 10.1016/j.mam.2004.09.003
    • Naseem KM (2005) The role of nitric oxide in cardiovascular diseases. Mol Aspects Med 26:33-65 (Pubitemid 40250164)
    • (2005) Molecular Aspects of Medicine , vol.26 , Issue.1-2 SPEC. ISS. , pp. 33-65
    • Naseem, K.M.1
  • 54
    • 33645031783 scopus 로고    scopus 로고
    • Direct effects of quercetin on impaired reactivity of spontaneously hypertensive rat aortas: Comparative study with ascorbic acid
    • Ajay M, Achike FI, Mustafa AM, Mustafa MR (2006) Direct effects of quercetin on impaired reactivity of spontaneously hypertensive rat aortas: comparative study with ascorbic acid. Clin Exp Pharmacol Physiol 33:345-350
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 345-350
    • Ajay, M.1    Achike, F.I.2    Mustafa, A.M.3    Mustafa, M.R.4
  • 55
    • 33947497538 scopus 로고    scopus 로고
    • Endothelial dysfunction: Cardiovascular risk factors, therapy, and outcome
    • Hadi HAR, Carr CS, Suwaidi JA (2005) Endothelial dysfunction: cardiovascular risk factors, therapy, and outcome. Vasc Health Risk Manag 1:183-198
    • (2005) Vasc Health Risk Manag , vol.1 , pp. 183-198
    • Har, H.1    Carr, C.S.2    Suwaidi, J.A.3
  • 58
    • 0028143644 scopus 로고
    • Intragastric nitric oxide production in humans: Measurements in expelled air
    • Lundberg JO, Weitzberg E, Lundberg JM, Alving K (1994) Intragastric nitric oxide production in humans: measurements in expelled air. Gut 35:1543-1546 (Pubitemid 24339249)
    • (1994) Gut , vol.35 , Issue.11 , pp. 1543-1546
    • Lundberg, J.O.N.1    Weitzberg, E.2    Lundberg, J.M.3    Alving, K.4
  • 59
    • 0029114339 scopus 로고
    • Enzyme-independent formation of nitric oxide in biological tissues
    • Zweier JL, Wang P, Samouilov A, Kuppusamy P (1995) Enzyme-independent formation of nitric oxide in biological tissues. Nat Med 1:804-809
    • (1995) Nat Med , vol.1 , pp. 804-809
    • Zweier, J.L.1    Wang, P.2    Samouilov, A.3    Kuppusamy, P.4
  • 61
    • 0032496394 scopus 로고    scopus 로고
    • Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions
    • DOI 10.1016/S0014-5793(98)00430-X, PII S001457939800430X
    • Millar TM, Stevens CR, Benjamin N, Eisenthal R, Harrison R, Blake DR (1998) Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions. FEBS Lett 427:225-228 (Pubitemid 28225062)
    • (1998) FEBS Letters , vol.427 , Issue.2 , pp. 225-228
    • Millar, T.M.1    Stevens, C.R.2    Benjamin, N.3    Eisenthal, R.4    Harrison, R.5    Blake, D.R.6
  • 62
    • 33744964055 scopus 로고    scopus 로고
    • Characterization of the mechanism of cytochrome P450 reductase-cytochrome P450-mediated nitric oxide and nitrosothiol generation from organic nitrates
    • DOI 10.1074/jbc.M511803200
    • Li H, Liu X, Cui H, Chen YR, Cardounel AJ, Zweier JL (2006) Characterization of the mechanism of cytochrome P450 reductase- cytochrome P450-mediated nitric oxide and nitrosothiol generation from organic nitrates. J Biol Chem 281:12546-12554 (Pubitemid 43855342)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.18 , pp. 12546-12554
    • Li, H.1    Liu, X.2    Cui, H.3    Chen, Y.-R.4    Cardounel, A.J.5    Zweier, J.L.6
  • 63
    • 33645560710 scopus 로고    scopus 로고
    • Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: Implications for oxygen sensing and hypoxic signalling in eukaryotes
    • Castello P, David P, McClure T, Crook Z, Poyton R (2006) Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: implications for oxygen sensing and hypoxic signalling in eukaryotes. Cell Metab 3:277-287
    • (2006) Cell Metab , vol.3 , pp. 277-287
    • Castello, P.1    David, P.2    McClure, T.3    Crook, Z.4    Poyton, R.5
  • 64
    • 71749090061 scopus 로고    scopus 로고
    • Characterization of the magnitude and mechanism of aldehyde oxidase-mediated nitric oxide production from nitrite
    • Li H, Kundu TK, Zweier JL (2009) Characterization of the magnitude and mechanism of aldehyde oxidase-mediated nitric oxide production from nitrite. J Biol Chem 284:33850-33858
    • (2009) J Biol Chem , vol.284 , pp. 33850-33858
    • Li, H.1    Kundu, T.K.2    Zweier, J.L.3
  • 65
    • 72249108763 scopus 로고    scopus 로고
    • Generation of nitric oxide from nitrite by carbonic anhydrase: A possible link between metabolic activity and vasodilation
    • Aamand R, Dalsgaard T, Jensen FB, Simonsen U, Roepstorff A, Fago A (2009) Generation of nitric oxide from nitrite by carbonic anhydrase: a possible link between metabolic activity and vasodilation. Am J Physiol Heart Circ Physiol 297:H2068-H2074
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Aamand, R.1    Dalsgaard, T.2    Jensen, F.B.3    Simonsen, U.4    Roepstorff, A.5    Fago, A.6
  • 66
    • 0141742650 scopus 로고    scopus 로고
    • Quercetindependent reduction of salivary nitrite to nitric oxide under acidic conditions and interaction between quercetin and ascorbic acid during the reduction
    • Takahama U, Yamamoto A, Hirota S, Oniki T (2003) Quercetindependent reduction of salivary nitrite to nitric oxide under acidic conditions and interaction between quercetin and ascorbic acid during the reduction. J Agric Food Chem 51:6014-6020
    • (2003) J Agric Food Chem , vol.51 , pp. 6014-6020
    • Takahama, U.1    Yamamoto, A.2    Hirota, S.3    Oniki, T.4
  • 67
    • 40149109791 scopus 로고    scopus 로고
    • Oxidation of iron-nitrosyl-hemoglobin by dehydroascorbic acid releases nitric oxide to form nitrite in human erythrocytes
    • DOI 10.1021/bi702158d
    • Sibmooh N, Piknova B, Rizzatti F, Schechter AN (2008) Oxidation of iron-nitrosyl-hemoglobin by dehydroascorbic acid releases nitric oxide to form nitrite in human erythrocytes. Biochemistry 47:2989-2996 (Pubitemid 351328852)
    • (2008) Biochemistry , vol.47 , Issue.9 , pp. 2989-2996
    • Sibmooh, N.1    Piknova, B.2    Rizzatti, F.3    Schechter, A.N.4
  • 68
    • 67650715561 scopus 로고    scopus 로고
    • Nitrite as regulator of hypoxic signaling in mammalian physiology
    • van Faassen EE, Bahrami S, Feelisch M et al (2009) Nitrite as regulator of hypoxic signaling in mammalian physiology. Med Res Rev 29:683-741
    • (2009) Med Res Rev , vol.29 , pp. 683-741
    • Van Faassen, E.E.1    Bahrami, S.2    Feelisch, M.3
  • 69
    • 57749122061 scopus 로고    scopus 로고
    • Tissue processing of nitrite in hypoxia: An intricate interplay of nitric oxide-generating and -scavenging systems
    • Feelisch M, Fernandez BO, Bryan NS et al (2008) Tissue processing of nitrite in hypoxia: an intricate interplay of nitric oxide-generating and -scavenging systems. J Biol Chem 283: 33927-33934
    • (2008) J Biol Chem , vol.283 , pp. 33927-33934
    • Feelisch, M.1    Fernandez, B.O.2    Bryan, N.S.3
  • 70
    • 33646671928 scopus 로고    scopus 로고
    • Unraveling the reactions of nitric oxide, nitrite, and hemoglobin in physiology and therapeutics
    • DOI 10.1161/01.ATV.0000204350.44226.9a, PII 0004360520060400000006
    • Kim-Shapiro DB, Schechter AN, Gladwin MT (2006) Unraveling the reactions of nitric oxide, nitrite, and hemoglobin in physiology and therapeutics. Arterioscler Thromb Vasc Biol 26:697-705 (Pubitemid 43732141)
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.26 , Issue.4 , pp. 697-705
    • Kim-Shapiro, D.B.1    Schechter, A.N.2    Gladwin, M.T.3
  • 71
    • 0034633659 scopus 로고    scopus 로고
    • Role of circulating nitrite and S-nitrosohemoglobin in the regulation of regional blood flow in humans
    • Gladwin MT, Shelhamer JH, Schechter AN et al (2000) Role of circulating nitrite and S-nitrosohemoglobin in the regulation of regional blood flow in humans. Proc Natl Acad Sci U S A 97:11482-11487
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 11482-11487
    • Gladwin, M.T.1    Shelhamer, J.H.2    Schechter, A.N.3
  • 72
    • 0030219179 scopus 로고    scopus 로고
    • Decreased nitric oxide production following extremity ischemia and reperfusion
    • Blebea J, Bacik B, Strothman G, Myatt L (1996) Decreased nitric oxide production following extremity ischemia and reperfusion. Am J Surg 172:158-161
    • (1996) Am J Surg , vol.172 , pp. 158-161
    • Blebea, J.1    Bacik, B.2    Strothman, G.3    Myatt, L.4
  • 73
    • 0027396266 scopus 로고
    • Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium
    • Ma XL, Weyrich AS, Lefer DJ, Lefer AM (1993) Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium. Circ Res 72:403-412 (Pubitemid 23024528)
    • (1993) Circulation Research , vol.72 , Issue.2 , pp. 403-412
    • Ma, X.-I.1    Weyrich, A.S.2    Lefer, D.J.3    Lefer, A.M.4
  • 76
    • 18044383110 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in cardiovascular disease
    • DOI 10.1016/j.freeradbiomed.2005.02.014
    • Ballinger SW (2005) Mitochondrial dysfunction in cardiovascular disease. Free Radic Biol Med 38:1278-1295 (Pubitemid 40602831)
    • (2005) Free Radical Biology and Medicine , vol.38 , Issue.10 , pp. 1278-1295
    • Ballinger, S.W.1
  • 77
    • 33947512416 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in atherosclerosis
    • DOI 10.1161/01.RES.0000258450.44413.96, PII 0000301220070302000006
    • Madamanchi NR, Runge MS (2007) Mitochondrial dysfunction in atherosclerosis. Circ Res 100:460-473 (Pubitemid 46673256)
    • (2007) Circulation Research , vol.100 , Issue.4 , pp. 460-473
    • Madamanchi, N.R.1    Runge, M.S.2
  • 78
    • 68549112975 scopus 로고    scopus 로고
    • Mitochondriatargeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy
    • Graham D, Huynh NN, Hamilton CA et al (2009) Mitochondriatargeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy. Hypertension 54:322-328
    • (2009) Hypertension , vol.54 , pp. 322-328
    • Graham, D.1    Huynh, N.N.2    Hamilton, C.A.3
  • 80
    • 0033527413 scopus 로고    scopus 로고
    • Oxidation of tetrahydrobiopterin by peroxynitrite: Implications for vascular endothelial function
    • DOI 10.1006/bbrc.1999.1422
    • Milstien S, Katusic Z (1999) Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function. Biochem Biophys Res Commun 263:681-684 (Pubitemid 29490686)
    • (1999) Biochemical and Biophysical Research Communications , vol.263 , Issue.3 , pp. 681-684
    • Milstien, S.1    Katusic, Z.2
  • 81
    • 2442513360 scopus 로고    scopus 로고
    • Inflammation and endothelial dysfunction: Intimate companions in the pathogenesis of vascular disease?
    • DOI 10.1042/CS20040019
    • Sattar N (2004) Inflammation and endothelial dysfunction: intimate companions in the pathogenesis of vascular disease? Clin Sci (Lond) 106:443-445 (Pubitemid 38639545)
    • (2004) Clinical Science , vol.106 , Issue.5 , pp. 443-445
    • Sattar, N.1
  • 82
    • 69249242832 scopus 로고    scopus 로고
    • Human C-reactive protein induces endothelial dysfunction and uncoupling of eNOS in vivo
    • Hein TW, Singh U, Vasquez-Vivar J, Devaraj S, Kuo L, Jialal I (2009) Human C-reactive protein induces endothelial dysfunction and uncoupling of eNOS in vivo. Atherosclerosis 206:61-68
    • (2009) Atherosclerosis , vol.206 , pp. 61-68
    • Hein, T.W.1    Singh, U.2    Vasquez-Vivar, J.3    Devaraj, S.4    Kuo, L.5    Jialal, I.6
  • 83
    • 77957314718 scopus 로고    scopus 로고
    • The role of angiotensin receptor blocker and calcium channel blocker combination therapy in treating hypertension: Focus on recent studies
    • Chrysant SG (2010) The role of angiotensin receptor blocker and calcium channel blocker combination therapy in treating hypertension: focus on recent studies. Am J Cardiovasc Drugs 10:315-320
    • (2010) Am J Cardiovasc Drugs , vol.10 , pp. 315-320
    • Chrysant, S.G.1
  • 84
    • 33645129041 scopus 로고    scopus 로고
    • Calcium-channel modulators for cardiovascular disease
    • Godfraind T (2006) Calcium-channel modulators for cardiovascular disease. Expert Opin Emerg Drugs 11:49-73
    • (2006) Expert Opin Emerg Drugs , vol.11 , pp. 49-73
    • Godfraind, T.1
  • 85
    • 84918258075 scopus 로고
    • Reactions of strips of rabbit aorta to epinephrine, isopropylarterenol, sodium nitrite and other drugs
    • Furchgott RF, Bhadrakom S (1953) Reactions of strips of rabbit aorta to epinephrine, isopropylarterenol, sodium nitrite and other drugs. J Pharmacol Exp Ther 108:128-143
    • (1953) J Pharmacol Exp Ther , vol.108 , pp. 128-143
    • Furchgott, R.F.1    Bhadrakom, S.2
  • 86
    • 0013687266 scopus 로고
    • The nature of the collapse induced by sodium nitrite
    • Weiss S, Wilkins RW, Haynes FW (1937) The nature of the collapse induced by sodium nitrite. J Clin Invest 16:73-84
    • (1937) J Clin Invest , vol.16 , pp. 73-84
    • Weiss, S.1    Wilkins, R.W.2    Haynes, F.W.3
  • 88
    • 0026068607 scopus 로고
    • Exogenous GTP enhances the effects of sodium nitrite on cyclic GMP accumulation, vascular smooth muscle relaxation and platelet aggregation
    • Laustiola KE, Vuorinen P, Porsti I, Metsa-Ketela T, Manninen V, Vapaatalo H (1991) Exogenous GTP enhances the effects of sodium nitrite on cyclic GMP accumulation, vascular smooth muscle relaxation and platelet aggregation. Pharmacol Toxicol 68:60-63
    • (1991) Pharmacol Toxicol , vol.68 , pp. 60-63
    • Laustiola, K.E.1    Vuorinen, P.2    Porsti, I.3    Metsa-Ketela, T.4    Manninen, V.5    Vapaatalo, H.6
  • 90
    • 0019448891 scopus 로고
    • Methylene blue inhibits coronary arterial relaxation and guanylate cyclase activation by nitroglycerin, sodium nitrite, and amyl nitrite
    • Gruetter CA, Kadowitz PJ, Ignarro LJ (1981) Methylene blue inhibits coronary arterial relaxation and guanylate cyclase activation by nitroglycerin, sodium nitrite, and amyl nitrite. Can J Physiol Pharmacol 59:150-156 (Pubitemid 11152379)
    • (1981) Canadian Journal of Physiology and Pharmacology , vol.59 , Issue.2 , pp. 150-156
    • Gruetter, C.A.1    Kadowitz, P.J.2    Ignarro, L.J.3
  • 91
    • 70350343133 scopus 로고    scopus 로고
    • Nitrite directly vasodilates hypoxic vasculature via nitric oxidedependent and -independent pathways
    • Pinder AG, Pittaway E, Morris K, James PE (2009) Nitrite directly vasodilates hypoxic vasculature via nitric oxidedependent and -independent pathways. Br J Pharmacol 157: 1523-1530
    • (2009) Br J Pharmacol , vol.157 , pp. 1523-1530
    • Pinder, A.G.1    Pittaway, E.2    Morris, K.3    James, P.E.4
  • 92
    • 33745206713 scopus 로고
    • Vaso-dilators in high blood pressure
    • Matthew E (1908) Vaso-dilators in high blood pressure. Q J Med 2:261-270
    • (1908) Q J Med , vol.2 , pp. 261-270
    • Matthew, E.1
  • 93
    • 0000991632 scopus 로고
    • Acquired tolerance to and cross tolerance between the nitrous and nitric acid esters and sodium nitrite in man
    • Crandall LA Jr, Leake CD, Loevenhart AS, Muehlberger CW (1931) Acquired tolerance to and cross tolerance between the nitrous and nitric acid esters and sodium nitrite in man. J Pharmacol Exp Ther 41:103-119
    • (1931) J Pharmacol Exp Ther , vol.41 , pp. 103-119
    • Crandall Jr., L.A.1    Leake, C.D.2    Loevenhart, A.S.3    Muehlberger, C.W.4
  • 94
    • 0036036981 scopus 로고    scopus 로고
    • The ingestion of inorganic nitrate increases gastric S-nitrosothiol levels and inhibits platelet function in humans
    • DOI 10.1016/S1089-8603(02)00010-1, PII S1089860302000101
    • Richardson G, Hicks SL, O'Byrne S, Frost MT, Moore K, Benjamin N, McKnight GM (2002) The ingestion of inorganic nitrate increases gastric S-nitrosothiol levels and inhibits platelet function in humans. Nitric Oxide 7:24-29 (Pubitemid 35007256)
    • (2002) Nitric Oxide - Biology and Chemistry , vol.7 , Issue.1 , pp. 24-29
    • Richardson, G.1    Hicks, S.L.2    O'Byrne, S.3    Frost, M.T.4    Moore, K.5    Benjamin, N.6    McKnight, G.M.7
  • 97
    • 63049130956 scopus 로고    scopus 로고
    • Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwash
    • Petersson J, Carlstrom M, Schreiber O et al (2009) Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwash. Free Radic Biol Med 46:1068-1075
    • (2009) Free Radic Biol Med , vol.46 , pp. 1068-1075
    • Petersson, J.1    Carlstrom, M.2    Schreiber, O.3
  • 98
    • 75149158338 scopus 로고    scopus 로고
    • Dietary nitrate in Japanese traditional foods lowers diastolic blood pressure in healthy volunteers
    • Sobko T, Marcus C, Govoni M, Kamiya S (2010) Dietary nitrate in Japanese traditional foods lowers diastolic blood pressure in healthy volunteers. Nitric Oxide 22:136-140
    • (2010) Nitric Oxide , vol.22 , pp. 136-140
    • Sobko, T.1    Marcus, C.2    Govoni, M.3    Kamiya, S.4
  • 100
    • 33750934803 scopus 로고    scopus 로고
    • Early intravenous infusion of sodium nitrite protects brain against in vivo ischemia-reperfusion injury
    • DOI 10.1161/01.STR.0000245116.40163.1c, PII 0000767020061100000027
    • Jung KH, Chu K, Ko SY et al (2006) Early intravenous infusion of sodium nitrite protects brain against in vivo ischemia-reperfusion injury. Stroke 37:2744-2750 (Pubitemid 44922536)
    • (2006) Stroke , vol.37 , Issue.11 , pp. 2744-2750
    • Jung, K.-H.1    Chu, K.2    Ko, S.-Y.3    Lee, S.-T.4    Sinn, D.-I.5    Park, D.-K.6    Kim, J.-M.7    Song, E.-C.8    Kim, M.9    Roh, J.-K.10
  • 101
    • 0017046438 scopus 로고
    • Influence of dietary nitrate on nitrite content of human saliva: Possible relevance to in vivo formation of N nitroso compounds
    • Spiegelhalder B, Eisenbrand G, Preussmann R (1976) Influence of dietary nitrate on nitrite content of human saliva: possible relevance to in vivo formation of N-nitroso compounds. Food Cosmet Toxicol 14:545-548 (Pubitemid 8050597)
    • (1976) Food and Cosmetics Toxicology , vol.14 , Issue.6 , pp. 545-548
    • Spiegelhalder, B.1    Eisenbrand, G.2    Preussmann, R.3
  • 102
    • 0025256874 scopus 로고
    • Nitrosamines as potential environmental carcinogens in man
    • Lin JK (1990) Nitrosamines as potential environmental carcinogens in man. Clin Biochem 23:67-71 (Pubitemid 20134416)
    • (1990) Clinical Biochemistry , vol.23 , Issue.1 , pp. 67-71
    • Lin, J.K.1
  • 105
    • 0031959619 scopus 로고    scopus 로고
    • Dietary nitrates, nitrites, and N-nitroso compounds and cancer risk: A review of the epidemiologic evidence
    • Eichholzer M, Gutzwiller F (1998) Dietary nitrates, nitrites, and N-nitroso compounds and cancer risk: a review of the epidemiologic evidence. Nutr Rev 56:95-105 (Pubitemid 28209801)
    • (1998) Nutrition Reviews , vol.56 , Issue.4 , pp. 95-105
    • Eichholzer, M.1    Gutzwiller, F.2
  • 106
    • 78751615379 scopus 로고    scopus 로고
    • Nitrite and nitrate: Cardiovascular risk-benefit and metabolic effect
    • Tang Y, Jiang H, Bryan NS (2011) Nitrite and nitrate: cardiovascular risk-benefit and metabolic effect. Curr Opin Lipidol 22:11-15
    • (2011) Curr Opin Lipidol , vol.22 , pp. 11-15
    • Tang, Y.1    Jiang, H.2    Bryan, N.S.3
  • 107
    • 77950215241 scopus 로고    scopus 로고
    • A large prospective study of meat consumption and colorectal cancer risk: An investigation of potential mechanisms underlying this association
    • Cross AJ, Ferrucci LM, Risch A et al (2010) A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this association. Cancer Res 70:2406-2414
    • (2010) Cancer Res , vol.70 , pp. 2406-2414
    • Cross, A.J.1    Ferrucci, L.M.2    Risch, A.3
  • 108
    • 77957369613 scopus 로고    scopus 로고
    • Meat and components of meat and the risk of bladder cancer in the NIH-AARP diet and health study
    • Ferrucci LM, Sinha R, Ward MH et al (2010) Meat and components of meat and the risk of bladder cancer in the NIH-AARP diet and health study. Cancer 116:4345-4353
    • (2010) Cancer , vol.116 , pp. 4345-4353
    • Ferrucci, L.M.1    Sinha, R.2    Ward, M.H.3
  • 109
    • 80053584274 scopus 로고
    • Abortion and possible risk for breast cancer: Analysis and inconsistencies
    • Anderson L (1994) Abortion and possible risk for breast cancer: analysis and inconsistencies. National Cancer Institute, Bethesda
    • (1994) National Cancer Institute, Bethesda
    • Anderson, L.1


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