Physics strategies for sparing neural stem cells during whole-brain radiation treatments

Medical Physics

Volumn 38, Issue 10, 2011, Pages 5338-5344

  Kirby, Neil ^a   Chuang, Cynthia ^a   Pouliot, Jean ^a   Hwang, Andrew ^a   Barani, Igor J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

collimator leakage; hippocampus; jaw motion; neural stem cells; whole brain radiotherapy

Indexed keywords

CYTOLOGY; RADIOTHERAPY;

HIPPOCAMPUS; INTENSITY-MODULATED RADIATION THERAPY; JAW MOTION; NEURAL STEM CELL; PREVENTIVE STRATEGIES; SEGMENTATION ALGORITHMS; WHOLE BRAIN RADIOTHERAPY; WHOLE-BRAIN RADIATION;

STEM CELLS;

PERU TOMATO MOSAIC VIRUS;

EID: 80053583306     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.3633946     Document Type: Article

References (28)

1. J. M. Butler, S. R. Rapp, and E. G. Shaw, Managing the cognitive effects of brain tumor radiation therapy., Curr. Treat. Options Oncol. 7, 517-523 (2006). 10.1007/s11864-006-0026-5 (Pubitemid 44697788)
2. O. K. Abayomi, Pathogenesis of irradiation-induced cognitive dysfunction., Acta Oncol. 35, 659-663 (1996). 10.3109/02841869609083995 (Pubitemid 26366721)
3. D. D. Roman and P. W. Sperduto, Neuropsychological effects of cranial radiation: current knowledge and future directions., Int. J. Radiat. Oncol. Biol. Phys. 31, 983-998 (1995). 10.1016/0360-3016(94)00550-8
4. C. A. Meyers and P. D. Brown, Role and relevance of neurocognitive assessment in clinical trials of patients with CNS tumors., J. Clin. Oncol. 24, 1305-1309 (2006). 10.1200/JCO.2005.04.6086 (Pubitemid 46622034)
5. I. J. Barani, L. W. Cuttino, S. H. Benedict, D. Todor, E. A. Bump, Y. Wu, T. D. Chung, W. C. Broaddus, and P. S. Lin, Neural stem cell-preserving external-beam radiotherapy of central nervous system malignancies., Int. J. Radiat. Oncol. Biol. Phys. 68, 978-985 (2007). 10.1016/j.ijrobp.2007.01.064 (Pubitemid 47048580)
6. J. M. Butler, L. D. Case, J. Atkins, B. Frizzell, G. Sanders, P. Griffin, G. Lesser, K. McMullen, R. McQuellon, M. Naughton, S. Rapp, V. Stieber, and E. G. Shaw, A phase III, double-blind, placebo-controlled prospective randomized clinical trial of d-threo-methylphenidate HCl in brain tumor patients receiving radiation therapy., Int. J. Radiat. Oncol. Biol. Phys. 69, 1496-1501 (2007). 10.1016/j.ijrobp.2007.05.076 (Pubitemid 350116415)
7. Y. Fan, Z. Liu, P. R. Weinstein, J. R. Fike, and J. Liu, Environmental enrichment enhances neurogenesis and improves functional outcome after cranial irradiation., Eur. J. Neurosci. 25, 38-46 (2007). 10.1111/j.1460-9568.2006. 05269.x (Pubitemid 46096221)
8. V. Gondi, R. Tolakanahalli, M. P. Mehta, D. Tewatia, H. Rowley, J. S. Kuo, D. Khuntia, and W. A. Tome, Hippocampal-sparing whole-brain radiotherapy: a how-to technique using helical tomotherapy and linear accelerator-based intensity-modulated radiotherapy., Int. J. Radiat. Oncol. Biol. Phys. 78, 1244-1252 (2010). 10.1016/j.ijrobp.2010.01.039
9. E. M. Yazlovitskaya, E. Edwards, D. Thotala, A. Fu, K. L. Osusky, W. O. Whetsell, B. Boone, E. T. Shinohara, and D. E. Hallahan, Lithium treatment prevents neurocognitive deficit resulting from cranial irradiation., Cancer Res. 66, 11179-11186 (2006). 10.1158/0008-5472.CAN-06-2740 (Pubitemid 46009945)
10. F. H. Gage, Mammalian neural stem cells., Science 287, 1433-1438 (2000). 10.1126/science.287.5457.1433 (Pubitemid 30127128)
11. S. Jessberger, F. H. Gage, Stem-cell-associated structural and functional plasticity in the aging hippocampus., Psychol. Aging 23, 684-691 (2008). 10.1037/a0014188
12. T. M. Madsen, P. E. G. Kristjansen, T. G. Bolwig, and G. Wortwein, Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat., Neuroscience 119, 635-642 (2003). 10.1016/S0306-4522(03)00199-4 (Pubitemid 36694791)
13. J. Raber, R. Rola, A. Lefevour, D. Morhardt, J. Curley, S. Mizumatsu, S. R. VandenBerg, and J. R. Fike, Radiation-induced cognitive impairments are associated with changes in indicators of hippocampal neurogenesis., Radiat. Res. 162, 39-47 (2004). 10.1667/RR3206 (Pubitemid 39044717)
14. R. Rola, J. Raber, A. Rizk, S. Otsuka, S. R. VandenBerg, D. R. Morhardt, and J. R. Fike, Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice., Exp. Neurol. 188, 316-330 (2004). 10.1016/j.expneurol.2004.05.005 (Pubitemid 38891593)
15. G. Winocur, J. M. Wojtowicz, M. Sekeres, J. S. Snyder, and S. Wang, Inhibition of neurogenesis interferes with hippocampus-dependent memory function., Hippocampus 16, 296-304 (2006). 10.1002/hipo.v16:3
16. J. R. Fike, R. Rola, and C. L. Limoli, Radiation response of neural precursor cells., Neurosurg. Clin. N. Am. 18, 115-127 (2007). 10.1016/j.nec.2006.10.010 (Pubitemid 46161195)
17. S. Mizumatsu, M. L. Monje, D. R. Morhardt, R. Rola, T. D. Palmer, and J. R. Fike, Extreme sensitivity of adult neurogenesis to low doses of X-irradiation., Cancer Res. 63, 4021-4027 (2003). (Pubitemid 36917922)
18. M. L. Monje, H. Vogel, M. Masek, K. L. Ligon, P. G. Fisher, and T. D. Palmer, Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies., Ann. Neurol. 62, 515-520 (2007). 10.1002/ana.21214 (Pubitemid 350308776)
19. R. Rola, K. Fishman, J. Baure, S. Rosi, K. R. Lamborn, A. Obenaus, G. A. Nelson, and J. R. Fike, Hippocampal neurogenesis and neuroinflammation after cranial irradiation with (56)Fe particles., Radiat. Res. 169, 626-632 (2008). 10.1667/RR1263.1 (Pubitemid 351793452)
20. M. L. Monje, S. Mizumatsu, J. R. Fike, and T. D. Palmer, Irradiation induces neural precursor-cell dysfunction., Nat. Med. 8, 955-962 (2002). 10.1038/nm749 (Pubitemid 35033699)
21. I. J. Barani, S. H. Benedict, and P. S. Lin, Neural stem cells: implications for the conventional radiotherapy of central nervous system malignancies., Int. J. Radiat. Oncol. Biol. Phys. 68, 324-333 (2007). 10.1016/j.ijrobp.2007.01.033 (Pubitemid 46694180)
22. J. C. Marsh, B. T. Gielda, A. M. Herskovic, J. A. Wendt, and J. V. Turian, Sparing of the hippocampus and limbic circuit during whole brain radiation therapy: a dosimetric study using helical tomotherapy., J. Med. Imaging Radiat. Oncol. 54, 375-382 (2010). 10.1111/j.1754-9485.2010.02184.x
23. J. C. Marsh, R. H. Godbole, A. M. Herskovic, B. T. Gielda, and J. V. Turian, Sparing of the neural stem cell compartment during whole-brain radiation therapy: a dosimetric study using helical tomotherapy., Int. J. Radiat. Oncol. Biol. Phys. 78, 946-954 (2010). 10.1016/j.ijrobp.2009.12.012
24. Z. Chang, Z. Wang, Q. J. Wu, H. Yan, J. Bowsher, J. Zhang, AND F. F. Yin, Dosimetric characteristics of Novalis Tx system with high definition multileaf collimator., Med. Phys. 35, 4460-4463 (2008). 10.1118/1.2977668
25. M. Tacke, S. Nill, P. Haring, and U. Oelfke, 6 MV dosimetric characterization of the 160 MLC, the new Siemens multileaf collimator., Med. Phys. 35, 1634-1642 (2008). 10.1118/1.2889782 (Pubitemid 351614777)
26. W. De Gersem, F. Claus, C. De Wagter, and W. De Neve, An anatomy-based beam segmentation tool for intensity-modulated radiation therapy and its application to head-and-neck cancer., Int. J. Radiat. Oncol. Biol. Phys. 51, 849-859 (2001). 10.1016/S0360-3016(01)02607-4 (Pubitemid 33116333)
27. D. M. Shepard, M. A. Earl, X. A. Li, S. Naqvi, and C. Yu, Direct aperture optimization: a turnkey solution for step-and-shoot IMRT., Med. Phys. 29, 1007-1018 (2002). 10.1118/1.1477415 (Pubitemid 34670528)
28. S. Webb, Direct aperture optimization for a variable aperture collimator for intensity-modulated radiation therapy., Phys. Med. Biol. 49, N47-55 (2004). 10.1088/0031-9155/49/5/N02 (Pubitemid 38344219)