Identification of 3-aminothieno[2,3-b]pyridine-2-carboxamides and 4-aminobenzothieno[3,2-d]pyrimidines as LIMK1 inhibitors

MedChemComm

Volumn 2, Issue 10, 2011, Pages 977-981

  Sleebs, Brad E ^a,b,c   Levit, Alla ^a,b,c   Street, Ian P ^a,b,c   Falk, Hendrik ^a,b,c   Hammonds, Tim ^d   Wong, Ai Ching ^d   Charles, Mark D ^d   Olson, Michael F ^e   Baell, Jonathan B ^a,b,c  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b Cancer Therapeutics CRC P/L   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d Cancer Research Technology Ltd   (United Kingdom)

^e BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINOTHIENO[2,3 B]PYRIDINE 2 CARBOXAMIDE DERIVATIVE; 4 AMINOBENZOTHIENO[3,2 D]PYRIMIDINE DERIVATIVE; LIM KINASE 1; THIENO[2,3 B]PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; IC 50; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 80053577178     PISSN: 20402503     EISSN: 20402511     Source Type: Journal    
DOI: 10.1039/c1md00137j     Document Type: Article

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