A quality by design (QbD) case study on liposomes containing hydrophilic API: I. Formulation, processing design and risk assessment

International Journal of Pharmaceutics

Volumn 419, Issue 1-2, 2011, Pages 52-59

  Xu, Xiaoming ^a   Khan, Mansoor A ^b   Burgess, Diane J ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Encapsulation efficiency; Liposome; Particle size; QbD; Risk analysis; Tenofovir

Indexed keywords

BUFFER; CHOLESTEROL; LIPID; LIPOSOME; TENOFOVIR;

ARTICLE; CONCENTRATION (PARAMETERS); DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SCREENING; ENCAPSULATION; FREEZE THAWING; HYDRATION; HYDROPHILICITY; PARTICLE SIZE; PELLET EXTRUSION; PRIORITY JOURNAL; QUALITY CONTROL; RISK ASSESSMENT; ULTRASOUND;

ADENINE; DELAYED-ACTION PREPARATIONS; DRUG DESIGN; FEASIBILITY STUDIES; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPIDS; LIPOSOMES; PARTICLE SIZE; PHOSPHONIC ACIDS; REVERSE TRANSCRIPTASE INHIBITORS; RISK ASSESSMENT;

EID: 80053568116     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.07.012     Document Type: Article

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