Reduced TH1/TH17 CD4 T-cell numbers are associated with impaired purified protein derivative-specific cytokine responses in patients with HIV-1 infection

Journal of Allergy and Clinical Immunology

Volumn 128, Issue 4, 2011, Pages

  Clark, Sally ^a   Page, Emma ^a,b   Ford, Tom ^a,c   Metcalf, Rebecca ^a   Pozniak, Anton ^b   Nelson, Mark ^b   Henderson, Donald C ^a,c   Asboe, David ^b   Gotch, Frances ^a   Gazzard, Brian G ^b   Kelleher, Peter ^a,b,c  

^a CHELSEA AND WESTMINSTER HOSPITAL   (United Kingdom)

^b CHELSEA AND WESTMINSTER HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

^c IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

Author keywords

CD4; HIV; IFN ; IL 2; Mycobacterium tuberculosis; tuberculosis

Indexed keywords

ANTIRETROVIRUS AGENT; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON; INTERLEUKIN 2; TUBERCULIN;

ADULT; ARTICLE; BCG VACCINATION; CD4 LYMPHOCYTE COUNT; CELL LOSS; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; CYTOKINE RELEASE; CYTOKINE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RISK FACTOR; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH17 CELL; TUBERCULOSIS;

EID: 80053562734     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.05.025     Document Type: Article

References (26)

1. TB/HIV Facts 2009. World Health Organisation. Available at: http://www.who.int/tb/challenges/hiv/factsheet-hivtb-2009update.pdf. Accessed October 3, 2010.
2. B.G. Williams, and C. Dye Antiretroviral drugs for tuberculosis control in the era of HIV/AIDS Science 301 2003 1535 1537 (Pubitemid 37128545)
3. P. Sonnenberg, J.R. Glynn, K. Fielding, J. Murray, P. Godfrey-Faussett, and S. Shearer How soon after infection with HIV does the risk of tuberculosis start to increase? A retrospective cohort study in South African gold miners J Infect Dis 191 2005 150 158 (Pubitemid 40096371)
4. B.E. Jones, S.M. Young, D. Antoniskis, P.T. Davidson, F. Kramer, and P.F. Barnes Relationship of the manifestations of tuberculosis to CD4 cell counts in patients with human immunodeficiency virus infection Am Rev Respir Dis 148 1993 1292 1297
5. S.H.E. Kaufmann, G. Hussey, and P.-H. Lambert New vaccines for tuberculosis Lancet 375 2010 2110 2119
6. E. Van de Vosse, J.T. van Dissel, and T.H. Ottenhoff Genetic deficiencies of innate immune signalling in human infectious disease Lancet Infect Dis 9 2009 688 698
7. C. Geldmacher, A. Schuetz, N. Ngwenyama, J.P. Casazza, E. Sanga, and E. Saathoff Early depletion of Mycobacterium tuberculosis-specific T helper cell responses after HIV-1 infection J Infect Dis 198 2008 1590 1598
8. M. Zhang, J. Gong, D.V. Iyer, B.E. Jones, R.L. Modlin, and P.F. Barnes T cell cytokine responses in persons with tuberculosis and human immunodeficiency virus infection J Clin Invest 94 1994 2435 2442 (Pubitemid 24379619)
9. R. Sutherland, H. Yang, T.J. Scriba, B. Ondondo, N. Robinson, and C. Conlon Impaired IFN-gamma secreting capacity in mycobacterial antigen-specific CD4 T cells during chronic HIV-1 infection despite long term HAART AIDS 20 2006 821 829 (Pubitemid 43731563)
10. L. Rivino, M. Messi, D. Jarrossay, A. Lanzavecchia, F. Sallusto, and J. Geginat Chemokine receptor expression identifies pre-T helper (Th1) pre-Th2 and non polarised among central memory CD4 T cells J Exp Med 200 2004 725 735 (Pubitemid 39299459)
11. E.V. Acosta-Rodriguez, L. Rivino, J. Geginat, D. Jarrossay, M. Gattorno, and A. Lanzavecchia Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells Nat Immunol 8 2007 639 646 (Pubitemid 46785128)
12. S. Trifari, C.D. Kaplan, E.H. Tran, N.K. Crellin, and H. Spits Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells Nat Immunol 10 2009 864 871
13. + T cells are highly permissive to HIV-1 infection J Immunol 184 2010 1604 1606
14. C. Geldmacher, N. Ngwenyama, A. Schuetz, C. Petrovas, K. Reither, and E.J. Heeregrave Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection J Exp Med 207 2010 2869 2881
15. C.Y. Kao, F. Huang, Y. Chen, P. Thai, S. Wachi, and C. Kim Up-regulation of CC chemokine ligand 20 expression in human airway epithelium by IL-17 through a JAK-independent but MEK/NF-κ B-dependent signalling pathway J Immunol 175 2005 6676 6685 (Pubitemid 41598911)
16. S.Y. Thomas, A. Banerji, B.D. Medoff, C. Lilly, and A.D. Luster Multiple chemokine receptors including CCR6 and CXCR3 regulate antigen induced T cell homing to the human asthmatic airway J Immunol 179 2007 1901 1912
17. M. Facco, I. Baesso, M. Miorin, M. Bortoli, A. Cabrelle, and E. Boscaro Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis J Leukoc Biol 82 2007 946 955 (Pubitemid 47511055)
18. M. Bofill, M. Lipman, J.E. McLaughlin, M.A. Johnson, and L.W. Poulter Changes in lung lymphocyte populations reflect those seen in peripheral blood in HIV-1 positive individuals Eur Respir J 11 1998 548 553 (Pubitemid 28194841)
19. B. Kalsdorf, T.J. Scriba, K. Wood, C.L. Day, K. Dheda, and R. Dawson HIV-1 infection impairs the bronchoalveolar T-cell response to mycobacteria Am J Respir Crit Care Med 2009 1262 1270
20. J.C. Jambo, E. Sepako, D.G. Fullerton, D. Mzinza, S. Glennie, and A.K. Wright Bronchoalveolar CD4+ T cell responses to respiratory antigens are impaired in HIV-infected adults Thorax 66 2011 375 382
21. K.S. Knox, C.S. Vinton, C.A. Hage, L.M. Kohli, and H.L. Twigg Reconstitution of CD4 T cells in BAL after initiation of highly active antiretroviral therapy J Virol 84 2010 9010 9018
22. B.L. Shacklett, and P. Anton HIV infection andgut mucosal immune function: updates on pathogenesis with implications for management and intervention Curr Infect Dis Rep 12 2010 19 27
23. C.R. Diedrich, J.T. Mattila, E. Klein, C. Janssen, J. Phuah, and T.J. Sturgeon Reactivation of latent tuberculosis in cynomologous macaques infected with SIV is associated with early peripheral T cell depletion and not viral load PLos One 5 2010 e9611
24. S.D. Lawn, L.-G. Bekker, and R. Wood How effectively does HAART restore immune responses to Mycobacterium tuberculosis? Implications for tuberculosis control AIDS 19 2005 1113 1124 (Pubitemid 41059253)
25. A.D. Harries, R. Zachariah, E.L. Corbett, S.D. Lawn, E.T. Santos-Filho, and R. Chimzizi The HIV-associated tuberculosis epidemic-when will we act Lancet 375 2010 1906 1919
26. J.P. Scott-Browne, S. Shafiani, G. Tucker-Heard, K. Ishida-Tsubota, J.D. Fontenot, and A.Y. Rudensky Expansion and function of FoxP3-expressing T regulatory cells during tuberculosis J Exp Med 204 2007 2159 2169 (Pubitemid 47360876)