CANCER CELL;
CARTILAGE CELL;
EPITHELIUM CELL;
HALF LIFE TIME;
HUMAN;
LETTER;
LEUKOCYTE;
NERVE CELL;
NONHUMAN;
PROTEIN BINDING;
PROTEIN DOMAIN;
PROTEIN EXPRESSION;
PROTEIN FUNCTION;
RECEPTOR BINDING;
REGULATORY T LYMPHOCYTE;
RHEUMATOID ARTHRITIS;
SIGNAL TRANSDUCTION;
Anti-TNF-α therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-β
Nadkarni S., et al. Anti-TNF-α therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-β. J. Exp. Med. 2007, 204:33-39.
The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice
Tang W., et al. The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science 2011, 332:478-484.
Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin
Kessenbrock K., et al. Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin. J. Clin. Invest. 2008, 118:2438-2447.
Poliovirus protein 3A inhibits tumor necrosis factor (TNF)-induced apoptosis by eliminating the TNF receptor from the cell surface
Neznanov N., et al. Poliovirus protein 3A inhibits tumor necrosis factor (TNF)-induced apoptosis by eliminating the TNF receptor from the cell surface. J. Virol. 2001, 75:10409-10420.
Variation in ligand binding specificities of a novel class of poxvirus-encoded tumor necrosis factor-binding protein
Rahman M.M., et al. Variation in ligand binding specificities of a novel class of poxvirus-encoded tumor necrosis factor-binding protein. J. Biol. Chem. 2006, 281:22517-22526.
Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors
Deng G.M., et al. Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors. Nat. Med. 2005, 11:1066-1072.
An endogenous TNF-α antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models
Graziewicz M.A., et al. An endogenous TNF-α antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models. Mol. Ther. 2008, 16:1316-1322.
MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-α during TLR4-induced gene reprogramming
El Gazzar, M. et al. (in press) MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-α during TLR4-induced gene reprogramming. J. Leukoc. Biol. Epub ahead of print.