An improved in vitro method for measuring skin permeability that controls excess hydration of skin using modified Franz diffusion cells

International Journal of Pharmaceutics

Volumn 419, Issue 1-2, 2011, Pages 96-106

  Levintova, Yuliya ^a   Plakogiannis, Fotios M ^a   Bellantone, Robert A ^a  

^a LONG ISLAND UNIVERSITY   (United States)

Author keywords

Human cadaver skin; In vitro; Modified Franz diffusion cells; Permeability; Pulsatile microdialysis; Skin breakdown

Indexed keywords

DOXEPIN;

ARTICLE; ARTIFICIAL MEMBRANE; CADAVER; CONTROLLED STUDY; DATA ANALYSIS; DIFFUSION; DRUG PENETRATION; EXPERIMENTAL DESIGN; GEL; HUMAN; HUMAN TISSUE; HYDRATION; IN VITRO STUDY; MALE; MATHEMATICAL MODEL; MICRODIALYSIS; PRIORITY JOURNAL; SKIN; SKIN PERMEABILITY;

DIFFUSION CHAMBERS, CULTURE; DOXEPIN; HUMANS; MALE; MEMBRANES, ARTIFICIAL; MICRODIALYSIS; MODELS, BIOLOGICAL; MODELS, THEORETICAL; PERMEABILITY; SKIN; SKIN ABSORPTION;

EID: 80053560666     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.07.025     Document Type: Article

References (14)

1. R. Bellantone, N. Nicolettos, and F. Plakogiannis Faster determination of the membrane permeability without using the lag time method Int. J. Pharm. 248 2001 81 92
2. R.L. Bronaugh, and H.I. Maibach In vitro Percutaneous Absorption: Principles, Fundamentals, and Applications 1991 CRC Press Florida
3. Brunner, M., Langer, O., 2006. Microdialysis versus other techniques for the clinical assessment of in vivo tissue drug distribution. AAPS J. 8 (2), Article 30 (http://www.aapsj.org).
4. K.C. Chen, M. Hoistad, J. Kehr, K. Fuxe, and C. Nicholson Theory relating in vitro and in vivo microdialysis with one or two probes J. Neurochem. 81 2002 108 121 (Pubitemid 34808858)
5. J. Crank The Mathematics of Diffusion 2nd ed. 1975 Oxford New York
6. W.I. Higuchi Analysis of data on the medicament release from ointments J. Pharm. Sci. 51 1962 802 804
7. K.A. Holbrook, and K. Wolff The Structure and Development of Skin 1993 McGraw-Hill New York
8. M.A. Kabir, D.R. Taft, C.K. Joseph, and R.A. Bellantone Measuring drug concentrations using pulsatile microdialysis: theory and method development in vitro Int. J. Pharm. 293 2005 171 182 (Pubitemid 40381091)
9. D.J. Mazzo, E.K.F. Fong, and S.E. Biffar A comparison of test methods for determining in vitro drug release from transdermal delivery dosage forms J. Pharm. Biomed. Anal. 4 1986 601 607 (Pubitemid 17198097)
10. Nicolettos, N., 1998. Transdermal Delivery of Certain Tricyclic Antidepressants: In vitro/in vivo Evaluations, Ph.D. Dissertation, Long Island University, Brooklyn, NY.
11. R.H. Queiroz Costa, V.L. Lanchote, P.S. Bonato, and D. de Carvalho Simultaneous HPLC analysis of tricyclic antidepressant and metabolites in plasma samples Pharm. Acta Helv. 70 1995 181 186
12. S. Sato, and S.W. Kim Macromolecular diffusion through polymer membranes Int. J. Pharm. 22 1984 229 255 (Pubitemid 15187774)
13. H. Schaefer, and T. Redelmeier Skin Barrier: Principles of Percutaneous Absorption 1996 Karger Basel
14. D.A. Van Hal, E. Jeremiasse, H.E. Junginger, F. Spies, and J.A. Bouwstra Structure of fully hydrated human stratum corneum: a freeze-fracture electron microscopy J. Invest. Dermatol. 106 1996 89 95 (Pubitemid 26052053)