L-alanyl-glutamine pretreatment attenuates acute inflammatory response in children submitted to palatoplasty;Pré-tratamento com l-alanil-glutamina atenua a resposta inflamatória aguda em crianças submetidas à palatoplastia

Acta Cirurgica Brasileira

Volumn 26, Issue SUPPL. 1, 2011, Pages 72-76

  da Cunha Filho, José Ferreira ^a   Gonçalves, Isabelle Ivo ^b   Guimarães, Sergio Botelho ^a   Jamacaru, Francisco Vagnaldo Fechine ^a   Garcia, José Huygens Parente ^a   de Vasconcelos, Paulo Roberto Leitão ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b UNIVERSITY OF FORTALEZA   (Brazil)

Author keywords

Congenital abnormalities. surgical procedures; Operative. glutamine. cytokines. child

Indexed keywords

ALANYLGLUTAMINE; C REACTIVE PROTEIN; GLUCOSE; GLUTATHIONE; INSULIN; INTERLEUKIN 6; PLACEBO; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; GLYCEMIC CONTROL; HUMAN; INFLAMMATION; MALE; OXIDATIVE STRESS; PALATOPLASTY; POSTOPERATIVE PERIOD; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; SINGLE BLIND PROCEDURE;

EID: 80053528204     PISSN: 01028650     EISSN: 16782674     Source Type: Journal    
DOI: 10.1590/s0102-86502011000700015     Document Type: Article

References (20)

1. Krost B, Schubert J. Influence of season on prevalence of cleft lip and palate. Int J Oral Maxillofac Surg. 2006;35:215-8.
2. Lenz A, Franklin GA, Cheadle WG Systemic inflammation after trauma. Injury. 2007;38(12):1336-45.
3. Lacey JM, Crouch JB, Benfell K, Ringer SA, Wilmore CK, Maguire D, Wilmore DW. The effects of glutamine-supplemented parenteral nutrition in premature infants. JPEN J Parenter Enteral Nutr. 1996;20(1):74-80.
4. Bergström J, Fürst P, Norée LO, Vinnars E. Intracellular free amino acid concentration in human muscle tissue. J Appl Physiol. 1974;36(6):693-7.
5. Wilmore DW. Metabolic response to severe surgical illness: overview. World J Surg. 2000;24(6):705-11.
6. DW. The effect of glutamine supplementation in patients following elective surgery and accidental injury. J Nutr. 2001;131(9 Suppl):2543S-9S; discussion 2550S-1S. Review.
7. Déchelotte P, Hasselmann M, Cynober L, Allaouchiche B, Coëffier M, Hecketsweiler B, Merle V, Mazerolles M, Samba D, Guillou YM, Petit J, Mansoor O, Colas G, Cohendy R, Barnoud D, Czernichow P, Bleichner G. L-alanyl-L-glutamine dipeptide-supplemented total parenteral nutrition reduces infectious complications and glucose intolerance in critically ill patients: the French controlled, randomized, double-blind, multicenter study. Crit Care Med. 2006;34(3):598-604.
8. Choudhary S, Cadier MA, Shinn DL, Shekhar K, McDowall RA. Effect of Veau-Wardill-Kilner type of cleft palate repair on long-term midfacial growth. Plast Reconstr Surg. 2003;111(2):576-82; discussion 583-5.
9. Sedlak J, Lindsay RH. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem. 1968;25(1):192-205.
10. Buege JA, Aust SD. Microsomal lipid peroxidation. Methods Enzymol. 1978;52:302-10.
11. Trinder P. Determination of blood glucose using 4-amino phenazone as oxygen acceptor. J Clin Pathol. 1969;22(2):246.
12. García-de-Lorenzo A, Zarazaga A, García-Luna PP, Gonzalez-Huix F, López-Martínez J, Miján A, Quecedo L, Casimiro C, Usán L, del Llano J. Clinical evidence for enteral nutritional support with glutamine: a systematic review. Nutrition. 2003;19(9):805-11.
13. Poindexter BB, Ehrenkranz RA, Stoll BJ, Koch MA, Wright LL, Oh W, Papile LA, Bauer CR, Carlo WA, Donovan EF, Fanaroff AA, Korones SB, Laptook AR, Shankaran S, Stevenson DK, Tyson JE, Lemons JA. Effect of parenteral glutamine supplementation on plasma amino acid concentrations in extremely low-birth-weight infants. Am J Clin Nutr. 2003;77(3):737-43.
14. Ward E, Smith M, Henderson M, Reid U, Lewis I, Kinsey S, Allgar V, Bowers D, Picton SV. The effect of high-dose enteral glutamine on the incidence and severity of mucositis in pediatric oncology patients. Eur J Clin Nutr. 2009; 63(1):134-40.
15. Jaye DL, Waites KB. Clinical applications of C-reactive protein in pediatrics. Pediatr Infect Dis J. 1997;16(8):735-46.
16. Black S, Kushner I, Samols D. C-reactive Protein. J Biol Chem. 2004;279(47):48487-90.
17. Ackland GL, Scollay JM, Parks RW, de Beaux I, Mythen MG. Pre-operative high sensitivity C-reactive protein and postoperative outcome in patients undergoing elective orthopaedic surgery. Anaesthesia. 2007;62(9):888-94.
18. Xing Z, Gauldie J, Cox G, Baumann H, Jordana M, Lei XF, Achong MK. IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses. J Clin Invest. 1998;101(2):311-20.
19. Lin E, Calvano SE, Lowry SF. Inflammatory cytokines and cell response in surgery. Surgery. 2000;127(2):117-26.
20. Lin MT, Kung SP, Yeh SL, Liaw KY, Wang MY, Kuo ML, Lee PH, Chen WJ. Glutamine-supplemented total parenteral nutrition attenuates plasma interleukin-6 in surgical patients with lower disease severity. World J Gastroenterol. 2005;11(39):6197-201.