Regression of early diabetic macular oedema is associated with prevention of dark adaptation

Eye

Volumn 25, Issue 12, 2011, Pages 1546-1554

  Arden, G B ^a   Jyothi, S ^b   Hogg, C H ^c   Lee, Y F ^b   Sivaprasad, S ^b  

^a CITY UNIVERSITY   (United Kingdom)

^b KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

^c MOORFIELDS EYE HOSPITAL   (United Kingdom)

Author keywords

adaptation; dark; diabetic macular oedema; hypoxia; lightmasks

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTRAST SENSITIVITY; CONTROLLED STUDY; DARK ADAPTATION; DIABETIC MACULAR EDEMA; DIABETIC RETINOPATHY; DISEASE ASSOCIATION; HUMAN; LIGHT ADAPTATION; OUTCOME ASSESSMENT; PATIENT SAFETY; RETINA IMAGE; RETINA ROD; SLEEP DISORDER; TREATMENT OUTCOME; VISUAL ACUITY;

EID: 80053526640     PISSN: 0950222X     EISSN: 14765454     Source Type: Journal    
DOI: 10.1038/eye.2011.264     Document Type: Article

References (38)

1. Mitchell P, Bandello F, Schmidt-Erfurth U, Lang GE, Massin P, Schlingemann RO, et al., RESTORE study group. The RESTORE study: ranibizumab monotherapy or combined with laser vs laser monotherapy for diabetic macular edema. Ophthalmology 2011; 118(4): 615-625.
2. Salam A, DaCosta J, Sivaprasad S. Anti-vascular endothelial growth factor agents for diabetic maculopathy. Br J Ophthalmol 2010; 94: 821-826.
3. Elman MJ, Aiello LP, Beck RW, Bressler NM, Bressler SB, Edwards AR, Diabetic Retinopathy Clinical Research Network et al. Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular oedema. Ophthalmology 2010; 117: 1064-1077.
4. Michaelides M, Kaines A, Hamilton RD, Fraser-Bell S, Rajendram R, Quhill F et al. A prospective randomized trial of intravitreal bevacizumab or laser therapy in the management of diabetic macular oedema (BOLT study) 12-month data: report 2. Ophthalmology 2010; 117: 1078-1086.
5. Azza El-Remessy M, Ali Behzadian A, Abou-Mohamed G, Franklin T, Caldwell RW, Caldwell RB. Experimental diabetes causes breakdown of the blood-retina barrier by a mechanism involving tyrosine nitration and increases in expression of vascular endothelial growth factor and urokinase plasminogen activator receptor. Am J Pathol 2003; 162: 1995-2004. (Pubitemid 36613056)
6. Braun RD, Linsenmeier RA, Goldstick TK. Oxygen consumption in the inner and outer retina of the cat. Invest Ophthalmol Vis Sci 1995; 36: 542-554.
7. Linsenmeier RA, Braun RD, McRipley MA, Padnick LB, Ahmed J, Hatchell DL et al. Retinal hypoxia in long-term diabetic cats. Invest Ophthalmol Vis Sci 1998; 39: 1647-1657. (Pubitemid 28361327)
8. Arden GB, Wolf JE, Collier J, Wolff C, Rosenberg M. Dark adaptation is impaired in diabetic before photopic loss can be seen. Can hypoxia contribute to diabetic retinopathy?. In: Hollyfield JG (ed). Retinal Degenerative Diseases and Experimental Therapy. Plenum Press: New York, 1999, pp 305-325.
9. Dean FM, Arden GB, Dornhorst A. Partial reversal of protan and tritan colour defects with inhaled oxygen in insulin dependent diabetic subjects. Br J Ophthalmol 1997; 81: 27-30. (Pubitemid 27068159)
10. Harris A, Arend O, Danis RP, Evans S, Wolf S, Martin BJ. Hyperoxia improves contrast sensitivity in early diabetic retinopathy. Br J Ophthalmol 1996; 80: 209-213. (Pubitemid 26090347)
11. Drasdo N, Chiti Z, Owens DR, North RV. Effect of darkness on inner retinal hypoxia in diabetes. Lancet 2002; 359(9325): 2251-2253. (Pubitemid 34717982)
12. Kern TS, Engerman RL. Capillary lesions develop in retina rather than cerebral cortex in diabetes and experimental galactosemia. Arch Ophthalmol 1996; 114: 306-310. (Pubitemid 26086737)
13. de Gooyer TE, Stevenson KA, Humphries P, Simpson DA, Gardiner TA, Stitt AW. Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration. Invest Ophthalmol Vis Sci 2006; 47: 5561-5568. (Pubitemid 46723810)
14. Arden GB, Wolf JE, Collier J, Wolff C, Rosenberg M. Dark adaptation is impaired in diabetics before photopic visual losses can be seen. Hollyfield et al. (eds). Retinal Degenerative Diseases and Experimental Therapy. Kluver Academic Plenum: New York, 1999, pp 305-316 Ch. 29.
15. Arden GB. The absence of diabetic retinopathy in patients with retinitis pigmentosa: implications for pathophysiology and possible treatment. Brit J Ophthalmol 2001; 85: 366-370. (Pubitemid 32250774)
16. Nguyen QD, Shah SM, Van Anden E, Sung JU, Vitale S, Campochiaro PA. Supplemental oxygen improves diabetic macular oedema: a pilot study. Invest Ophthalmol Vis Sci 2004; 45: 617-624. (Pubitemid 38140522)
17. Shiba T, Sato Y, Takahashi M. Relationship between diabetic retinopathy and sleep-disordered breathing. Am J Ophthalmol 2009; 147: 1017-1021.
18. West SD, Groves DC, Lipinski HJ, Nicoll DJ, Mason RH, Scanlon PH et al. The prevalence of retinopathy in men with Type 2 diabetes and obstructive sleep apnoea. Diabet Med 2010; 27: 423-430.
19. Busik JV, Mohr S, Grant MB. Hyperglycaemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediators. Diabetes 2008; 57: 1952-1965.
20. Arden GB, Wolf JE, Tsang Y. Does dark adaptation exacerbate diabetic retinopathy? Evidence and a linking hypothesis. Vision Res 1998; 38: 1723-1729. (Pubitemid 28302165)
21. Arden GB, Sidman RL, Arap W, Schlingemann RO. Spare the rod and spoil the eye. Br J Ophthalmol 2005; 89: 764-769. (Pubitemid 40780588)
22. Arden GB. Comments on 'A new view of diabetic Retinopathy' by AJ Barber. Prog Neuropsychopharmacol Biol Psychiatry 2004; 28: 747-748.
23. Hagins WA, Ross PD, Tate RL, Yoshikami S. Transduction heats in retinal rods: tests of the role of cGMP by pyroelectric calorimetry. Proc Natl Acad Sci USA 1998; 86: 1224-1228.
24. Hamer RD, Nicholas SC, Tranchina D, Lamb TD, Jarvinen JL. Toward a unified model of vertebrate rod phototransduction. Vis Neurosci 2005; 22: 417-436. (Pubitemid 43237767)
25. Birol G, Wang S, Budzynski E, Wangsa-Wirawan ND, Linsenmeier RA. Oxygen distribution and consumption in the macaque retina. Am J Physiol Heart Circ Physiol 2007; 293: H1696-H1704. (Pubitemid 47367217)
26. Arden GB, Gündüz MK, Kurtenbach A, Völker M, Zrenner E, Gündüz SB et al. Preliminary trial to determine whether prevention of dark adaptation affects the course of early diabetic retinopathy. Eye 2010; 24: 1149-1155.
27. Reznicek L, Kernt M, Haritoglou C, Kampik A, Ulbig M, Neubauer AS. In vivo characterization of ischemic retina in diabetic retinopathy. Clin Ophthalmol 2011; 5: 31-35.
28. Sliney DH, Wolbarsht ML. Safety with Lasers and Other Optical Sources. Plenum Press: New York, 1980.
29. Robinson J, Bayliss S, Fielder AR. Transmission of light across the adult and neonatal eyelid in vivo. Vision Res 1991; 31: 1837-1840.
30. Berson DM, Dunn FA, Takao M. Phototransduction by retinal ganglion cells that set the circadian clock. Science 2002; 295: 1070-1073. (Pubitemid 34132236)
31. Stevens RG. Electric light causes cancer? Surely you're joking, Mr. Stevens. Mutat Res 2009; 682: 1-6.
32. Brainard GC, Hanifin JP, Greeson JM, Byrne B, Glickman G, Gerner E et al. Action spectrum for melatonin regulation in humans: evidence for a novel circadian photoreceptor. J Neurosci 2001; 21: 6405-6412. (Pubitemid 32737772)
33. Thapan, Arendt J, Skene DJ. An action spectrum for melatonin suppression: evidence for a novel non-rod, non-cone photoreceptor system in humans. J Physiol 2001; 535: 261-267. (Pubitemid 32782742)
34. Young RW. The renewal of rod and cone outer segments in the rhesus monkey. J Cell Biol 1971; 49: 313-318.
35. Schremser JL, Williams TP. Rod outer segment (ROS) renewal as a mechanism for adaptation to a new intensity environment. I. Rhodopsin levels and ROS length. Exp Eye Res 1995; 61: 17-23.
36. Williams TP, Henrich S, Reiser M. Effect of eye closures and openings on photostasis in albino rats. Invest Ophthalmol Vis Sci 1998; 39: 603-609. (Pubitemid 28110694)
37. Williams TP, Webbers JP, Giordano L, Henderson RP. Distribution of photon absorption rates across the rat retina. J Physiol 1998; 508: 515-522. (Pubitemid 28203965)
38. Williams TP, Squitieri A, Henderson RP, Webbers JP. Reciprocity between light intensity and rhodopsin concentration across the rat retina. J Physiol 1999; 516: 869-874. (Pubitemid 29201909)