Differential expression of up-regulated cofilin-1 and down-regulated cofilin-2 characteristic of pancreatic cancer tissues

Oncology Reports

Volumn 26, Issue 6, 2011, Pages 1595-1599

  Wang, Yufeng ^a   Kuramitsu, Yasuhiro ^a   Ueno, Tomio ^a   Suzuki, Nobuaki ^a   Yoshino, Shigefumi ^a   Iizuka, Norio ^a   Zhang, Xiulian ^a   Oka, Masaaki ^a   Nakamura, Kazuyuki ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cofilin 1 2; Liquid chromatography tandem mass spectrometry; Pancreatic cancer; Two dimensional gel electrophoresis

Indexed keywords

BIOLOGICAL MARKER; COFILIN 1; COFILIN 2; ISOPROTEIN;

ARTICLE; CANCER GROWTH; CANCER TISSUE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN TISSUE; LIQUID CHROMATOGRAPHY; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; COFILIN 1; COFILIN 2; DOWN-REGULATION; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE EXPRESSION; HUMANS; MOLECULAR SEQUENCE DATA; PANCREATIC NEOPLASMS; PROTEIN ISOFORMS; TANDEM MASS SPECTROMETRY; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 80053519535     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1447     Document Type: Article

References (29)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J and Thun MJ: Cancer statistics, 2009. CA Cancer J Clin 59: 225-249, 2009.
2. Kuramitsu Y, Miyamoto H, Tanaka T, Zhang X, Fujimoto M, Ueda K, Tanaka T, Hamano K and Nakamura K: Proteomic differential display analysis identified upregulated astrocytic phosphoprotein PEA-15 in human malignant pleural mesothelioma cell lines. Proteomics 9: 5078-5089, 2009.
3. Luk JM, Lam CT, Siu AF, Lam BY, Ng IO, Hu MY, Che CM and Fan ST: Proteomic profiling of hepatocellular carcinoma in Chinese cohort reveals heat-shock protein (Hsp27, Hsp70, GRP78) up-regulation and their associated prognostic values. Proteomics 6: 1049-1057, 2006.
4. Roth U, Razawi H, Hommer J, Engelmann K, Schwientek T, Müller S, Baldus SE, Patsos G, Corfield AP, Paraskeva C and Hanisch FG: Differential expression proteomics of human colorectal cancer based on a syngeneic cellular model for the progression of adenoma to carcinoma. Proteomics 10: 194-202, 2010.
5. Kuramitsu Y, Harada T, Takashima M, Yokoyama Y, Hidaka I, Iizuka N, Toda T, Fujimoto M, Zhang X, Sakaida I, Okita K, Oka M and Nakamura K: Increased expression and phosphorylation of liver glutamine synthetase in well-differentiated hepatocellular carcinoma tissues from patients infected with hepatitis C virus. Electrophoresis 27: 1651-1658, 2006.
6. Wang Y, Kuramitsu Y, Yoshino S, Takashima M, Zhang X, Ueno T, Suzuki N, Oka M and Nakamura K: Screening for serological biomarkers of pancreatic cancer by two-dimensional electrophoresis and liquid chromatography-tandem mass spectrometry. Oncol Rep 26: 287-292, 2011.
7. Tanaka T, Kuramitsu Y, Fujimoto M, Naito S, Oka M and Nakamura K: Downregulation of two isoforms of ubiquitin carboxyl-terminal hydrolase isozyme L1 correlates with high metastatic potentials of human SN12C renal cell carcinoma cell clones. Electrophoresis 29: 2651-2659, 2008.
8. Kuramitsu Y, Hayashi E, Okada F, Tanaka T, Zhang X, Ueyama Y and Nakamura K: Proteomic analysis for nuclear proteins related to tumour malignant progression: a comparative proteomic study between malignant progressive cells and regressive cells. Anticancer Res 30: 2093-2099, 2010.
9. Kuramitsu Y, Baron B, Yoshino S, Zhang X, Tanaka T, Yashiro M, Hirakawa K, Oka M and Nakamura K: Proteomic differential display analysis shows up-regulation of 14-3-3 protein sigma in human scirrhous-type gastric carcinoma cells. Anticancer Res 30: 4459-4465, 2010.
10. Kuramitsu Y, Taba K, Ryozawa S, Yoshida K, Tanaka T, Zhang X, Maehara S, Maehara Y, Sakaida I and Nakamura K: Identification of up- and down-regulated proteins in gemcitabine-resistant pancreatic cancer cells using two-dimensional gel electrophoresis and mass spectrometry. Anticancer Res 30: 3367-3372, 2010.
11. Kuramitsu Y, Hayashi E, Okada F, Zhang X, Tanaka T, Ueyama Y and Nakamura K: Staining with highly sensitive Coomassie brilliant blue SeePico™ stain after Flamingo™ fluorescent gel stain is useful for cancer proteomic analysis by means of two-dimensional gel electrophoresis. Anticancer Res 30: 4001-4005, 2010.
12. Mori-Iwamoto S, Kuramitsu Y, Ryozawa S, Mikuria K, Fujimoto M, Maehara S, Maehara Y, Okita K, Nakamura K and Sakaida I: Proteomics finding heat shock protein 27 as a biomarker for resistance of pancreatic cancer cells to gemcitabine. Int J Oncol 31: 1345-1350, 2007.
13. Yamaguchi H and Condeelis J: Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta 1773: 642-652, 2007.
14. Wang W, Mouneimne G, Sidani M, Wyckoff J, Chen X, Makris A, Goswami S, Bresnick AR and Condeelis JS: The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors. J Cell Biol 173: 395-404, 2006.
15. Delorme V, Machacek M, DerMardirossian C, Anderson KL, Wittmann T, Hanein D, Waterman-Storer C, Danuser G and Bokoch GM: Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks. Dev Cell 13: 646-662, 2007.
16. Van Rheenen J, Song X, Van Roosmalen W, Cammer M, Chen X, Desmarais V, Yip SC, Backer JM, Eddy RJ and Condeelis JS: EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells. J Cell Biol 179: 1247-1259, 2007.
17. Bamburg JR: Proteins of the ADF/cofilin family: essential regulators of actin dynamics. Annu Rev Cell Dev Biol 15: 185-230, 1999.
18. Aizawa H, Sutoh K, Tsubuki S, Kawashima S, Ishii A and Yahara I: Identification, characterization, and intracellular distribution of cofilin in Dictyostelium discoideum. J Biol Chem 270: 10923-10932, 1995.
19. Aizawa H, Sutoh K and Yahara I: Overexpression of cofilin stimulates bundling of actin filaments, membrane ruffling, and cell movement in Dictyostelium. J Cell Biol 132: 335-344, 1996.
20. Hotulainen P, Paunola E, Vartiainen MK and Lappalainen P: Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells. Mol Biol Cell 16: 649-664, 2005.
21. Wang W, Goswami S, Lapidus K, Wells AL, Wyckoff JB, Sahai E, Singer RH, Segall JE and Condeelis JS: Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors. Cancer Res 64: 8585-8594, 2004.
22. Yap CT, Simpson TI, Pratt T, Price DJ and Maciver SK: The motility of glioblastoma tumour cells is modulated by intracellular cofilin expression in a concentration-dependent manner. Cell Motil Cytoskeleton 60: 153-165, 2005.
23. Gunnersen JM, Spirkoska V, Smith PE, Danks RA and Tan SS: Growth and migration markers of rat C6 glioma cells identified by serial analysis of gene expression. Glia 32: 146-154, 2000.
24. Vartiainen MK, Mustonen T, Mattila PK, Ojala PJ, Thesleff I, Partanen J and Lappalainen P: The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics. Mol Biol Cell 13: 183-194, 2002.
25. Aizawa H, Kishi Y, Iida K, Sameshima M and Yahara I: Cofilin-2, a novel type of cofilin, is expressed specifically at aggregation stage of Dictyostelium discoideum development. Genes Cells 6: 913-921, 2001.
26. Thirion C, Stucka R, Mendel B, Gruhler A, Jaksch M, Nowak KJ, Binz N, Laing NG and Lochmüller H: Characterization of human muscle type cofilin (CFL2) in normal and regenerating muscle. Eur J Biochem 268: 3473-3482, 2001.
27. Codogno P: Autophagy in cell survival and death. J Soc Biol 199: 233-241, 2005.
28. Sinha P, Hütter G, Köttgen E, Dietel M, Schadendorf D and Lage H: Increased expression of epidermal fatty acid binding protein, cofilin, and 14-3-3-sigma (stratifin) detected by two-dimensional gel electrophoresis, mass spectrometry and microsequencing of drug-resistant human adenocarcinoma of the pancreas. Electrophoresis 20: 2952-2960, 1999.
29. Cecconi D, Astner H, Donadelli M, Palmieri M, Missiaglia E, Hamdan M, Scarpa A and Righetti PG: Proteomic analysis of pancreatic ductal carcinoma cells treated with 5-aza-2′-deoxycytidine. Electrophoresis 24: 4291-4303, 2003.