-
1
-
-
77954924659
-
Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma
-
Stupp R, Hegi ME, Neyns B, et al. Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma. J Clin Oncol 2010; 28: 2712-8.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2712-2718
-
-
Stupp, R.1
Hegi, M.E.2
Neyns, B.3
-
2
-
-
0042856667
-
Using mice to decipher the molecular genetics of brain tumors
-
discussion 695
-
Hesselager G, Holland EC. Using mice to decipher the molecular genetics of brain tumors. Neurosurgery 2003; 53: 685-94; discussion 695.
-
(2003)
Neurosurgery
, vol.53
, pp. 685-694
-
-
Hesselager, G.1
Holland, E.C.2
-
3
-
-
70849122697
-
Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations
-
Brennan C, Momota H, Hambardzumyan D, et al. Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations. PLoS One 2009; 4: e7752.
-
(2009)
PLoS One
, vol.4
-
-
Brennan, C.1
Momota, H.2
Hambardzumyan, D.3
-
6
-
-
34249332411
-
CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles
-
Beier D, Hau P, Proescholdt M, et al. CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res 2007; 67: 4010-5.
-
(2007)
Cancer Res
, vol.67
, pp. 4010-4015
-
-
Beier, D.1
Hau, P.2
Proescholdt, M.3
-
7
-
-
67649939163
-
The increasing complexity of the cancer stem cell paradigm
-
Rosen JM, Jordan CT. The increasing complexity of the cancer stem cell paradigm. Science 2009; 324: 1670-3.
-
(2009)
Science
, vol.324
, pp. 1670-1673
-
-
Rosen, J.M.1
Jordan, C.T.2
-
8
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S, Wu Q, McLendon RE, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006; 444: 756-60.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
-
9
-
-
33845671339
-
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
-
Liu G, Yuan X, Zeng Z, et al. Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Mol Cancer 2006; 5: 67.
-
(2006)
Mol Cancer
, vol.5
, pp. 67
-
-
Liu, G.1
Yuan, X.2
Zeng, Z.3
-
10
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
Calabrese C, Poppleton H, Kocak M, et al. A perivascular niche for brain tumor stem cells. Cancer Cell 2007; 11: 69-82.
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
-
11
-
-
65749106405
-
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
-
Li Z, Bao S, Wu Q, et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 2009; 15: 501-13.
-
(2009)
Cancer Cell
, vol.15
, pp. 501-513
-
-
Li, Z.1
Bao, S.2
Wu, Q.3
-
13
-
-
70350225829
-
The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
-
Heddleston JM, Li Z, McLendon RE, Hjelmeland AB, Rich JN. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle 2009; 8.
-
(2009)
Cell Cycle
, pp. 8
-
-
Heddleston, J.M.1
Li, Z.2
McLendon, R.E.3
Hjelmeland, A.B.4
Rich, J.N.5
-
14
-
-
70449687092
-
Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha
-
Soeda A, Park M, Lee D, et al. Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha. Oncogene 2009; 28: 3949-59.
-
(2009)
Oncogene
, vol.28
, pp. 3949-3959
-
-
Soeda, A.1
Park, M.2
Lee, D.3
-
15
-
-
77950838848
-
A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha
-
Seidel S, Garvalov BK, Wirta V, et al. A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha. Brain: a journal of neurology 2010; 133: 983-95.
-
(2010)
Brain: A Journal of Neurology
, vol.133
, pp. 983-995
-
-
Seidel, S.1
Garvalov, B.K.2
Wirta, V.3
-
17
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
Lapidot T, Sirard C, Vormoor J, et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 1994; 367: 645-8.
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
-
18
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997; 3: 730-7.
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
19
-
-
70349479538
-
Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment
-
Bertolini G, Roz L, Perego P, et al. Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment. Proc Natl Acad Sci U S A 2009; 106: 16281-6.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 16281-16286
-
-
Bertolini, G.1
Roz, L.2
Perego, P.3
-
20
-
-
73349125059
-
CD133 expression defines a tumor initiating cell population in primary human ovarian cancer
-
Curley MD, Therrien VA, Cummings CL, et al. CD133 expression defines a tumor initiating cell population in primary human ovarian cancer. Stem Cells 2009; 27: 2875-83.
-
(2009)
Stem Cells
, vol.27
, pp. 2875-2883
-
-
Curley, M.D.1
Therrien, V.A.2
Cummings, C.L.3
-
21
-
-
27144557960
-
A tumorigenic subpopulation with stem cell properties in melanomas
-
Fang D, Nguyen TK, Leishear K, et al. A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res 2005; 65: 9328-37.
-
(2005)
Cancer Res
, vol.65
, pp. 9328-9337
-
-
Fang, D.1
Nguyen, T.K.2
Leishear, K.3
-
22
-
-
77950863856
-
Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery
-
Fang DD, Kim YJ, Lee CN, et al. Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery. Br J Cancer 2010; 102: 1265-75.
-
(2010)
Br J Cancer
, vol.102
, pp. 1265-1275
-
-
Fang, D.D.1
Kim, Y.J.2
Lee, C.N.3
-
23
-
-
51649099207
-
CD133+CD44+ population efficiently enriches colon cancer initiating cells
-
Haraguchi N, Ohkuma M, Sakashita H, et al. CD133+CD44+ population efficiently enriches colon cancer initiating cells. Ann Surg Oncol 2008; 15: 2927-33.
-
(2008)
Ann Surg Oncol
, vol.15
, pp. 2927-2933
-
-
Haraguchi, N.1
Ohkuma, M.2
Sakashita, H.3
-
24
-
-
75149165632
-
Characterization of melanoma cells capable of propagating tumors from a single cell
-
Held MA, Curley DP, Dankort D, McMahon M, Muthusamy V, Bosenberg MW. Characterization of melanoma cells capable of propagating tumors from a single cell. Cancer Res 2010; 70: 388-97.
-
(2010)
Cancer Res
, vol.70
, pp. 388-397
-
-
Held, M.A.1
Curley, D.P.2
Dankort, D.3
McMahon, M.4
Muthusamy, V.5
Bosenberg, M.W.6
-
25
-
-
77950862035
-
Ovarian cancer stem-like sidepopulation cells are tumourigenic and chemoresistant
-
Hu L, McArthur C, Jaffe RB. Ovarian cancer stem-like sidepopulation cells are tumourigenic and chemoresistant. Br J Cancer 2010; 102: 1276-83.
-
(2010)
Br J Cancer
, vol.102
, pp. 1276-1283
-
-
Hu, L.1
McArthur, C.2
Jaffe, R.B.3
-
26
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007; 445: 106-10.
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
27
-
-
65249182549
-
Isolation and characterization of CD133+ cell population within human primary and metastatic colon cancer
-
Puglisi MA, Sgambato A, Saulnier N, et al. Isolation and characterization of CD133+ cell population within human primary and metastatic colon cancer. Eur Rev Med Pharmacol Sci 2009; 13 Suppl 1: 55-62.
-
(2009)
Eur Rev Med Pharmacol Sci
, vol.13
, Issue.13 SUPPL. 1
, pp. 55-62
-
-
Puglisi, M.A.1
Sgambato, A.2
Saulnier, N.3
-
28
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E, et al. Identification and expansion of human colon-cancer-initiating cells. Nature 2007; 445: 111-5.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
-
29
-
-
68749092099
-
The role of CD133 in the identification and characterisation of tumour-initiating cells in nonsmall- cell lung cancer
-
Tirino V, Camerlingo R, Franco R, et al. The role of CD133 in the identification and characterisation of tumour-initiating cells in nonsmall- cell lung cancer. Eur J Cardiothorac Surg 2009; 36: 446-53.
-
(2009)
Eur J Cardiothorac Surg
, vol.36
, pp. 446-453
-
-
Tirino, V.1
Camerlingo, R.2
Franco, R.3
-
30
-
-
54949122514
-
Detection and characterization of CD133+ cancer stem cells in human solid tumours
-
Tirino V, Desiderio V, d'Aquino R, et al. Detection and characterization of CD133+ cancer stem cells in human solid tumours. PLoS One 2008; 3: e3469.
-
(2008)
PLoS One
, vol.3
-
-
Tirino, V.1
Desiderio, V.2
d'Aquino, R.3
-
31
-
-
79957883579
-
Human primary bone sarcomas contain CD133+ cancer stem cells displaying high tumorigenicity in vivo
-
Tirino V, Desiderio V, Paino F, et al. Human primary bone sarcomas contain CD133+ cancer stem cells displaying high tumorigenicity in vivo. FASEB J 2011.
-
(2011)
FASEB J
-
-
Tirino, V.1
Desiderio, V.2
Paino, F.3
-
32
-
-
77951180207
-
Isolation and characterization of hepatic cancer cells with stem-like properties from hepatocellular carcinoma
-
Tomuleasa C, Soritau O, Rus-Ciuca D, et al. Isolation and characterization of hepatic cancer cells with stem-like properties from hepatocellular carcinoma. J Gastrointestin Liver Dis 2010; 19: 61-7.
-
(2010)
J Gastrointestin Liver Dis
, vol.19
, pp. 61-67
-
-
Tomuleasa, C.1
Soritau, O.2
Rus-Ciuca, D.3
-
33
-
-
34248529666
-
Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line
-
Wang J, Guo LP, Chen LZ, Zeng YX, Lu SH. Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line. Cancer Res 2007; 67: 3716-24.
-
(2007)
Cancer Res
, vol.67
, pp. 3716-3724
-
-
Wang, J.1
Guo, L.P.2
Chen, L.Z.3
Zeng, Y.X.4
Lu, S.H.5
-
34
-
-
42549142322
-
Brca1 breast tumors contain distinct CD44+/CD24- and CD133+ cells with cancer stem cell characteristics
-
Wright MH, Calcagno AM, Salcido CD, Carlson MD, Ambudkar SV, Varticovski L. Brca1 breast tumors contain distinct CD44+/CD24- and CD133+ cells with cancer stem cell characteristics. Breast Cancer Res 2008; 10: R10.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Wright, M.H.1
Calcagno, A.M.2
Salcido, C.D.3
Carlson, M.D.4
Ambudkar, S.V.5
Varticovski, L.6
-
35
-
-
77949891635
-
Cancer stem/progenitor cells are highly enriched in CD133+CD44+ population in hepatocellular carcinoma
-
Zhu Z, Hao X, Yan M, et al. Cancer stem/progenitor cells are highly enriched in CD133+CD44+ population in hepatocellular carcinoma. Int J Cancer 2010; 126: 2067-78.
-
(2010)
Int J Cancer
, vol.126
, pp. 2067-2078
-
-
Zhu, Z.1
Hao, X.2
Yan, M.3
-
36
-
-
77954238710
-
Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
-
Boiko AD, Razorenova OV, van de Rijn M, et al. Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature 2010; 466: 133-7.
-
(2010)
Nature
, vol.466
, pp. 133-137
-
-
Boiko, A.D.1
Razorenova, O.V.2
van de Rijn, M.3
-
37
-
-
74049159468
-
Identification of tumor stem-like cells in a mouse myeloma cell line
-
Dou J, Li Y, Zhao F, et al. Identification of tumor stem-like cells in a mouse myeloma cell line. Cell Mol Biol (Noisy-le-grand) 2009; 55 Suppl: OL1151-60.
-
(2009)
Cell Mol Biol (Noisy-le-grand)
, vol.55
, Issue.SUPPL.
-
-
Dou, J.1
Li, Y.2
Zhao, F.3
-
38
-
-
57349143739
-
Efficient tumour formation by single human melanoma cells
-
Quintana E, Shackleton M, Sabel MS, Fullen DR, Johnson TM, Morrison SJ. Efficient tumour formation by single human melanoma cells. Nature 2008; 456: 593-8.
-
(2008)
Nature
, vol.456
, pp. 593-598
-
-
Quintana, E.1
Shackleton, M.2
Sabel, M.S.3
Fullen, D.R.4
Johnson, T.M.5
Morrison, S.J.6
-
39
-
-
0344735881
-
Cancerous stem cells can arise from pediatric brain tumors
-
Hemmati HD, Nakano I, Lazareff JA, et al. Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci U S A 2003; 100: 15178-83.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15178-15183
-
-
Hemmati, H.D.1
Nakano, I.2
Lazareff, J.A.3
-
40
-
-
38349165576
-
Identification of cells initiating human melanomas
-
Schatton T, Murphy GF, Frank NY, et al. Identification of cells initiating human melanomas. Nature 2008; 451: 345-9.
-
(2008)
Nature
, vol.451
, pp. 345-349
-
-
Schatton, T.1
Murphy, G.F.2
Frank, N.Y.3
-
41
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh SK, Clarke ID, Terasaki M, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res 2003; 63: 5821-8.
-
(2003)
Cancer Res
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
-
42
-
-
33750313208
-
Cancer stem cells-- perspectives on current status and future directions: AACR Workshop on cancer stem cells
-
Clarke MF, Dick JE, Dirks PB, et al. Cancer stem cells-- perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res 2006; 66: 9339-44.
-
(2006)
Cancer Res
, vol.66
, pp. 9339-9344
-
-
Clarke, M.F.1
Dick, J.E.2
Dirks, P.B.3
-
43
-
-
65749087298
-
Neurosphere formation is an independent predictor of clinical outcome in malignant glioma
-
Laks DR, Masterman-Smith M, Visnyei K, et al. Neurosphere formation is an independent predictor of clinical outcome in malignant glioma. Stem Cells 2009; 27: 980-7.
-
(2009)
Stem Cells
, vol.27
, pp. 980-987
-
-
Laks, D.R.1
Masterman-Smith, M.2
Visnyei, K.3
-
44
-
-
77955158299
-
The utility and limitations of neurosphere assay, CD133 immunophenotyping and side population assay in glioma stem cell research
-
Wan F, Zhang S, Xie R, Gao B, Campos B, Herold-Mende C, Lei T. The utility and limitations of neurosphere assay, CD133 immunophenotyping and side population assay in glioma stem cell research. Brain Pathol 2010; 20: 877-89.
-
(2010)
Brain Pathol
, vol.20
, pp. 877-889
-
-
Wan, F.1
Zhang, S.2
Xie, R.3
Gao, B.4
Campos, B.5
Herold-Mende, C.6
Lei, T.7
-
45
-
-
33646358694
-
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serumcultured cell lines
-
Lee J, Kotliarova S, Kotliarov Y, et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serumcultured cell lines. Cancer Cell 2006; 9: 391-403.
-
(2006)
Cancer Cell
, vol.9
, pp. 391-403
-
-
Lee, J.1
Kotliarova, S.2
Kotliarov, Y.3
-
46
-
-
0033015699
-
Basic fibroblast growth factor promotes epidermal growth factor responsiveness and survival of mesencephalic neural precursor cells
-
Santa-Olalla J, Covarrubias L. Basic fibroblast growth factor promotes epidermal growth factor responsiveness and survival of mesencephalic neural precursor cells. J Neurobiol 1999; 40: 14-27.
-
(1999)
J Neurobiol
, vol.40
, pp. 14-27
-
-
Santa-Olalla, J.1
Covarrubias, L.2
-
47
-
-
0027491410
-
bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells
-
Vescovi AL, Reynolds BA, Fraser DD, Weiss S. bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells. Neuron 1993; 11: 951-66.
-
(1993)
Neuron
, vol.11
, pp. 951-966
-
-
Vescovi, A.L.1
Reynolds, B.A.2
Fraser, D.D.3
Weiss, S.4
-
48
-
-
0034008662
-
Establishment and properties of a growth factor-dependent, perpetual neural stem cell line from the human CNS
-
Villa A, Snyder EY, Vescovi A, Martinez-Serrano A. Establishment and properties of a growth factor-dependent, perpetual neural stem cell line from the human CNS. Exp Neurol 2000; 161: 67-84.
-
(2000)
Exp Neurol
, vol.161
, pp. 67-84
-
-
Villa, A.1
Snyder, E.Y.2
Vescovi, A.3
Martinez-Serrano, A.4
-
49
-
-
69249139924
-
Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogens
-
Kelly JJ, Stechishin O, Chojnacki A, et al. Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogens. Stem Cells 2009; 27: 1722-33.
-
(2009)
Stem Cells
, vol.27
, pp. 1722-1733
-
-
Kelly, J.J.1
Stechishin, O.2
Chojnacki, A.3
-
50
-
-
33748051406
-
Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
-
Bao S, Wu Q, Sathornsumetee S, et al. Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res 2006; 66: 7843-8.
-
(2006)
Cancer Res
, vol.66
, pp. 7843-7848
-
-
Bao, S.1
Wu, Q.2
Sathornsumetee, S.3
-
51
-
-
70350223977
-
Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth
-
Wang H, Lathia JD, Wu Q, et al. Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth. Stem Cells 2009.
-
(2009)
Stem Cells
-
-
Wang, H.1
Lathia, J.D.2
Wu, Q.3
-
52
-
-
77955821735
-
Molecular analysis of ex-vivo CD133+ GBM cells revealed a common invasive and angiogenic profile but different proliferative signatures among high grade gliomas
-
Garcia JL, Perez-Caro M, Gomez-Moreta JA, et al. Molecular analysis of ex-vivo CD133+ GBM cells revealed a common invasive and angiogenic profile but different proliferative signatures among high grade gliomas. BMC Cancer 2010; 10: 454.
-
(2010)
BMC Cancer
, vol.10
, pp. 454
-
-
Garcia, J.L.1
Perez-Caro, M.2
Gomez-Moreta, J.A.3
-
53
-
-
77957884258
-
Cancer stem-like cells of glioblastoma characteristically express MMP-13 and display highly invasive activity
-
Inoue A, Takahashi H, Harada H, et al. Cancer stem-like cells of glioblastoma characteristically express MMP-13 and display highly invasive activity. Int J Oncol 2010; 37: 1121-31.
-
(2010)
Int J Oncol
, vol.37
, pp. 1121-1131
-
-
Inoue, A.1
Takahashi, H.2
Harada, H.3
-
54
-
-
84874078913
-
Infiltrating growing pattern xenografts induced by glioblastoma and anaplastic astrocytoma derived tumor stem cells
-
Brehar FM, Ciurea AV, Zarnescu O, et al. Infiltrating growing pattern xenografts induced by glioblastoma and anaplastic astrocytoma derived tumor stem cells. Chirurgia (Bucur) 2010; 105: 685-94.
-
(2010)
Chirurgia (Bucur)
, vol.105
, pp. 685-694
-
-
Brehar, F.M.1
Ciurea, A.V.2
Zarnescu, O.3
-
55
-
-
63849225752
-
Human glioblastomaderived cancer stem cells: Establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors
-
Wakimoto H, Kesari S, Farrell CJ, et al. Human glioblastomaderived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Res 2009; 69: 3472-81.
-
(2009)
Cancer Res
, vol.69
, pp. 3472-3481
-
-
Wakimoto, H.1
Kesari, S.2
Farrell, C.J.3
-
56
-
-
79952281817
-
L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1
-
Cheng L, Wu Q, Huang Z, et al. L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1. EMBO J 2011; 30: 800-13.
-
(2011)
EMBO J
, vol.30
, pp. 800-813
-
-
Cheng, L.1
Wu, Q.2
Huang, Z.3
-
57
-
-
70349747011
-
Glioma tumor stem-like cells promote tumor angiogenesis and vasculogenesis via vascular endothelial growth factor and stromal-derived factor 1
-
Folkins C, Shaked Y, Man S, et al. Glioma tumor stem-like cells promote tumor angiogenesis and vasculogenesis via vascular endothelial growth factor and stromal-derived factor 1. Cancer Res 2009; 69: 7243-51.
-
(2009)
Cancer Res
, vol.69
, pp. 7243-7251
-
-
Folkins, C.1
Shaked, Y.2
Man, S.3
-
58
-
-
34447272949
-
VEGF promotes tumorigenesis and angiogenesis of human glioblastoma stem cells
-
Oka N, Soeda A, Inagaki A, et al. VEGF promotes tumorigenesis and angiogenesis of human glioblastoma stem cells. Biochem Biophys Res Commun 2007; 360: 553-9.
-
(2007)
Biochem Biophys Res Commun
, vol.360
, pp. 553-559
-
-
Oka, N.1
Soeda, A.2
Inagaki, A.3
-
59
-
-
49449117422
-
Glioblastoma stem cells produce vascular endothelial growth factor by activation of a G-protein coupled formylpeptide receptor FPR
-
Yao XH, Ping YF, Chen JH, et al. Glioblastoma stem cells produce vascular endothelial growth factor by activation of a G-protein coupled formylpeptide receptor FPR. J Pathol 2008; 215: 369-76.
-
(2008)
J Pathol
, vol.215
, pp. 369-376
-
-
Yao, X.H.1
Ping, Y.F.2
Chen, J.H.3
-
60
-
-
78650153633
-
Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
-
Ricci-Vitiani L, Pallini R, Biffoni M, et al. Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature 2010; 468: 824-8.
-
(2010)
Nature
, vol.468
, pp. 824-828
-
-
Ricci-Vitiani, L.1
Pallini, R.2
Biffoni, M.3
-
61
-
-
78650098659
-
Glioblastoma stem-like cells give rise to tumour endothelium
-
Wang R, Chadalavada K, Wilshire J, et al. Glioblastoma stem-like cells give rise to tumour endothelium. Nature 2010; 468: 829-33.
-
(2010)
Nature
, vol.468
, pp. 829-833
-
-
Wang, R.1
Chadalavada, K.2
Wilshire, J.3
-
62
-
-
58049198191
-
Brain cancer stem cells display preferential sensitivity to Akt inhibition
-
Eyler CE, Foo WC, LaFiura KM, McLendon RE, Hjelmeland AB, Rich JN. Brain cancer stem cells display preferential sensitivity to Akt inhibition. Stem Cells 2008; 26: 3027-36.
-
(2008)
Stem Cells
, vol.26
, pp. 3027-3036
-
-
Eyler, C.E.1
Foo, W.C.2
Lafiura, K.M.3
McLendon, R.E.4
Hjelmeland, A.B.5
Rich, J.N.6
-
63
-
-
77953215319
-
Invasive glioblastoma cells acquire stemness and increased Akt activation
-
Molina JR, Hayashi Y, Stephens C, Georgescu MM. Invasive glioblastoma cells acquire stemness and increased Akt activation. Neoplasia 2010; 12: 453-63.
-
(2010)
Neoplasia
, vol.12
, pp. 453-463
-
-
Molina, J.R.1
Hayashi, Y.2
Stephens, C.3
Georgescu, M.M.4
-
64
-
-
51049101689
-
Targeting cancer stem cells through L1CAM suppresses glioma growth
-
Bao S, Wu Q, Li Z, et al. Targeting cancer stem cells through L1CAM suppresses glioma growth. Cancer Res 2008; 68: 6043-8.
-
(2008)
Cancer Res
, vol.68
, pp. 6043-6048
-
-
Bao, S.1
Wu, Q.2
Li, Z.3
-
65
-
-
0030518746
-
ECM dependent and integrin mediated tumor cell migration of human glioma and melanoma cell lines under serumfree conditions
-
Goldbrunner RH, Haugland HK, Klein CE, Kerkau S, Roosen K, Tonn JC. ECM dependent and integrin mediated tumor cell migration of human glioma and melanoma cell lines under serumfree conditions. Anticancer Res 1996; 16: 3679-87.
-
(1996)
Anticancer Res
, vol.16
, pp. 3679-3687
-
-
Goldbrunner, R.H.1
Haugland, H.K.2
Klein, C.E.3
Kerkau, S.4
Roosen, K.5
Tonn, J.C.6
-
66
-
-
79953029992
-
Elevated invasive potential of glioblastoma stem cells
-
Cheng L, Wu Q, Guryanova OA, Huang Z, Huang Q, Rich JN, Bao S. Elevated invasive potential of glioblastoma stem cells. Biochem Biophys Res Commun 2011; 406: 643-8.
-
(2011)
Biochem Biophys Res Commun
, vol.406
, pp. 643-648
-
-
Cheng, L.1
Wu, Q.2
Guryanova, O.A.3
Huang, Z.4
Huang, Q.5
Rich, J.N.6
Bao, S.7
-
67
-
-
79952275286
-
Celecoxib and radioresistant glioblastoma-derived CD133+ cells: Improvement in radiotherapeutic effects. Laboratory investigation
-
Ma HI, Chiou SH, Hueng DY, et al. Celecoxib and radioresistant glioblastoma-derived CD133+ cells: improvement in radiotherapeutic effects. Laboratory investigation. J Neurosurg 2011; 114: 651-62.
-
(2011)
J Neurosurg
, vol.114
, pp. 651-662
-
-
Ma, H.I.1
Chiou, S.H.2
Hueng, D.Y.3
-
68
-
-
79954484430
-
Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy
-
Gong X, Schwartz PH, Linskey ME, Bota DA. Neural stem/progenitors and glioma stem-like cells have differential sensitivity to chemotherapy. Neurology 2011; 76: 1126-34.
-
(2011)
Neurology
, vol.76
, pp. 1126-1134
-
-
Gong, X.1
Schwartz, P.H.2
Linskey, M.E.3
Bota, D.A.4
-
69
-
-
33745198882
-
Chemotherapy resistance of glioblastoma stem cells
-
Eramo A, Ricci-Vitiani L, Zeuner A, et al. Chemotherapy resistance of glioblastoma stem cells. Cell Death Differ 2006; 13: 1238-41.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1238-1241
-
-
Eramo, A.1
Ricci-Vitiani, L.2
Zeuner, A.3
-
70
-
-
68249157942
-
Glioblastoma stem cells resistant to temozolomide-induced autophagy
-
Fu J, Liu ZG, Liu XM, et al. Glioblastoma stem cells resistant to temozolomide-induced autophagy. Chin Med J (Engl) 2009; 122: 1255-9.
-
(2009)
Chin Med J (Engl)
, vol.122
, pp. 1255-1259
-
-
Fu, J.1
Liu, Z.G.2
Liu, X.M.3
-
71
-
-
48649104080
-
Temozolomide preferentially depletes cancer stem cells in glioblastoma
-
Beier D, Rohrl S, Pillai DR, et al. Temozolomide preferentially depletes cancer stem cells in glioblastoma. Cancer Res 2008; 68: 5706-15.
-
(2008)
Cancer Res
, vol.68
, pp. 5706-5715
-
-
Beier, D.1
Rohrl, S.2
Pillai, D.R.3
-
72
-
-
78549288561
-
MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature
-
Gaspar N, Marshall L, Perryman L, et al. MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature. Cancer Res 2010; 70: 9243-52.
-
(2010)
Cancer Res
, vol.70
, pp. 9243-9252
-
-
Gaspar, N.1
Marshall, L.2
Perryman, L.3
-
73
-
-
77953125390
-
Influence of Etoposide on antiapoptotic and multidrug resistance-associated protein genes in CD133 positive U251 glioblastoma stem-like cells
-
Jin F, Zhao L, Guo YJ, et al. Influence of Etoposide on antiapoptotic and multidrug resistance-associated protein genes in CD133 positive U251 glioblastoma stem-like cells. Brain Res 2010; 1336: 103-11.
-
(2010)
Brain Res
, vol.1336
, pp. 103-111
-
-
Jin, F.1
Zhao, L.2
Guo, Y.J.3
-
74
-
-
77956189168
-
Study on the proliferation and drug-resistance of human brain tumor stem-like cells
-
Qin K, Jiang X, Zou Y, Wang J, Qin L, Zeng Y. Study on the proliferation and drug-resistance of human brain tumor stem-like cells. Cell Mol Neurobiol 2010; 30: 955-60.
-
(2010)
Cell Mol Neurobiol
, vol.30
, pp. 955-960
-
-
Qin, K.1
Jiang, X.2
Zou, Y.3
Wang, J.4
Qin, L.5
Zeng, Y.6
-
75
-
-
77955761867
-
Overexpression of CD133 promotes drug resistance in C6 glioma cells
-
Angelastro JM, Lame MW. Overexpression of CD133 promotes drug resistance in C6 glioma cells. Mol Cancer Res 2010; 8: 1105-15.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 1105-1115
-
-
Angelastro, J.M.1
Lame, M.W.2
-
76
-
-
77955381770
-
BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery
-
Facchino S, Abdouh M, Chatoo W, Bernier G. BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery. J Neurosci 2010; 30: 10096-111.
-
(2010)
J Neurosci
, vol.30
, pp. 10096-10111
-
-
Facchino, S.1
Abdouh, M.2
Chatoo, W.3
Bernier, G.4
-
77
-
-
80053302394
-
Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity
-
Zhuang W, Li B, Long L, Chen L, Huang Q, Liang Z. Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity. Int J Cancer 2011.
-
(2011)
Int J Cancer
-
-
Zhuang, W.1
Li, B.2
Long, L.3
Chen, L.4
Huang, Q.5
Liang, Z.6
-
78
-
-
78651359429
-
Knockdown of the DNA-dependent protein kinase catalytic subunit radiosensitizes glioma-initiating cells by inducing autophagy
-
Zhuang W, Li B, Long L, Chen L, Huang Q, Liang ZQ. Knockdown of the DNA-dependent protein kinase catalytic subunit radiosensitizes glioma-initiating cells by inducing autophagy. Brain Res 2011; 1371: 7-15.
-
(1371)
Brain Res
, vol.2011
, pp. 7-15
-
-
Zhuang, W.1
Li, B.2
Long, L.3
Chen, L.4
Huang, Q.5
Liang, Z.Q.6
-
79
-
-
67650095390
-
The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells
-
Lomonaco SL, Finniss S, Xiang C, et al. The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells. Int J Cancer 2009; 125: 717-22.
-
(2009)
Int J Cancer
, vol.125
, pp. 717-722
-
-
Lomonaco, S.L.1
Finniss, S.2
Xiang, C.3
-
80
-
-
74549187948
-
Glioma-associated cancer-initiating cells induce immunosuppression
-
Wei J, Barr J, Kong LY, et al. Glioma-associated cancer-initiating cells induce immunosuppression. Clin Cancer Res 2010; 16: 461-73.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 461-473
-
-
Wei, J.1
Barr, J.2
Kong, L.Y.3
-
81
-
-
73949096430
-
Glioblastoma cancerinitiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway
-
Wei J, Barr J, Kong LY, Wang Y, et al. Glioblastoma cancerinitiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway. Mol Cancer Ther 2010; 9: 67-78.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 67-78
-
-
Wei, J.1
Barr, J.2
Kong, L.Y.3
Wang, Y.4
-
82
-
-
76049114698
-
Immunobiological characterization of cancer stem cells isolated from glioblastoma patients
-
Di Tomaso T, Mazzoleni S, et al. Immunobiological characterization of cancer stem cells isolated from glioblastoma patients. Clin Cancer Res 2010; 16: 800-13.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 800-813
-
-
di Tomaso, T.1
Mazzoleni, S.2
-
83
-
-
78049270536
-
Glioma cancer stem cells induce immunosuppressive macrophages/microglia
-
Wu A, Wei J, Kong LY, Wang Y, Priebe W, Qiao W, Sawaya R, Heimberger AB. Glioma cancer stem cells induce immunosuppressive macrophages/microglia. Neuro Oncol 2010; 12: 1113-25.
-
(2010)
Neuro Oncol
, vol.12
, pp. 1113-1125
-
-
Wu, A.1
Wei, J.2
Kong, L.Y.3
Wang, Y.4
Priebe, W.5
Qiao, W.6
Sawaya, R.7
Heimberger, A.B.8
-
84
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RG, Hoadley KA, Purdom E, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010; 17: 98-110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
-
85
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
Phillips HS, Kharbanda S, Chen R, et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 2006; 9: 157-73.
-
(2006)
Cancer Cell
, vol.9
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
-
86
-
-
79955765058
-
DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression
-
Zheng S, Houseman EA, Morrison Z, et al. DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression. Neuro Oncol 2011; 13: 280-9.
-
(2011)
Neuro Oncol
, vol.13
, pp. 280-289
-
-
Zheng, S.1
Houseman, E.A.2
Morrison, Z.3
-
87
-
-
38349075007
-
CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells
-
Wang J, Sakariassen PO, Tsinkalovsky O, et al. CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. Int J Cancer 2008; 122: 761-8.
-
(2008)
Int J Cancer
, vol.122
, pp. 761-768
-
-
Wang, J.1
Sakariassen, P.O.2
Tsinkalovsky, O.3
-
88
-
-
67650727135
-
BMI1 sustains human glioblastoma multiforme stem cell renewal
-
Abdouh M, Facchino S, Chatoo W, Balasingam V, Ferreira J, Bernier G. BMI1 sustains human glioblastoma multiforme stem cell renewal. J Neurosci 2009; 29: 8884-96.
-
(2009)
J Neurosci
, vol.29
, pp. 8884-8896
-
-
Abdouh, M.1
Facchino, S.2
Chatoo, W.3
Balasingam, V.4
Ferreira, J.5
Bernier, G.6
-
89
-
-
59849125142
-
SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity
-
Gangemi RM, Griffero F, Marubbi D, et al. SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity. Stem Cells 2009; 27: 40-8.
-
(2009)
Stem Cells
, vol.27
, pp. 40-48
-
-
Gangemi, R.M.1
Griffero, F.2
Marubbi, D.3
-
90
-
-
56449126945
-
Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
-
Godlewski J, Nowicki MO, Bronisz A, et al. Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res 2008; 68: 9125-30.
-
(2008)
Cancer Res
, vol.68
, pp. 9125-9130
-
-
Godlewski, J.1
Nowicki, M.O.2
Bronisz, A.3
-
91
-
-
33846815345
-
Olig2-regulated lineagerestricted pathway controls replication competence in neural stem cells and malignant glioma
-
Ligon KL, Huillard E, Mehta S, et al. Olig2-regulated lineagerestricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron 2007; 53: 503-17.
-
(2007)
Neuron
, vol.53
, pp. 503-517
-
-
Ligon, K.L.1
Huillard, E.2
Mehta, S.3
-
92
-
-
79955543814
-
Melanoma stem cells: Not rare, but well done
-
Girouard SD, Murphy GF. Melanoma stem cells: not rare, but well done. Lab Invest 2011; 91: 647-64.
-
(2011)
Lab Invest
, vol.91
, pp. 647-664
-
-
Girouard, S.D.1
Murphy, G.F.2
-
93
-
-
75349091751
-
Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells
-
Charles N, Ozawa T, Squatrito M, et al. Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells. Cell Stem Cell 2010; 6: 141-52.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 141-152
-
-
Charles, N.1
Ozawa, T.2
Squatrito, M.3
-
94
-
-
77649273107
-
Hypoxia inducible factors in cancer stem cells
-
Heddleston JM, Li Z, Lathia JD, Bao S, Hjelmeland AB, Rich JN. Hypoxia inducible factors in cancer stem cells. Br J Cancer 2010; 102: 789-95.
-
(2010)
Br J Cancer
, vol.102
, pp. 789-795
-
-
Heddleston, J.M.1
Li, Z.2
Lathia, J.D.3
Bao, S.4
Hjelmeland, A.B.5
Rich, J.N.6
-
95
-
-
0042835825
-
Giant cell glioblastoma and pleomorphic xanthoastrocytoma show different immunohistochemical profiles for neuronal antigens and p53 but share reactivity for class III betatubulin
-
Martinez-Diaz H, Kleinschmidt-DeMasters BK, Powell SZ, Yachnis AT. Giant cell glioblastoma and pleomorphic xanthoastrocytoma show different immunohistochemical profiles for neuronal antigens and p53 but share reactivity for class III betatubulin. Arch Pathol Lab Med 2003; 127: 1187-91.
-
(2003)
Arch Pathol Lab Med
, vol.127
, pp. 1187-1191
-
-
Martinez-Diaz, H.1
Kleinschmidt-Demasters, B.K.2
Powell, S.Z.3
Yachnis, A.T.4
-
96
-
-
57449090950
-
Malignant gliomas with primitive neuroectodermal tumor-like components: A clinicopathologic and genetic study of 53 cases
-
Perry A, Miller CR, Gujrati M, et al. Malignant gliomas with primitive neuroectodermal tumor-like components: a clinicopathologic and genetic study of 53 cases. Brain Pathol 2009; 19: 81-90.
-
(2009)
Brain Pathol
, vol.19
, pp. 81-90
-
-
Perry, A.1
Miller, C.R.2
Gujrati, M.3
-
97
-
-
0034687840
-
Direct isolation of human central nervous system stem cells
-
Uchida N, Buck DW, He D, et al. Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A 2000; 97: 14720-5.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 14720-14725
-
-
Uchida, N.1
Buck, D.W.2
He, D.3
-
98
-
-
77950432267
-
CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of longterm cultured cancer stem cells from human malignant glioneuronal tumors
-
Patru C, Romao L, Varlet P, et al. CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of longterm cultured cancer stem cells from human malignant glioneuronal tumors. BMC Cancer 2010; 10: 66.
-
(2010)
BMC Cancer
, vol.10
, pp. 66
-
-
Patru, C.1
Romao, L.2
Varlet, P.3
-
99
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A, Weinberg RA. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 2008; 40: 499-507.
-
(2008)
Nat Genet
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
Ge, R.4
Bell, G.W.5
Regev, A.6
Weinberg, R.A.7
-
101
-
-
46449115281
-
Stem cell-related selfrenewal signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma
-
Murat A, Migliavacca E, Gorlia T, et al. Stem cell-related selfrenewal signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma. J Clin Oncol 2008; 26: 3015-24.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3015-3024
-
-
Murat, A.1
Migliavacca, E.2
Gorlia, T.3
-
102
-
-
58149340463
-
Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme
-
Pallini R, Ricci-Vitiani L, Banna GL, et al. Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme. Clin Cancer Res 2008; 14: 8205-12.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 8205-8212
-
-
Pallini, R.1
Ricci-Vitiani, L.2
Banna, G.L.3
-
103
-
-
40749155451
-
Stem cell marker CD133 affects clinical outcome in glioma patients
-
Zeppernick F, Ahmadi R, Campos B, et al. Stem cell marker CD133 affects clinical outcome in glioma patients. Clin Cancer Res 2008; 14: 123-9.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 123-129
-
-
Zeppernick, F.1
Ahmadi, R.2
Campos, B.3
-
104
-
-
77951911233
-
The intriguing links between prominin-1 (CD133), cholesterol-based membrane microdomains, remodeling of apical plasma membrane protrusions, extracellular membrane particles, and (neuro)epithelial cell differentiation
-
Corbeil D, Marzesco AM, Wilsch-Brauninger M, Huttner WB. The intriguing links between prominin-1 (CD133), cholesterol-based membrane microdomains, remodeling of apical plasma membrane protrusions, extracellular membrane particles, and (neuro)epithelial cell differentiation. FEBS Lett 2010; 584: 1659-64.
-
(2010)
FEBS Lett
, vol.584
, pp. 1659-1664
-
-
Corbeil, D.1
Marzesco, A.M.2
Wilsch-Brauninger, M.3
Huttner, W.B.4
-
105
-
-
34249978469
-
Asymmetric cell division within the human hematopoietic stem and progenitor cell compartment: Identification of asymmetrically segregating proteins
-
Beckmann J, Scheitza S, Wernet P, Fischer JC, Giebel B. Asymmetric cell division within the human hematopoietic stem and progenitor cell compartment: identification of asymmetrically segregating proteins. Blood 2007; 109: 5494-501.
-
(2007)
Blood
, vol.109
, pp. 5494-5501
-
-
Beckmann, J.1
Scheitza, S.2
Wernet, P.3
Fischer, J.C.4
Giebel, B.5
-
106
-
-
4944241261
-
Segregation of lipid raft markers including CD133 in polarized human hematopoietic stem and progenitor cells
-
Giebel B, Corbeil D, Beckmann J, et al. Segregation of lipid raft markers including CD133 in polarized human hematopoietic stem and progenitor cells. Blood 2004; 104: 2332-8.
-
(2004)
Blood
, vol.104
, pp. 2332-2338
-
-
Giebel, B.1
Corbeil, D.2
Beckmann, J.3
-
107
-
-
77956935369
-
Overexpression of CD133 promotes the phosphorylation of Erk in U87MG human glioblastoma cells
-
Dong L, Qi N, Ge RM, Cao CL, Lan F, Shen L. Overexpression of CD133 promotes the phosphorylation of Erk in U87MG human glioblastoma cells. Neurosci Lett 2010; 484: 210-4.
-
(2010)
Neurosci Lett
, vol.484
, pp. 210-214
-
-
Dong, L.1
Qi, N.2
Ge, R.M.3
Cao, C.L.4
Lan, F.5
Shen, L.6
-
108
-
-
70350362332
-
Effect of CD133/prominin-1 antisense oligodeoxynucleotide on in vitro growth characteristics of Huh-7 human hepatocarcinoma cells and U251 human glioma cells
-
Yao J, Zhang T, Ren J, Yu M, Wu G. Effect of CD133/prominin-1 antisense oligodeoxynucleotide on in vitro growth characteristics of Huh-7 human hepatocarcinoma cells and U251 human glioma cells. Oncol Rep 2009; 22: 781-7.
-
(2009)
Oncol Rep
, vol.22
, pp. 781-787
-
-
Yao, J.1
Zhang, T.2
Ren, J.3
Yu, M.4
Wu, G.5
-
109
-
-
76549120193
-
The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation
-
Kemper K, Sprick MR, de Bree M, et al. The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation. Cancer Res 2010; 70: 719-29.
-
(2010)
Cancer Res
, vol.70
, pp. 719-729
-
-
Kemper, K.1
Sprick, M.R.2
de Bree, M.3
-
110
-
-
77952788085
-
Glioblastoma cells negative for the anti-CD133 antibody AC133 express a truncated variant of the CD133 protein
-
Osmond TL, Broadley KW, McConnell MJ. Glioblastoma cells negative for the anti-CD133 antibody AC133 express a truncated variant of the CD133 protein. Int J Mol Med 2010; 25: 883-8.
-
(2010)
Int J Mol Med
, vol.25
, pp. 883-888
-
-
Osmond, T.L.1
Broadley, K.W.2
McConnell, M.J.3
-
112
-
-
77957918755
-
Mouse tissues express multiple splice variants of prominin-1
-
Kemper K, Tol MJ, Medema JP. Mouse tissues express multiple splice variants of prominin-1. PLoS One 2010; 5: e12325.
-
(2010)
PLoS One
, vol.5
-
-
Kemper, K.1
Tol, M.J.2
Medema, J.P.3
-
113
-
-
64849096118
-
The first extracellular domain of the tumour stem cell marker CD133 contains an antigenic ganglioside-binding motif
-
Taieb N, Maresca M, Guo XJ, Garmy N, Fantini J, Yahi N. The first extracellular domain of the tumour stem cell marker CD133 contains an antigenic ganglioside-binding motif. Cancer Lett 2009; 278: 164-73.
-
(2009)
Cancer Lett
, vol.278
, pp. 164-173
-
-
Taieb, N.1
Maresca, M.2
Guo, X.J.3
Garmy, N.4
Fantini, J.5
Yahi, N.6
-
114
-
-
65349115320
-
SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma
-
Son MJ, Woolard K, Nam DH, Lee J, Fine HA. SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Cell Stem Cell 2009; 4: 440-52.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 440-452
-
-
Son, M.J.1
Woolard, K.2
Nam, D.H.3
Lee, J.4
Fine, H.A.5
-
115
-
-
41749118669
-
Identification of A2B5+CD133- tumor-initiating cells in adult human gliomas
-
discussion 514-5
-
Ogden AT, Waziri AE, Lochhead RA, et al. Identification of A2B5+CD133- tumor-initiating cells in adult human gliomas. Neurosurgery 2008; 62: 505-14; discussion 514-5.
-
(2008)
Neurosurgery
, vol.62
, pp. 505-514
-
-
Ogden, A.T.1
Waziri, A.E.2
Lochhead, R.A.3
-
116
-
-
78649986150
-
TGF-beta Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma- Initiating Cell Population in Human Glioblastoma
-
Anido J, Saez-Borderias A, Gonzalez-Junca A, et al. TGF-beta Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma- Initiating Cell Population in Human Glioblastoma. Cancer Cell 2010; 18: 655-68.
-
(2010)
Cancer Cell
, vol.18
, pp. 655-668
-
-
Anido, J.1
Saez-Borderias, A.2
Gonzalez-Junca, A.3
-
117
-
-
77049103045
-
Brain Tumor Stem-Like Cells Identified by Neural Stem Cell Marker CD15
-
Mao XG, Zhang X, Xue XY, et al. Brain Tumor Stem-Like Cells Identified by Neural Stem Cell Marker CD15. Transl Oncol 2009; 2: 247-57.
-
(2009)
Transl Oncol
, vol.2
, pp. 247-257
-
-
Mao, X.G.1
Zhang, X.2
Xue, X.Y.3
-
118
-
-
71549129570
-
A2B5 cells from human glioblastoma have cancer stem cell properties
-
Tchoghandjian A, Baeza N, Colin C, et al. A2B5 cells from human glioblastoma have cancer stem cell properties. Brain Pathol 2010; 20: 211-21.
-
(2010)
Brain Pathol
, vol.20
, pp. 211-221
-
-
Tchoghandjian, A.1
Baeza, N.2
Colin, C.3
-
119
-
-
58649111264
-
Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma
-
Read TA, Fogarty MP, Markant SL, et al. Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma. Cancer Cell 2009; 15: 135-47.
-
(2009)
Cancer Cell
, vol.15
, pp. 135-147
-
-
Read, T.A.1
Fogarty, M.P.2
Markant, S.L.3
-
120
-
-
66349110796
-
Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma
-
Ward RJ, Lee L, Graham K, et al. Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma. Cancer Res 2009; 69: 4682-90.
-
(2009)
Cancer Res
, vol.69
, pp. 4682-4690
-
-
Ward, R.J.1
Lee, L.2
Graham, K.3
-
121
-
-
33644980252
-
LeX is expressed by principle progenitor cells in the embryonic nervous system, is secreted into their environment and binds Wnt-1
-
Capela A, Temple S. LeX is expressed by principle progenitor cells in the embryonic nervous system, is secreted into their environment and binds Wnt-1. Dev Biol 2006; 291: 300-13.
-
(2006)
Dev Biol
, vol.291
, pp. 300-313
-
-
Capela, A.1
Temple, S.2
-
122
-
-
0025359652
-
Monoclonal antibody A2B5, which detects cell surface antigens, binds to ganglioside GT3 (II3 (NeuAc)3LacCer) and to its 9-O-acetylated derivative
-
Dubois C, Manuguerra JC, Hauttecoeur B, Maze J. Monoclonal antibody A2B5, which detects cell surface antigens, binds to ganglioside GT3 (II3 (NeuAc)3LacCer) and to its 9-O-acetylated derivative. J Biol Chem 1990; 265: 2797-803.
-
(1990)
J Biol Chem
, vol.265
, pp. 2797-2803
-
-
Dubois, C.1
Manuguerra, J.C.2
Hauttecoeur, B.3
Maze, J.4
-
123
-
-
0344011434
-
Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis
-
Kim M, Morshead CM. Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis. J Neurosci 2003; 23: 10703-9.
-
(2003)
J Neurosci
, vol.23
, pp. 10703-10709
-
-
Kim, M.1
Morshead, C.M.2
-
124
-
-
0036297914
-
Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter
-
Lechner A, Leech CA, Abraham EJ, Nolan AL, Habener JF. Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter. Biochem Biophys Res Commun 2002; 293: 670-4.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 670-674
-
-
Lechner, A.1
Leech, C.A.2
Abraham, E.J.3
Nolan, A.L.4
Habener, J.F.5
-
125
-
-
0037106210
-
Flow cytometric analysis of neural stem cells in the developing and adult mouse brain
-
Murayama A, Matsuzaki Y, Kawaguchi A, Shimazaki T, Okano H. Flow cytometric analysis of neural stem cells in the developing and adult mouse brain. J Neurosci Res 2002; 69: 837-47.
-
(2002)
J Neurosci Res
, vol.69
, pp. 837-847
-
-
Murayama, A.1
Matsuzaki, Y.2
Kawaguchi, A.3
Shimazaki, T.4
Okano, H.5
-
126
-
-
70350759776
-
Identification and characterization of side population cells in embryonic stem cell cultures
-
Vieyra DS, Rosen A, Goodell MA. Identification and characterization of side population cells in embryonic stem cell cultures. Stem Cells Dev 2009; 18: 1155-66.
-
(2009)
Stem Cells Dev
, vol.18
, pp. 1155-1166
-
-
Vieyra, D.S.1
Rosen, A.2
Goodell, M.A.3
-
127
-
-
60849117508
-
PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
-
Bleau AM, Hambardzumyan D, Ozawa T, et al. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell 2009; 4: 226-35.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 226-235
-
-
Bleau, A.M.1
Hambardzumyan, D.2
Ozawa, T.3
-
128
-
-
22244433866
-
Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic
-
Patrawala L, Calhoun T, Schneider-Broussard R, Zhou J, Claypool K, Tang DG. Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic. Cancer Res 2005; 65: 6207-19.
-
(2005)
Cancer Res
, vol.65
, pp. 6207-6219
-
-
Patrawala, L.1
Calhoun, T.2
Schneider-Broussard, R.3
Zhou, J.4
Claypool, K.5
Tang, D.G.6
-
129
-
-
0034795256
-
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
-
Zhou S, Schuetz JD, Bunting KD, et al. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 2001; 7: 1028-34.
-
(2001)
Nat Med
, vol.7
, pp. 1028-1034
-
-
Zhou, S.1
Schuetz, J.D.2
Bunting, K.D.3
-
130
-
-
79953006501
-
Side population is not necessary or sufficient for a cancer stem cell phenotype in glioblastoma multiforme
-
Broadley KW, Hunn MK, Farrand KJ, et al. Side population is not necessary or sufficient for a cancer stem cell phenotype in glioblastoma multiforme. Stem Cells 2011; 29: 452-61.
-
(2011)
Stem Cells
, vol.29
, pp. 452-461
-
-
Broadley, K.W.1
Hunn, M.K.2
Farrand, K.J.3
-
131
-
-
77649273840
-
Marker-independent identification of glioma-initiating cells
-
Clement V, Marino D, Cudalbu C, et al. Marker-independent identification of glioma-initiating cells. Nat Methods 2010; 7: 224-8.
-
(2010)
Nat Methods
, vol.7
, pp. 224-228
-
-
Clement, V.1
Marino, D.2
Cudalbu, C.3
-
132
-
-
77956868654
-
Epidermal growth factor receptor in glioma: Signal transduction, neuropathology, imaging, and radioresistance
-
Hatanpaa KJ, Burma S, Zhao D, Habib AA. Epidermal growth factor receptor in glioma: signal transduction, neuropathology, imaging, and radioresistance. Neoplasia 2010; 12: 675-84.
-
(2010)
Neoplasia
, vol.12
, pp. 675-684
-
-
Hatanpaa, K.J.1
Burma, S.2
Zhao, D.3
Habib, A.A.4
-
133
-
-
77953285830
-
Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells
-
Ayuso-Sacido A, Moliterno JA, Kratovac S, et al. Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells. J Neurooncol 2010; 97: 323-37.
-
(2010)
J Neurooncol
, vol.97
, pp. 323-337
-
-
Ayuso-Sacido, A.1
Moliterno, J.A.2
Kratovac, S.3
-
134
-
-
77954367523
-
EGFR signaling is differentially activated in patientderived glioblastoma stem cells
-
Howard BM, Gursel DB, Bleau AM, Beyene RT, Holland EC, Boockvar JA. EGFR signaling is differentially activated in patientderived glioblastoma stem cells. J Exp Ther Oncol 2010; 8: 247-60.
-
(2010)
J Exp Ther Oncol
, vol.8
, pp. 247-260
-
-
Howard, B.M.1
Gursel, D.B.2
Bleau, A.M.3
Beyene, R.T.4
Holland, E.C.5
Boockvar, J.A.6
-
135
-
-
77957351780
-
Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis
-
Mazzoleni S, Politi LS, Pala M, et al. Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis. Cancer Res 2010; 70: 7500-13.
-
(2010)
Cancer Res
, vol.70
, pp. 7500-7513
-
-
Mazzoleni, S.1
Politi, L.S.2
Pala, M.3
-
136
-
-
58149239733
-
Roles of TGF-beta family signaling in stem cell renewal and differentiation
-
Watabe T, Miyazono K. Roles of TGF-beta family signaling in stem cell renewal and differentiation. Cell Res 2009; 19: 103-15.
-
(2009)
Cell Res
, vol.19
, pp. 103-115
-
-
Watabe, T.1
Miyazono, K.2
-
137
-
-
70350497349
-
Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors
-
Ikushima H, Todo T, Ino Y, Takahashi M, Miyazawa K, Miyazono K. Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors. Cell Stem Cell 2009; 5: 504-14.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 504-514
-
-
Ikushima, H.1
Todo, T.2
Ino, Y.3
Takahashi, M.4
Miyazawa, K.5
Miyazono, K.6
-
138
-
-
63249123273
-
TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma
-
Penuelas S, Anido J, Prieto-Sanchez RM, et al. TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma. Cancer Cell 2009; 15: 315-27.
-
(2009)
Cancer Cell
, vol.15
, pp. 315-327
-
-
Penuelas, S.1
Anido, J.2
Prieto-Sanchez, R.M.3
-
139
-
-
37349067098
-
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells
-
Lee J, Son MJ, Woolard K, Donin NM, et al. Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells. Cancer Cell 2008; 13: 69-80.
-
(2008)
Cancer Cell
, vol.13
, pp. 69-80
-
-
Lee, J.1
Son, M.J.2
Woolard, K.3
Donin, N.M.4
-
140
-
-
33845610993
-
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumourinitiating cells
-
Piccirillo SG, Reynolds BA, Zanetti N, et al. Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumourinitiating cells. Nature 2006; 444: 761-5.
-
(2006)
Nature
, vol.444
, pp. 761-765
-
-
Piccirillo, S.G.1
Reynolds, B.A.2
Zanetti, N.3
-
141
-
-
77954212388
-
Erythropoietin Receptor Signaling Through STAT3 Is Required For Glioma Stem Cell Maintenance
-
Cao Y, Lathia JD, Eyler CE, et al. Erythropoietin Receptor Signaling Through STAT3 Is Required For Glioma Stem Cell Maintenance. Genes Cancer 2010; 1: 50-61.
-
(2010)
Genes Cancer
, vol.1
, pp. 50-61
-
-
Cao, Y.1
Lathia, J.D.2
Eyler, C.E.3
-
142
-
-
51049088625
-
Erythropoiesis-stimulating agent use in cancer: Preclinical and clinical perspectives
-
Arcasoy MO. Erythropoiesis-stimulating agent use in cancer: preclinical and clinical perspectives. Clin Cancer Res 2008; 14: 4685-90.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4685-4690
-
-
Arcasoy, M.O.1
-
143
-
-
37149013962
-
Effects of recombinant erythropoietin on breast cancer-initiating cells
-
Phillips TM, Kim K, Vlashi E, McBride WH, Pajonk F. Effects of recombinant erythropoietin on breast cancer-initiating cells. Neoplasia 2007; 9: 1122-9.
-
(2007)
Neoplasia
, vol.9
, pp. 1122-1129
-
-
Phillips, T.M.1
Kim, K.2
Vlashi, E.3
McBride, W.H.4
Pajonk, F.5
-
144
-
-
34249005587
-
L1 expression as a marker for poor prognosis, tumor progression, and short survival in patients with colorectal cancer
-
Boo YJ, Park JM, Kim J, et al. L1 expression as a marker for poor prognosis, tumor progression, and short survival in patients with colorectal cancer. Ann Surg Oncol 2007; 14: 1703-11.
-
(2007)
Ann Surg Oncol
, vol.14
, pp. 1703-1711
-
-
Boo, Y.J.1
Park, J.M.2
Kim, J.3
-
145
-
-
0029925720
-
Gene expression of neural cell adhesion molecule L1 in malignant gliomas and biological significance of L1 in glioma invasion
-
Izumoto S, Ohnishi T, Arita N, Hiraga S, Taki T, Hayakawa T. Gene expression of neural cell adhesion molecule L1 in malignant gliomas and biological significance of L1 in glioma invasion. Cancer Res 1996; 56: 1440-4.
-
(1996)
Cancer Res
, vol.56
, pp. 1440-1444
-
-
Izumoto, S.1
Ohnishi, T.2
Arita, N.3
Hiraga, S.4
Taki, T.5
Hayakawa, T.6
-
146
-
-
13244290151
-
Clinicopathological study of cellular proliferation and invasion in gliomatosis cerebri: Important role of neural cell adhesion molecule L1 in tumour invasion
-
Suzuki T, Izumoto S, Fujimoto Y, Maruno M, Ito Y, Yoshimine T. Clinicopathological study of cellular proliferation and invasion in gliomatosis cerebri: important role of neural cell adhesion molecule L1 in tumour invasion. J Clin Pathol 2005; 58: 166-71.
-
(2005)
J Clin Pathol
, vol.58
, pp. 166-171
-
-
Suzuki, T.1
Izumoto, S.2
Fujimoto, Y.3
Maruno, M.4
Ito, Y.5
Yoshimine, T.6
-
147
-
-
33845882730
-
Neural recognition molecules of the immunoglobulin superfamily: Signaling transducers of axon guidance and neuronal migration
-
Maness PF, Schachner M. Neural recognition molecules of the immunoglobulin superfamily: signaling transducers of axon guidance and neuronal migration. Nat Neurosci 2007; 10: 19-26.
-
(2007)
Nat Neurosci
, vol.10
, pp. 19-26
-
-
Maness, P.F.1
Schachner, M.2
-
148
-
-
31444447881
-
Notch signalling in vertebrate neural development
-
Louvi A, Artavanis-Tsakonas S. Notch signalling in vertebrate neural development. Nat Rev Neurosci 2006; 7: 93-102.
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 93-102
-
-
Louvi, A.1
Artavanis-Tsakonas, S.2
-
149
-
-
75349105363
-
NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
-
Fan X, Khaki L, Zhu TS, et al. NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells 2010; 28: 5-16.
-
(2010)
Stem Cells
, vol.28
, pp. 5-16
-
-
Fan, X.1
Khaki, L.2
Zhu, T.S.3
-
150
-
-
77956623598
-
Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate
-
Hovinga KE, Shimizu F, Wang R, et al. Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate. Stem Cells 2010; 28: 1019-29.
-
(2010)
Stem Cells
, vol.28
, pp. 1019-1029
-
-
Hovinga, K.E.1
Shimizu, F.2
Wang, R.3
-
151
-
-
79951780026
-
Notch signaling contributes to the maintenance of both normal neural stem cells and patientderived glioma stem cells
-
Hu YY, Zheng MH, Cheng G, et al. Notch signaling contributes to the maintenance of both normal neural stem cells and patientderived glioma stem cells. BMC Cancer 2011; 11: 82.
-
(2011)
BMC Cancer
, vol.11
, pp. 82
-
-
Hu, Y.Y.1
Zheng, M.H.2
Cheng, G.3
-
152
-
-
36949031706
-
Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells
-
Zhang XP, Zheng G, Zou L, et al. Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells. Mol Cell Biochem 2008; 307: 101-8.
-
(2008)
Mol Cell Biochem
, vol.307
, pp. 101-108
-
-
Zhang, X.P.1
Zheng, G.2
Zou, L.3
-
153
-
-
78751640633
-
Inhibition of Sonic hedgehog and Notch pathways enhances sensitivity of CD133(+) glioma stem cells to temozolomide therapy
-
Ulasov IV, Nandi S, Dey M, Sonabend AM, Lesniak MS. Inhibition of Sonic hedgehog and Notch pathways enhances sensitivity of CD133(+) glioma stem cells to temozolomide therapy. Mol Med 2011; 17: 103-12.
-
(2011)
Mol Med
, vol.17
, pp. 103-112
-
-
Ulasov, I.V.1
Nandi, S.2
Dey, M.3
Sonabend, A.M.4
Lesniak, M.S.5
-
154
-
-
75349108271
-
Notch promotes radioresistance of glioma stem cells
-
Wang J, Wakeman TP, Lathia JD, et al. Notch promotes radioresistance of glioma stem cells. Stem Cells 2010; 28: 17-28.
-
(2010)
Stem Cells
, vol.28
, pp. 17-28
-
-
Wang, J.1
Wakeman, T.P.2
Lathia, J.D.3
-
155
-
-
62049085783
-
Making a grade: Sonic Hedgehog signalling and the control of neural cell fate
-
Briscoe J. Making a grade: Sonic Hedgehog signalling and the control of neural cell fate. EMBO J 2009; 28: 457-65.
-
(2009)
EMBO J
, vol.28
, pp. 457-465
-
-
Briscoe, J.1
-
156
-
-
58049193929
-
Hedgehog signaling regulates brain tumor-initiating cell proliferation and portends shorter survival for patients with PTEN-coexpressing glioblastomas
-
Xu Q, Yuan X, Liu G, Black KL, Yu JS. Hedgehog signaling regulates brain tumor-initiating cell proliferation and portends shorter survival for patients with PTEN-coexpressing glioblastomas. Stem Cells 2008; 26: 3018-26.
-
(2008)
Stem Cells
, vol.26
, pp. 3018-3026
-
-
Xu, Q.1
Yuan, X.2
Liu, G.3
Black, K.L.4
Yu, J.S.5
-
157
-
-
80052623307
-
Role of sonic hedgehog signaling in migration of cell lines established from CD133- positive malignant glioma cells
-
Uchida H, Arita K, Yunoue S, et al. Role of sonic hedgehog signaling in migration of cell lines established from CD133- positive malignant glioma cells. J Neurooncol 2011.
-
(2011)
J Neurooncol
-
-
Uchida, H.1
Arita, K.2
Yunoue, S.3
-
158
-
-
58149190329
-
Glioma formation, cancer stem cells, and akt signaling
-
Hambardzumyan D, Squatrito M, Carbajal E, Holland EC. Glioma formation, cancer stem cells, and akt signaling. Stem Cell Rev 2008; 4: 203-10.
-
(2008)
Stem Cell Rev
, vol.4
, pp. 203-210
-
-
Hambardzumyan, D.1
Squatrito, M.2
Carbajal, E.3
Holland, E.C.4
-
159
-
-
60849104091
-
Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells
-
Gallia GL, Tyler BM, Hann CL, et al. Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells. Mol Cancer Ther 2009; 8: 386-93.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 386-393
-
-
Gallia, G.L.1
Tyler, B.M.2
Hann, C.L.3
-
160
-
-
78649831949
-
Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells
-
Sunayama J, Matsuda K, Sato A, et al. Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells. Stem Cells 2010; 28: 1930-9.
-
(2010)
Stem Cells
, vol.28
, pp. 1930-1939
-
-
Sunayama, J.1
Matsuda, K.2
Sato, A.3
-
162
-
-
77954928427
-
Neural stem cells adopt tumorigenic properties by constitutively activated NF-kappaB and subsequent VEGF up-regulation
-
Kaus A, Widera D, Kassmer S, et al. Neural stem cells adopt tumorigenic properties by constitutively activated NF-kappaB and subsequent VEGF up-regulation. Stem Cells Dev 2010; 19: 999-1015.
-
(2010)
Stem Cells Dev
, vol.19
, pp. 999-1015
-
-
Kaus, A.1
Widera, D.2
Kassmer, S.3
-
163
-
-
77649100933
-
Targeting A20 decreases glioma stem cell survival and tumor growth
-
Hjelmeland AB, Wu Q, Wickman S, et al. Targeting A20 decreases glioma stem cell survival and tumor growth. PLoS Biol 2010; 8: e1000319.
-
(2010)
PLoS Biol
, vol.8
-
-
Hjelmeland, A.B.1
Wu, Q.2
Wickman, S.3
-
164
-
-
78649815101
-
STAT3 as a Therapeutic Target for Glioblastoma
-
Liu Y, Li C, Lin J. STAT3 as a Therapeutic Target for Glioblastoma. Anticancer Agents Med Chem 2010; 10: 512-9.
-
(2010)
Anticancer Agents Med Chem
, vol.10
, pp. 512-519
-
-
Liu, Y.1
Li, C.2
Lin, J.3
-
165
-
-
77954218647
-
Potential therapeutic implications of cancer stem cells in glioblastoma
-
Cheng L, Bao S, Rich JN. Potential therapeutic implications of cancer stem cells in glioblastoma. Biochem Pharmacol 2010; 80: 654-65.
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 654-665
-
-
Cheng, L.1
Bao, S.2
Rich, J.N.3
-
166
-
-
79953757100
-
Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3
-
Guryanova OA, Wu Q, Cheng L, et al. Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3. Cancer Cell 2011; 19: 498-511.
-
(2011)
Cancer Cell
, vol.19
, pp. 498-511
-
-
Guryanova, O.A.1
Wu, Q.2
Cheng, L.3
-
167
-
-
70350212976
-
STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells
-
Sherry MM, Reeves A, Wu JK, Cochran BH. STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells. Stem Cells 2009; 27: 2383-92.
-
(2009)
Stem Cells
, vol.27
, pp. 2383-2392
-
-
Sherry, M.M.1
Reeves, A.2
Wu, J.K.3
Cochran, B.H.4
-
168
-
-
78649876801
-
STAT3 is essential for the maintenance of neurosphere-initiating tumor cells in patients with glioblastomas: A potential for targeted therapy?
-
Villalva C, Martin-Lanneree S, Cortes U, et al. STAT3 is essential for the maintenance of neurosphere-initiating tumor cells in patients with glioblastomas: a potential for targeted therapy? Int J Cancer 2011; 128: 826-38.
-
(2011)
Int J Cancer
, vol.128
, pp. 826-838
-
-
Villalva, C.1
Martin-Lanneree, S.2
Cortes, U.3
-
169
-
-
14744305803
-
More than just proliferation: Myc function in stem cells
-
Murphy MJ, Wilson A, Trumpp A. More than just proliferation: Myc function in stem cells. Trends Cell Biol 2005; 15: 128-37.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 128-137
-
-
Murphy, M.J.1
Wilson, A.2
Trumpp, A.3
-
170
-
-
33748192942
-
The Myc oncoprotein as a therapeutic target for human cancer
-
Vita M, Henriksson M. The Myc oncoprotein as a therapeutic target for human cancer. Semin Cancer Biol 2006; 16: 318-30.
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 318-330
-
-
Vita, M.1
Henriksson, M.2
-
171
-
-
56849131763
-
C-Myc is required for maintenance of glioma cancer stem cells
-
Wang J, Wang H, Li Z, Wu Q, Lathia JD, McLendon RE, Hjelmeland AB, Rich JN. c-Myc is required for maintenance of glioma cancer stem cells. PLoS One 2008; 3: e3769.
-
(2008)
PLoS One
, vol.3
-
-
Wang, J.1
Wang, H.2
Li, Z.3
Wu, Q.4
Lathia, J.D.5
McLendon, R.E.6
Hjelmeland, A.B.7
Rich, J.N.8
-
172
-
-
33645469482
-
Stem cells and their niches
-
Moore KA, Lemischka IR. Stem cells and their niches. Science 2006; 311: 1880-5.
-
(2006)
Science
, vol.311
, pp. 1880-1885
-
-
Moore, K.A.1
Lemischka, I.R.2
-
173
-
-
0037071892
-
Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain
-
Louissaint A, Jr., Rao S, Leventhal C, Goldman SA. Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain. Neuron 2002; 34: 945-60.
-
(2002)
Neuron
, vol.34
, pp. 945-960
-
-
Louissaint Jr., A.1
Rao, S.2
Leventhal, C.3
Goldman, S.A.4
-
174
-
-
0034597430
-
Vascular niche for adult hippocampal neurogenesis
-
Palmer TD, Willhoite AR, Gage FH. Vascular niche for adult hippocampal neurogenesis. J Comp Neurol 2000; 425: 479-94.
-
(2000)
J Comp Neurol
, vol.425
, pp. 479-494
-
-
Palmer, T.D.1
Willhoite, A.R.2
Gage, F.H.3
-
175
-
-
33344455016
-
Pigment epithelium-derived factor is a niche signal for neural stem cell renewal
-
Ramirez-Castillejo C, Sanchez-Sanchez F, Andreu-Agullo C, et al. Pigment epithelium-derived factor is a niche signal for neural stem cell renewal. Nat Neurosci 2006; 9: 331-9.
-
(2006)
Nat Neurosci
, vol.9
, pp. 331-339
-
-
Ramirez-Castillejo, C.1
Sanchez-Sanchez, F.2
Andreu-Agullo, C.3
-
176
-
-
2542626091
-
Endothelial cells stimulate selfrenewal and expand neurogenesis of neural stem cells
-
Shen Q, Goderie SK, Jin L, et al. Endothelial cells stimulate selfrenewal and expand neurogenesis of neural stem cells. Science 2004; 304: 1338-40.
-
(2004)
Science
, vol.304
, pp. 1338-1340
-
-
Shen, Q.1
Goderie, S.K.2
Jin, L.3
-
178
-
-
33747874155
-
Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
-
Fan X, Matsui W, Khaki L, Stearns D, Chun J, Li YM, Eberhart CG. Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Res 2006; 66: 7445-52.
-
(2006)
Cancer Res
, vol.66
, pp. 7445-7452
-
-
Fan, X.1
Matsui, W.2
Khaki, L.3
Stearns, D.4
Chun, J.5
Li, Y.M.6
Eberhart, C.G.7
-
179
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000; 407: 249-57.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
180
-
-
44349157832
-
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
-
Dewhirst MW, Cao Y, Moeller B. Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response. Nat Rev Cancer 2008; 8: 425-37.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 425-437
-
-
Dewhirst, M.W.1
Cao, Y.2
Moeller, B.3
-
181
-
-
77954681705
-
The Relationship among Hypoxia, Proliferation, and Outcome in Patients with De Novo Glioblastoma: A Pilot Study
-
Evans SM, Jenkins KW, Chen HI, et al. The Relationship among Hypoxia, Proliferation, and Outcome in Patients with De Novo Glioblastoma: A Pilot Study. Transl Oncol 2010; 3: 160-9.
-
(2010)
Transl Oncol
, vol.3
, pp. 160-169
-
-
Evans, S.M.1
Jenkins, K.W.2
Chen, H.I.3
-
182
-
-
77952330272
-
Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma
-
Pistollato F, Abbadi S, Rampazzo E, et al. Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma. Stem Cells 2010; 28: 851-62.
-
(2010)
Stem Cells
, vol.28
, pp. 851-862
-
-
Pistollato, F.1
Abbadi, S.2
Rampazzo, E.3
-
183
-
-
78649364332
-
Hypoxia-inducible factors and the response to hypoxic stress
-
Majmundar AJ, Wong WJ, Simon MC. Hypoxia-inducible factors and the response to hypoxic stress. Mol Cell 2010; 40: 294-309.
-
(2010)
Mol Cell
, vol.40
, pp. 294-309
-
-
Majmundar, A.J.1
Wong, W.J.2
Simon, M.C.3
-
184
-
-
77952671059
-
Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: Implications for antiangiogenic mechanisms of multikinase inhibitors
-
Nilsson MB, Zage PE, Zeng L, et al. Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors. Oncogene 2010; 29: 2938-49.
-
(2010)
Oncogene
, vol.29
, pp. 2938-2949
-
-
Nilsson, M.B.1
Zage, P.E.2
Zeng, L.3
-
185
-
-
33644747418
-
HIF-2alpha regulates Oct-4: Effects of hypoxia on stem cell function, embryonic development, and tumor growth
-
Covello KL, Kehler J, Yu H, et al. HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev 2006; 20: 557-70.
-
(2006)
Genes Dev
, vol.20
, pp. 557-570
-
-
Covello, K.L.1
Kehler, J.2
Yu, H.3
-
186
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases
-
Zhong H, De Marzo AM, Laughner E, et al. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res 1999; 59: 5830-5.
-
(1999)
Cancer Res
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
de Marzo, A.M.2
Laughner, E.3
-
187
-
-
77952863838
-
Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres
-
Mendez O, Zavadil J, Esencay M, et al. Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres. Mol Cancer 2010; 9: 133.
-
(2010)
Mol Cancer
, vol.9
, pp. 133
-
-
Mendez, O.1
Zavadil, J.2
Esencay, M.3
-
188
-
-
4644231084
-
Expression of angiopoietins in renal epithelial and clear cell carcinoma cells: Regulation by hypoxia and participation in angiogenesis
-
Yamakawa M, Liu LX, Belanger AJ, et al. Expression of angiopoietins in renal epithelial and clear cell carcinoma cells: regulation by hypoxia and participation in angiogenesis. Am J Physiol Renal Physiol 2004; 287: F649-57.
-
(2004)
Am J Physiol Renal Physiol
, vol.287
-
-
Yamakawa, M.1
Liu, L.X.2
Belanger, A.J.3
-
189
-
-
54049146968
-
The angiopoietin-2 gene of endothelial cells is up-regulated in hypoxia by a HIF binding site located in its first intron and by the central factors GATA-2 and Ets-1
-
Simon MP, Tournaire R, Pouyssegur J. The angiopoietin-2 gene of endothelial cells is up-regulated in hypoxia by a HIF binding site located in its first intron and by the central factors GATA-2 and Ets-1. J Cell Physiol 2008; 217: 809-18.
-
(2008)
J Cell Physiol
, vol.217
, pp. 809-818
-
-
Simon, M.P.1
Tournaire, R.2
Pouyssegur, J.3
-
190
-
-
78651332826
-
Oxidative stress-induced attenuation of thrombospondin-1 expression in primary rat astrocytes
-
Chen JK, Zhan YJ, Yang CS, Tzeng SF. Oxidative stress-induced attenuation of thrombospondin-1 expression in primary rat astrocytes. J Cell Biochem 2011; 112: 59-70.
-
(2011)
J Cell Biochem
, vol.112
, pp. 59-70
-
-
Chen, J.K.1
Zhan, Y.J.2
Yang, C.S.3
Tzeng, S.F.4
-
191
-
-
0034658412
-
Thrombospondin-1 is downregulated by anoxia and suppresses tumorigenicity of human glioblastoma cells
-
Tenan M, Fulci G, Albertoni M, et al. Thrombospondin-1 is downregulated by anoxia and suppresses tumorigenicity of human glioblastoma cells. J Exp Med 2000; 191: 1789-98.
-
(2000)
J Exp Med
, vol.191
, pp. 1789-1798
-
-
Tenan, M.1
Fulci, G.2
Albertoni, M.3
-
192
-
-
0033924882
-
Opposing effects of hypoxia on expression of the angiogenic inhibitor thrombospondin 1 and the angiogenic inducer vascular endothelial growth factor
-
Laderoute KR, Alarcon RM, Brody MD, et al. Opposing effects of hypoxia on expression of the angiogenic inhibitor thrombospondin 1 and the angiogenic inducer vascular endothelial growth factor. Clin Cancer Res 2000; 6: 2941-50.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2941-2950
-
-
Laderoute, K.R.1
Alarcon, R.M.2
Brody, M.D.3
-
193
-
-
70350461699
-
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
-
Friedman HS, Prados MD, Wen PY, et al. Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol 2009; 27: 4733-40.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4733-4740
-
-
Friedman, H.S.1
Prados, M.D.2
Wen, P.Y.3
-
194
-
-
21244472780
-
Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size
-
Stier S, Ko Y, Forkert R, et al. Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. J Exp Med 2005; 201: 1781-91.
-
(2005)
J Exp Med
, vol.201
, pp. 1781-1791
-
-
Stier, S.1
Ko, Y.2
Forkert, R.3
-
195
-
-
21344474104
-
Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells
-
Nilsson SK, Johnston HM, Whitty GA, et al. Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. Blood 2005; 106: 1232-9.
-
(2005)
Blood
, vol.106
, pp. 1232-1239
-
-
Nilsson, S.K.1
Johnston, H.M.2
Whitty, G.A.3
-
196
-
-
77649084546
-
Mild hypoxia enhances proliferation and multipotency of human neural stem cells
-
Santilli G, Lamorte G, Carlessi L, et al. Mild hypoxia enhances proliferation and multipotency of human neural stem cells. PLoS One 2010; 5: e8575.
-
(2010)
PLoS One
, vol.5
-
-
Santilli, G.1
Lamorte, G.2
Carlessi, L.3
-
197
-
-
16344380951
-
Low O2 tensions and the prevention of differentiation of hES cells
-
Ezashi T, Das P, Roberts RM. Low O2 tensions and the prevention of differentiation of hES cells. Proc Natl Acad Sci U S A 2005; 102: 4783-8.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 4783-4788
-
-
Ezashi, T.1
Das, P.2
Roberts, R.M.3
-
198
-
-
69249210977
-
Hypoxia enhances the generation of induced pluripotent stem cells
-
Yoshida Y, Takahashi K, Okita K, Ichisaka T, Yamanaka S. Hypoxia enhances the generation of induced pluripotent stem cells. Cell Stem Cell 2009; 5: 237-41.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 237-241
-
-
Yoshida, Y.1
Takahashi, K.2
Okita, K.3
Ichisaka, T.4
Yamanaka, S.5
-
199
-
-
65549150903
-
Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro
-
McCord AM, Jamal M, Shankavarum UT, Lang FF, Camphausen K, Tofilon PJ. Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro. Mol Cancer Res 2009; 7: 489-97.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 489-497
-
-
McCord, A.M.1
Jamal, M.2
Shankavarum, U.T.3
Lang, F.F.4
Camphausen, K.5
Tofilon, P.J.6
-
200
-
-
79251591038
-
Glioblastoma, cancer stem cells and hypoxia
-
Bar EE. Glioblastoma, cancer stem cells and hypoxia. Brain Pathol 2011; 21: 119-29.
-
(2011)
Brain Pathol
, vol.21
, pp. 119-129
-
-
Bar, E.E.1
-
201
-
-
77956503727
-
Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres
-
Bar EE, Lin A, Mahairaki V, Matsui W, Eberhart CG. Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres. Am J Pathol 2010; 177: 1491-502.
-
(2010)
Am J Pathol
, vol.177
, pp. 1491-1502
-
-
Bar, E.E.1
Lin, A.2
Mahairaki, V.3
Matsui, W.4
Eberhart, C.G.5
-
202
-
-
59849096400
-
Hypoxia and HIF1alpha repress the differentiative effects of BMPs in high-grade glioma
-
Pistollato F, Chen HL, Rood BR, et al. Hypoxia and HIF1alpha repress the differentiative effects of BMPs in high-grade glioma. Stem Cells 2009; 27: 7-17.
-
(2009)
Stem Cells
, vol.27
, pp. 7-17
-
-
Pistollato, F.1
Chen, H.L.2
Rood, B.R.3
-
203
-
-
41549120198
-
Hypoxia-driven proliferation of embryonic neural stem/progenitor cells--role of hypoxia-inducible transcription factor-1alpha
-
Zhao T, Zhang CP, Liu ZH, et al. Hypoxia-driven proliferation of embryonic neural stem/progenitor cells--role of hypoxia-inducible transcription factor-1alpha. FEBS J 2008; 275: 1824-34.
-
(2008)
FEBS J
, vol.275
, pp. 1824-1834
-
-
Zhao, T.1
Zhang, C.P.2
Liu, Z.H.3
-
204
-
-
70349753257
-
HIF-2alpha maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells
-
Pietras A, Hansford LM, Johnsson AS, et al. HIF-2alpha maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells. Proc Natl Acad Sci U S A 2009; 106: 16805-10.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 16805-16810
-
-
Pietras, A.1
Hansford, L.M.2
Johnsson, A.S.3
-
205
-
-
57849147670
-
Smallmolecule inhibitors of HIF-2a translation link its 5'UTR ironresponsive element to oxygen sensing
-
Zimmer M, Ebert BL, Neil C, Brenner K, Papaioannou I, Melas A, Tolliday N, Lamb J, Pantopoulos K, Golub T, Iliopoulos O. Smallmolecule inhibitors of HIF-2a translation link its 5'UTR ironresponsive element to oxygen sensing. Molecular cell 2008; 32: 838-48.
-
(2008)
Molecular Cell
, vol.32
, pp. 838-848
-
-
Zimmer, M.1
Ebert, B.L.2
Neil, C.3
Brenner, K.4
Papaioannou, I.5
Melas, A.6
Tolliday, N.7
Lamb, J.8
Pantopoulos, K.9
Golub, T.10
Iliopoulos, O.11
-
206
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008; 455: 1061-8.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
207
-
-
79251629946
-
The genetic landscape of the childhood cancer medulloblastoma
-
Parsons DW, Li M, Zhang X, et al. The genetic landscape of the childhood cancer medulloblastoma. Science 2011; 331: 435-9.
-
(2011)
Science
, vol.331
, pp. 435-439
-
-
Parsons, D.W.1
Li, M.2
Zhang, X.3
-
208
-
-
0025135253
-
Histone-like protein H1 (HNS), DNA supercoiling, and gene expression in bacteria
-
Hulton CS, Seirafi A, Hinton JC, et al. Histone-like protein H1 (HNS), DNA supercoiling, and gene expression in bacteria. Cell 1990; 63: 631-42.
-
(1990)
Cell
, vol.63
, pp. 631-642
-
-
Hulton, C.S.1
Seirafi, A.2
Hinton, J.C.3
-
209
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A, Cuddapah S, Cui K, et al. High-resolution profiling of histone methylations in the human genome. Cell 2007; 129: 823-37.
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
-
210
-
-
34249299791
-
The complex language of chromatin regulation during transcription
-
Berger SL. The complex language of chromatin regulation during transcription. Nature 2007; 447: 407-12.
-
(2007)
Nature
, vol.447
, pp. 407-412
-
-
Berger, S.L.1
-
211
-
-
33847070442
-
The role of chromatin during transcription
-
Li B, Carey M, Workman JL. The role of chromatin during transcription. Cell 2007; 128: 707-19.
-
(2007)
Cell
, vol.128
, pp. 707-719
-
-
Li, B.1
Carey, M.2
Workman, J.L.3
-
212
-
-
0036850325
-
Cellular memory and the histone code
-
Turner BM. Cellular memory and the histone code. Cell 2002; 111: 285-91.
-
(2002)
Cell
, vol.111
, pp. 285-291
-
-
Turner, B.M.1
-
213
-
-
31544467813
-
De novo CpG island methylation in human cancer cells
-
Jair KW, Bachman KE, Suzuki H, et al. De novo CpG island methylation in human cancer cells. Cancer Res 2006; 66: 682-92.
-
(2006)
Cancer Res
, vol.66
, pp. 682-692
-
-
Jair, K.W.1
Bachman, K.E.2
Suzuki, H.3
-
214
-
-
77955449906
-
Epigenetic memory in induced pluripotent stem cells
-
Kim K, Doi A, Wen B, et al. Epigenetic memory in induced pluripotent stem cells. Nature 2010; 467: 285-90.
-
(2010)
Nature
, vol.467
, pp. 285-290
-
-
Kim, K.1
Doi, A.2
Wen, B.3
-
215
-
-
38049028459
-
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
-
Nakagawa M, Koyanagi M, Tanabe K, et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 2008; 26: 101-6.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 101-106
-
-
Nakagawa, M.1
Koyanagi, M.2
Tanabe, K.3
-
216
-
-
34249880066
-
Generation of germlinecompetent induced pluripotent stem cells
-
Okita K, Ichisaka T, Yamanaka S. Generation of germlinecompetent induced pluripotent stem cells. Nature 2007; 448: 313-7.
-
(2007)
Nature
, vol.448
, pp. 313-317
-
-
Okita, K.1
Ichisaka, T.2
Yamanaka, S.3
-
217
-
-
55849117368
-
Generation of mouse induced pluripotent stem cells without viral vectors
-
Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S. Generation of mouse induced pluripotent stem cells without viral vectors. Science 2008; 322: 949-53.
-
(2008)
Science
, vol.322
, pp. 949-953
-
-
Okita, K.1
Nakagawa, M.2
Hyenjong, H.3
Ichisaka, T.4
Yamanaka, S.5
-
218
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131: 861-72.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
219
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-76.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
220
-
-
77957551870
-
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
-
Li R, Liang J, Ni S, et al. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 2010; 7: 51-63.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 51-63
-
-
Li, R.1
Liang, J.2
Ni, S.3
-
221
-
-
33749039999
-
Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation
-
Cadieux B, Ching TT, VandenBerg SR, Costello JF. Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation. Cancer Res 2006; 66: 8469-76.
-
(2006)
Cancer Res
, vol.66
, pp. 8469-8476
-
-
Cadieux, B.1
Ching, T.T.2
Vandenberg, S.R.3
Costello, J.F.4
-
222
-
-
18144402837
-
Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8
-
Hong C, Maunakea A, Jun P, et al. Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8. Cancer Res 2005; 65: 3617-23.
-
(2005)
Cancer Res
, vol.65
, pp. 3617-3623
-
-
Hong, C.1
Maunakea, A.2
Jun, P.3
-
223
-
-
67649873216
-
Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy
-
Dunn J, Baborie A, Alam F, et al. Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy. Br J Cancer 2009; 101: 124-31.
-
(2009)
Br J Cancer
, vol.101
, pp. 124-131
-
-
Dunn, J.1
Baborie, A.2
Alam, F.3
-
224
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 2000; 343: 1350-4.
-
(2000)
N Engl J Med
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
-
225
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 2005; 352: 997-1003.
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
-
226
-
-
0037707818
-
Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis
-
Lessard J, Sauvageau G. Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis. Exp Hematol 2003; 31: 567-85.
-
(2003)
Exp Hematol
, vol.31
, pp. 567-585
-
-
Lessard, J.1
Sauvageau, G.2
-
227
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 2003; 423: 255-60.
-
(2003)
Nature
, vol.423
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
228
-
-
35148840173
-
Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma
-
Bruggeman SW, Hulsman D, Tanger E, et al. Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma. Cancer Cell 2007; 12: 328-41.
-
(2007)
Cancer Cell
, vol.12
, pp. 328-341
-
-
Bruggeman, S.W.1
Hulsman, D.2
Tanger, E.3
-
229
-
-
1642633053
-
Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
-
Leung C, Lingbeek M, Shakhova O, et al. Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas. Nature 2004; 428: 337-41.
-
(2004)
Nature
, vol.428
, pp. 337-341
-
-
Leung, C.1
Lingbeek, M.2
Shakhova, O.3
-
230
-
-
73649102464
-
EZH2 is essential for glioblastoma cancer stem cell maintenance
-
Suva ML, Riggi N, Janiszewska M, et al. EZH2 is essential for glioblastoma cancer stem cell maintenance. Cancer research 2009; 69: 9211-8.
-
(2009)
Cancer Research
, vol.69
, pp. 9211-9218
-
-
Suva, M.L.1
Riggi, N.2
Janiszewska, M.3
-
231
-
-
58949102947
-
Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells
-
Somervaille TC, Matheny CJ, Spencer GJ, et al. Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells. Cell Stem Cell 2009; 4: 129-40.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 129-140
-
-
Somervaille, T.C.1
Matheny, C.J.2
Spencer, G.J.3
-
232
-
-
0026454451
-
Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias
-
Tkachuk DC, Kohler S, Cleary ML. Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias. Cell 1992; 71: 691-700.
-
(1992)
Cell
, vol.71
, pp. 691-700
-
-
Tkachuk, D.C.1
Kohler, S.2
Cleary, M.L.3
-
233
-
-
33746849256
-
Regulation of MLL1 H3K4 methyltransferase activity by its core components
-
Dou Y, Milne TA, Ruthenburg AJ, et al. Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nat Struct Mol Biol 2006; 13: 713-9.
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 713-719
-
-
Dou, Y.1
Milne, T.A.2
Ruthenburg, A.J.3
-
234
-
-
71949107301
-
Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II
-
Wang P, Lin C, Smith ER, et al. Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II. Mol Cell Biol 2009; 29: 6074-85.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 6074-6085
-
-
Wang, P.1
Lin, C.2
Smith, E.R.3
-
235
-
-
35548934558
-
MLL translocations, histone modifications and leukaemia stem-cell development
-
Krivtsov AV, Armstrong SA. MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer 2007; 7: 823-33.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 823-833
-
-
Krivtsov, A.V.1
Armstrong, S.A.2
-
236
-
-
33749440584
-
Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia
-
Somervaille TC, Cleary ML. Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia. Cancer Cell 2006; 10: 257-68.
-
(2006)
Cancer Cell
, vol.10
, pp. 257-268
-
-
Somervaille, T.C.1
Cleary, M.L.2
-
237
-
-
0033598967
-
MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines
-
Huntsman DG, Chin SF, Muleris M, et al. MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines. Oncogene 1999; 18: 7975-84.
-
(1999)
Oncogene
, vol.18
, pp. 7975-7984
-
-
Huntsman, D.G.1
Chin, S.F.2
Muleris, M.3
-
238
-
-
64049095814
-
HOXA9 is required for survival in human MLL-rearranged acute leukemias
-
Faber J, Krivtsov AV, Stubbs MC, et al. HOXA9 is required for survival in human MLL-rearranged acute leukemias. Blood 2009; 113: 2375-85.
-
(2009)
Blood
, vol.113
, pp. 2375-2385
-
-
Faber, J.1
Krivtsov, A.V.2
Stubbs, M.C.3
-
239
-
-
77956944025
-
Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint
-
Liu H, Takeda S, Kumar R, et al. Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint. Nature 2010; 467: 343-6.
-
(2010)
Nature
, vol.467
, pp. 343-346
-
-
Liu, H.1
Takeda, S.2
Kumar, R.3
-
240
-
-
77952502408
-
A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth
-
Roesch A, Fukunaga-Kalabis M, Schmidt EC, et al. A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth. Cell 2010; 141: 583-94.
-
(2010)
Cell
, vol.141
, pp. 583-594
-
-
Roesch, A.1
Fukunaga-Kalabis, M.2
Schmidt, E.C.3
-
241
-
-
34250320926
-
Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases
-
Barrett A, Santangelo S, Tan K, et al. Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases. Int J Cancer 2007; 121: 265-75.
-
(2007)
Int J Cancer
, vol.121
, pp. 265-275
-
-
Barrett, A.1
Santangelo, S.2
Tan, K.3
-
242
-
-
37649023563
-
JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer
-
Xiang Y, Zhu Z, Han G, et al. JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer. Proc Natl Acad Sci U S A 2007; 104: 19226-31.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 19226-19231
-
-
Xiang, Y.1
Zhu, Z.2
Han, G.3
-
243
-
-
72249104107
-
Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells
-
Shen X, Kim W, Fujiwara Y, et al. Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells. Cell 2009; 139: 1303-14.
-
(2009)
Cell
, vol.139
, pp. 1303-1314
-
-
Shen, X.1
Kim, W.2
Fujiwara, Y.3
-
244
-
-
77949414371
-
JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells
-
Pasini D, Cloos PA, Walfridsson J, et al. JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells. Nature 2010; 464: 306-10.
-
(2010)
Nature
, vol.464
, pp. 306-310
-
-
Pasini, D.1
Cloos, P.A.2
Walfridsson, J.3
-
245
-
-
72249119297
-
Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells
-
Peng JC, Valouev A, Swigut T, Zhang J, Zhao Y, Sidow A, Wysocka J. Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. Cell 2009; 139: 1290-302.
-
(2009)
Cell
, vol.139
, pp. 1290-1302
-
-
Peng, J.C.1
Valouev, A.2
Swigut, T.3
Zhang, J.4
Zhao, Y.5
Sidow, A.6
Wysocka, J.7
-
246
-
-
51849102077
-
The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment
-
Burgold T, Spreafico F, De Santa F, et al. The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment. PLoS One 2008; 3: e3034.
-
(2008)
PLoS One
, vol.3
-
-
Burgold, T.1
Spreafico, F.2
de Santa, F.3
-
248
-
-
61349088682
-
The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF
-
Beyer S, Kristensen MM, Jensen KS, Johansen JV, Staller P. The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF. J Biol Chem 2008; 283: 36542-52.
-
(2008)
J Biol Chem
, vol.283
, pp. 36542-36552
-
-
Beyer, S.1
Kristensen, M.M.2
Jensen, K.S.3
Johansen, J.V.4
Staller, P.5
-
249
-
-
77956692764
-
Jumonji domain containing 1A is a novel prognostic marker for colorectal cancer: In vivo identification from hypoxic tumor cells
-
Uemura M, Yamamoto H, Takemasa I, et al. Jumonji domain containing 1A is a novel prognostic marker for colorectal cancer: in vivo identification from hypoxic tumor cells. Clin Cancer Res 2010; 16: 4636-46.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4636-4646
-
-
Uemura, M.1
Yamamoto, H.2
Takemasa, I.3
-
250
-
-
77955757491
-
The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth
-
Yang J, Jubb AM, Pike L, et al. The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth. Cancer Res 2010; 70: 6456-66.
-
(2010)
Cancer Res
, vol.70
, pp. 6456-6466
-
-
Yang, J.1
Jubb, A.M.2
Pike, L.3
-
251
-
-
70350353348
-
Role of hypoxia-inducible factors in epigenetic regulation via histone demethylases
-
Yang J, Ledaki I, Turley H, et al. Role of hypoxia-inducible factors in epigenetic regulation via histone demethylases. Ann N Y Acad Sci 2009; 1177: 185-97.
-
(2009)
Ann N Y Acad Sci
, vol.1177
, pp. 185-197
-
-
Yang, J.1
Ledaki, I.2
Turley, H.3
-
252
-
-
34547121206
-
Hypoxia in cancer: Significance and impact on clinical outcome
-
Vaupel P, Mayer A. Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev 2007; 26: 225-39.
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 225-239
-
-
Vaupel, P.1
Mayer, A.2
-
253
-
-
36049037819
-
Bevacizumab plus irinotecan in recurrent glioblastoma multiforme
-
Vredenburgh JJ, Desjardins A, Herndon JE, 2nd, et al. Bevacizumab plus irinotecan in recurrent glioblastoma multiforme. J Clin Oncol 2007; 25: 4722-9.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4722-4729
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Herndon 2nd, J.E.3
-
254
-
-
34648821254
-
Making a tumour's bed: Glioblastoma stem cells and the vascular niche
-
Gilbertson RJ, Rich JN. Making a tumour's bed: glioblastoma stem cells and the vascular niche. Nat Rev Cancer 2007; 7: 733-6.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 733-736
-
-
Gilbertson, R.J.1
Rich, J.N.2
-
255
-
-
34248550985
-
Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors
-
Folkins C, Man S, Xu P, Shaked Y, Hicklin DJ, Kerbel RS. Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors. Cancer Res 2007; 67: 3560-4.
-
(2007)
Cancer Res
, vol.67
, pp. 3560-3564
-
-
Folkins, C.1
Man, S.2
Xu, P.3
Shaked, Y.4
Hicklin, D.J.5
Kerbel, R.S.6
-
256
-
-
77949697909
-
Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice
-
Kioi M, Vogel H, Schultz G, Hoffman RM, Harsh GR, Brown JM. Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice. J Clin Invest 2010; 120: 694-705.
-
(2010)
J Clin Invest
, vol.120
, pp. 694-705
-
-
Kioi, M.1
Vogel, H.2
Schultz, G.3
Hoffman, R.M.4
Harsh, G.R.5
Brown, J.M.6
-
257
-
-
78751620483
-
The paradoxical effect of bevacizumab in the therapy of malignant gliomas
-
Thompson EM, Frenkel EP, Neuwelt EA. The paradoxical effect of bevacizumab in the therapy of malignant gliomas. Neurology 2011; 76: 87-93.
-
(2011)
Neurology
, vol.76
, pp. 87-93
-
-
Thompson, E.M.1
Frenkel, E.P.2
Neuwelt, E.A.3
-
258
-
-
74049090120
-
Concerns about antiangiogenic treatment in patients with glioblastoma multiforme
-
Verhoeff JJ, van Tellingen O, Claes A, et al. Concerns about antiangiogenic treatment in patients with glioblastoma multiforme. BMC Cancer 2009; 9: 444.
-
(2009)
BMC Cancer
, vol.9
, pp. 444
-
-
Verhoeff, J.J.1
van Tellingen, O.2
Claes, A.3
-
259
-
-
0142250392
-
Targeted antiinterleukin-6 monoclonal antibody therapy for cancer: A review of the rationale and clinical evidence
-
Trikha M, Corringham R, Klein B, Rossi JF. Targeted antiinterleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence. Clin Cancer Res 2003; 9: 4653-65.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4653-4665
-
-
Trikha, M.1
Corringham, R.2
Klein, B.3
Rossi, J.F.4
|