A case of organizing pneumonia induced by tocilizumab

Internal Medicine

Volumn 50, Issue 19, 2011, Pages 2191-2193

  Ikegawa, Kayoko ^a   Hanaoka, Masayuki ^a   Ushiki, Atsuhito ^a   Yamamoto, Hiroshi ^a   Kubo, Keishi ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Drug induced pneumonia; Organizing pneumonia; Tocilizumab

Indexed keywords

C REACTIVE PROTEIN; METHOTREXATE; METHYLPREDNISOLONE; PREDNISOLONE; TOCILIZUMAB;

ADULT; ARTICLE; BRONCHOGRAPHY; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CYTOLOGY; DRUG RESPONSE; DRUG WITHDRAWAL; EOSINOPHIL; FATIGUE; FEMALE; FIBEROPTIC BRONCHOSCOPY; HUMAN; KNEE PAIN; LABORATORY TEST; LIVER DISEASE; LUNG BIOPSY; LUNG LESION; ORGANIZING PNEUMONIA; PNEUMONIA; POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; TREATMENT DURATION;

ANTIBODIES, MONOCLONAL, HUMANIZED; ARTHRITIS, RHEUMATOID; FEMALE; HUMANS; METHOTREXATE; MIDDLE AGED; PNEUMONIA; RECEPTORS, INTERLEUKIN-6;

EID: 80053499547     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.50.5497     Document Type: Article

References (5)

1. Hushaw LL, Sawaqed R, Swies G, et al. Critical appraisal of tocilizumab in the treatment of moderate to severe rheumatoid arthritis. Ther Clinical Risk Manag 6: 143-152, 2010.
2. Hagiwaraz K, Sato T, Hirokazu Y, et al. LST for methotrexate in patients with rheumatoid arthritis. Allergy Clin Immunol Int: J World Allergy Org 17: 156-161, 2005.
3. Hirata S, Hattori N, Kumagai K, Haruta Y, Yokoyama A, Kohno N. Lymphocyte transformation test is not helpful for the diagnosis of methotrexate-induced pneumonitis in patients with rheumatoid arthritis. Clin Chim Acta 407: 25-29, 2009.
4. Smolen JS, Beaulieu A, Rubbert-Roth A, et al. Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebocontrolled, randomized trial. Lancet 371: 987-997, 2008.
5. Campbell L, Chen C, Bhagat SS, Parker RA, Östör AJ. Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab: a systematic literature review and meta-analysis of randomized controlled trails. Rheumatology (Oxford) 50: 552-562, 2010.