Luciferase-expressing Leishmania infantum allows the monitoring of amastigote population size, in vivo, ex vivo and in vitro

PLoS Neglected Tropical Diseases

Volumn 5, Issue 9, 2011, Pages

  Michel, Grégory ^a,b,c,d   Ferrua, Bernard ^a,c   Lang, Thierry ^e   Maddugoda, Madhavi P ^c   Munro, Patrick ^c   Pomares, Christelle ^a,c,d   Lemichez, Emmanuel ^c   Marty, Pierre ^a,c,d  

^a UNIVERSITÉ CÔTE D'AZUR   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

^c CENTRE MÉDITERRANÉEN DE MÉDECINE MOLÉCULAIRE C3M   (France)

^d UNIVERSITY HOSPITAL OF NICE   (France)

^e INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

LUCIFERASE; MILTEFOSINE; ANTIPROTOZOAL AGENT; DRUG DERIVATIVE; PHOSPHORYLCHOLINE; PROTOZOAL PROTEIN;

AMASTIGOTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MONITORING; BIOLUMINESCENCE; BIOMASS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG SCREENING; EX VIVO STUDY; IC 50; IN VITRO STUDY; IN VIVO STUDY; LEISHMANIA INFANTUM; LEISHMANIA INFANTUM INFECTION; LIVER; MOUSE; NONHUMAN; PARASITE LOAD; PARASITOSIS; POPULATION SIZE; PROMASTIGOTE; PROTEIN EXPRESSION; SPLEEN; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CHEMISTRY; ENZYMOLOGY; FEMALE; GENETICS; ISOLATION AND PURIFICATION; LIFE CYCLE STAGE; LUMINESCENCE; METHODOLOGY; NONPARAMETRIC TEST; PARASITOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SPECTROSCOPY; TRANSGENIC ORGANISM; VISCERAL LEISHMANIASIS; WHOLE BODY IMAGING;

ANIMALS; ANTIPROTOZOAL AGENTS; DRUG EVALUATION, PRECLINICAL; FEMALE; LEISHMANIA INFANTUM; LEISHMANIASIS, VISCERAL; LIFE CYCLE STAGES; LIVER; LUCIFERASES; LUMINESCENT MEASUREMENTS; MICE; MICE, INBRED BALB C; ORGANISMS, GENETICALLY MODIFIED; PARASITE LOAD; PHOSPHORYLCHOLINE; PROTOZOAN PROTEINS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTRUM ANALYSIS; SPLEEN; STATISTICS, NONPARAMETRIC; WHOLE BODY IMAGING;

EID: 80053449835     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001323     Document Type: Article

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