The complete pharmacokinetic profile of serum cardiac troponin I in the rat and the dog

Toxicological Sciences

Volumn 123, Issue 2, 2011, Pages 368-373

  Dunn, Michael E ^a   Coluccio, Denise ^a   Hirkaler, Gerard ^a   Mikaelian, Igor ^a   Nicklaus, Rosemary ^a   Lipshultz, Steven E ^b   Doessegger, Lucette ^c   Reddy, Micaela ^a   Singer, Thomas ^c   Geng, Wanping ^a  

^a HOFFMANN LA ROCHE INC   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Biomarker; Cardiac troponin I; Dog; Kinetics; Rat; Ultrasensitive assay

Indexed keywords

TROPONIN I;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; EXPERIMENTAL DOG; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PROTEIN BLOOD LEVEL; RAT; TOXICITY TESTING;

ANIMALS; DOGS; INJECTIONS, INTRAVENOUS; MALE; RATS; RATS, WISTAR; SPECIES SPECIFICITY; TROPONIN I;

CANIS FAMILIARIS; RATTUS;

EID: 80053449638     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr190     Document Type: Article

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