Targeting of a chlamydial protease impedes intracellular bacterial growth

PLoS Pathogens

Volumn 7, Issue 9, 2011, Pages

  Christian, Jan G ^a,b   Heymann, Julia ^c,d   Paschen, Stefan A ^a   Vier, Juliane ^b   Schauenburg, Linda ^a   Rupp, Jan ^e,f   Meyer, Thomas F ^c   Häcker, Georg ^b   Heuer, Dagmar ^c,d  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

^d ROBERT KOCH INSTITUTE   (Germany)

^e UNIVERSITY OF LÜBECK   (Germany)

^f Medical Clinic III   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLLEUCYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLTRYPTOPHYLLGLUTAMYLHISTIDYLASPARTYLFLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLGLUTAMYLISOLEUCYLASPARTYL FLUOROMETHYL KETONE; CASPASE INHIBITOR; CELL PROTEIN; CHLAMYDIAL PROTEASE LIKE ACTIVITY FACTOR; GOLGIN 84 PROTEIN; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATASE RAB11; GUANOSINE TRIPHOSPHATASE RAB6; PROTEINASE; UNCLASSIFIED DRUG; VIMENTIN; CPA FACTOR; GOLGA5 PROTEIN, HUMAN; MEMBRANE PROTEIN; OLIGOPEPTIDE; RAB PROTEIN; RAB11 PROTEIN; RAB6 PROTEIN; SMALL INTERFERING RNA; TRYPTOPHYL GLUTAMYL HISTIDYL ASPARTIC ACID; TRYPTOPHYL-GLUTAMYL-HISTIDYL-ASPARTIC ACID;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; CELLULAR DISTRIBUTION; CHLAMYDIA; CHLAMYDIA TRACHOMATIS; CHLAMYDIAL PNEUMONIA; CHLAMYDIASIS; CHLAMYDOPHILA PNEUMONIAE; CONTROLLED STUDY; DRUG TARGETING; EPITHELIUM CELL; GENE DOSAGE; GOLGI COMPLEX; GROWTH INHIBITION; HELA CELL; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; BIOSYNTHESIS; CELL FREE SYSTEM; CELL LINE; CELL STRAIN HEK293; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; RNA INTERFERENCE;

BACTERIA (MICROORGANISMS); CHLAMYDIA; CHLAMYDIA TRACHOMATIS; CHLAMYDIAE; CHLAMYDOPHILA PNEUMONIAE;

CELL LINE; CELL-FREE SYSTEM; CHLAMYDIA TRACHOMATIS; CHLAMYDOPHILA PNEUMONIAE; ENDOPEPTIDASES; GOLGI APPARATUS; HEK293 CELLS; HELA CELLS; HUMANS; MEMBRANE PROTEINS; OLIGOPEPTIDES; RAB GTP-BINDING PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 80053449258     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002283     Document Type: Article

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