Murine gamma-herpesvirus immortalization of fetal liver-derived b cells requires both the viral cyclin d homolog and latency-associated nuclear antigen

PLoS Pathogens

Volumn 7, Issue 9, 2011, Pages

  Liang, Xiaozhen ^a   Paden, Clinton R ^a   Morales, Francine M ^a   Powers, Ryan P ^a   Jacob, Joshy ^a   Speck, Samuel H ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D; LATENCY ASSOCIATED NUCLEAR ANTIGEN; VIRUS ANTIGEN; LATENCY-ASSOCIATED NUCLEAR ANTIGEN; NUCLEAR PROTEIN; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN DETECTION; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE DIFFERENTIATION; CANCER MODEL; CELL IMMORTALIZATION; CONTROLLED STUDY; FEMALE; FETUS; FETUS LIVER; GAMMAHERPESVIRINAE; GENETIC TRANSCRIPTION; IN VITRO STUDY; IN VIVO STUDY; LYMPHOMA; MOUSE; MURINE GAMMAHERPESVIRINAE; NONHUMAN; PHENOTYPE; ANIMAL; B CELL LYMPHOMA; C57BL MOUSE; CELL LINE; CYTOLOGY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE REARRANGEMENT; GENETICS; LIVER; METABOLISM; NUDE MOUSE; PATHOGENICITY; PHYSIOLOGY; PLASMA CELL; RHADINOVIRUS; SEQUENCE ANALYSIS; VIROLOGY; VIRUS CELL TRANSFORMATION; VIRUS GENE; VIRUS REPLICATION;

ANIMALIA; HERPESVIRIDAE; HUMAN HERPESVIRUS 8; MURINAE; MUS; RODENTIA;

ANIMALS; ANTIGENS, VIRAL; B-LYMPHOCYTES; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, VIRAL; CYCLIN D; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, VIRAL; GENE REARRANGEMENT; GENES, VIRAL; LIVER; LYMPHOMA, B-CELL; MICE; MICE, INBRED C57BL; MICE, NUDE; MODELS, ANIMAL; NUCLEAR PROTEINS; PHENOTYPE; PLASMA CELLS; RHADINOVIRUS; SEQUENCE ANALYSIS, RNA; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 80053438075     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002220     Document Type: Article

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