Increased serum leptin indicates leptin resistance in obesity

Clinical Chemistry

Volumn 57, Issue 10, 2011, Pages 1461-1462

  Considine, Robert Vincent ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; PROTEIN ANTIBODY;

GENE EXPRESSION; HORMONE BLOOD LEVEL; HUMAN; LEPTIN BLOOD LEVEL; NONHUMAN; NOTE; OBESITY; PROADIPOCYTE;

FEMALE; HUMANS; MALE; OBESITY; PROTEINS;

EID: 80053413554     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2011.166421     Document Type: Note

References (4)

1. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994;372:425-32; erratum 1995;374:479.
2. Considine RV, Considine EL, Williams CJ, Nyce MR, Magosin SA, Bauer TL, et al. Evidence against either a premature stop codon or the absence of Ob gene mRNA in human obesity. J Clin Invest 1995;95:2986-8.
3. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1995;1:1155-61.
4. Caro JF, Considine RV. Leptin: from laboratory to clinic. In: Bray GA, Bouchard C, eds. Handbook of obesity. 2nd ed. New York: Marcel Dekker; 2004. p 275-95.