Using water-soluble C60 fullerenes in anticancer therapy

Cancer Nanotechnology

Volumn 2, Issue 1-6, 2011, Pages 105-110

  Prylutska, S V ^a   Burlaka, A P ^b   Klymenko, P P ^c   Grynyuk, I I ^a   Prylutskyy, Yu I ^a   Schütze, Ch ^d   Ritter, U ^d  

^a TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

^b R E KAVETSKY INSTITUTE OF EXPERIMENTAL PATHOLOGY   (Ukraine)

^c INSTITUTE OF GERONTOLOGY   (Ukraine)

^d ILMENAU UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

C60 fullerenes; Histological data; Increasing of animal life; Lewis lung carcinoma; Metastasis inhibition index; Mice line C57Bl 6J; Survival of animals; Tumor growth inhibition

Indexed keywords

ENDOTHELIAL CELL GROWTH FACTOR; FULLERENE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER PREVENTION; CONTROLLED STUDY; DRUG MECHANISM; LEWIS CARCINOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 80053391141     PISSN: 18686958     EISSN: 18686966     Source Type: Journal    
DOI: 10.1007/s12645-011-0020-x     Document Type: Article

References (20)

1. 60 fullerene molecule toxic?! Fullerenes, Nanotubes, and Carbon Nanostruct 13: 363-376.
2. Boyle P, Levin B (2008) World cancer report. WHO, Lyon.
3. 60 in aqueous solution. Phys Chem Chem Phys 2: 1627-1629.
4. Carmeliet P (2005) Angiogenesis in life, disease and medicine. Nature 438: 932-936.
5. Cataldo F, Da Ros T (eds) (2008) Medicinal chemistry and pharmacological potential of fullerenes and carbon nanotubes. Series: Carbon materials: chemistry and physics. Springer, Netherlands.
6. Foley S, Crowley C, Smaihi M, Bonfils C, Erlanger BF, Seta P, Larroque Ch (2002) Cellular localisation of a water-soluble fullerene derivative. Biochem Biophys Res Commun 294: 116-119.
7. Freitas RA Jr (2003) Nanomedicine, volume IIA: biocompatibility. Landes Bioscience, Georgetown.
8. 60 fullerene is a powerful antioxidant in vivo with no acute or subacute toxicity. Nano Lett 5: 2578-2585.
9. Gubler EV (1978) Computational methods of analysis and recognition of pathological processes. Medicine, Moscow.
10. Johnston HJ, Hutchison GR, Christensen FM, Aschberger K, Stone V (2010) The biological mechanisms and physicochemical characteristics responsible for driving fullerene toxicity. Toxicol Sci 114: 162-182.
11. Meng H, Xing G, Sun B, Zhao F, Lei H, Li W et al (2010) Potent angiogenesis inhibition by the particulate form of fullerene derivatives. ASC Nano 4: 2773-2783.
12. Murugesan S, Mousa SA, O'Connor LJ, Lincoln DW, Linhardt RJ (2007) Carbon inhibits vascular endothelial growth factor- and fibroblast growth factor-promoted angiogenesis. FEBS Lett 581: 1157-1160.
13. 60-containing composites cytotoxicity in vitro. Mater Sci Engineer C 27: 1121-1124.
14. 60 fullerenes in vitro. Fullerenes, Nanotubes, and Carbon Nanostruct 16: 698-705.
15. 60 fullerenes as anticancer agents in the therapy of malignant tumors. Patent of Ukraine for an invention N a201104882, 14 April 2011.
16. 60 nanoparticles in water solution and on the support. Eur Phys J D 9: 341-343.
17. 60 fullerene in water: spectroscopic data. Carbon 42: 1203-1206.
18. 60 fullerenes on the hydrated properties of nanocomposites based on highly dispersed silica and DNA. Chem Phys Lett 496: 152-156.
19. Yin JJ, Lao F, Fu PP, Zhao Y, Xing G, Gao X et al (2008) Inhibition of tumor growth by endohedral metallofullerenol nanoparticles optimized as reactive oxygen species scavenger. Mol Pharmacol 74: 1132-1140.
20. Yin JJ, Lao F, Fu PP, Wamer WG, Zhao Y, Wang PC et al (2009) The scavenging of reactive oxygen species and the potential for cell protection by functionalized fullerene materials. Biomaterials 30: 611-621.