Radiosurgery versus Surgery, both with Adjuvant Whole Brain Radiotherapy, for Solitary Brain Metastases: A Randomised Controlled Trial

Clinical Oncology

Volumn 23, Issue 9, 2011, Pages 646-651

  Roos, D E ^a   Smith, J G ^b   Stephens, S W ^a  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

^b Plain Statistics Pty Ltd   (Australia)

Author keywords

Adjuvant whole brain radiotherapy; Brain metastasis; Radiosurgery; Randomised controlled trial; Surgery

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN METASTASIS; BRAIN SURGERY; CANCER ADJUVANT THERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SIZE; CANCER SURGERY; CANCER SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DISEASE SEVERITY; FATIGUE; FEMALE; FOLLOW UP; FUNCTIONAL STATUS; HEARING LOSS; HUMAN; KARNOFSKY PERFORMANCE STATUS; MALE; NERVOUS SYSTEM FUNCTION; NUCLEAR MAGNETIC RESONANCE IMAGING; OVERALL SURVIVAL; PRIORITY JOURNAL; QUALITY OF LIFE; RADIATION DOSE FRACTIONATION; RADIATION INJURY; RADIOSURGERY; RANDOMIZED CONTROLLED TRIAL; SURVIVAL TIME; TREATMENT FAILURE;

ADULT; AGED; AGED, 80 AND OVER; BRAIN NEOPLASMS; CRANIAL IRRADIATION; FEMALE; HUMANS; MALE; MIDDLE AGED; PROGNOSIS; QUALITY OF LIFE; RADIOSURGERY; RADIOTHERAPY, ADJUVANT; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 80053384836     PISSN: 09366555     EISSN: 14332981     Source Type: Journal    
DOI: 10.1016/j.clon.2011.04.009     Document Type: Article

References (6)

1. Gaspar L., Scott C., Rotman M., et al. Recursive partitioning analysis (RPA) of prognostic factors in three radiation therapy oncology group (RTOG) brain metastases trials. Int J Radiat Oncol Biol Phys 1997, 37:745-751.
2. Roos D.E. Commentary: what is the randomised evidence for surgery and stereotactic radiosurgery for patients with solitary (or few) brain metastases?. Int J Evidence-Based Healthcare 2011, 9:61-66.
3. Lutterbach J., Bartelt S., Stancu E., Guttenberger R. Patients with brain metastases: hope for recursive partitioning analysis (RPA) class 3. Radiother Oncol 2002, 63:339-345.
4. Shaw E., Scott C., Souhami L., et al. Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases: final report of RTOG protocol 90-05. Int J Radiat Oncol Biol Phys 2000, 47:291-298.
5. Piaggio G., Elbourne D.R., Altman D.G., Pocock S.J. Evans SJW for the CONSORT group. Reporting of noninferiority and equivalence randomized trials: an extension of the CONSORT statement. JAMA 2006, 295:1152-1160.
6. Jones B., Jarvis P., Lewis J.A., Ebbutt A.F. Trials to assess equivalence: the importance of rigorous methods. Brit Med J 1996, 313:36-39. 550.