Rapid pyrophosphate release from transcriptional elongation complexes appears to be coupled to a nucleotide-induced conformational change in E. coli core polymerase

Journal of Molecular Biology

Volumn 412, Issue 5, 2011, Pages 849-861

  Johnson, Ronald S ^a   Strausbauch, Mark ^a   Carraway, J Kristen ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

Author keywords

elongation; pyrophosphate release; RNA polymerase; stopped flow and quench flow kinetics; transcription

Indexed keywords

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; BACTERIAL ENZYME; CORE POLYMERASE; NUCLEOTIDE; PYROPHOSPHATE; TRANSCRIPTION ELONGATION FACTOR; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE;

ARTICLE; ENZYME CONFORMATION; ESCHERICHIA COLI; FLOW KINETICS; FLUORESCENCE; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; RNA TRANSLATION;

EID: 80053378346     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.05.023     Document Type: Article

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