Using emergency department-based inception cohorts to determine genetic characteristics associated with long term patient outcomes after motor vehicle collision: Methodology of the CRASH study

BMC Emergency Medicine

Volumn 11, Issue , 2011, Pages

  Platts Mills, Timothy F ^a   Ballina, Lauren ^a   Bortsov, Andrey V ^a   Soward, April ^a   Swor, Robert A ^b   Jones, Jeffrey S ^c   Lee, David C ^d   Peak, David A ^e   Domeier, Robert M ^f   Rathlev, Niels K ^g   Hendry, Phyllis L ^h   McLean, Samuel A ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b WILLIAM BEAUMONT HOSPITAL   (United States)

^c Spectrum Health Butterworth Campus ^*  (United States)

^d NORTH SHORE UNIVERSITY HOSPITAL   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f ST JOSEPH MERCY HOSPITAL   (United States)

^g BAYSTATE MEDICAL CENTER   (United States)

^h UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; CATECHOLAMINE;

ADRENERGIC SYSTEM; ARTICLE; EMERGENCY WARD; GENETIC VARIABILITY; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; MUSCULOSKELETAL PAIN; PAIN ASSESSMENT; PATHOGENESIS; POSTTRAUMATIC PAIN; POSTTRAUMATIC STRESS DISORDER; PSYCHOLOGICAL ASPECT; SOCIAL ASPECT; TRAFFIC ACCIDENT; ADOLESCENT; ADULT; AGED; COHORT ANALYSIS; EMERGENCY; EMERGENCY HEALTH SERVICE; FEMALE; GENETICS; MALE; MIDDLE AGED; OUTCOME ASSESSMENT; PAIN; PROSPECTIVE STUDY; STATISTICAL MODEL; STATISTICS; SURVIVOR; UNITED STATES;

ACCIDENTS, TRAFFIC; ADOLESCENT; ADULT; AGED; COHORT STUDIES; EMERGENCIES; EMERGENCY SERVICE, HOSPITAL; FEMALE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; NORTH CAROLINA; OUTCOME ASSESSMENT (HEALTH CARE); PAIN; PROSPECTIVE STUDIES; STRESS DISORDERS, POST-TRAUMATIC; SURVIVORS; YOUNG ADULT;

EID: 80053359909     PISSN: None     EISSN: 1471227X     Source Type: Journal    
DOI: 10.1186/1471-227X-11-14     Document Type: Article

References (37)

1. Tang N, Stein J, Hsia RY, Maselli JH, Gonzales R. Trends and characteristics of US emergency department visits, 1997-2007. JAMA 304(6):664-670.
2. Medicaid beneficiaries and access to care. Kaiser Commission on Medicaid and the Uninsured, Kaiser Family Foundation. , http://www.kff.org/medicaid/upload/8000-02.pdf
3. Maio RF, Shope JT, Blow FC, Gregor MA, Zakrajsek JS, Weber JE, Nypaver MM. A Randomized Controlled Trial of an Emergency Department-Based Interactive Computer Program to Prevent Alcohol Misuse Among Injured Adolescents. Annals of Emergency Medicine 2005, 45(4):420-429. 10.1016/j.annemergmed.2004.10.013, 15795723.
4. Walton MA, Chermack ST, Shope JT, Bingham CR, Zimmerman MA, Blow FC, Cunningham RM. Effects of a Brief Intervention for Reducing Violence and Alcohol Misuse Among Adolescents. Journal of the American Medical Association 2010, 304(5):527-535. 10.1001/jama.2010.1066, 20682932.
5. Kline JA, Courtney DM, Kabrhel C, Moore CL, Smithline HA, Plewa MC, Richman PB, O'Neil BJ, Nordenholz K. Prospective multicenter evaluation of the pulmonary embolism rule-out criteria. J Thromb Haemost 2008, 6(5):772-780. 10.1111/j.1538-7836.2008.02944.x, 18318689.
6. Courtney DM, Kline JA, Kabrhel C, Moore CL, Smithline HA, Nordenholz KE, Richman PB, Plewa MC. Clinical features from the history and physical examination that predict the presence or absence of pulmonary embolism in symptomatic emergency department patients: results of a prospective, multicenter study. Annals of Emergency Medicine 2010, 56(5).
7. Haukoos JS, Hopkins E, Conroy AA, Silverman M, Byyny RL, Eisert S, Thrun MW, Wilson ML, Hutchinson AB, Forsyth J, et al. Routine opt-out rapid HIV screening and detection of HIV infection in emergency department patients. Journal of the American Medical Association 2010, 304(3):284-292. 10.1001/jama.2010.953, 20639562.
8. Trautman DE, McCarthy ML, Miller N, Campbell JC, Kelen GD. Intimate partner violence and emergency department screening: computerized screening versus usual care. Annals of Emergency Medicine 2007, 49(4):526-534. 10.1016/j.annemergmed.2006.11.022, 17276547.
9. Tseng YM, Hu BW, Tsai SM, IJ C, Jin YR, Lee JH, Huang FD, Wu SH, Yeh FL, Ysai LY. Distribution of alcohol-metabolizing enzyme genotypes in trauma patients with excessive alcohol consumption in the emergency department. Clin Biochem 2007, 40(5-6):370-376. 10.1016/j.clinbiochem.2006.11.012, 17292341.
10. McCaig LF. National Center for Health Statistics. 2010,
11. Hartling L, Brison RJ, Ardern C, Pickett W. Prognostic value of the Quebec Classification of Whiplash-Associated Disorders. Spine 2001, 26(1):36-41. 10.1097/00007632-200101010-00008, 11148643.
12. Suissa S, Harder S, Veilleux M. The relation between initial symptoms and signs and the prognosis of whiplash. European Spine Journal 2001, 10(1):44-49. 10.1007/s005860000220, 11276835.
13. Freeman MD, Croft AC, Rossignol AM, Weaver DS, Reiser M. A review and methodologic critique of the literature refuting whiplash syndrome. Spine 1999, 24(1):86-96. 10.1097/00007632-199901010-00022, 9921598.
14. Carroll LJ, Holm LW, Hogg-Johnson S, Cote P, Cassidy JD, Haldeman S, Nordin M, Hurwitz EL, Carragee EJ, van der Velde G, et al. Course and prognostic factors for neck pain in whiplash-associated disorders (WAD): results of the Bone and Joint Decade 2000-2010 Task Force on Neck Pain and Its Associated Disorders. Spine (Phila Pa 1976) 2008, 33(4 Suppl):S83-92.
15. McLean SA, Clauw DJ, Abelson JL, Liberzon I. The development of persistent pain and psychological morbidity after motor vehicle collision: integrating the potential role of stress response systems into a biopsychosocial model. Psychosom Med 2005, 67(5):783-790. 10.1097/01.psy.0000181276.49204.bb, 16204439.
16. Cassidy JD, Carroll LJ, Cote P, Lemstra M, Berglund A, Nygren A. Effect of eliminating compensation for pain and suffering on the outcome of insurance claims for whiplash injury. New England Journal of Medicine 2000, 342(16):1179-1186. 10.1056/NEJM200004203421606, 10770984.
17. Diatchenko L, Nackley AG, Slade GD, Belfer I, Max MB, Goldman D, Maixner W. Responses to Drs. Kim and Dionne regarding comments on Diatchenko, et al. Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli. Pain 2007, 129(3):366-370. 10.1016/j.pain.2007.02.012, 1976270, 17851590.
18. PAXgene Blood DNA Kit Handbook. PreAnalytix Company 2009,
19. The Abbreviated Injury Scale (AIS) 1990 Revision. 1990, Des Plaines, IL: Association for the Advancement of Automotive Medicine.
20. Certificate of Confidentiality. , http://grants.nih.gov/grants/policy/coc/
21. CITI Program. , https://www.citiprogram.org/default.asp?language=english
22. Nackley AG, Shabalina SA, Tchivileva IE, Satterfield K, Korchynskyi O, Makarov SS, Maixner W, Diatchenko L. Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure. Science 2006, 314(5807):1930-1933. 10.1126/science.1131262, 17185601.
23. DeMille MM, Kidd JR, Ruggeri V, Palmatier MA, Goldman D, Odunsi A, Okonofua F, Grigorenko E, Schulz LO, Bonne-Tamir B, et al. Population variation in linkage disequilibrium across the COMT gene considering promoter region and coding region variation. Hum Genet 2002, 111(6):521-537. 10.1007/s00439-002-0809-0, 12436243.
24. Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006, 38(8):904-909. 10.1038/ng1847, 16862161.
25. Wolfe F. Pain extent and diagnosis: development and validation of the regional pain scale in 12,799 patients with rheumatic disease. J Rheumatol 2003, 30(2):369-378.
26. Hirsch JK, Britton PC, Conner KR. Psychometric evaluation of the Life Orientation Test--Revised in treated opiate dependent individuals. International Journal of Mental Health and Addiction 2010, 8(3):423-431.
27. Brunet A, Weiss DS, Metzler TJ, Best SR, Neylan TC, Rogers C, Fagan J, Marmar CR. The Peritraumatic Distress Inventory: a proposed measure of PTSD criterion A2. American Journal of Psychiatry 2001, 158(9):1480-1485. 10.1176/appi.ajp.158.9.1480, 11532735.
28. Michaels AJ, Michaels CE, Moon CH, Smith JS, Zimmerman MA, Taheri PA, Peterson C. Posttraumatic stress disorder after injury: impact on general health outcome and early risk assessment. Journal of Trauma-Injury Infection & Critical Care 1999, 47(3):460-466. discussion 466-467, 10.1097/00005373-199909000-00005, 21610362.
29. Sullivan MJ, Bishop S, Pivik J. The Pain Catastrophizing Scale: development and validation. Psychological Assessment 1995, 7:524-532.
30. Pennebaker JW. The Psychology of Physical Symptoms. 1982, New York: Springer-Verlag.
31. Ware J, Kosinski M, Keller SD. SF-12: A 12-item Short-Form Health Survey: Construction of scales and preliminary tests of reliability and validity. Medical Care 1996, 34:220-233. 10.1097/00005650-199603000-00003, 8628042.
32. Spielberger CD. Preliminary manual for the State - Trait Personality Inventory (STPI). 2000,
33. Radloff LS. The CES-D Scale: A self-report depression scale for research in the general population. Applied Psychological Measurement 1977, 1:385-401.
34. Weiss D. Psychometric review of the Impact of Event Scale-Revised. 1996, Lutherville, Maryland: Sidran Press.
35. Cherpitel CJ. Screening for alcohol problems in the emergency room: a rapid alcohol problems screen. Drug & Alcohol Dependence 1995, 40(2):133-137. 10.1016/0376-8716(95)01199-4, 21954480.
36. Smith GRJ, Ross RL, KM R. Psychiatric outcomes module: Substance abuse outcomes module (SAOM). Outcomes assessment in clinical practice 1996, 85-88. Baltimore, MD: Williams & Wilkins, Sederer LI, Dickey B.
37. Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004, 20(5):309-318. 10.1097/00002508-200409000-00005, 15322437.