Genetic variation in interleukin-28B locus is associated with spontaneous clearance of HCV in children with non-1 viral genotype infection

Hepatology

Volumn 54, Issue 4, 2011, Pages 1490-1491

  Indolfi, Giuseppe ^a   Sambrotta, Melissa ^a   Moriondo, Maria ^a   Azzari, Chiara ^a   Resti, Massimo ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B ANTIGEN; INTERLEUKIN 28B; VIRUS RNA;

CAUCASIAN; CHILD; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CLINICAL DECISION MAKING; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; HEPATITIS C; HUMAN; LETTER; NON 1 VIRAL GENOTYPE INFECTION; PERSISTENT INFECTION; PREDICTOR VARIABLE; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; VIRAL CLEARANCE;

CHILD; FEMALE; GENETIC VARIATION; GENOTYPE; HEPACIVIRUS; HEPATITIS C; HUMANS; INTERLEUKINS; LOCUS CONTROL REGION; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; REMISSION, SPONTANEOUS; RNA, VIRAL; SAMPLING STUDIES; VIRAL LOAD;

EID: 80053336295     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24482     Document Type: Letter

References (4)

1. Ruiz-Extremera A, Muñoz-Gámez J, Salmerón-Ruiz MA, de Rueda PM, Quiles-Pérez R, Gila-Medina A, et al. Genetic variation in IL28B with respect to vertical transmission of hepatitis C virus and spontaneous clearance in HCV infected children. HEPATOLOGY 2011; 53: 1830-1838.
2. Bortolotti F, Verucchi G, Cammà C, Cabibbo G, Zancan L, Indolfi G, et al. Long-term course of chronic hepatitis C in children: from viral clearance to end-stage liver disease. Gastroenterology 2008; 134: 1900-1907.
3. Resti M, Jara P, Hierro L, Azzari C, Giacchino R, Zuin G, et al. Clinical features and progression of perinatally acquired hepatitis C virus infection. J Med Virol 2003; 70: 373-377.
4. Resti M, Bortolotti F, Vajro P, Maggiore G; Committee of Hepatology of the Italian Society of Pediatric Gastroenterology and Hepatology. Guidelines for the screening and follow-up of infants born to anti-HCV positive mothers. Dig Liver Dis 2003; 35: 453-457.