Early perfusion of a free RPE-choroid graft in patients with exudative macular degeneration can be imaged with spectral domain-OCT

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 8, 2011, Pages 5881-5886

  van Zeeburg, Elsbeth J T ^a,b   Cereda, Matteo G ^b,c   van der Schoot, Josine ^a,b   Pertile, Grazia ^c   van Meurs, Jan C ^b,d  

^a Rotterdam Ophthalmic Institute   (Netherlands)

^b ROTTERDAM EYE HOSPITAL   (Netherlands)

^c SACRO CUORE DON CALABRIA HOSPITAL   (Italy)

^d ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CHOROID; CLINICAL ARTICLE; CLINICAL TRIAL; EXUDATIVE MACULAR DEGENERATION; FEMALE; FLUORESCENCE ANGIOGRAPHY; GRAFT PERFUSION; HUMAN; INDOCYANINE GREEN ANGIOGRAPHY; MALE; MULTICENTER STUDY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; REVASCULARIZATION; SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY; EXUDATE; METHODOLOGY; MIDDLE AGED; OPTICAL COHERENCE TOMOGRAPHY; PATHOLOGY; PROSPECTIVE STUDY; RETINA MACULA DEGENERATION; TRANSPLANTATION;

COLORING AGENT; DIAGNOSTIC AGENT; INDOCYANINE GREEN;

AGED; AGED, 80 AND OVER; CHOROID; COLORING AGENTS; EXUDATES AND TRANSUDATES; FEMALE; FLUORESCEIN ANGIOGRAPHY; HUMANS; INDOCYANINE GREEN; MACULAR DEGENERATION; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RETINAL PIGMENT EPITHELIUM; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 80053333470     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-7245     Document Type: Article

References (27)

1. Augood CA, Vingerling JR, de Jong PT, et al. Prevalence of agerelated maculopathy in older Europeans: the European Eye Study (EUREYE). Arch Ophthalmol. 2006;124:529-535.
2. Resnikoff S, Pascolini D, Etya'ale D, et al. Global data on visual impairment in the year 2002. Bull World Health Organ. 2004;82: 844-851.
3. Gass JD. Biomicroscopic and histopathologic considerations regarding the feasibility of surgical excision of subfoveal neovascular membranes. Am J Ophthalmol. 1994;118:285-298.
4. Grossniklaus HE, Green WR. Choroidal neovascularization. Am J Ophthalmol. 2004;137:496-503.
5. Glatt H, Machemer R. Experimental subretinal hemorrhage in rabbits. Am J Ophthalmol. 1982;94:762-773.
6. Gillies A, Lahav M. Absorption of retinal and subretinal hemorrhages. Ann Ophthalmol. 1983;15:1068-1074.
7. Rosenfeld PJ, Brown DM, Heier JS, et al. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med. 2006;355: 1419-1431.
8. Brown DM, Michels M, Kaiser PK, Heier JS, Sy JP, Ianchulev T. Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: two-year results of the ANCHOR study. Ophthalmology. 2009;116:57-65.
9. Rosenfeld PJ, Shapiro H, Tuomi L, Webster M, Elledge J, Blodi B. Characteristics of patients losing vision after 2 years of monthly dosing in the phase III ranibizumab clinical trials. Ophthalmology. 2011;118:523-530.
10. Forooghian F, Cukras C, Meyerle CB, Chew EY, Wong WT. Tachyphylaxis after intravitreal bevacizumab for exudative age-related macular degeneration. Retina. 2009;29:723-731.
11. Gelisken F, Ziemssen F, Voelker M, Bartz-Schmidt KU, Inhoffen W. Retinal pigment epithelial tears after single administration of intravitreal bevacizumab for neovascular age-related macular degeneration. Eye. 2009;23:694-702.
12. Sacu S, Stifter E, Vecsei-Marlovits PV, et al. Management of extensive subfoveal haemorrhage secondary to neovascular age-related macular degeneration. Eye. 2009;23:1404-1410.
13. Smith BT, Kraus CL, Apte RS. Retinal pigment epithelial tears in ranibizumab-treated eyes. Retina. 2009;29:335-339.
14. Bressler NM, Bressler SB, Childs AL, et al. Surgery for hemorrhagic choroidal neovascular lesions of age-related macular degeneration: ophthalmic findings: SST report no. 13. Ophthalmology. 2004;111: 1993-2006.
15. Machemer R, Steinhorst UH. Retinal separation, retinotomy, and macular relocation: II. A surgical approach for age-related macular degeneration? Graefes Arch Clin Exp Ophthalmol. 1993;231:635-641.
16. Peyman GA, Blinder KJ, Paris CL, Alturki W, Nelson NC Jr, Desai U. A technique for retinal pigment epithelium transplantation for age-related macular degeneration secondary to extensive subfoveal scarring. Ophthalmic Surg. 1991;22:102-108.
17. Maaijwee KJ, van Meurs JC, Kirchhof B, et al. Histological evidence for revascularisation of an autologous retinal pigment epithelium-choroid graft in the pig. Br J Ophthalmol. 2007;91:546-550.
18. Caramoy A, Liakopoulos S, Menrath E, Kirchhof B. Autologous translocation of choroid and retinal pigment epithelium in geographic atrophy: long-term functional and anatomical outcome. Br J Ophthalmol. 2010;94:1040-1044.
19. Cereda MG, Parolini B, Bellesini E, Pertile G. Surgery for CNV and autologous choroidal RPE patch transplantation: exposing the submacular space. Graefes Arch Clin Exp Ophthalmol. 2010;248:37-47.
20. Maaijwee K, van den Biesen PR, Missotten T, van Meurs JC. Angiographic evidence for revascularization of an rpe-choroid graft in patients with age-related macular degeneration. Retina. 2008;28:498-503.
21. Hillenkamp J, Surguch V, Framme C, Gabel VP, Sachs HG. Management of submacular hemorrhage with intravitreal versus subretinal injection of recombinant tissue plasminogen activator. Graefes Arch Clin Exp Ophthalmol. 2010;248:5-11.
22. Treumer F, Klatt C, Roider J, Hillenkamp J. Subretinal coapplication of recombinant tissue plasminogen activator and bevacizumab for neovascular age-related macular degeneration with submacular haemorrhage. Br J Ophthalmol. 2010;94:48-53.
23. van Meurs JC, van den Biesen PR. Autologous retinal pigment epithelium and choroid translocation in patients with exudative age-related macular degeneration: short-term follow-up. Am J Ophthalmol. 2003;136:688-695.
24. Pertile G, Claes C. Macular translocation with 360 degree retinotomy for management of age-related macular degeneration with subfoveal choroidal neovascularization. Am J Ophthalmol. 2002;134:560-565.
25. Converse JM, Rapaport FT. The vascularization of skin autografts and homografts; an experimental study in man. Ann Surg. 1956;143:306-315.
26. Young CM. The revascularization of pedicle skin flaps in pigs: a functional and morphologic study. Plast Reconstr Surg. 1982;70: 455-464.
27. van Zeeburg EJT, Maaijwee KJM, Missotten TOAR, Heimann H, van Meurs JC. A free retinal pigment epithelium-choroid graft in patients with exudative age-related macular degeneration; results up to seven years. Am J Ophthalmol. In press.