Resurgent Na+ current: A new avenue to neuronal excitability control

Life Sciences

Volumn 89, Issue 15-16, 2011, Pages 564-569

  Cruz, Jader S ^b   Silva, Darizy F ^a   Ribeiro, Luciano A ^a   Araújo, Islânia G A ^a   Magalhães, Nayara ^a   Medeiros, Alessandra ^a   Freitas, Christiane ^b   Araujo, Izabella C ^b   Oliveira, Fernando A ^b  

^a FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Neurons; Resurgent sodium current; Voltage gated sodium channels

Indexed keywords

CATION; SODIUM; SODIUM CHANNEL BLOCKING AGENT; SODIUM CHANNEL NAV1.6; VOLTAGE GATED SODIUM CHANNEL;

ACTION POTENTIAL; ATAXIA; CONFERENCE PAPER; DYSTONIA; HIPPOCAMPUS POTENTIAL; INTRACELLULAR SIGNALING; MEMBRANE DEPOLARIZATION; MOLECULAR DYNAMICS; NERVE CELL EXCITABILITY; NERVE CELL NETWORK; NERVE CELL STIMULATION; OSCILLATORY POTENTIAL; PURKINJE FIBER; REPOLARIZATION; RESURGENT SODIUM CURRENT; SIGNAL TRANSDUCTION; SODIUM CURRENT; SODIUM TRANSPORT; TREMOR;

ANIMALS; ELECTROPHYSIOLOGICAL PHENOMENA; HUMANS; ION CHANNEL GATING; NERVE TISSUE PROTEINS; NEURONS; PATCH-CLAMP TECHNIQUES; SODIUM CHANNELS;

EID: 80053321000     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.05.016     Document Type: Conference Paper

References (52)

1. F.S. Afshari, K. Ptak, Z.M. Khaliq, T.M. Grieco, N.T. Slater, D.R. McCrimmon, and I.M. Raman Resurgent Na currents in four classes of neurons of the cerebellum J Neurophysiol 92 2004 2831 2843 (Pubitemid 40340494)
2. C.M. Armstrong, and R.S. Croop Simulation of Na channel inactivation by thiazine dyes J Gen Physiol 80 1982 641 662 (Pubitemid 13202073)
3. J.S. Bant, and I.M. Raman Control of transient, resurgent, and persistent current by open-channel block by Na channel beta4 in cultured cerebellar granule neurons Proc Natl Acad Sci U S A 107 2010 12357 12362
4. F. Bezanilla, and C.M. Armstrong Inactivation of the sodium channel. I. Sodium current experiments J Gen Physiol 70 1977 549 566 (Pubitemid 8239321)
5. D. Bowie, and M.L. Mayer Inward rectification of both AMPA and kainate subtype glutamate receptors generated by polyamine-mediated ion channel block Neuron 15 1995 453 462
6. S.A. Burbidge, T.J. Dale, A.J. Powell, W.R. Whitaker, X.M. Xie, M.A. Romanos, and J.J. Clare Molecular cloning, distribution and functional analysis of the NA(V)1.6. Voltage-gated sodium channel from human brain Brain Res Mol Brain Res 103 2002 80 90 (Pubitemid 34775036)
7. L. Castelli, M.J. Nigro, and J. Magistretti Analysis of resurgent sodium-current expression in rat parahippocampal cortices and hippocampal formation Brain Res 1163 2007 44 55 (Pubitemid 47125860)
8. W.A. Catterall From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels Neuron 26 2000 13 25
9. W.A. Catterall Signaling complexes of voltage-gated sodium and calcium channels Neurosci Lett 486 2010 107 116
10. M. Chahine, R. Ziane, K. Vijayaragavan, and Y. Okamura Regulation of Na v channels in sensory neurons Trends Pharmacol Sci 26 2005 496 502
11. W.E. Crill Persistent sodium current in mammalian central neurons Annu Rev Physiol 58 1996 349 362 (Pubitemid 26106725)
12. v1.6 channels generate resurgent sodium currents in spinal sensory neurons FEBS Lett 579 2005 2166 2170 (Pubitemid 40469688)
13. +-dependent mechanism J Neurosci 21 2001 759 770 (Pubitemid 32163117)
14. M.T. Do, and B.P. Bean Subthreshold sodium currents and pacemaking of subthalamic neurons: modulation by slow inactivation Neuron 39 2003 109 120 (Pubitemid 36830952)
15. P.A. Felts, S. Yokoyama, S. Dib-Hajj, J.A. Black, and S.G. Waxman Sodium channel alpha-subunit mRNAs I, II, III, NaG, Na6 and hNE (PN1): different expression patterns in developing rat nervous system Brain Res Mol Brain Res 45 1997 71 82 (Pubitemid 27182226)
16. M. Fry Developmental expression of Na + currents in mouse Purkinje neurons Eur J Neurosci 24 2006 2557 2566 (Pubitemid 44726767)
17. A.H. Gittis, and S. du Lac Similar properties of transient, persistent, and resurgent Na currents in GABAergic and non-GABAergic vestibular nucleus neurons J Neurophysiol 99 2008 2060 2065
18. A.L. Goldin, R.L. Barchi, J.H. Caldwell, F. Hofmann, J.R. Howe, J.C. Hunter, R.G. Kallen, G. Mandel, M.H. Meisler, Y.B. Netter, M. Noda, M.M. Tamkun, S.G. Waxman, J.N. Wood, and W.A. Catterall Nomenclature of voltage-gated sodium channels Neuron 28 2000 365 368
19. T.M. Grieco, and I.M. Raman Production of resurgent current in NaV1.6-null Purkinje neurons by slowing sodium channel inactivation with beta-pompilidotoxin J Neurosci 24 2004 35 42 (Pubitemid 38181667)
20. T.M. Grieco, F.S. Afshari, and I.M. Raman A role for phosphorylation in the maintenance of resurgent sodium current in cerebellar purkinje neurons J Neurosci 22 2002 3100 3107 (Pubitemid 35379199)
21. T.M. Grieco, J.D. Malhotra, C. Chen, L.L. Isom, and I.M. Raman Open-channel block by the cytoplasmic tail of sodium channel beta4 as a mechanism for resurgent sodium current Neuron 45 2005 233 244 (Pubitemid 40128117)
22. + channels Science 289 2000 123 127 (Pubitemid 30463306)
23. H.A. Hartmann, L.V. Colom, M.L. Sutherland, and J.L. Noebels Selective localization of cardiac SCN5A sodium channels in limbic regions of rat brain Nat Neurosci 2 1999 593 595 (Pubitemid 30491207)
24. M. Hausser, I.M. Raman, T. Otis, S.L. Smith, A. Nelson, S. du Lac, Y. Loewenstein, S. Mahon, C. Pennartz, I. Cohen, and Y. Yarom The beat goes on: spontaneous firing in mammalian neuronal microcircuits J Neurosci 24 2004 9215 9219 (Pubitemid 39426154)
25. A.L. Hodgkin, and A.F. Huxley A quantitative description of membrane current and its application to conduction and excitation in nerve J Physiol 117 1952 500 544
26. T. Hoshi, W.N. Zagotta, and R.W. Aldrich Biophysical and molecular mechanisms of Shaker potassium channel inactivation Science 250 1990 533 538 (Pubitemid 120031778)
27. Z.M. Khaliq, N.W. Gouwens, and I.M. Raman The contribution of resurgent sodium current to high-frequency firing in Purkinje neurons: an experimental and modeling study J Neurosci 23 2003 4899 4912 (Pubitemid 36793216)
28. J.H. Kim, C. Kushmerick, and H. von Gersdorff Presynaptic resurgent Na + currents sculpt the action potential waveform and increase firing reliability at a CNS nerve terminal J Neurosci 30 2010 15479 15490
29. + channels must deactivate to recover from inactivation Neuron 12 1994 819 829 (Pubitemid 24126243)
30. R.R. Llinas The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function Science 242 1988 1654 1664 (Pubitemid 19022170)
31. R. Llinas, and M. Sugimori Electrophysiological properties of in vitro Purkinje cell dendrites in mammalian cerebellar slices J Physiol 305 1980 197 213 (Pubitemid 10048156)
32. J. Magistretti, L. Castelli, L. Forti, and E. D'Angelo Kinetic and functional analysis of transient, persistent and resurgent sodium currents in rat cerebellar granule cells in situ: an electrophysiological and modelling study J Physiol 573 2006 83 106 (Pubitemid 43670860)
33. L.M. Masukawa, A.J. Hansen, and G. Shepherd Distribution of single-channel conductances in cultured rat hippocampal neurons Cell Mol Neurobiol 11 1991 231 243
34. M.H. Meisler, and J.A. Kearney Sodium channel mutations in epilepsy and other neurological disorders J Clin Invest 115 2005 2010 2017 (Pubitemid 41134136)
35. v1.6 sodium channels are critical to pacemaking and fast spiking in globus pallidus neurons J Neurosci 27 2007 13552 13566 (Pubitemid 350255328)
36. L. Nowak, P. Bregestovski, P. Ascher, A. Herbet, and A. Prochiantz Magnesium gates glutamate-activated channels in mouse central neurones Nature 307 1984 462 465 (Pubitemid 14132062)
37. + channels Jpn J Pharmacol 88 2002 365 377 (Pubitemid 34520379)
38. M.E. O'Leary, and R. Horn Internal block of human heart sodium channels by symmetrical tetra-alkylammoniums J Gen Physiol 104 1994 507 522
39. F. Pan, and K.G. Beam The absence of resurgent sodium current in mouse spinal neurons Brain Res 849 1999 162 168
40. D.E. Patton, J.W. West, W.A. Catterall, and A.L. Goldin Amino acid residues required for fast Na(+)-channel inactivation: charge neutralizations and deletions in the III-IV linker Proc Natl Acad Sci U S A 89 1992 10905 10909
41. I.M. Raman, and B.P. Bean Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons J Neurosci 17 1997 4517 4526 (Pubitemid 27246909)
42. I.M. Raman, and B.P. Bean Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons J Neurosci 19 1999 1663 1674 (Pubitemid 29094185)
43. I.M. Raman, and B.P. Bean Inactivation and recovery of sodium currents in cerebellar Purkinje neurons: evidence for two mechanisms Biophys J 80 2001 729 737 (Pubitemid 32128326)
44. I.M. Raman, L.K. Sprunger, M.H. Meisler, and B.P. Bean Altered subthreshold sodium currents and disrupted firing patterns in Purkinje neurons of Scn8a mutant mice Neuron 19 1997 881 891 (Pubitemid 27471392)
45. + channels altered by presence of beta-subunit Nature 369 1994 289 294 (Pubitemid 24159535)
46. v1.6 channel. Significance in mice Purkinje neurons J Biol Chem 281 2006 20326 20337 (Pubitemid 44065807)
47. M.R. Smith, R.D. Smith, N.W. Plummer, M.H. Meisler, and A.L. Goldin Functional analysis of the mouse Scn8a sodium channel J Neurosci 18 1998 6093 6102 (Pubitemid 28373218)
48. + channels: a transmembrane beta-subunit homolog Proc Natl Acad Sci U S A 96 1999 4137 4142 (Pubitemid 29169049)
49. J.W. West, D.E. Patton, T. Scheuer, Y. Wang, A.L. Goldin, and W.A. Catterall A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation Proc Natl Acad Sci U S A 89 1992 10910 10914
50. v1.5 sodium channel protein in the mouse brain Neuroreport 13 2002 2547 2551 (Pubitemid 36143560)
51. F.H. Yu, R.E. Westenbroek, I. Silos-Santiago, K.A. McCormick, D. Lawson, P. Ge, H. Ferriera, J. Lilly, P.S. DiStefano, W.A. Catterall, T. Scheuer, and R. Curtis Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2 J Neurosci 23 20 2003 7577 7585 (Pubitemid 37034074)
52. G.W. Zamponi, and R.J. French Open-channel block by internally applied amines inhibits activation gate closure in batrachotoxin-activated sodium channels Biophys J 67 1994 1040 1051 (Pubitemid 24272953)