Dysmegakaryopoiesis, a clue for an early diagnosis of familial platelet disorder with propensity to acute myeloid leukemia in case of unexplained inherited thrombocytopenia associated with normal-sized platelets

Journal of Pediatric Hematology/Oncology

Volumn 33, Issue 7, 2011, Pages

  Latger Cannard, Véronique ^a,c   Philippe, Christophe ^b   Jonveaux, Philippe ^b   Lecompte, Thomas ^a,c   Favier, Rémi ^c,d,e  

^a UNIVERSITY HOSPITAL OF NANCY   (France)

^b UNIVERSITÉ DE LORRAINE   (France)

^c ARMAND TROUSSEAU HOSPITAL   (France)

^d INSERM   (France)

^e Centre de Référence des Pathologies Plaquettaires   (France)

Author keywords

dysmegakaryopoiesis; familial platelet disorder with predisposition to acute myeloid leukaemia; platelet; RUNX1 gene

Indexed keywords

CD63 ANTIGEN; MESSENGER RNA; TRANSCRIPTION FACTOR RUNX1;

ACUTE GRANULOCYTIC LEUKEMIA; AMINO TERMINAL SEQUENCE; ANOREXIA; ANTIGEN EXPRESSION; ARTICLE; ASTHENIA; BLEEDING; BONE MARROW BIOPSY; BONE MARROW EXAMINATION; BONE MARROW TRANSPLANTATION; CASE REPORT; CELL SIZE; CHILD; DYSMEGAKARYOPOIESIS; EARLY DIAGNOSIS; FAMILIAL DISEASE; FLOW CYTOMETRY; FRAMESHIFT MUTATION; GENE DELETION; GENETIC PREDISPOSITION; HEMATOLOGIC DISEASE; HUMAN; HUMAN TISSUE; LABORATORY TEST; MALE; MEGAKARYOCYTE; NONSENSE MEDIATED MRNA DECAY; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; PURPURA; SKIN BRUISING; STEM CELL TRANSPLANTATION; STOP CODON; THROMBOCYTE DISORDER; THROMBOCYTE SIZE; THROMBOCYTOPENIA;

BLOOD PLATELET DISORDERS; BLOOD PLATELETS; CHILD, PRESCHOOL; CORE BINDING FACTOR ALPHA 2 SUBUNIT; FAMILY; HUMANS; LEUKEMIA, MYELOID, ACUTE; MALE; MEGAKARYOCYTES; PEDIGREE; THROMBOCYTOPENIA;

EID: 80053299225     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e31821754ac     Document Type: Article

References (8)

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