Reproductive Hormones and the Menopause Transition

Obstetrics and Gynecology Clinics of North America

Volumn 38, Issue 3, 2011, Pages 455-466

  Santoro, Nanette ^a   Randolph, John F ^b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Anti Mullerian hormone; Estrogen; Follicle stimulating hormone; Inhibin; Luteinizing hormone; Menopause; Menopause transition; Progesterone

Indexed keywords

ANDROGEN; ESTRADIOL; ESTROGEN; FOLLITROPIN; INHIBIN B; LUTEINIZING HORMONE; MUELLERIAN INHIBITING FACTOR; PROGESTERONE; REPRODUCTIVE HORMONE; SEX HORMONE; UNCLASSIFIED DRUG;

BLEEDING; BODY MASS; CLIMACTERIUM; ETHNICITY; FOLLICULAR PHASE; HORMONE ACTION; HORMONE BLOOD LEVEL; HORMONE RELEASE; HUMAN; MENOPAUSE; MENSTRUAL CYCLE; OVARY FOLLICLE; OVULATION; POSTMENOPAUSE; PRIORITY JOURNAL; RACE; REPRODUCTION; REVIEW; SLEEP; WOMEN'S HEALTH;

BODY MASS INDEX; FEMALE; HEALTH SURVEYS; HORMONES; HUMANS; MENSTRUAL CYCLE; PERIMENOPAUSE; UNITED STATES;

EID: 80053291471     PISSN: 08898545     EISSN: 15580474     Source Type: Journal    
DOI: 10.1016/j.ogc.2011.05.004     Document Type: Review

References (47)

1. Block E. Quantitative morphological investigations of the follicular system in women; variations at different ages. Acta Anat (Basel) 1952, 14:108.
2. Baker T.G. A quantitative and cytological study of germ cells in human ovaries. Proc R Soc Lond B Biol Sci 1963, 158:417.
3. Faddy M.J., Gosden R.G., Gougeon A., et al. Accelerated disappearance of ovarian follicles in mid-life: implications for forecasting menopause. Hum Reprod 1992, 7:1342.
4. Richardson S.J., Senikas V., Nelson J.F. Follicular depletion during the menopausal transition: evidence for accelerated loss and ultimate exhaustion. J Clin Endocrinol Metab 1987, 65:1231.
5. Battaglia D.E., Goodwin P., Klein N.A., et al. Influence of maternal age on meiotic spindle assembly in oocytes from naturally cycling women. Hum Reprod 1996, 11:2217.
6. Klein N.A., Battaglia D.E., Miller P.B., et al. Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age. J Clin Endocrinol Metab 1996, 81:1946.
7. Santoro N., Isaac B., Neal-Perry G., et al. Impaired folliculogenesis and ovulation in older reproductive aged women. J Clin Endocrinol Metab 2003, 88:5502.
8. Weiss G., Skurnick J.H., Goldsmith L.T., et al. Menopause and hypothalamic-pituitary sensitivity to estrogen. JAMA 2004, 292:2991.
9. Sowers M.F., Crawford S.L., Sternfeld B., et al. SWAN: a multi-center, multi-ethnic, community-based cohort study of women and the menopausal transition. Menopause: biology and pathobiology 2000, 175. Academic Press, San Diego. R.A. Lobo, J. Kelsey, R. Marcus (Eds.).
10. Ahmed Ebbiary N.A., Lenton E.A., Cooke I.D. Hypothalamic-pituitary ageing: progressive increase in FSH and LH concentrations throughout the reproductive life in regularly menstruating women. Clin Endocrinol (Oxf) 1994, 41:199.
11. Harlow S.D., Mitchell E.S., Crawford S., et al. The ReSTAGE Collaboration: defining optimal bleeding criteria for onset of early menopausal transition. Fertil Steril 2008, 89:129.
12. Randolph J.F., Zheng H., Sowers M.R., et al. Change in follicle-stimulating hormone and estradiol across the menopausal transition: effect of age at the final menstrual period. J Clin Endocrinol Metab 2011, 96:746-754.
13. Santoro N., Brockwell S., Johnston J., et al. Helping midlife women predict the onset of the final menses: SWAN, the Study of Women's Health Across the Nation. Menopause 2007, 14:415.
14. Santoro N., Brown J.R., Adel T., et al. Characterization of reproductive hormonal dynamics in the perimenopause. J Clin Endocrinol Metab 1996, 81:1495.
15. Finkelstein J.S., Brockwell S.E., Mehta V., et al. Bone mineral density changes during the menopause transition in a multiethnic cohort of women. J Clin Endocrinol Metab 2008, 93:861.
16. Danforth D.R., Arbogast L.K., Mroueh J., et al. Dimeric inhibin: a direct marker of ovarian aging. Fertil Steril 1998, 70:119.
17. Seifer D.B., Lambert-Messerlian G., Hogan J.W., et al. Day 3 serum inhibin-B is predictive of assisted reproductive technologies outcome. Fertil Steril 1997, 67:110.
18. Sowers M.R., Eyvazzadeh A.D., McConnell D., et al. Anti-mullerian hormone and inhibin B in the definition of ovarian aging and the menopause transition. J Clin Endocrinol Metab 2008, 93:3478.
19. McKinlay S.M. The normal menopause transition: an overview. Maturitas 1996, 23:137.
20. Burger H.G. The endocrinology of the menopause. J Steroid Biochem Mol Biol 1999, 69:31.
21. Randolph J.F., Sowers M., Bondarenko I.V., et al. Change in estradiol and follicle-stimulating hormone across the early menopausal transition: effects of ethnicity and age. J Clin Endocrinol Metab 2004, 89:1555.
22. Randolph J.F., Zheng H., Sowers M.R., et al. Change in follicle-stimulating hormone and estradiol across the menopausal transition: effect of age at the final menstrual period. J Clin Endocrinol Metab 2011, 96:746.
23. Sowers M.R., Zheng H., McConnell D., et al. Follicle stimulating hormone and its rate of change in defining menopause transition stages. J Clin Endocrinol Metab 2008, 93:3958.
24. Burger H.G., Cahir N., Robertson D.M., et al. Serum inhibins A and B fall differentially as FSH rises in perimenopausal women. Clin Endocrinol (Oxf) 1998, 48:809.
25. Wallace R.B., Sherman B.M., Bean J.A., et al. Probability of menopause with increasing duration of amenorrhea in middle-aged women. Am J Obstet Gynecol 1979, 135:1021.
26. Burger H.G., Hale G.E., Robertson D.M., et al. A review of hormonal changes during the menopausal transition: focus on findings from the Melbourne Women's Midlife Health Project. Hum Reprod Update 2007, 13:559.
27. Freeman E.W., Sammel M.D., Gracia C.R., et al. Follicular phase hormone levels and menstrual bleeding status in the approach to menopause. Fertil Steril 2005, 83:383.
28. Metcalf M.G. The approach of menopause: a New Zealand study. N Z Med J 1988, 101:103.
29. Metcalf M.G., Donald R.A., Livesey J.H. Classification of menstrual cycles in pre- and perimenopausal women. J Endocrinol 1981, 91:1.
30. Metcalf M.G., Donald R.A., Livesey J.H. Pituitary-ovarian function before, during and after the menopause: a longitudinal study. Clin Endocrinol (Oxf) 1982, 17:489.
31. Metcalf M.G., Donald R.A., Livesey J.H. Pituitary-ovarian function in normal women during the menopausal transition. Clin Endocrinol (Oxf) 1981, 14:245.
32. Metcalf M.G., Livesey J.H. Gonadotrophin excretion in fertile women: effect of age and the onset of the menopausal transition. J Endocrinol 1985, 105:357.
33. Santoro N., Lasley B., McConnell D., et al. Body size and ethnicity are associated with menstrual cycle alterations in women in the early menopausal transition: The Study of Women's Health across the Nation (SWAN) Daily Hormone Study. J Clin Endocrinol Metab 2004, 89:2622.
34. O'Connor K.A., Ferrell R.J., Brindle E., et al. Total and unopposed estrogen exposure across stages of the transition to menopause. Cancer Epidemiol Biomarkers Prev 2009, 18:828.
35. Hale G.E., Hughes C.L., Burger H.G., et al. Atypical estradiol secretion and ovulation patterns caused by luteal out-of-phase (LOOP) events underlying irregular ovulatory menstrual cycles in the menopausal transition. Menopause 2009, 16:50.
36. Burger H.G., Dudley E.C., Cui J., et al. A prospective longitudinal study of serum testosterone, dehydroepiandrosterone sulfate, and sex hormone-binding globulin levels through the menopause transition. J Clin Endocrinol Metab 2000, 85:2832.
37. Quinkler M., Sinha B., Tomlinson J.W., et al. Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5. J Endocrinol 2004, 183:331.
38. Torrens J.I., Sutton-Tyrrell K., Zhao X., et al. Relative androgen excess during the menopausal transition predicts incident metabolic syndrome in midlife women: study of Women's Health Across the Nation. Menopause 2009, 16:257.
39. Lasley B.L., Santoro N., Randolf J.F., et al. The relationship of circulating dehydroepiandrosterone, testosterone, and estradiol to stages of the menopausal transition and ethnicity. J Clin Endocrinol Metab 2002, 87:3760.
40. Crawford S., Santoro N., Laughlin G.A., et al. Circulating dehydroepiandrosterone sulfate concentrations during the menopausal transition. J Clin Endocrinol Metab 2009, 94:2945.
41. Santoro N., Torrens J., Crawford S., et al. Correlates of circulating androgens in mid-life women: the study of women's health across the nation. J Clin Endocrinol Metab 2005, 90:4836.
42. Van Voorhis B.J., Santoro N., Harlow S., et al. The relationship of bleeding patterns to daily reproductive hormones in women approaching menopause. Obstet Gynecol 2008, 112:101.
43. Kravitz H.M., Janssen I., Santoro N., et al. Relationship of day-to-day reproductive hormone levels to sleep in midlife women. Arch Intern Med 2005, 165:2370.
44. Matthews K.A., Santoro N., Lasley B., et al. Relation of cardiovascular risk factors in women approaching menopause to menstrual cycle characteristics and reproductive hormones in the follicular and luteal phases. J Clin Endocrinol Metab 2006, 91:1789.
45. Matthews K.A., Crawford S.L., Chae C.U., et al. Are changes in cardiovascular disease risk factors in midlife women due to chronological aging or to the menopausal transition?. J Am Coll Cardiol 2009, 54:2366.
46. Randolph J.F., Sowers M., Gold E.B., et al. Reproductive hormones in the early menopausal transition: relationship to ethnicity, body size, and menopausal status. J Clin Endocrinol Metab 2003, 88:1516.
47. Sowers M., Zheng H., Tomey K., et al. Changes in body composition in women over six years at midlife: ovarian and chronological aging. J Clin Endocrinol Metab 2007, 92:895.