Homology modeling and functional testing of an ABCA1 mutation causing Tangier disease

Atherosclerosis

Volumn 218, Issue 2, 2011, Pages 404-410

  Suetani, Rachel J ^a   Sorrenson, Brie ^a   Tyndall, Joel D A ^a   Williams, Michael J A ^a   McCormick, Sally P A ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

ABCA1; Cholesterol efflux; HDL; Homology modeling; Tangier disease

Indexed keywords

ABC TRANSPORTER A1; CHOLESTEROL; COMPLEMENTARY DNA; MUTANT PROTEIN;

ALPHA HELIX; ARTICLE; CASE REPORT; CELL MEMBRANE; CELL STRAIN HEK293; CHOLESTEROL TRANSPORT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EXPRESSION VECTOR; FIBROBLAST; GENE MUTATION; HETEROZYGOTE; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MOLECULAR MODEL; NUCLEOTIDE BINDING DOMAIN; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN MOTIF; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; TANGIER DISEASE; TRANSIENT TRANSFECTION; WILD TYPE;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ATP-BINDING CASSETTE TRANSPORTERS; COMPUTATIONAL BIOLOGY; FIBROBLASTS; HEK293 CELLS; HETEROZYGOTE; HUMANS; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; TANGIER DISEASE;

EID: 80053287187     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2011.06.019     Document Type: Article

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