Antihyperglycemic and hypolipidemic activity of methanolic extract of Amaranthus viridis leaves in experimental diabetes

Indian Journal of Pharmacology

Volumn 43, Issue 4, 2011, Pages 450-454

  Girija, Krishnamurthy ^a   Lakshman, Kuruba ^a   Pruthvi, Nagaraj ^a   Chandrika, Pulla Udaya ^a  

^a People's Education Society   (India)

Author keywords

Amaranthus viridis; Antihyperglycemia; hypolipidemic; pancreas; streptozotocin; type 2 diabetes

Indexed keywords

AMARANTHUS VIRIDIS EXTRACT; ANTILIPEMIC AGENT; CHOLESTEROL; GLIBENCLAMIDE; GLUCOSE; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PLANT EXTRACT; STREPTOZOCIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

AMARANTHUS; AMARANTHUS VIRIDIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HYPERLIPIDEMIA; LIPOPROTEIN BLOOD LEVEL; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; RAT; TREATMENT RESPONSE; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 80053286856     PISSN: 02537613     EISSN: 19983751     Source Type: Journal    
DOI: 10.4103/0253-7613.83120     Document Type: Article

References (21)

1. Haffner SM. The insulin resistance syndrome revisited. Diabetic core 1996;19:275-7. (Pubitemid 26070356)
2. Lamer J. The pharmacological basis of therapeutics. 7th ed. New York: Macmillan; 1985. p. 1490.
3. The Wealth of India, Raw Materis Revised edition, Vol 1A, New Delhi: Publication and Information Directorate; 1996.
4. Bressani B, Garcia-Vela LA. Influence of nitrogen applications on protein and aminoacids profiles of Amaranth and Quinoa. J Agri Food Chem 1990;38:1205-9.
5. Bruni R, Medici A, Guerrrini A, Scalia S, Poli F, Muzzoli M. Wild Amaranthus caudatus seed oil: A nutraceutical resource from Ecuadorian flora. J Agri Food Chem 2000;49:5455-60. (Pubitemid 33089692)
6. Chaturvedi A, Sarojini G, Devi NE. Hypocholesterolemic effect of Amaranth seeds (A. esculatus). Plant Food Hum Nutr 2003;44:67-70.
7. Jia W, Gao W, Tang L. Antidiabetic herbal drugs officially approved in China. Phytother Res 2003;17:1127-34. (Pubitemid 38057166)
8. Harborne JB. Phytochemical methods. London: Chapman and Hall; 1998. p. 182.
9. PHS. Public health service policy on Human health care and use of laboratory animals, Washington D.C., U.S: Department of Health and Human Services; 1986.
10. Kesari AN, Gupta RK, Singh SK, Diwakar S, Watal G. Hypoglycemic and antihyperglycemic activity of Aegele marmelos seed extracts in normal and diabetic rats. J Ethnopharmacol 2006;107:374-9. (Pubitemid 44363036)
11. Kadnur SV, Goyal RK. Comparitive antidiabetic activity of methanolic extract and ethyl acetate extract of Zingiber officinale Roscoe. Indian J Pharm Sci 2005;67:453-7.
12. Kedar P, Charaborthy CH. Effect of bitter guard (Momordica charantia) seed and glibenclamide in streptozotocin induced diabetes mellitus. Indian J Exp Biol 1982;20:232-5. (Pubitemid 12113424)
13. Elsner M, Guld bake B, Tiedge M, Munday R, Lenzen S. Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin. Diabetalogia 2000;43:1528-3.
14. Kamtchouing P, Sokeng DS, Moundipa FP, Watcho P, Jatsa BH, Lontsi D. Protective role of Anacardium occidentale extract against STZ-induced diabetes in rats. J Ethnopharmacol 1998;62:55-99.
15. Chen V, Lanuzzo CD. Dosage effect of STZ on rat tissue enzyme activities and Glycogen concentration. Can J Physiol Pharmacol 1982;60:1251-6. (Pubitemid 13218548)
16. Latner A. Clinical bio chemistry. Philadelphia:,Saunders; 1958. p. 48.
17. Carini M, Adlini G, Furlanetto S, Stefani R, Facino RM. LC coupled to ion- trap MS for the rapid screening and detection of poly phenol anti-oxidants from Helichrysum stoechas. J Pharm Biomed 2001;24:517-26. (Pubitemid 32121978)
18. Czinner E, Hagymasi K, Blazovies A, Kery A, Szoke E, Lemverkovics E. In vitro anti-oxidant properties of Helichrysum arenarium (L) Moench. J Ethnopharmacol 2000;73:437-43.
19. Bierman EL, Amaral JA, Belknap BH. Hyperlipidemia and diabetes. Diabetes 1996;15: 675-9.
20. Pushparaj PN, Low HK, Manikandan J, Tan BK, Tan CH. Anti-diabetics of Cichorium intybus in STZ-induced diabetic rats. J Ethnopharmacol 2007;111:430-4. (Pubitemid 46528073)
21. Murali B, Upadhyaya UM, Goyal RK. Effect of chronic treatment with Enicostemma littorale in non-insulin dependent diabetic (NIDDM) rats. J Ethnopharmacol 2002;81:199-204. (Pubitemid 34628502)