메뉴 건너뛰기




Volumn 10, Issue 4, 2011, Pages 361-369

Anti-angiogenesis by lentivirus-mediated small interfering RNA silencing of angiopoietin-2 gene in pancreatic carcinoma

Author keywords

Angiogenesis; Angiopoietin 2; Gene therapy; Pancreatic carcinoma; RNA interference

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANGIOPOIETIN 2; BETA ACTIN; CD34 ANTIGEN; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; MESSENGER RNA; SMALL INTERFERING RNA; VASCULOTROPIN;

EID: 80053230783     PISSN: 15330346     EISSN: None     Source Type: Journal    
DOI: 10.7785/tcrt.2012.500213     Document Type: Article
Times cited : (15)

References (30)
  • 1
    • 77951755278 scopus 로고    scopus 로고
    • Pancreatic cancer
    • Hidalgo, M. Pancreatic cancer. N Engl J Med 362, 1605-1617 (2010).
    • (2010) N Engl J Med , vol.362 , pp. 1605-1617
    • Hidalgo, M.1
  • 2
  • 3
    • 51349141767 scopus 로고    scopus 로고
    • Inhibition of pancreatic carcinoma growth by adenovirus-mediated human interleukin-24 expression in animal model
    • Pan, X., Sheng, W. H., Zhu, Q. Y., Xie, Y. F., Ye, Z. M., Xiang, J., Li, D. C., Yang, J. C. Inhibition of pancreatic carcinoma growth by adenovirus-mediated human interleukin-24 expression in animal model. Cancer Biother Radio 23, 425-434 (2008).
    • (2008) Cancer Biother Radio , vol.23 , pp. 425-434
    • Pan, X.1    Sheng, W.H.2    Zhu, Q.Y.3    Xie, Y.F.4    Ye, Z.M.5    Xiang, J.6    Li, D.C.7    Yang, J.C.8
  • 4
    • 0016429845 scopus 로고
    • Tumor angiogenesis: A possible control point in tumor growth
    • Folkman, J. Tumor angiogenesis: a possible control point in tumor growth. Ann Intern Med 82, 96-100 (1975).
    • (1975) Ann Intern Med , vol.82 , pp. 96-100
    • Folkman, J.1
  • 5
    • 43249095919 scopus 로고    scopus 로고
    • Tumor angiogenesis
    • Kerbel, R. S. Tumor angiogenesis. New Engl J Med 358, 2039-2049 (2008).
    • (2008) New Engl J Med , vol.358 , pp. 2039-2049
    • Kerbel, R.S.1
  • 6
    • 35348855682 scopus 로고    scopus 로고
    • VEGF: An essential mediator of both angio- genesis and endo- chondral ossification
    • Dai, J., Rabie, A. B. M. VEGF: an essential mediator of both angio- genesis and endo- chondral ossification. J Dent Res 86, 937-950 (2007).
    • (2007) J Dent Res , vol.86 , pp. 937-950
    • Dai, J.1    Rabie, A.B.M.2
  • 7
    • 24744466384 scopus 로고    scopus 로고
    • Bevacizumab-current status and future directions
    • Midgley, R., Kerr, D. Bevacizumab-current status and future directions. Ann Oncol 16, 999-1004 (2005).
    • (2005) Ann Oncol , vol.16 , pp. 999-1004
    • Midgley, R.1    Kerr, D.2
  • 8
    • 72949121716 scopus 로고    scopus 로고
    • Regulation of endometrial vascular remodelling: Role of the vascular endothelial growth factor family and the angiopoietin-TIE signalling system
    • Girling, J. E., Rogers, P. A. W. Regulation of endometrial vascular remodelling: role of the vascular endothelial growth factor family and the angiopoietin-TIE signalling system. Reproduction 138, 883-893 (2009).
    • (2009) Reproduction , vol.138 , pp. 883-893
    • Girling, J.E.1    Rogers, P.A.W.2
  • 9
    • 34548798765 scopus 로고    scopus 로고
    • Tie2-Expressing monocytes and tumor angio- genesis: Regulation by hypoxia and angiopoietin-2
    • Lewis, C. E., De Palma, M., Naldini, L. Tie2-Expressing monocytes and tumor angio- genesis: regulation by hypoxia and angiopoietin-2. Cancer Res 67, 8429-8432 (2007).
    • (2007) Cancer Res , vol.67 , pp. 8429-8432
    • Lewis, C.E.1    de Palma, M.2    Naldini, L.3
  • 13
    • 14644399862 scopus 로고    scopus 로고
    • Up-regulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metal- loprotease, and laminin 5 correlates with the invasiveness of human glioma
    • Guo, P., Imanishi, Y., Cackowski, F. C., Jarzynka, M. J., Tao, H. Q., Nishikawa, R., Hirose, T., Hu, B., Cheng, S. Y. Up-regulation of angiopoietin-2, matrix metalloprotease-2, membrane type 1 metal- loprotease, and laminin 5 correlates with the invasiveness of human glioma. Am J Pathol 166, 877-890 (2005).
    • (2005) Am J Pathol , vol.166 , pp. 877-890
    • Guo, P.1    Imanishi, Y.2    Cackowski, F.C.3    Jarzynka, M.J.4    Tao, H.Q.5    Nishikawa, R.6    Hirose, T.7    Hu, B.8    Cheng, S.Y.9
  • 14
    • 77950843538 scopus 로고    scopus 로고
    • The dicey role of dicer: Implications for RNAi therapy
    • Merritt, W. M., Bar-Eli, M., Sood, A. K. The dicey role of dicer: implications for RNAi therapy. Cancer Res 70, 2571-2574 (2010).
    • (2010) Cancer Res , vol.70 , pp. 2571-2574
    • Merritt, W.M.1    Bar-Eli, M.2    Sood, A.K.3
  • 16
    • 66049141243 scopus 로고    scopus 로고
    • Effect of siRNA targeting HIF-1 alpha combined L-ascorbate on biological behavior of hypoxic MiaPaCa2 Cells
    • Chen, C. G., Tang, P., Yue, J., Ren, P., Liu, X. M., Zhao, X. J., Yu, Z.T. Effect of siRNA targeting HIF-1 alpha combined L-ascorbate on biological behavior of hypoxic MiaPaCa2 Cells. Technol Cancer Res Treat 8, 235-240 (2009).
    • (2009) Technol Cancer Res Treat , vol.8 , pp. 235-240
    • Chen, C.G.1    Tang, P.2    Yue, J.3    Ren, P.4    Liu, X.M.5    Zhao, X.J.6    Yu, Z.T.7
  • 17
    • 74049091776 scopus 로고    scopus 로고
    • Expression of p-Akt and COX-2 in gastric adenocarcinomas and adenovirus mediated Akt1 and COX-2 ShRNA suppresses SGC-7901 gastric adenocarcinoma and U251 glioma cell growth in vitro and in vivo
    • Zhang, J., Zhang, Q. Y., Fu, Y. C., Wang, T., Zhang, J., Xu, P., Zhou, X., Pu, P. Y., Kang, C. S. Expression of p-Akt and COX-2 in gastric adenocarcinomas and adenovirus mediated Akt1 and COX-2 ShRNA suppresses SGC-7901 gastric adenocarcinoma and U251 glioma cell growth in vitro and in vivo. Technol Cancer Res Treat 8, 467-478 (2009).
    • (2009) Technol Cancer Res Treat , vol.8 , pp. 467-478
    • Zhang, J.1    Zhang, Q.Y.2    Fu, Y.C.3    Wang, T.4    Zhang, J.5    Xu, P.6    Zhou, X.7    Pu, P.Y.8    Kang, C.S.9
  • 18
    • 0343851161 scopus 로고    scopus 로고
    • Development of lentiviral vectors for gene therapy for human diseases
    • Buchschacher, G. L., Wong-Staal, F. Development of lentiviral vectors for gene therapy for human diseases. Blood 95, 2499-2504 (2000).
    • (2000) Blood , vol.95 , pp. 2499-2504
    • Buchschacher, G.L.1    Wong-Staal, F.2
  • 19
    • 70449337791 scopus 로고    scopus 로고
    • A Comeback for Gene Therapy
    • Naldini, L. A Comeback for Gene Therapy. Science 326, 805-806 (2009).
    • (2009) Science , vol.326 , pp. 805-806
    • Naldini, L.1
  • 20
    • 0028362876 scopus 로고
    • Requirement of Vascular Integrin Alpha V Beta 3 For Angiogenesis
    • Brooks, P. C., Clark, R. A., Cheresh, D. A. Requirement of vascular integrin alpha v beta 3 for angiogenesis.Science 264, 569-571 (1994).
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 21
    • 4644350822 scopus 로고    scopus 로고
    • Recent developments in diagnosis of pancreatic cancer
    • Takhar, A. S., Palaniappan, P., Dhingsa, R., Lobo, D. N. Recent developments in diagnosis of pancreatic cancer. Brit Med J 329, 668-673 (2004).
    • (2004) Brit Med J , vol.329 , pp. 668-673
    • Takhar, A.S.1    Palaniappan, P.2    Dhingsa, R.3    Lobo, D.N.4
  • 22
    • 33646550512 scopus 로고    scopus 로고
    • Molecular biomarkers: Their increasing role in the diagnosis, characterization, and therapy guidance in pancreatic cancer
    • Jimeno, A., Hidalgo, M. Molecular biomarkers: their increasing role in the diagnosis, characterization, and therapy guidance in pancreatic cancer. Mol Cancer Ther 5, 787-796 (2006).
    • (2006) Mol Cancer Ther , vol.5 , pp. 787-796
    • Jimeno, A.1    Hidalgo, M.2
  • 23
  • 24
    • 0035134082 scopus 로고    scopus 로고
    • Angiopoietin-2 is implicated in the regulation of tumor angiogenesis
    • Yu, Q., Stamenkovic, I. Angiopoietin-2 is implicated in the regulation of tumor angiogenesis. Am J Pathol 158, 563-570 (2001).
    • (2001) Am J Pathol , vol.158 , pp. 563-570
    • Yu, Q.1    Stamenkovic, I.2
  • 26
    • 0030851764 scopus 로고    scopus 로고
    • Signaling vascular morphogenesis and maintenance
    • Hanahan, D. Signaling vascular morphogenesis and maintenance. Science 277, 48 (1997).
    • (1997) Science , vol.277 , pp. 48
    • Hanahan, D.1
  • 27
    • 0035266253 scopus 로고    scopus 로고
    • Angiopoietin-2 is related to tumor angiogenesis in gastric carcinoma: Possible in vivo regulation via induction of proteases
    • Etoh, T., Inoue, H., Tanaka, S., Barnard, G. F., Kitano, S., Mori, M. Angiopoietin-2 is related to tumor angiogenesis in gastric carcinoma: possible in vivo regulation via induction of proteases. Cancer Res 61, 2145-2153 (2001).
    • (2001) Cancer Res , vol.61 , pp. 2145-2153
    • Etoh, T.1    Inoue, H.2    Tanaka, S.3    Barnard, G.F.4    Kitano, S.5    Mori, M.6
  • 28
    • 0038745370 scopus 로고    scopus 로고
    • Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer
    • 34033412
    • Zhang, L., Yang, N., Park, J. W., Katsaros, D., Fracchioli, S., Cao, G. Y., O'Brien-Jenkins, A., Randall, T. C., Rubin, S. C., Coukos, G. Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer. Cancer Res 63, 34033412 (2003).
    • (2003) Cancer Res , pp. 63
    • Zhang, L.1    Yang, N.2    Park, J.W.3    Katsaros, D.4    Fracchioli, S.5    Cao, G.Y.6    O'Brien-Jenkins, A.7    Randall, T.C.8    Rubin, S.C.9    Coukos, G.10
  • 29
    • 0030028585 scopus 로고    scopus 로고
    • CD34: Structure, biology, and clinical utility
    • Krause, D. S., Fackler, M. J., Civin, C. I., May, W. S. CD34: structure, biology, and clinical utility. Blood 87, 1-13 (1996).
    • (1996) Blood , vol.87 , pp. 1-13
    • Krause, D.S.1    Fackler, M.J.2    Civin, C.I.3    May, W.S.4
  • 30
    • 59549100452 scopus 로고    scopus 로고
    • Novel functions of the CD34 family
    • Nielsen, J. S., McNagny, K. M. Novel functions of the CD34 family. J Cell Sci 121, 3683-3692 (2008).
    • (2008) J Cell Sci , vol.121 , pp. 3683-3692
    • Nielsen, J.S.1    McNagny, K.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.