Genomic alterations and phenotype of large compared to small high-grade ductal carcinoma in situ

Human Pathology

Volumn 42, Issue 10, 2011, Pages 1467-1475

  Hwang, E Shelley ^a   Lal, Aseem ^a   Chen, Yunn Yi ^a   Devries, Sandy ^a   Swain, Rebecca ^a   Anderson, Joe ^a   Roy, Ritu ^b   Waldman, Frederic M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Biomarkers; Comparative genomic hybridization; Ductal carcinoma in situ; Immunohistochemistry

Indexed keywords

CD68 ANTIGEN; CYCLIN D1; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; KI 67 ANTIGEN; PROGESTERONE RECEPTOR; PROTEIN P16; PROTEIN P53;

ADULT; AGE; AGED; ANTIGEN EXPRESSION; ARTICLE; CHROMOSOME 20Q; CHROMOSOME 8Q; COMPARATIVE GENOMIC HYBRIDIZATION; FEMALE; GENE AMPLIFICATION; GENE DOSAGE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTRADUCTAL CARCINOMA; LARGE HIGH GRADE INTRADUCTAL CARCINOMA; MACROPHAGE; MAJOR CLINICAL STUDY; MICROARRAY ANALYSIS; PHENOTYPE; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; SMALL HIGH GRADE INTRADUCTAL CARCINOMA; TUMOR NECROSIS;

ADULT; AGE FACTORS; AGED; BREAST NEOPLASMS; CARCINOMA IN SITU; CARCINOMA, DUCTAL, BREAST; COMPARATIVE GENOMIC HYBRIDIZATION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 80053216883     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2011.01.002     Document Type: Article

References (39)

1. M.J. Silverstein, M.D. Lagios, and P.H. Craig A prognostic index for ductal carcinoma in situ of the breast Cancer 77 1996 2267 2274 (Pubitemid 26162419)
2. G. MacGrogan, F. Bonichon, and I. de Mascarel Prognostic value of p53 in breast invasive ductal carcinoma: an immunohistochemical study on 942 cases Breast Cancer Res Treat 36 1995 71 81
3. M.L. Gauthier, H.K. Berman, and C. Miller Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors Cancer Cell 12 2007 479 491 (Pubitemid 350046408)
4. A.C. Wolff, M.E. Hammond, and J.N. Schwartz American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer J Clin Oncol 25 2007 118 145 (Pubitemid 350003059)
5. S. Devries, S. Nyante, and J. Korkola Array-based comparative genomic hybridization from formalin-fixed, paraffin-embedded breast tumors J Mol Diagn 7 2005 65 71 (Pubitemid 40310167)
6. A.M. Snijders, N. Nowak, and R. Segraves Assembly of microarrays for genome-wide measurement of DNA copy number Nat Genet 29 2001 263 264 (Pubitemid 33096449)
7. E.S. Hwang, S.J. Nyante, and Y. Yi Chen Clonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma Cancer 100 2004 2562 2572 (Pubitemid 38715760)
8. H. Willenbrock, and J. Fridlyand A comparison study: applying segmentation to array CGH data for downstream analyses Bioinformatics 21 2005 4084 4091 (Pubitemid 41672097)
9. G.K. Smyth Linear models and empirical bayes methods for assessing differential expression in microarray experiments Stat Appl Genet Mol Biol 3 2004 Article3
10. H. Fujii, R. Szumel, and C. Marsh Genetic progression, histological grade, and allelic loss in ductal carcinoma in situ of the breast Cancer Res 56 1996 5260 5265 (Pubitemid 26383045)
11. E.S. Hwang, S. DeVries, and K.L. Chew Patterns of chromosomal alterations in breast ductal carcinoma in situ Clin Cancer Res 10 2004 5160 5167 (Pubitemid 39099791)
12. H. Buerger, F. Otterbach, and R. Simon Comparative genomic hybridization of ductal carcinoma in situ of the breast-evidence of multiple genetic pathways J Pathol 187 1999 396 402 (Pubitemid 29118269)
13. A.J. Karayiannakis, E.A. Bastounis, and E.B. Chatzigianni Immunohistochemical detection of oestrogen receptors in ductal carcinoma in situ of the breast Eur J Surg Oncol 22 1996 578 582 (Pubitemid 27036196)
14. J.F. Robertson, K. Bates, and D. Pearson Comparison of two oestrogen receptor assays in the prediction of the clinical course of patients with advanced breast cancer Br J Cancer 65 1992 727 730
15. H.J. Helin, M.J. Helle, and O.P. Kallioniemi Immunohistochemical determination of estrogen and progesterone receptors in human breast carcinoma. Correlation with histopathology and DNA flow cytometry Cancer 63 1989 1761 1767 (Pubitemid 19110615)
16. A. Reiner, G. Reiner, and J. Spona Histopathologic characterization of human breast cancer in correlation with estrogen receptor status. A comparison of immunocytochemical and biochemical analysis Cancer 61 1988 1149 1154 (Pubitemid 18078604)
17. L.C. Collins, and S.J. Schnitt HER2 protein overexpression in estrogen receptor-positive ductal carcinoma in situ of the breast: frequency and implications for tamoxifen therapy Mod Pathol 18 2005 615 620 (Pubitemid 40676371)
18. R.B. Hird, A. Chang, and V. Cimmino Impact of estrogen receptor expression and other clinicopathologic features on tamoxifen use in ductal carcinoma in situ Cancer 106 2006 2113 2118 (Pubitemid 43673231)
19. P. Meijnen, J.L. Peterse, and N. Antonini Immunohistochemical categorisation of ductal carcinoma in situ of the breast Br J Cancer 98 2008 137 142
20. P. Tang, X. Wang, and L. Schiffhauer Expression patterns of ER-alpha, PR, HER-2/neu, and EGFR in different cell origin subtypes of high grade and non-high grade ductal carcinoma in situ Ann Clin Lab Sci 36 2006 137 143
21. B. Zafrani, A. Leroyer, and A. Fourquet Mammographically-detected ductal in situ carcinoma of the breast analyzed with a new classification. A study of 127 cases: correlation with estrogen and progesterone receptors, p53 and c-erbB-2 proteins, and proliferative activity Semin Diagn Pathol 11 1994 208 214 (Pubitemid 24308081)
22. K.M. Alle, S.M. Henshall, and A.S. Field Cyclin D1 protein is overexpressed in hyperplasia and intraductal carcinoma of the breast Clin Cancer Res 4 1998 847 854 (Pubitemid 28183384)
23. D.M. Barnes, and C.E. Gillett Cyclin D1 in breast cancer Breast Cancer Res Treat 52 1998 1 15 (Pubitemid 29056081)
24. C.E. Gillett, A.H. Lee, and R.R. Millis Cyclin D1 and associated proteins in mammary ductal carcinoma in situ and atypical ductal hyperplasia J Pathol 184 1998 396 400
25. K. Kerlikowske, A. Molinaro, and I. Cha Characteristics associated with recurrence among women with ductal carcinoma in situ treated by lumpectomy J Natl Cancer Inst 95 2003 1692 1702 (Pubitemid 37509078)
26. K. Kerlikowske, A.M. Molinaro, and M.L. Gauthier Biomarker expression and risk of subsequent tumors after initial ductal carcinoma in situ diagnosis J Natl Cancer Inst 102 2010 627 637
27. G.Y. Kwon, S.D. Lee, and E.S. Park Mast cell and macrophage counts and microvessel density in invasive breast carcinoma-comparison analysis with clinicopathological parameters Cancer Res Treat 37 2005 103 108
28. E.B. Claus, P. Chu, and C.L. Howe Pathobiologic findings in DCIS of the breast: morphologic features, angiogenesis, HER-2/neu and hormone receptors Exp Mol Pathol 70 2001 303 316 (Pubitemid 32607203)
29. J.D. Brenton, L.A. Carey, and A.A. Ahmed Molecular classification and molecular forecasting of breast cancer: ready for clinical application? J Clin Oncol 23 2005 7350 7360 (Pubitemid 46202348)
30. C.M. Perou, S.S. Jeffrey, and M. van de Rijn Distinctive gene expression patterns in human mammary epithelial cells and breast cancers Proc Natl Acad Sci U S A 96 1999 9212 9217 (Pubitemid 29374734)
31. T. Sorlie, C.M. Perou, and R. Tibshirani Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications Proc Natl Acad Sci U S A 98 2001 10869 10874 (Pubitemid 32878711)
32. T. Sorlie, R. Tibshirani, and J. Parker Repeated observation of breast tumor subtypes in independent gene expression data sets Proc Natl Acad Sci U S A 100 2003 8418 8423 (Pubitemid 36842560)
33. R.M. Tamimi, H.J. Baer, and J. Marotti Comparison of molecular phenotypes of ductal carcinoma in situ and invasive breast cancer Breast Cancer Res 10 2008 R67
34. R.E. Ellsworth, D.L. Ellsworth, and B. Love Correlation of levels and patterns of genomic instability with histological grading of DCIS Ann Surg Oncol 14 2007 3070 3077 (Pubitemid 47594271)
35. J.S. Reis-Filho, P.T. Simpson, and T. Gale The molecular genetics of breast cancer: the contribution of comparative genomic hybridization Pathol Res Pract 201 2005 713 725 (Pubitemid 41671175)
36. R. Roylance, P. Gorman, and W. Harris Comparative genomic hybridization of breast tumors stratified by histological grade reveals new insights into the biological progression of breast cancer Cancer Res 59 1999 1433 1436 (Pubitemid 29160105)
37. P.T. Simpson, J.S. Reis-Filho, and T. Gale Molecular evolution of breast cancer J Pathol 205 2005 248 254
38. C.B. Vos, N.T. ter Haar, and C. Rosenberg Genetic alterations on chromosome 16 and 17 are important features of ductal carcinoma in situ of the breast and are associated with histologic type Br J Cancer 81 1999 1410 1418
39. T. Kuukasjarvi, M. Tanner, and S. Pennanen Genetic changes in intraductal breast cancer detected by comparative genomic hybridization Am J Pathol 150 1997 1465 1471 (Pubitemid 27152663)