Pro-sexual effects of aqueous extracts of Massularia acuminata root in male Wistar rats

Andrologia

Volumn 43, Issue 5, 2011, Pages 334-340

  Yakubu, M T ^a   Awotunde, O S ^a   Ajiboye, T O ^a   Oladiji, A T ^a   Akanji, M A ^a  

^a UNIVERSITY OF ILORIN   (Nigeria)

Author keywords

Male sexual dysfunction; Massularia acuminata; Prosexual activity; Rubiacea; Testosterone

Indexed keywords

ALKALOID; ANTHRAQUINONE DERIVATIVE; FLAVONOID; FOLLITROPIN; LUTEINIZING HORMONE; MASSULARIA ACUMINATA EXTRACT; PHENOL DERIVATIVE; PLANT EXTRACT; SAPONIN; SILDENAFIL; TANNIN DERIVATIVE; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EJACULATION; ERECTILE DYSFUNCTION; FEMALE; HYPOACTIVE SEXUAL DESIRE DISORDER; MALE; MASSULARIA ACUMINATA; NONHUMAN; PHYTOCHEMISTRY; PLANT ROOT; PREMATURE EJACULATION; RAT; RUBIACEAE; SEXUAL BEHAVIOR; TESTOSTERONE BLOOD LEVEL;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MALE; PLANT EXTRACTS; PLANT ROOTS; RATS; RATS, WISTAR; SEXUAL BEHAVIOR, ANIMAL;

EID: 80053209810     PISSN: 03034569     EISSN: 14390272     Source Type: Journal    
DOI: 10.1111/j.1439-0272.2011.01080.x     Document Type: Article

References (34)

1. Adimoelja A (2000) Phytochemicals and the breakthrough of traditional herbs in the management of sexual dysfunction. Int J Androl 23(Suppl 2):82-84.
2. Ageel AM, Islam MW, Ginawi OT, Al-yahya MA (1994) Evaluation of the aphrodisiac activities of Litsea chinensis (Lauraceae) and Orchis maculata (Orchidaceae) extracts in rats. Phytother Res 8:103-105.
3. Agmo A (1997) Male rat sexual behaviour. Brain Res Protocol 1:203-209.
4. Amin KMY, Khan MN, Rahman SZ, Khan NA (1996) Sexual function improving effect of Mucuna pruriens in sexually normal male rats. Fitoterapia 67:53-58.
5. Anderson KE (2001) Pharmacology of penile erection. Pharmacol Rev 53:417-450.
6. Ayta IA, McKinlay JB, Krane RJ (1999) The likely world increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. Br J Urol Int 84:50-56.
7. Cicero AFG, Bandieri E, Arletti R (2001) Lepidium meyenii Walp. Improves sexual behaviour in male rats independently from its action on spontaneous locomotor activity. J Ethnopharmacol 75:225-229.
8. Drewes SE, George J, Khan F (2003) Recent findings on natural products with erectile-dysfunction activity. Phytochem 62:1019-1025.
9. El-Olemy MM, Al-Muhtadi FJ, Afifi AA (1994) Experimental Phytochemistry. A Laboratory Manual. King Saud University Press Riyadh, Saudi Arabia, 3-137.
10. Farnsworth NR, Akerele O, Bingel AS, Soejarto DD, Guo ZG (1985) Medicinal plants in therapy. Bull WHO 63:965-981.
11. Gauthaman K, Ganesan AP (2008) The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction - an evaluation using primates, rabbit and rat. Phytomedicine 15:44-54.
12. Gill LS (1992) Ethnomedical Uses of Plants in Nigeria. Uniben Press, Benin, Nigeria, 143.
13. Guay AT, Spark RF, Bansal S, Cunningham GR, Goodman NF, Nankin HR, Petak SM, Perez JB (2003) American Association of Clinical Endocrinologists: medical guidelines for clinical practice for the evaluation and treatment of male sexual dysfunction. A couple's problem. Endocrinol Pract 9:78-95.
14. Harborne JB (1984) Significance of Difference in Means. In: A Guide to Modern Techniques of Plant Analysis. Harborne JB (eds.). Chapman and Hall, London, p 192.
15. Hollister LE (1975) The mystique of social drugs and sex. In: Sexual Behavior: Pharmacology and Biochemistry. Sandler M, Gessa GL (eds). Raven Press, New York, NY, pp 85-92.
16. Kirkorian A (1984) Khat and its use: a historical perspective. J Ethnopharmacol 12:115-178.
17. Mahajan BK (1997) In: Methods in Biostatistics for Medical and Research Workers. Mahajan BK (ed). JAYPEE Brothers Medical Publishers, New Delhi, pp 130-155.
18. Mallis D, Mosidis K, Kirana PS, Papaharitou S, Simos G, Hatzichristou D (2006) Moderate and severe erectile dysfunction equally affects life satisfaction. J Sex Med 3:442-449.
19. Mbongue FGY, Kamtchouing P, Essame OJL, Yewah PM, Dimo T, Lontsi D (2005) Effect of the aqueous extract of dry fruits of Piper guineense on the reproductive function of adult male rats. Indian J Pharmacol 37:30-32.
20. Moffat SD, Hampson E (1996) A curvilinear relationship between testosterone and spatial cognition in humans: possible influence of hand preference. Psychoneuroendocrinology 21:323-337.
21. Obadoni BO, Ochuko PO (2001) Phytochemical studies and comparative efficacy of the crude extracts of some homeostatic plants in Edo and Delta States of Nigeria. Global J Pure Appl Sci 8:203-208.
22. Padashetty SA, Mishra SH (2007) Aphrodisiac studies of Tricholepis glaberrima with supportive action from antioxidant enzymes. Pharm Biol 45:580-586.
23. Ratnasooriya WD, Dharmansiri MG (2000) Effects of Terminalia catappa seeds on sexual behaviour and fertility of male rats. Asian J Androl 2:213-219.
24. Slob AK, Van der Werff ten Bosch JJ (1997) The fundamental role of gonadal steroids in sexual behavior. Baillière's Clin Psychol 3:1-24.
25. Sofowora A (1993) Medicinal Plants and Traditional Medicine in Africa. Spectrum Books Limited, Ibadan, Nigeria, 134-156.
26. Tietz NW (1995) Clinical Guide to Laboratory Tests. W. B. Saunders Company, Philadelphia, PA, pp 562-563.
27. Uotila M, Ruoslathi E, Envall E (1981) Two-site sandwich enzyme immunoassay with monoclonal antibodies to human alphafetoprotein. J Immunol Meth 42:11-15.
28. Van-Burden TP, Robinson WC (1981) Formation of complexes between protein and tannic acid. J Agric Food Chem 1:77-79.
29. Watcho P, Zelefack F, Nguelefack BT, Ngouela S, Telefo PB, Kamtchouing P, Tsamo E, Kamanyi A (2007) Effects of the aqueous and hexane extracts of Mondia whitei on the sexual behaviour and some fertility parameters of sexually inexperienced male rats. Afr J Tradit Complement Altern Med 4:27-46.
30. Yakubu MT, Afolayan AJ (2009) Effect of aqueous extract of Bulbine natalensis (Baker) stem on the sexual behaviour of male rats. Int J Androl 32:629-636.
31. Yakubu MT, Akanji MA, Oladiji AT (2007) Male sexual dysfunction and methods used in assessing medicinal plants with aphrodisiac potentials. Pharmacol Rev 1:39-46.
32. Yakubu MT, Akanji MA, Oladiji AT, Adesokan AA (2008) Androgenic potentials of aqueous extract of Massularia acuminata (G. Don) Bullock ex Hoyl. stem in male Wistar rats. J Ethnopharmacol 118:508-513.
33. Zamble A, Sahpaz S, Brunet C, Bailleul F (2008) Effects of Microdesmis keayana roots on sexual behavior of male rats. Phytomedicine 15:625-629.
34. Zanoli P, Benelli A, Rivasi M, Baraldi C, Vezzalini F, Baraldi M (2003) Opposite effect of acute and subchronic treatments with Ferula hermonis on copulatory behavior of male rats. Int J Impot Res 15:450-455.