A model-based theory on the signal transformation for microsaccade generation

Neural Networks

Volumn 24, Issue 9, 2011, Pages 990-997

  Inagaki, Keiichiro ^a   Hirata, Yutaka ^c   Usui, Shiro ^a,b  

^a RIKEN   (Japan)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^c CHUBU UNIVERSITY   (Japan)

Author keywords

Burst neuron; Microsaccade; Modeling study; Omnipause neuron; Saccadic pathway

Indexed keywords

GENERATION MECHANISM; HIGH SPATIAL FREQUENCY; MICROSACCADES; MODELING STUDY; NEURONAL CIRCUITRIES; NEURONAL NETWORKS; PARTIAL RELEASE; PEAK VELOCITIES; SACCADIC PATHWAY; SIGNAL TRANSFORMATION; SQUARE-WAVE; SUPERIOR COLLICULUS;

NEURAL NETWORKS;

EYE MOVEMENTS;

ARTICLE; ARTIFICIAL NEURAL NETWORK; BURST NEURON; EYE FIXATION; EYE MOVEMENT; EYE PLANT; EYE POSITION; INTEGRATOR NEURON; MICROSACCADE; MODEL BASED THEORY; MOTONEURON; NERVOUS SYSTEM PARAMETERS; NEURONAL FIRING RATE; OMNIPAUSE NEURON; PRIORITY JOURNAL; SACCADIC EYE MOVEMENT; SIGNAL PROCESSING; SUPERIOR COLLICULUS; THEORY; TONIC NEURON; VISUAL ADAPTATION;

ALGORITHMS; COMPUTER SIMULATION; ELECTROPHYSIOLOGICAL PHENOMENA; FIXATION, OCULAR; MODELS, NEUROLOGICAL; NEURONS; SACCADES; SIGNAL TRANSDUCTION; SUPERIOR COLLICULI; VISUAL PERCEPTION;

EID: 80053209806     PISSN: 08936080     EISSN: 18792782     Source Type: Journal    
DOI: 10.1016/j.neunet.2011.06.007     Document Type: Article

References (63)

1. Aksay E., Olasagasti I., Mensh B.D., Baker R., Goldman M.S., Tank D.W. Functional dissection of circuitry in a neural integrator. Nature Neuroscience 2007, 10(4):494-504.
2. Barlow H.B. Eye movements during fixation. Journal of Neurophysiology 1952, 116(3):290-306.
3. Bassett J., Ishihara M., Baker R., Hirata Y. Position-specific training in the oculomotor neural integrator. Society for Neuroscience Abstracts 2009, 356.1.
4. Bosman C.A., Womelsdorf T., Desimone R., Fries P. A microsaccadic rhythm modulates gamma-band synchronization and behavior. Journal of Neuroscience 2009, 29(30):9471-9480.
5. Brien D.C., Corneil B.D., Fecteau J.H., Bell A.H., Munoz D.P. The behavioural and neurophysiological modulation of microsaccades in monkeys. Journal of Eye Movement Research 2009, 3(2):1-12. 4.
6. Carpenter R.H.S. Movement of the eye 1977, Pion Press, London.
7. Chimoto S., Iwamoto Y., Shimazu H., Yoshida K. Functional connectivity of the superior colliculus with saccade-related brain stem neurons in the cat. Progress in Brain Research 1996, 112:157-165.
8. Cornsweet T.N. Determination of the stimuli for involuntary drifts and saccadic eye movements. Journal of the Optical Society of America 1956, 46(11):987-993.
9. Cui J., Wilke M., Logothetis N.K., Leopold D.A., Liang H. Visibility states modulate microsaccade rate and direction. Vision Research 2009, 49(2):228-236.
10. Deubel H., Schneider W.X. Saccade target selection and object recognition: evidence for a common attentional mechanism. Vision Research 1996, 36:1827-1837.
11. Ditchburn R.W., Ginsborg B.L. Vision with a stabilized retinal image. Nature 1952, 170(4314):36-37.
12. Ditchburn R.W., Ginsborg B.L. Involuntary eye movements during fixation. Journal of Neurophysiology 1953, 119(1):1-17.
13. Donner K., Hemila S. Modelling the effect of microsaccades on retinal responses to stationary contrast patterns. Vision Research 2007, 47(9):1166-1177.
14. Engbert R. Microsaccades: a microcosm for research on oculomotor control, attention, and visual perception. Progress in Brain Research 2006, 154:177-192.
15. Engbert R., Kliegl R. Microsaccades uncover the orientation of covert attention. Vision Research 2003, 43:1035-1045.
16. Engbert R., Mergenthaler K. Microsaccades are triggered by low retinal image slip. Proceedings of the National Academy of Sciences USA 2006, 103(18):7192-7197.
17. Gandhi N.J., Keller E.L. Activity of the brain stem omnipause neurons during saccades perturbed by stimulation of the primate superior colliculus. Journal of Neurophysiology 1999, 82(6):3254-3267.
18. Guitton D., Munoz D.P. Control of orienting gaze shifts by the tectoreticulospinal system in the head-free cat. I. Identification, localization, and effects of behavior on sensory responses. Journal of Neurophysiology 1991, 66(5):1605-1623.
19. Hafed Z.M., Clark J.J. Microsaccades as an overt measure of covert attention shifts. Vision Research 2002, 42(22):2533-2545.
20. Hafed Z.M., Goffart L., Krauzlis R.J. A neural mechanism for microsaccade generation in the primate superior colliculus. Science 2009, 323(5916):940-943.
21. Herishanu Y.O., Sharpe J.A. Normal square wave jerks. Investigative Ophthalmology & Visual Science 1981, 20(2):268-272.
22. Inagaki K., Kannon T., Kamiyama Y., Satoh S., Kamiji N., Hirata Y., et al. Environment for an integrative model simulation: PLATO. Frontiers in Neuroscience, abstract: Neuroinformatics 2010, 2010:P91.
23. Keller E.L. Participation of medial pontine reticular formation in eye movement generation in monkey. Journal of Neurophysiology 1974, 37(2):316-332.
24. Ko H.K., Poletti M., Rucci M. Microsaccades precisely relocate gaze in a high visual acuity task. Nature Neuroscience 2010, 13:1549-1553.
25. Kowler E., Steinman R.M. Small saccades serve no useful purpose: reply to a letter by R.W. Ditchburn. Vision Research 1980, 20(3):273-276.
26. Krauskopf J., Cornsweet T.N., Riggs L.A. Analysis of eye movements during monocular and binocular fixation. Journal of the Optical Society of America 1960, 50:572-578.
27. Laubrock J., Engbert R., Kliegl R. Microsaccade dynamics during covert attention. Vision Research 2005, 45:721-730.
28. Lopez-Barneo J., Darlot C., Berthoz A., Baker R. Neuronal activity in prepositus nucleus correlated with eye movement in the alert cat. Journal of Neurophysiology 1982, 47(2):329-352.
29. Major G., Baker R., Aksay E., Mensh B., Seung H.S., Tank D.W. Plasticity and tuning by visual feedback of the stability of a neural integrator. Proceedings of the National Academy of Sciences USA 2004, 101(20):7739-7744.
30. Major G., Baker R., Aksay E., Seung H.S., Tank D.W. Plasticity and tuning of the time course of analog persistent firing in a neural integrator. Proceedings of the National Academy of Sciences USA 2004, 101(20):7745-7750.
31. Martinez-Conde S., Macknik S.L., Hubel D.H. Microsaccadic eye movements and firing of single cells in the striate cortex of macaque monkeys. Nature Neuroscience 2000, 3(3):251-258.
32. Martinez-Conde S., Macknik S.L., Hubel D.H. The role of fixational eye movements in visual perception. Nature Reviews Neuroscience 2004, 5(3):229-240.
33. Martinez-Conde S., Macknik S.L., Troncoso X.G., Dyar T.A. Microsaccades counteract visual fading during fixation. Neuron 2006, 49(2):297-305.
34. Martinez-Conde S., Macknik S.L., Troncoso X.G., Hubel D.H. Microsaccades: a neurophysiological analysis. Trends in Neurosciences 2009, 32(9):463-475.
35. Matsumoto M., Nishimura T. Mersenne twister: a 623-dimensionally equidistributed uniform pseudo-random number generator. ACM Transactions on Modeling and Computer Simulation 1998, 8(1):3-30.
36. Mergenthaler K., Engbert R. Microsaccades are different from saccades in scene perception. Experimental Brain Research 2010, 203(4):753-757.
37. Moschovakis A.K. The neural integrators of the mammalian saccadic system. Frontiers in Bioscience 1997, 2:552-577.
38. Moschovakis A.K., Scudder C.A., Highstein S.M. The microscopic anatomy and physiology of the mammalian saccadic system. Progress in Neurobiology 1996, 50(2-3):133-254.
39. Munoz D.P. Saccadic eye movements: overview of neural circuitry. Progress in Brain Research 2002, 140:89-96.
40. Munoz D.P., Guitton D. Control of orienting gaze shifts by the tectoreticulospinal system in the head-free cat. II. Sustained discharges during motor preparation and fixation. Journal of Neurophysiology 1991, 66(5):1624-1641.
41. Munoz D.P., Wurtz R.H. Saccade-related activity in monkey superior colliculus. I. Characteristics of burst and buildup cells. Journal of Neurophysiology 1995, 73(6):2313-2333.
42. Munoz D.P., Wurtz R.H. Saccade-related activity in monkey superior colliculus. II. Spread of activity during saccades. Journal of Neurophysiology 1995, 73(6):2334-2348.
43. Optican L.M. A field theory of saccade generation: temporal-to-spatial transform in the superior colliculus. Vision Research 1995, 35(23-24):3313-3320.
44. Otero-Millan J., Serra A., Leigh R.J., Troncoso X.G., Macknik S.L., Martinez-Conde S. Distinctive features of saccadic intrusions and microsaccades in progressive supranuclear palsy. Journal of Neuroscience 2011, 31(12):4379-4387.
45. Otero-Millan J., Troncoso X.G., Macknik S.L., Serrano-Pedraza I., Martinez-Conde S. Saccades and microsaccades during visual fixation, exploration, and search: foundations for a common saccadic generator. Journal of Vision 2008, 8(14):1-18. 21.
46. Paré M., Guitton D. The fixation area of the cat superior colliculus: effects of electrical stimulation and direct connection with brainstem omnipause neurons. Experimental Brain Research 1994, 101(1):109-122.
47. Pastor A.M., De la Cruz R.R., Baker R. Eye position and eye velocity integrators reside in separate brainstem nuclei. Proceedings of the National Academy of Sciences USA 1994, 91(2):807-811.
48. Riggs L.A., Ratliff F., Cornsweet J.C., Cornsweet T.N. The disappearance of steadily fixated visual test objects. Journal of the Optical Society of America 1953, 43(6):495-501.
49. Robinson D.A. Eye movements evoked by collicular stimulation in the alert monkey. Vision Research 1972, 12(11):1795-1808.
50. Robinson D.A. Models of the saccadic eye movement control system. Kybernetik 1973, 14:71-83.
51. Rolfs M., Kliegl R., Engbert R. Toward a model of microsaccade generation: the case of microsaccadic inhibition. Journal of Vision 2008, 8(11):1-23. 5.
52. Rucci M., Iovin R., Poletti M., Santini F. Miniature eye movements enhance fine spatial detail. Nature 2007, 447(7146):851-854.
53. Scudder C.A., Kaneko C.R.S., Fuchs A.F. The brainstem burst generator for saccadic eye movements: a modern synthesis. Experimental Brain Research 2002, 142:439-462.
54. Seung H.S., Lee D.D., Reis B.Y., Tank D.W. Stability of the memory of eye position in a recurrent network of conductance-based model neurons. Neuron 2000, 26(1):259-271.
55. Skavenski A.A., Robinson D.A. Role of abducens motorneurons in the vestibuloocular reflex. Journal of Neurophysiology 1973, 36(4):724-738.
56. Sparks D.L. The brainstem control of saccadic eye movements. Nature Reviews Neuroscience 2002, 3:952-964.
57. Stanford T.R., Freedman E.G., Sparks D.L. Site and parameters of microstimulation: evidence for independent effects on the properties of saccades evoked from the primate superior colliculus. Journal of Neurophysiology 1996, 76(5):3360-3381.
58. Sylvestre P.A., Cullen K.E. Quantitative analysis of abducens neuron discharge dynamics during saccadic and slow eye movements. Journal of Neurophysiology 1999, 82(5):2612-2632.
59. Troncoso X.G., Macknik S.L., Martinez-Conde S. Microsaccades counteract perceptual filling-in. Journal of Vision 2008, 8(14):1-9. 15.
60. Usui S., Inagaki K., Kannon T., Kamiyama Y., Satoh S., Kamiji N.L., et al. A next generation modeling environment PLATO: platform for collaborative brain system modeling. Lecture Notes in Computer Science 2009, 5863:84-90.
61. Van Horn M., Cullen K.E. Dynamic characterization of microsaccades during near versus far viewing: evidence that microsaccades and saccades are generated by the same premotor circuitry. Society for Neuroscience Abstracts 2009, 405.2.
62. Yoshida K., Iwamoto Y., Chimoto S., Shimazu H. Saccade-related inhibitory input to pontine omnipause neurons: an intracellular study in alert cats. Journal of Neurophysiology 1999, 82(3):1198-1208.
63. Zuber B.L., Stark L., Cook G. Microsaccades and the velocity-amplitude relationship for saccadic eye movements. Science 1965, 150(702):1459-1460.