An improved liquid chromatographic method for the analysis of tylosin and its impurities

Journal of Separation Science

Volumn 34, Issue 19, 2011, Pages 2631-2638

  Ashenafi, Dunge ^a   Hoogmartens, Jos ^a   Adams, Erwin ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

LC; Related substances; Tylosin; Validation

Indexed keywords

CHROMATOGRAPHIC METHODS; LC; LIMIT OF QUANTIFICATIONS; MOBILE PHASIS; PHOSPHATE BUFFERS; RELATED SUBSTANCES; REVERSED PHASE; TYLOSIN; UV DETECTION; VALIDATION;

ACETONITRILE; CHROMATOGRAPHIC ANALYSIS; GRADIENT METHODS; LIQUIDS;

LIQUID CHROMATOGRAPHY;

ACETONITRILE; PHOSPHATE BUFFERED SALINE; TYLOSIN; WATER;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG IMPURITY; FLOW RATE; HIGH TEMPERATURE PROCEDURES; LIMIT OF QUANTITATION; PH; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY; SENSITIVITY ANALYSIS; ULTRAVIOLET RADIATION;

ANTI-BACTERIAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CONTAMINATION; SENSITIVITY AND SPECIFICITY; TYLOSIN;

EID: 80053208920     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201100340     Document Type: Article

References (20)

1. Roets, E., Beirinckx, P., Quintens, I., Hoogmartens, J., J. Chromatogr. 1993, 630, 159-166.
2. Kirst, H. A., Wild, G. M., Baltz, R. H., Hamill, R. L., Ott, J. L., Counter, F. T., Ose, E. E., J. Antibiot. 1982, 35, 1675.
3. Paesen, J., Cypers, W., Busson, R., Roets, E., Hoogmartens, J., J. Chromatogr. A 1995, 699, 99-106.
4. Kennedy, J. H., J. Chromatogr. Sci. 1978, 16, 492-495.
5. Kennedy, J. H., J. Chromatogr. 1983, 281, 288-292.
6. Fish, B. J., Carr, G. P., J. Chromatogr. 1986, 353, 39-50.
7. Tylosin monograph, European Pharmacopoeia, 7th Edn, European Directorate for the Quality of Medicines (EDQM), Strasbourg, France 2011, pp. 3165-3166.
8. Paesen, J., Claeys, P., Cypers, W., Roets, E., Hoogmartens, J., J. Chromatogr. A 1995, 699, 93-97.
9. V. I. C. H. GL10, Proceedings of the International Cooperation on Harmonization of Technical Requirements for Registration of Veterinary Medicinal Products, Geneva, 2007, Step 7 Version.
10. Chepkwony, H. K., Dehouck, P., Roets, E., Hoogmartens, J., Chromatographia 2001, 53, 159-165.
11. Chepkwony, H. K., Vermaelen, A., Roets, E., Hoogmartens, J., Chromatographia 2001, 54, 51-56.
12. Dolan, J. W., LC GC EUR. 2000, 13, 220-224.
13. Haghedooren, E., Kõczián, K., Huang, S., Dragovic, S., Noszál, B., Hoogmartens, J., Adams, E., J. Liq. Chrom. Rel. Technol. 2008, 31, 1081-1103.
14. V. I. C. H. GL1, Proceedings of the International Cooperation on Harmonization of Technical Requirements for Registration of Veterinary Medicinal Products, Geneva, 1998, Step 7 Version.
15. V. I. C. H. GL2, Proceedings of the International Cooperation on Harmonization of Technical Requirements for Registration of Veterinary Medicinal Products, Geneva, 1998, Step 7 Version.
16. Vander Heyden, Y., Nijhuis, A., Smeyers-Verbeke, J., Vandeginste, B. G. M., Massart, D. L., J. Pharm. Biomed. Anal. 2001, 24, 723-753.
17. Massart, D. L., Brereton, R. G., Dessy, R. E., Hopke, P. K., Spiegelman, C. H., Wegscheider, W., Chemometrics Tutorials, Elsevier, Amsterdam 1990.
18. Carlson, R., Design and Optimization in Organic Synthesis, Elsevier, Amsterdam 1992.
19. Massart, D. L., Vandeginste, B. M. G., Buydens, L. M. C., De Jong, S., Lewi, P. J., Smeyers-Verbeke, J., Handbook of Chemometrics and Qualimetrics: Part A, Elsevier, Amsterdam 1997.
20. Massart, D. L., Vandeginste, B. M. G., Buydens, L. M. C., De Jong, S., Lewi, P. J., Smeyers-Verbeke, J., Handbook of Chemometrics and Qualimetrics: Part B, Elsevier, Amsterdam 1998.