Enhanced ca 2 transport and muscle relaxation in skeletal muscle from sarcolipin-null mice

American Journal of Physiology - Cell Physiology

Volumn 301, Issue 4, 2011, Pages

  Tupling, A Russell ^a   Bombardier, Eric ^a   Gupta, Subash C ^e   Hussain, Dawar ^b   Vigna, Chris ^a   Bloemberg, Darin ^a   Quadrilatero, Joe ^a   Trivieri, Maria G ^b,c   Babu, Gopal J ^d   Backx, Peter H ^b,c   Periasamy, Muthu ^e   Maclennan, David H ^b   Gramolini, Anthony O ^b,c  

^a UNIVERSITY OF WATERLOO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^e THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

Caspi 2+ pump; Isolated skeletal muscle; Knockout mouse; Muscle contractility

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CALCIUM ION; MYOSIN HEAVY CHAIN; PROTEIN SARCOLIPIN; PROTEOLIPID PROTEIN; REGULATOR PROTEIN; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG; CALCIUM; MUSCLE PROTEIN; PROTEOLIPID; SARCOLIPIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXTENSOR DIGITORUM LONGUS MUSCLE; GASTROCNEMIUS MUSCLE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; ION TRANSPORT; MALE; MOUSE; MUSCLE CONTRACTILITY; MUSCLE RELAXATION; MUSCLE TETANIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SKELETAL MUSCLE; SOLEUS MUSCLE; WESTERN BLOTTING; WILD TYPE; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; HEART MUSCLE; METABOLISM; MOUSE MUTANT; MUSCLE CONTRACTION; MUTATION; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

MUS;

ANIMALS; BIOLOGICAL TRANSPORT; CALCIUM; GENE EXPRESSION REGULATION; MICE; MICE, KNOCKOUT; MUSCLE CONTRACTION; MUSCLE PROTEINS; MUSCLE RELAXATION; MUTATION; MYOCARDIUM; PROTEOLIPIDS; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES;

EID: 80053200007     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00409.2010     Document Type: Article

References (39)

1. 2+-ATPases (SERCAs). J Biol Chem 277: 26725-26728, 2002.
2. 2+ ATPase (SERCA2a) activity and impairs cardiac function in mice. Proc Natl Acad Sci USA 101: 9199-9204, 2004.
3. 2+-ATPase (SERCA) by binding to transmembrane helices alone or in association with phospholamban. Proc Natl Acad Sci USA 100: 5040-5045, 2003.
4. Babu GJ, Bhupathy P, Carnes CA, Billman GE, Periasamy M. Differential expression of sarcolipin protein during muscle development and cardiac pathophysiology. J Mol Cell Cardiol 42: 215-222, 2007.
5. Babu GJ, Bhupathy P, Petrashevskaya NN, Wang H, Raman S, Wheeler D, Jagatheesan G, Wieczorek D, Schwartz A, Janssen PM, Ziolo MT, Periasamy M. Targeted overexpression of sarcolipin in the mouse heart decreases sarcoplasmic reticulum calcium transport and cardiac contractility. J Biol Chem 281: 3972-3979, 2006.
6. Babu GJ, Bhupathy P, Timofeyev V, Petrashevskaya NN, Reiser PJ, Chiamvimonvat N, Periasamy M. Ablation of sarcolipin enhances sarcoplasmic reticulum calcium transport and atrial contractility. Proc Natl Acad Sci USA 104: 17867-17872, 2007.
7. Babu GJ, Zheng Z, Natarajan P, Wheeler D, Janssen PM, Periasamy M. Overexpression of sarcolipin decreases myocyte contractility and calcium transient. Cardiovasc Res 65: 177-186, 2005.
8. Bhupathy P, Babu GJ, Ito M, Periasamy M. Threonine-5 at the N-terminus can modulate sarcolipin function in cardiac myocytes. J Mol Cell Cardiol 47: 723-729, 2009.
9. 2+ ATPase. J Mol Cell Cardiol 42: 903-911, 2007.
10. Campanaro S, Romualdi C, Fanin M, Celegato B, Pacchioni B, Trevisan S, Laveder P, De Pitta C, Pegoraro E, Hayashi YK, Valle G, Angelini C, Lanfranchi G. Gene expression profiling in dysferlinopathies using a dedicated muscle microarray. Hum Mol Genet 11: 3283-3298, 2002.
11. (2+)-calmodulindependent protein kinase. Biochim Biophys Acta 1464: 231-241, 2000.
12. 2+-cycling responses to prolonged cycling, with and without glucose supplementation. J Appl Physiol 103: 1986-1998, 2007.
13. Fu M, Tupling AR. Protective effects of Hsp70 on the structure and function of SERCA2a expressed in HEK-293 cells during heat stress. Am J Physiol Heart Circ Physiol 296: H1175-H1183, 2009.
14. Gramolini AO, Belanger G, Thompson JM, Chakkalakal JV, Jasmin BJ. Increased expression of utrophin in a slow vs. a fast muscle involves posttranscriptional events. Am J Physiol Cell Physiol 281: C1300-C1309, 2001.
15. Gramolini AO, Jasmin BJ. Expression of the utrophin gene during myogenic differentiation. Nucleic Acids Res 27: 3603-3609, 1999.
16. Gramolini AO, Trivieri MG, Oudit GY, Kislinger T, Li W, Patel MM, Emili A, Kranias EG, Backx PH, MacLennan DH. Cardiac-specific overexpression of sarcolipin in phospholamban null mice impairs myocyte function that is restored by phosphorylation. Proc Natl Acad Sci USA 103: 2446-2451, 2006.
17. Koss KL, Ponniah S, Jones WK, Grupp IL, Kranias EG. Differential phospholamban gene expression in murine cardiac compartments. Molecular and physiological analyses. Circ Res 77: 342-353, 1995.
18. Luo W, Grupp IL, Harrer J, Ponniah S, Grupp G, Duffy JJ, Doetschman T, Kranias EG. Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation. Circ Res 75: 401-409, 1994.
19. MacLennan DH, Kranias EG. Phospholamban: a crucial regulator of cardiac contractility. Nat Rev Mol Cell Biol 4: 566-577, 2003.
20. MacLennan DH, Yip CC, Iles GH, Seeman P. Isolation of sarcoplasmic reticulum proteins. Cold Spring Harb Symp Quant Biol 37: 469-478, 1972.
21. McMillan EM, Quadrilatero J. Differential apoptosis-related protein expression, mitochondrial properties, proteolytic enzyme activity, and DNA fragmentation between skeletal muscles. Am J Physiol Regul Integr Comp Physiol 300: R531-R543, 2011.
22. Minamisawa S, Wang Y, Chen J, Ishikawa Y, Chien KR, Matsuoka R. Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling. J Biol Chem 278: 9570-9575, 2003.
23. 2+ storage levels in sarcoplasmic reticulum of fast-and slow-twitch fibres of rat. J Physiol 587: 443-460, 2009.
24. 2+-ATPase. J Biol Chem 273: 12360-12369, 1998.
25. Odermatt A, Taschner PE, Scherer SW, Beatty B, Khanna VK, Cornblath DR, Chaudhry V, Yee WC, Schrank B, Karpati G, Breuning MH, Knoers N, MacLennan DH. Characterization of the gene encoding human sarcolipin (SLN), a proteolipid associated with SERCA1: absence of structural mutations in five patients with Brody disease. Genomics 45: 541-553, 1997.
26. Ottenheijm CAC, Fong C, Vangheluwe P, Wuytack F, Babu GJ, Periasamy M, Witt CC, Labeit S, Granzier H. Sarcoplasmic reticulum calcium uptake and speed of relaxation are depressed in nebulin-free skeletal muscle. FASEB J 22: 2912-2919, 2008.
27. 2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice. J Biol Chem 278: 13367-13375, 2003.
28. 2+-calmodulin-dependent protein kinase expression and signalling in skeletal muscle during exercise. J Physiol 574: 889-903, 2006.
29. Schertzer JD, van der Poel C, Shavlakadze T, Grounds MD, Lynch GS. Muscle-specific overexpression of IGF-I improves E-C coupling in skeletal muscle fibers from dystrophic mdx mice. Am J Physiol Cell Physiol 294: C161-C168, 2008.
30. Simmerman HK, Jones LR. Phospholamban: protein structure, mechanism of action, and role in cardiac function. Physiol Rev 78: 921-947, 1998.
31. Sun YB, Lou F, Edman KA. The relationship between the intracellular Ca2_ transient and the isometric twitch force in frog muscle fibres. Exp Physiol 81: 711-724, 1996.
32. 2+ uptake and impairs contractile function. J Biol Chem 277: 44740-44746, 2002.
33. Vangheluwe P, Schuermans M, Zador E, Waelkens E, Raeymaekers L, Wuytack F. Sarcolipin and phospholamban mRNA and protein expression in cardiac and skeletal muscle of different species. Biochem J 389: 151-159, 2005.
34. Vasu VT, Ott S, Hobson B, Rashidi V, Oommen S, Cross CE, Gohil K. Sarcolipin and ubiquitin carboxy-terminal hydrolase 1 mRNAs are overexpressed in skeletal muscles of -tocopherol deficient mice. Free Radic Res 43: 106-116, 2009.
35. Wawrzynow A, Theibert JL, Murphy C, Jona I, Martonosi A, Collins JH. Sarcolipin, the "proteolipid" of skeletal muscle sarcoplasmic reticulum, is a unique, amphipathic, 31-residue peptide. Arch Biochem Biophys 298: 620-623, 1992.
36. (2+)-ATPase isoforms in rat muscles. Am J Physiol Cell Physiol 264: C333-C341, 1993.
37. Zhai J, Schmidt AG, Hoit BD, Kimura Y, MacLennan DH, Kranias EG. Cardiac-specific overexpression of a superinhibitory pentameric phospholamban mutant enhances inhibition of cardiac function in vivo. J Biol Chem 275: 10538-10544, 2000.
38. 2+-binding proteins. Prog Clin Biol Res 168: 19-23, 1984.
39. Zvaritch E, Backx PH, Jirik F, Kimura Y, de Leon S, Schmidt AG, Hoit BD, Lester JW, Kranias EG, MacLennan DH. The transgenic expression of highly inhibitory monomeric forms of phospholamban in mouse heart impairs cardiac contractility. J Biol Chem 275: 14985-14991, 2000.