Sex differences in dopamine D2-like receptor-mediated G-protein activation in the medial prefrontal cortex after cocaine

Ethnicity and Disease

Volumn 20, Issue 1 SUPPL.1, 2010, Pages

  Sun, Wei Lun ^a,b   Festa, Eugene D ^a,b   Jenab, Shirzad ^a,b   Quinones Jenab, Vanya ^a,b  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Cocaine; Cortex; Dopamine; G protein

Indexed keywords

COCAINE; DOPAMINE D2 LIKE RECEPTOR; DOPAMINE RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; CAUDATE NUCLEUS; COCAINE DEPENDENCE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; FRONTAL CORTEX; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PUTAMEN; RAT; SEX DIFFERENCE;

EID: 80053188815     PISSN: 1049510X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (19)

1. Adams JU, Careri JM, Efferen TR, et al. Differential effects of dopamine antagonists on locomotor activity, conditioned activity and conditioned place preference induced by cocaine in rats. Behav. Pharmacol. 2001;12: 603-611. (Pubitemid 34017106)
2. Becker JB. Gender differences in dopaminergic function in striatum and nucleus accumbens. Pharmacol. Biochem. Behav. 1999;64:803-812.
3. Beyer CE, Steketee JD. Cocaine sensitization: Modulation by dopamine D2 receptors. Cereb. Cortex. 2002;12:526-535. (Pubitemid 34578667)
4. Chausmer AL, Katz JL. The role of D2-like dopamine receptors in the locomotor stimulant effects of cocaine in mice. Psychopharmacology (Berl). 2001;155:69-77. (Pubitemid 32295771)
5. Clopton J, Gordon JH. In vivo effects of estrogen and 2-hydroxyestradiol on D-2 dopamine receptor agonist affinity states in rat striatum. J. Neural Transm. 1986;66: 13-20. (Pubitemid 16011943)
6. Febo M, Gonzalez-Rodriguez LA, Capo- Ramos DE, et al. Estrogen-dependent alterations in D2/D3-induced G protein activation in cocaine-sensitized female rats. J. Neurochem. 2003;86:405-412. (Pubitemid 36842439)
7. Festa ED, Jenab S, Weiner J, et al. Cocaine-induced sex differences in D1 receptor activation and binding levels after acute cocaine administration. Brain Res. Bull. 2006;68: 277-284. (Pubitemid 41827731)
8. Festa ED, Quinones-Jenab V. Gonadal hormones provide the biological basis for sex differences in behavioral responses to cocaine. Horm Behav. 2004;46:509-19. (Pubitemid 39535131)
9. Frantz KJ, van Hartesveldt C. The locomotor effects of quinpirole in rats depend on age and gender. Pharmacol. Biochem. Behav. 1999;64: 821-826.
10. 35S]GTPγS binding in the rat striatum. Brain Res. 2000;885:133-136.
11. Hyman SE, Malenka RC. Addiction and the brain: The neurobiology of compulsion and its persistence. Nat. Rev. Neurosci. 2001;2: 695-703. (Pubitemid 33674815)
12. Lynch WJ, Carroll ME. Reinstatement of cocaine self-administration in rats: Sex differences. Psychopharmacology (Berl). 2000;148: 196-200. (Pubitemid 30104142)
13. Nestler EJ, Terwilliger RZ, Walker JR, et al. Chronic cocaine treatment decreases levels of the G protein subunits Gi alpha and Go alpha in discrete regions of rat brain. J. Neurochem. 1990;55:1079-1082.
14. Russo SJ, Jenab S, Fabian SJ, et al. Sex differences in the conditioned rewarding effects of cocaine. Brain Res. 2003;970:214-220. (Pubitemid 36423197)
15. Schindler CW, Carmona GN. Effects of dopamine agonists and antagonists on locomotor activity in male and female rats. Pharmacol. Biochem. Behav. 2002;72: 857-863. (Pubitemid 34621312)
16. 35S]thio]-triphosphate binding. Proc. Natl Acad. Sci. 1995;92:7242-7246.
17. Striplin CD, Kalivas PW. Robustness of G protein changes in cocaine sensitization shown with immunoblotting, Synapse, 14(1993): 10-15. (Pubitemid 23138173)
18. Szumlinski KK, Goodwill AM, Szechtman H. Locomotor sensitization to quinpirole in rats: Effects of drug abstinence and sex. Psychopharmacology (Berl). 2000;152:304-311.
19. Tzschentke TM. The medial prefrontal cortex as a part of the brain reward system. Amino Acids. 2000;19:211-219.