Molecular characterization and functional expression of the DSC1 channel

Insect Biochemistry and Molecular Biology

Volumn 41, Issue 7, 2011, Pages 451-458

  Zhang, Tianxiang ^a   Liu, Zhiqi ^b   Song, Weizhong ^b   Du, Yuzhe ^b   Dong, Ke ^b  

^a Michigan State University ^*  (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Alternative splicing; Drosophila Sodium Channel 1; RNA editing; Voltage gated ion channel

Indexed keywords

CALCIUM; COMPLEMENTARY DNA; DROSOPHILA PROTEIN; ISOPROTEIN; RECOMBINANT PROTEIN; SODIUM; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CELL MEMBRANE POTENTIAL; CYTOLOGY; DROSOPHILA MELANOGASTER; EXON; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; OOCYTE; PATCH CLAMP; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EDITING; XENOPUS LAEVIS;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CLONING, MOLECULAR; DNA, COMPLEMENTARY; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EXONS; MEMBRANE POTENTIALS; MOLECULAR SEQUENCE DATA; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN ISOFORMS; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA EDITING; SODIUM; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TETRODOTOXIN; TRANSFECTION; XENOPUS LAEVIS;

BLATTELLA GERMANICA; DROSOPHILA MELANOGASTER; INVERTEBRATA; VERTEBRATA;

EID: 80053179911     PISSN: 09651748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ibmb.2011.04.010     Document Type: Article

References (33)

1. Castella C., Amichot M., Bergé J.B., Pauron D. DSC1 channels are expressed in both the central and the peripheral nervous system of adult Drosophila melanogaster. Invert. Neurosci. 2001, 4:85-94.
2. Catterall W.A. From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron 2000, 26:13-25.
3. Dong K. Insect sodium channels and insecticide resistance. Invert. Neurosci. 2007, 7:17-30.
4. Du Y., Nomura Y., Liu Z., Huang Z.Y., Dong K. Functional expression of an arachnid sodium channel reveals residues responsible for tetrodotoxin resistance in invertebrate sodium channels. J. Biol. Chem. 2009, 284:33869-33875.
5. Feng G., Deák P., Chopra M., Hall L.M. Cloning and functional analysis of TipE, a novel membrane protein that enhances Drosophila para sodium channel function. Cell 1995, 82:1001-1011.
6. Germeraad S., O'Dowd D., Aldrich R.W. Functional assay of a putative Drosophila sodium channel gene in homozygous deficiency neurons. J. Neurogenet. 1992, 8:1-16.
7. Goldin A.L. Maintenance of Xenopus laevis and oocyte injection. Methods Enzymol. 1992, 207:266-279.
8. Heinemann S.H., Terlau H., Stühmer W., Imoto K., Numa S. Calcium channel characteristics conferred on the sodium channel by single mutations. Nature 1992, 356:441-443.
9. Hong C.S., Ganetzky B. Spatial and temporal expression patterns of two sodium channel genes in Drosophila. J. Neurosci. 1994, 14:5160-5169.
10. Hoopengardner B., Bhalla T., Staber C., Reenan R.A. Nervous system targets of RNA editing identified by comparative genomics. Science 2003, 301:832-836.
11. Kerr N.C., Holmes F.E., Wynick D. Novel mRNA isoforms of the sodium channels Na(v)1.2, Na(v)1.3 and Na(v)1.7 encode predicted two-domain, truncated proteins. Neuroscience 2008, 155:797-808.
12. Kulkarni N.H., Yamamoto A.H., Robinson K.O., Mackay T.F., Anholt R.R. The DSC1 channel, encoded by the smi60E locus, contributes to odor-guided behavior in Drosophila melanogaster. Genetics 2002, 161:1507-1516.
13. Lin W.H., Wright D.E., Muraro N.I., Baines R.A. Alternative splicing in the voltage-gated sodium channel DmNav regulates activation, inactivation, and persistent current. J. Neurophysiol. 2009, 102:1994-2006.
14. Littleton J.T., Ganetzky B. Ion channels and synaptic organization: analysis of the Drosophila genome. Neuron 2000, 26:35-43.
15. Liu Z., Chung I., Dong K. Alternative splicing of the BSC1 gene generates tissue-specific isoforms in the German cockroach. Insect. Biochem. Mol. Biol. 2001, 31:703-713.
16. Liu Z., Song W., Dong K. Persistent tetrodotoxin-sensitive sodium current resulting from U-to-C RNA editing of an insect sodium channel. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:11862-11867.
17. Loughney K., Kreber R., Ganetzky B. Molecular analysis of the para locus, a sodium channel gene in Drosophila. Cell 1989, 58:1143-1154.
18. O'Dowd D.K., Gee J.R., Smith M.A. Sodium current density correlates with expression of specific alternatively spliced sodium channel mRNAs in single neurons. J. Neurosci. 1995, 15:4005-4012.
19. Olson R., Liu Z., Nomura Y., Zhang T., Song W., Dong K. Molecular and functional characterization of Para sodium channels in Drosophila melanogaster. Insect. Biochem. Mol. Biol. 2008, 38:604-610.
20. Park Y., Taylor M.F., Feyereisen R. Voltage-gated sodium channel genes hscp and hDSC1 of Heliothis virescens F. genomic organization. Insect. Mol. Biol. 1999, 8:161-170.
21. Plummer N.W., McBurney M.W., Meisler M.H. Alternative splicing of the sodium channel SCN8A predicts a truncated two-domain protein in fetal brain and non-neuronal cells. J. Biol. Chem. 1997, 272:24008-24015.
22. Salkoff L., Butler A., Wei A., Scavarda N., Giffen K., Ifune C., Goodman R., Mandel G. Genomic organization and deduced amino acid sequence of a putative sodium channel gene in Drosophila. Science 1987, 237:744-749.
23. Satin J., Kyle J.W., Chen M., Bell P., Cribbs L.L., Fozzard H.A., Rogart R.B. A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties. Science 1992, 256:1202-1205.
24. Sivilotti L., Okuse K., Akopian A.N., Moss S., Wood J.N. A single serine residue confers tetrodotoxin insensitivity on the rat sensory-neuron-specific sodium channel SNS. FEBS Lett. 1997, 409:49-52.
25. Soderlund D. Sodium channels. Pharmacology 2005, vol. 5:1-24. Elsevier BV, Amsterdam. L.I. Gilbert, K. Iatrou, S.S. Gill (Eds.).
26. Song W., Liu Z., Tan J., Nomura Y., Dong K. RNA editing generates tissue-specific sodium channels with distinct gating properties. J. Biol. Chem. 2004, 279:32554-32561.
27. Tan J., Liu Z., Nomura Y., Goldin A.L., Dong K. Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels. J. Neurosci. 2002, 22:5300-5309.
28. Tatebayashi H., Narahashi T. Differential mechanism of action of the pyrethroid tetramethrin on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels. J. Pharmacol. Exp. Ther. 1994, 270:595-603.
29. Thackeray J.R., Ganetzky B. Developmentally regulated alternative splicing generates a complex array of Drosophila para sodium channel isoforms. J. Neurosci. 1994, 14:2569-2578.
30. Thackeray J.R., Ganetzky B. Conserved alternative splicing patterns and splicing signals in the Drosophila sodium channel gene para. Genetics 1995, 141:203-214.
31. Warmke J.W., Reenan R.A., Wang P., Qian S., Arena J.P., Wang J., Wunderler D., Liu K., Kaczorowski G.J., Van der Ploeg L.H., Ganetzky B., Cohen C.J. Functional expression of Drosophila para sodium channels. Modulation by the membrane protein TipE and toxin pharmacology. J. Gen. Physiol. 1997, 110:119-133.
32. Yu F.H., Yarov-Yarovoy V., Gutman G.A., Catterall W.A. Overview of molecular relationships in the voltage-gated ion channel superfamily. Pharmacol. Rev. 2005, 57:387-395.
33. Zhou W., Chung I., Liu Z., Goldin A.L., Dong K. A voltage-gated calcium-selective channel encoded by a sodium channel-like gene. Neuron 2004, 42:101-112.