Synthesis and biological activities of a novel series of 3,6-disubstituted-1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazoles containing gem-dimethylbenzyl moiety

Journal of Heterocyclic Chemistry

Volumn 48, Issue 5, 2011, Pages 998-1005

  Puthiyapurayil, Pushpan ^a,b   Poojary, Boja ^a   Kumar, Sunil ^c   Hunnur, Raveendra ^c  

^a MANGALORE UNIVERSITY   (India)

^b SYNGENE INTERNATIONAL LTD   (India)

^c NET Pharmacy College   (India)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 2 (4 BROMOPHENYL)PROPANEHYDRAZIDE; 2 METHYL 2 (4 CHLOROPHENYL)PROPANEHYDRAZIDE; 2 METHYL 2 PHENYLPROPANEHYDRAZIDE; 3 (2 PHENYLPROPAN 2 YL) 6 (2 THIENY)[1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 3 (2 PHENYLPROPAN 2 YL) 6 (2,3,4 TRIFLUOROPHENYL)[1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 3 (2 PHENYLPROPAN 2 YL) 6 (3,4,5 TRIMETHYLPHENYL)[1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 3 (2 PHENYLPROPAN 2 YL) 6 (4 TRIFLUOROMETHOXYPHENYL)[1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADI AZOLE; 3 (2 PHENYLPROPAN 2 YL) 6 (4 TRIFLUOROMETHYLPHENYL)[1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADI AZOLE; 3 [2 (4 BROMOPHENYL)PROPAN 2 YL] 6 (2,3,4 TRIFLUOROPHENYL)[1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 3 [2 (4 CHLOROPHENYL)PROPAN 2 YL] 6 (2 TRIFLUOROMETHOXYPHENYL1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZOLE; 3 [2 (4 CHLOROPHENYL)PROPAN 2 YL] 6 (2,3,4 TRIFLUOROPHENYL)[1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 3 [2 (4 CHLOROPHENYL)PROPAN 2 YL] 6 (3,4,5 TRIMETHOXYPHENYL)[1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 3 [2 (4 CHLOROPHENYL)PROPAN 2 YL] 6 (4 FLUOROPHENYL)[1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 4 AMINO 5 (2 PHENYLPROPAN 2 YL) 4H 1,2,4 TRIAZOLE 3 THIOL; 4 AMINO 5 [2 (4 BROMOPHENYL)PROPAN 2 YL] 4H 1,2,4 TRIAZOLE 3 THIOL; 4 AMINO 5 [2 (4 CHLOROPHENYL)PROPAN 2 YL] 4H 1,2,4 TRIAZOLE 3 THIOL; 6 (2 FLUORO 4 TRIFLUOROMETHYLPHENYL) 3 [2 (4 CHLOROPHENYL)PROPAN 2 YL] [1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 6 (3,5 BISTRIFLUOROMETHYLPHENYL) 3 [2 (4 CHLOROPHENYL)PROPAN 2YL][1,2,4]TRIAZOLO[3,4 B][1,3,4] THIADIAZOLE; 6 (4 FLUOROPHENYL) 3 (2 PHENYLPROPAN 2 YL) [1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 6 (4 FLUOROPHENYL) 3 [2 (4 BROMOPHENYL)PROPAN 2 YL][1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; ACETIC ACID DERIVATIVE; METHYL 2 METHYL 2 (4 BROMOPHENYL)PROPANOATE; METHYL 2 METHYL 2 (4 CHLOROPHENYL)PROPANOATE; METHYL 2 METHYL 2 PHENYLPROPANOATE; METHYL 4 BROMOPHENYLACETATE; METHYL 4 CHLOROPHENYLACETATE; PHENYLACETIC ACID METHYL ESTER; PROPIONIC ACID DERIVATIVE; THIADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANALGESIC ACTIVITY; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BIOLOGICAL ACTIVITY; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; DRUG SCREENING; ESCHERICHIA COLI; INFRARED SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; SUBSTITUTION REACTION; SYNTHESIS;

EID: 80053178959     PISSN: 0022152X     EISSN: 19435193     Source Type: Journal    
DOI: 10.1002/jhet.674     Document Type: Article

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