Pharmacokinetic and pharmacodynamic modeling of the effect of an sodium-glucose cotransporter inhibitor, phlorizin, on renal glucose transport in rats

Drug Metabolism and Disposition

Volumn 39, Issue 10, 2011, Pages 1801-1807

  Yamaguchi, Koji ^a   Kato, Motohiro ^a   Suzuki, Masayuki ^a   Asanuma, Kimie ^a   Aso, Yoshinori ^a   Ikeda, Sachiya ^a   Ishigai, Masaki ^a  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; PHLORIZIN; SODIUM GLUCOSE COTRANSPORTER 1; SODIUM GLUCOSE COTRANSPORTER 2;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFICACY; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CLEARANCE; KIDNEY TUBULE ABSORPTION; MALE; MODEL; NONHUMAN; PRIORITY JOURNAL; RAT; SIMULATION;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD GLUCOSE; GLUCOSE; KIDNEY; MALE; MODELS, BIOLOGICAL; NONLINEAR DYNAMICS; PHLORHIZIN; RATS; RATS, SPRAGUE-DAWLEY; SODIUM; SODIUM-GLUCOSE TRANSPORTER 1; SODIUM-GLUCOSE TRANSPORTER 2; TRANSPORT VESICLES;

RATTUS;

EID: 80053164443     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.040048     Document Type: Article

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