Single-base pair unwinding and asynchronous RNA release by the hepatitis C virus NS3 helicase

Science

Volumn 333, Issue 6050, 2011, Pages 1746-1749

  Cheng, Wei ^a   Arunajadai, Srikesh G ^b   Moffitt, Jeffrey R ^c   Tinoco Jr , Ignacio ^d   Bustamante, Carlos ^d  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c HARVARD UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DOUBLE STRANDED RNA; HELICASE; NS3 HELICASE; NUCLEOTIDE; RNA; UNCLASSIFIED DRUG;

HEPATITIS; RNA; TRANSLOCATION; VIRUS;

ARTICLE; BASE PAIRING; ENZYME LOCALIZATION; HEPATITIS C VIRUS; NONHUMAN; PRIORITY JOURNAL; VIRUS REPLICATION;

HEPATITIS C VIRUS;

EID: 80053144268     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1206023     Document Type: Article

References (29)

1. T. M. Lohman, E. J. Tomko, C. G. Wu, Nat. Rev. Mol. Cell Biol. 9, 391 (2008).
2. E. Jankowsky, Trends Biochem. Sci. 36, 19 (2011).
3. S. S. Velankar, P. Soultanas, M. S. Dillingham, H. S. Subramanya, D. B. Wigley, Cell 97, 75 (1999).
4. M. Gu, C. M. Rice, Proc. Natl. Acad. Sci. U.S.A. 107, 521 (2010).
5. T. C. Appleby et al., J. Mol. Biol. 405, 1139 (2011).
6. J. Y. Lee, W. Yang, Cell 127, 1349 (2006).
7. E. J. Tomko, C. J. Fischer, A. Niedziela-Majka, T. M. Lohman, Mol. Cell 26, 335 (2007).
8. V. Rajagopal, M. Gurjar, M. K. Levin, S. S. Patel, J. Biol. Chem. 285, 17821 (2010).
9. S. Myong, M. M. Bruno, A. M. Pyle, T. Ha, Science 317, 513 (2007).
10. A. M. Lam, D. N. Frick, J. Virol. 80, 404 (2006).
11. Y. Ma, J. Yates, Y. Liang, S. M. Lemon, M. Yi, J. Virol. 82, 7624 (2008).
12. A. M. Pyle, Annu Rev Biophys 37, 317 (2008).
13. K. D. Raney, S. D. Sharma, I. M. Moustafa, C. E. Cameron, J. Biol. Chem. 285, 22725 (2010).
14. M. R. Singleton, M. S. Dillingham, D. B. Wigley, Annu. Rev. Biochem. 76, 23 (2007).
15. V. Serebrov, A. M. Pyle, Nature 430, 476 (2004).
16. W. Cheng, S. Dumont, I. Tinoco Jr., C. Bustamante, Proc. Natl. Acad. Sci. U.S.A. 104, 13954 (2007).
17. T. A. Jennings et al., J. Biol. Chem. 284, 4806 (2009).
18. V. Serebrov, R. K. Beran, A. M. Pyle, J. Biol. Chem. 284, 2512 (2009).
19. See supporting material on Science Online.
20. S. Dumont et al., Nature 439, 105 (2006).
21. W. Cheng, X. Hou, F. Ye, Opt. Lett. 35, 2988 (2010).
22. J. R. Moffitt, Y. R. Chemla, D. Izhaky, C. Bustamante, Proc. Natl. Acad. Sci. U.S.A. 103, 9006 (2006).
23. D. S. Johnson, L. Bai, B. Y. Smith, S. S. Patel, M. D. Wang, Cell 129, 1299 (2007).
24. I. Donmez, V. Rajagopal, Y. J. Jeong, S. S. Patel, J. Biol. Chem. 282, 21116 (2007).
25. C. Bustamante, J. F. Marko, E. D. Siggia, S. Smith, Science 265, 1599 (1994).
26. S. G. Arunajadai, Math. Biosci. 220, 57 (2009).
27. R. L. Eoff, K. D. Raney, Nat. Struct. Mol. Biol. 13, 242 (2006).
28. M. N. Dessinges, T. Lionnet, X. G. Xi, D. Bensimon, V. Croquette, Proc. Natl. Acad. Sci. U.S.A. 101, 6439 (2004).
29. S. M. Hamdan, J. J. Loparo, M. Takahashi, C. C. Richardson, A. M. Van Oijen, Nature 457, 336 (2009).