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Volumn 5, Issue 5, 2011, Pages 397-401

Methotrexate in ulcerative colitis: A Spanish multicentric study on clinical use and efficacy

Author keywords

Inflammatory bowel disease; Methotrexate; Ulcerative colitis

Indexed keywords

FOLIC ACID; INFLIXIMAB; MERCAPTOPURINE; METHOTREXATE; STEROID;

EID: 80053132333     PISSN: 18739946     EISSN: 18764479     Source Type: Journal    
DOI: 10.1016/j.crohns.2011.03.012     Document Type: Article
Times cited : (26)

References (35)
  • 1
    • 0034903792 scopus 로고    scopus 로고
    • The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study
    • Faubion W.A., Loftus E.V., Harmsen W.S., Zinsmeister A.R., Sandborn W.J. The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study. Gastroenterology 2001, 121(2):255-260.
    • (2001) Gastroenterology , vol.121 , Issue.2 , pp. 255-260
    • Faubion, W.A.1    Loftus, E.V.2    Harmsen, W.S.3    Zinsmeister, A.R.4    Sandborn, W.J.5
  • 2
    • 33745641871 scopus 로고    scopus 로고
    • The efficacy of corticosteroid therapy in inflammatory bowel disease: analysis of a 5-year UK inception cohort
    • Ho G.T., Chiam P., Drummond H., Loane J., Arnott I.D., Satsangi J. The efficacy of corticosteroid therapy in inflammatory bowel disease: analysis of a 5-year UK inception cohort. Aliment Pharmacol Ther 2006, 24(2):319-330.
    • (2006) Aliment Pharmacol Ther , vol.24 , Issue.2 , pp. 319-330
    • Ho, G.T.1    Chiam, P.2    Drummond, H.3    Loane, J.4    Arnott, I.D.5    Satsangi, J.6
  • 3
    • 29244457275 scopus 로고    scopus 로고
    • Randomised controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis
    • Ardizzone S., Maconi G., Russo A., Imbesi V., Colombo E., Bianchi P.G. Randomised controlled trial of azathioprine and 5-aminosalicylic acid for treatment of steroid dependent ulcerative colitis. Gut 2006, 55(1):47-53.
    • (2006) Gut , vol.55 , Issue.1 , pp. 47-53
    • Ardizzone, S.1    Maconi, G.2    Russo, A.3    Imbesi, V.4    Colombo, E.5    Bianchi, P.G.6
  • 4
    • 0029959419 scopus 로고    scopus 로고
    • Azathioprine is useful in maintaining long-term remission induced by intravenous cyclosporine in steroid-refractory severe ulcerative colitis
    • Fernández Bañares F., Bertrán X., Esteve Comas M., Cabré E., Menacho M., Humbert P., et al. Azathioprine is useful in maintaining long-term remission induced by intravenous cyclosporine in steroid-refractory severe ulcerative colitis. Am J Gastroenterol 1996, 91:2498-2499.
    • (1996) Am J Gastroenterol , vol.91 , pp. 2498-2499
    • Fernández Bañares, F.1    Bertrán, X.2    Esteve Comas, M.3    Cabré, E.4    Menacho, M.5    Humbert, P.6
  • 5
    • 0036909110 scopus 로고    scopus 로고
    • Azathioprine without oral cyclosporin in the long-term maintenance of remission induced by intravenous cyclosporin in severe, steroid-refractory ulcerative colitis
    • Doménech E., Garcia-Planella E., Bernal I., Rosinach M., Cabré E., Fluvià L., et al. Azathioprine without oral cyclosporin in the long-term maintenance of remission induced by intravenous cyclosporin in severe, steroid-refractory ulcerative colitis. Aliment Pharmacol Ther 2002, 16:2061-2065.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 2061-2065
    • Doménech, E.1    Garcia-Planella, E.2    Bernal, I.3    Rosinach, M.4    Cabré, E.5    Fluvià, L.6
  • 6
    • 0036278519 scopus 로고    scopus 로고
    • The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review
    • Fraser A.G., Orchard T.R., Jewell D.P. The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review. Gut 2002, 50(4):485-489.
    • (2002) Gut , vol.50 , Issue.4 , pp. 485-489
    • Fraser, A.G.1    Orchard, T.R.2    Jewell, D.P.3
  • 9
    • 70350622433 scopus 로고    scopus 로고
    • Mucosal healing and steroid-sparing associated with infliximab for steroid-dependent ulcerative colitis
    • Barreiro-de Acosta M., Lorenzo A., Mera J., Dominguez-Muñoz J.E. Mucosal healing and steroid-sparing associated with infliximab for steroid-dependent ulcerative colitis. J Crohn's Colitis 2009, 3(4):271-276.
    • (2009) J Crohn's Colitis , vol.3 , Issue.4 , pp. 271-276
    • Barreiro-de Acosta, M.1    Lorenzo, A.2    Mera, J.3    Dominguez-Muñoz, J.E.4
  • 10
    • 62049083383 scopus 로고    scopus 로고
    • Loss of response and requirement of infliximab dose intensification in Crohn's disease: a review
    • Gisbert J.P., Panes J. Loss of response and requirement of infliximab dose intensification in Crohn's disease: a review. Am J Gastroenterol 2009, 104(3):760-767.
    • (2009) Am J Gastroenterol , vol.104 , Issue.3 , pp. 760-767
    • Gisbert, J.P.1    Panes, J.2
  • 12
    • 0038193465 scopus 로고    scopus 로고
    • Diagnosis and management of pouchitis
    • Mahadevan U., Sandborn W.J. Diagnosis and management of pouchitis. Gastroenterology 2003, 124(6):1636-1650.
    • (2003) Gastroenterology , vol.124 , Issue.6 , pp. 1636-1650
    • Mahadevan, U.1    Sandborn, W.J.2
  • 13
    • 0028899859 scopus 로고
    • Methotrexate for the treatment of Crohn's disease. The North American Crohn's Study Group Investigators
    • Feagan B.G., Rochon J., Fedorak R.N., Irvine E.J., Wild G., Sutherland L., et al. Methotrexate for the treatment of Crohn's disease. The North American Crohn's Study Group Investigators. N Engl J Med 1995, 332(5):292-297.
    • (1995) N Engl J Med , vol.332 , Issue.5 , pp. 292-297
    • Feagan, B.G.1    Rochon, J.2    Fedorak, R.N.3    Irvine, E.J.4    Wild, G.5    Sutherland, L.6
  • 14
    • 0034214336 scopus 로고    scopus 로고
    • A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators
    • Feagan B.G., Fedorak R.N., Irvine E.J., Wild G., Sutherland L., Steinhart A.H., et al. A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators. N Engl J Med 2000, 342(22):1627-1632.
    • (2000) N Engl J Med , vol.342 , Issue.22 , pp. 1627-1632
    • Feagan, B.G.1    Fedorak, R.N.2    Irvine, E.J.3    Wild, G.4    Sutherland, L.5    Steinhart, A.H.6
  • 17
    • 0024517127 scopus 로고
    • Methotrexate induces clinical and histologic remission in patients with refractory inflammatory bowel disease
    • Kozarek R.A., Patterson D.J., Gelfand M.D., Botoman V.A., Ball T.J., Wilske K.R. Methotrexate induces clinical and histologic remission in patients with refractory inflammatory bowel disease. Ann Intern Med 1989, 110(5):353-356.
    • (1989) Ann Intern Med , vol.110 , Issue.5 , pp. 353-356
    • Kozarek, R.A.1    Patterson, D.J.2    Gelfand, M.D.3    Botoman, V.A.4    Ball, T.J.5    Wilske, K.R.6
  • 18
    • 9244264980 scopus 로고    scopus 로고
    • Methotrexate in chronic active ulcerative colitis: a double-blind, randomized, Israeli multicenter trial
    • Oren R., Arber N., Odes S., Moshkowitz M., Keter D., Pomeranz I., et al. Methotrexate in chronic active ulcerative colitis: a double-blind, randomized, Israeli multicenter trial. Gastroenterology 1996, 110(5):1416-1421.
    • (1996) Gastroenterology , vol.110 , Issue.5 , pp. 1416-1421
    • Oren, R.1    Arber, N.2    Odes, S.3    Moshkowitz, M.4    Keter, D.5    Pomeranz, I.6
  • 19
    • 0033679444 scopus 로고    scopus 로고
    • 6-mercaptopurine or methotrexate added to prednisone induces and maintains remission in steroid-dependent inflammatory bowel disease
    • Mate-Jimenez J., Hermida C., Cantero-Perona J., Moreno-Otero R. 6-mercaptopurine or methotrexate added to prednisone induces and maintains remission in steroid-dependent inflammatory bowel disease. Eur J Gastroenterol Hepatol 2000, 12(11):1227-1233.
    • (2000) Eur J Gastroenterol Hepatol , vol.12 , Issue.11 , pp. 1227-1233
    • Mate-Jimenez, J.1    Hermida, C.2    Cantero-Perona, J.3    Moreno-Otero, R.4
  • 21
    • 68949209778 scopus 로고    scopus 로고
    • Efficacy of methotrexate in Crohn's disease and ulcerative colitis patients unresponsive or intolerant to azathioprine /mercaptopurine
    • Wahed M., Louis-Auguste J.R., Baxter L.M., Limdi J.K., McCartney S.A., Lindsay J.O., et al. Efficacy of methotrexate in Crohn's disease and ulcerative colitis patients unresponsive or intolerant to azathioprine /mercaptopurine. Aliment Pharmacol Ther 2009, 30(6):614-620.
    • (2009) Aliment Pharmacol Ther , vol.30 , Issue.6 , pp. 614-620
    • Wahed, M.1    Louis-Auguste, J.R.2    Baxter, L.M.3    Limdi, J.K.4    McCartney, S.A.5    Lindsay, J.O.6
  • 22
    • 0036791285 scopus 로고    scopus 로고
    • Azathioprine or methotrexate in the treatment of patients with steroid-dependent or steroid-resistant ulcerative colitis: results of an open-label study on efficacy and tolerability in inducing and maintaining remission
    • Paoluzi O.A., Pica R., Marcheggiano A., Crispino P., Iacopini F., Iannoni C., et al. Azathioprine or methotrexate in the treatment of patients with steroid-dependent or steroid-resistant ulcerative colitis: results of an open-label study on efficacy and tolerability in inducing and maintaining remission. Aliment Pharmacol Ther 2002, 16(10):1751-1759.
    • (2002) Aliment Pharmacol Ther , vol.16 , Issue.10 , pp. 1751-1759
    • Paoluzi, O.A.1    Pica, R.2    Marcheggiano, A.3    Crispino, P.4    Iacopini, F.5    Iannoni, C.6
  • 23
    • 0029961595 scopus 로고    scopus 로고
    • Methotrexate and ulcerative colitis: Wrong drug?, wrong dose?, or wrong disease?
    • Kozarek R.A. Methotrexate and ulcerative colitis: Wrong drug?, wrong dose?, or wrong disease?. Gastroenterology 1996, 110:1652-1656.
    • (1996) Gastroenterology , vol.110 , pp. 1652-1656
    • Kozarek, R.A.1
  • 24
    • 0033406747 scopus 로고    scopus 로고
    • A randomized dose-response and pharmacokinetic study of methotrexate for refractory inflammatory Crohn's disease and ulcerative colitis
    • Egan L.J., Sandborn W.J., Tremaine W.J., Leighton J.A., Mays D.C., Pike M.G., et al. A randomized dose-response and pharmacokinetic study of methotrexate for refractory inflammatory Crohn's disease and ulcerative colitis. Aliment Pharmacol Ther 1999, 13(12):1597-1604.
    • (1999) Aliment Pharmacol Ther , vol.13 , Issue.12 , pp. 1597-1604
    • Egan, L.J.1    Sandborn, W.J.2    Tremaine, W.J.3    Leighton, J.A.4    Mays, D.C.5    Pike, M.G.6
  • 25
    • 38149057526 scopus 로고    scopus 로고
    • Comparison of the clinical efficacy and safety of subcutaneous versus oral administration of methotrexate in patients with active rheumatoid arthritis: results of a six-month, multicenter, randomized, double-blind, controlled, phase IV trial
    • Braun J., Kastner P., Flaxenberg P., Wahrisch J., Hanke P., Demary W., et al. Comparison of the clinical efficacy and safety of subcutaneous versus oral administration of methotrexate in patients with active rheumatoid arthritis: results of a six-month, multicenter, randomized, double-blind, controlled, phase IV trial. Arthritis Rheum 2008, 58(1):73-81.
    • (2008) Arthritis Rheum , vol.58 , Issue.1 , pp. 73-81
    • Braun, J.1    Kastner, P.2    Flaxenberg, P.3    Wahrisch, J.4    Hanke, P.5    Demary, W.6
  • 26
  • 27
    • 0030784425 scopus 로고    scopus 로고
    • Methotrexate in chronic active Crohn's disease: a double-blind, randomized, Israeli multicenter trial
    • Oren R., Moshkowitz M., Odes S., Becker S., Keter D., Pomeranz I., et al. Methotrexate in chronic active Crohn's disease: a double-blind, randomized, Israeli multicenter trial. Am J Gastroenterol 1997, 92(12):2203-2209.
    • (1997) Am J Gastroenterol , vol.92 , Issue.12 , pp. 2203-2209
    • Oren, R.1    Moshkowitz, M.2    Odes, S.3    Becker, S.4    Keter, D.5    Pomeranz, I.6
  • 28
    • 0009447497 scopus 로고    scopus 로고
    • Methotrexate in Crohn's disease: results of a randomized, double-blind, placebo-controlled trial
    • Arora S., Katkov W., Cooley J., Kemp J.A., Johnston D.E., Schapiro R.H., et al. Methotrexate in Crohn's disease: results of a randomized, double-blind, placebo-controlled trial. Hepatogastroenterology 1999, 46(27):1724-1729.
    • (1999) Hepatogastroenterology , vol.46 , Issue.27 , pp. 1724-1729
    • Arora, S.1    Katkov, W.2    Cooley, J.3    Kemp, J.A.4    Johnston, D.E.5    Schapiro, R.H.6
  • 29
    • 0036116379 scopus 로고    scopus 로고
    • The efficacy of methotrexate for maintaining remission in inflammatory bowel disease
    • Fraser A.G., Morton D., McGovern D., Travis S., Jewell D.P. The efficacy of methotrexate for maintaining remission in inflammatory bowel disease. Aliment Pharmacol Ther 2002, 16(4):693-697.
    • (2002) Aliment Pharmacol Ther , vol.16 , Issue.4 , pp. 693-697
    • Fraser, A.G.1    Morton, D.2    McGovern, D.3    Travis, S.4    Jewell, D.P.5
  • 30
    • 0037345575 scopus 로고    scopus 로고
    • Low dose methotrexate in inflammatory bowel disease: current status and future directions
    • Schroder O., Stein J. Low dose methotrexate in inflammatory bowel disease: current status and future directions. Am J Gastroenterol 2003, 98(3):530-537.
    • (2003) Am J Gastroenterol , vol.98 , Issue.3 , pp. 530-537
    • Schroder, O.1    Stein, J.2
  • 31
    • 0024457688 scopus 로고
    • 6-Mercaptopurine in the management of inflammatory bowel disease: short- and long-term toxicity
    • Present D.H., Meltzer S.J., Krumholz M.P., Wolke A., Korelitz B.I. 6-Mercaptopurine in the management of inflammatory bowel disease: short- and long-term toxicity. Ann Intern Med 1989, 111(8):641-649.
    • (1989) Ann Intern Med , vol.111 , Issue.8 , pp. 641-649
    • Present, D.H.1    Meltzer, S.J.2    Krumholz, M.P.3    Wolke, A.4    Korelitz, B.I.5
  • 32
    • 0028363515 scopus 로고
    • Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease
    • Connell W.R., Kamm M.A., Dickson M., Balkwill A.M., Ritchie J.K., Lennard-Jones J.E. Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease. Lancet 1994, 343(8908):1249-1252.
    • (1994) Lancet , vol.343 , Issue.8908 , pp. 1249-1252
    • Connell, W.R.1    Kamm, M.A.2    Dickson, M.3    Balkwill, A.M.4    Ritchie, J.K.5    Lennard-Jones, J.E.6
  • 33
    • 0033083008 scopus 로고    scopus 로고
    • Shingles during the course of treatment with 6-mercaptopurine for inflammatory bowel disease
    • Korelitz B.I., Fuller S.R., Warman J.I., Goldberg M.D. Shingles during the course of treatment with 6-mercaptopurine for inflammatory bowel disease. Am J Gastroenterol 1999, 94(2):424-426.
    • (1999) Am J Gastroenterol , vol.94 , Issue.2 , pp. 424-426
    • Korelitz, B.I.1    Fuller, S.R.2    Warman, J.I.3    Goldberg, M.D.4
  • 34
    • 0032754121 scopus 로고    scopus 로고
    • Malignant neoplasms subsequent to treatment of inflammatory bowel disease with 6-mercaptopurine
    • Korelitz B.I., Mirsky F.J., Fleisher M.R., Warman J.I., Wisch N., Gleim G.W. Malignant neoplasms subsequent to treatment of inflammatory bowel disease with 6-mercaptopurine. Am J Gastroenterol 1999, 94(11):3248-3253.
    • (1999) Am J Gastroenterol , vol.94 , Issue.11 , pp. 3248-3253
    • Korelitz, B.I.1    Mirsky, F.J.2    Fleisher, M.R.3    Warman, J.I.4    Wisch, N.5    Gleim, G.W.6
  • 35
    • 84921431104 scopus 로고    scopus 로고
    • Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis
    • Ortiz Z, Shea B, Suarez AM, Moher D, Wells G, Tugwell P. Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis. Cochrane Database Syst Rev 2000;(2):CD000951.
    • (2000) Cochrane Database Syst Rev , Issue.2
    • Ortiz, Z.1    Shea, B.2    Suarez, A.M.3    Moher, D.4    Wells, G.5    Tugwell, P.6


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