Efficacy and safety of azelaic acid (AzA) gel 15% in the treatment of post-inflammatory hyperpigmentation and acne: A 16-week, baseline-controlled study

Journal of Drugs in Dermatology

Volumn 10, Issue 6, 2011, Pages 586-590

  Kircik, Leon H ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZELAIC ACID;

ACNE; ADULT; ARTICLE; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ERYTHEMA; FEMALE; HUMAN; HYPERPIGMENTATION; MALE; POST INFLAMMATORY HYPERPIGMENTATION; SCORING SYSTEM; TREATMENT OUTCOME;

ACNE VULGARIS; ADMINISTRATION, CUTANEOUS; AFRICAN CONTINENTAL ANCESTRY GROUP; DERMATOLOGIC AGENTS; DICARBOXYLIC ACIDS; FEMALE; GELS; HUMANS; HYPERPIGMENTATION; INFLAMMATION; MALE; MONOPHENOL MONOOXYGENASE; PILOT PROJECTS; SEVERITY OF ILLNESS INDEX; SKIN PIGMENTATION; TREATMENT OUTCOME; YOUNG ADULT;

EID: 80053124725     PISSN: 15459616     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Callender VD. Acne in ethnic skin: Special considerations for therapy. Dermatol Ther. 2004;17(2):184-195. (Pubitemid 38656911)
2. Child FJ, Fuller LC, Higgins EM, Du Vivier AW. A study of the spectrum of skin disease occurring in a black population in southeast London. Br J Dermatol. 1999;141(3):512-517. (Pubitemid 29448414)
3. Kenney Ja Jr. Management of Dermatoses Peculiar to Negroes. Arch Dermatol. 1965;91:126-129.
4. Halder RM, Grimes PE, McLaurin CI, Kress MA, Kenney JA Jr. Incidence of common dermatoses in a predominantly black dermatologic practice. Cutis. 1983;32(4):388-390. (Pubitemid 13021298)
5. Taylor SC, Cook-Bolden F, Rahman Z, Strachan D. Acne vulgaris in skin of color. J Am Acad Dermatol. 2002;46(suppl 2):98S-106S.
6. Kligman AM, Shelley WB. An investigation of the biology of the human sebaceous gland. J Invest Dermatol. 1958;30(3):99-125.
7. Pochi PE, Strauss JS. Sebaceous gland activity in black skin. Dermatol Clin.1988;6(3):349-351.
8. Bulengo-Ransby SM, Griffiths CE, Kimbrough-Green CK, et al. Topical tretinoin (retinoic acid) therapy for hyperpigmented lesions caused by inflammation of the skin in black patients. N Engl J Med. 1993;20;328(20):1438- 1443.
9. Draelos Z, Kayne AL. Implications of azelaic acid's multiple mechanisms of action: Therapeutic versatility. Poster 443. Paper presented at: American Academy of Dermatology 66th Annual Meeting 2008; San Antonio, TX.
10. Passi S. Pharmacology and pharmacokinetics of azelaic acid. Rev Contemp Pharmacother. 1993;4:441-447.
11. Thiboutot D. Versatility of azelaic acid 15% gel in treatment of inflammatory acne vulgaris. J Drugs Dermatol. 2008;7(1):13-16.
12. Davis EC, Callender VD. A review of acne in ethnic skin: Pathogenesis, clinical manifestations, and management strategies. J Clin Aesthet Dermatol. 2010;3(4):24-38.
13. Grimes PE. Management of hyperpigmentation in darker racial ethnic groups. Semin Cutan Med Surg. 2009;28(2):77-85.