Different patterns of nigrostriatal degeneration in tremor type versus the akinetic-rigid and mixed types of Parkinson's disease at the early stages: Molecular imaging with 123I-FP-CIT SPECT

International Journal of Molecular Medicine

Volumn 28, Issue 5, 2011, Pages 881-886

  Schilaci, O ^a,b   Chiaravaloti, A ^a   Pierantozzi, M ^a,c   Di Pietro, B ^a   Koch, G ^a,c   Bruni, C ^a   Stanzione, P ^a,c   Stefani, A ^a,c  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b IRCCS NEUROMED   (Italy)

^c IRCCS FONDAZIONE SANTA LUCIA   (Italy)

Author keywords

Akineticrigid type; DAT SCAN; Mixed type; Parkinson's disease; Tremor type

Indexed keywords

IODINE 123;

ADULT; AKINESIA; ARTICLE; BRADYKINESIA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DOPAMINERGIC SYSTEM; FEMALE; HUMAN; MALE; MOLECULAR IMAGING; PARKINSON DISEASE; PATHOPHYSIOLOGY; PHENOTYPE; PHOTON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PUTAMEN; QUANTITATIVE ANALYSIS; RIGIDITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STRIATONIGRAL DEGENERATION; TREMOR;

FEMALE; HUMANS; MALE; MIDDLE AGED; PARKINSON DISEASE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TROPANES;

EID: 80053108289     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2011.764     Document Type: Article

References (33)

1. Marsden CA: Dopamine: the rewarding years. Br J Pharmacol 147: 136-144, 2006.
2. Gelb DJ, Oliver E and Gilman S: Diagnostic criteria for Parkinson disease. Arch Neurol 56: 33-39, 1999. (Pubitemid 29046907)
3. 18F-dopa uptake in Parkinson's disease, multiple system atrophy and progressive supranuclear palsy. Ann Neurol 28: 547-555, 1990.
4. Davis MR, Votaw JR, Bremner JD, et al: Initial human PET imaging studies with the dopamine transporter ligand 18F-FECNT. J Nucl Med 44: 855-861, 2003. (Pubitemid 39663394)
5. 123I-FP-CIT in progressive supranuclear palsy and in Parkinson's disease: a SPECT semi-quantitative study. Nucl Med Commun 27: 381-386, 2006.
6. Marek K, Jennings D and Seibyl J: Single-photon emission tomography and dopamine transporter imaging in Parkinson's disease. Adv Neurol 91: 183-191, 2003.
7. Ciliax BJ, Heilman C, Demchyshyn LL, et al: The dopamine transporter: immunochemical characterization and localization in brain. J Neurosci 15: 1714-1723, 1995.
8. Ahlskog JE: Diagnosis and differential diagnosis of Parkinson's disease and parkinsonism. Parkinsonism Relat Disord 7: 63-70, 2000.
9. Quinn N: Parkinsonism-recognition and differential diagnosis. BMJ 310: 447-452, 1995.
10. Rajput AH, Voll A, Rajputet ML, et al: Course in Parkinson disease subtypes: a 39-year clinicopathologic study. Neurology 73: 206-212, 2009.
11. Hughes A, Daniel SE, Kilford L and Lees AJ: Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 55: 181-184, 1992.
12. Fahn S, Elton RL and Members of the UPDRS Development Committee: Unified Parkinson's Disease rating scale. In: Recent Development in Parkinson's Disease. Vol. 2. Fahn S, Marsden CD, Calne DB and Goldstein M (eds). Macmillan Healthcare Information, Florhan Park, pp15 3-164, 1987.
13. Kang GA, Bronstein JM, Masterman DL, et al: Clinical characteristics in early Parkinson's disease in a central California population-based study. Mov Disord 20: 1133-1142, 2005. (Pubitemid 41632200)
14. Lewis SJ, Foltynie T, Blackwell AD, Robbins TW, Owen AM and Barker RA: Heterogeneity of Parkinson's disease in the early clinical stages using a data driven approach. J Neurol Neurosurg Psychiatry 76: 343-348, 2005. (Pubitemid 40299121)
15. Spiegel J, Hellwing D, Samnick S, Jost W, Mollers M, Fassbender K, Kirsch CM and Dillman U: Striatal FP-CIT uptake differs in the subtypes of early Parkinson's disease. J Neural Tansm 114: 331-335, 2007. (Pubitemid 46328648)
16. Tatsch K, Asenbaum S, Bartenstein P, et al: European Association of Nuclear Medicine procedure guidelines for brain neurotransmission SPET using 123I-labelled dopamine transporter ligands. Eur J Nucl Med Mol Imaging 29: 30-35, 2002.
17. Chang LT: A method for attenuation correction in radionuclide computed tomography. IEEE Trans Nucl Sci NS 25: 638-643, 1978.
18. 123I-FP-CIT SPET in the demonstration of the dopaminergic deficit in Parkinson's disease. Eur J Nucl Med 24: 68-71, 1997.
19. Schillaci O, Pierantozzi M, Filippi L, et al: The effect of levodopa therapy on dopamine transporter SPECT imaging with (123) I-FP-CIT in patients with Parkinson's disease. Eur J Nucl Med Mol Imaging 32: 1452-1456, 2005. (Pubitemid 41746850)
20. Bernheimer H, Birkmayer W, Hornykiewicz O, et al: Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations. J Neurol Sci 20: 415-455, 1973.
21. 123I)-FP-CIT study group. Mov Disord 15: 503-510, 2000.
22. Rajput AH, Sitte HH, Rajput A, et al: Globus pallidus dopamine and Parkinson motor subtypes: clinical and brain biochemical correlation. Neurology 70: 1403-1410, 2008. (Pubitemid 351521932)
23. Kägi G, Bhatia KP and Telosa E: The role of DAT-SPECT in movement disorders. J Neurol Neurosurg Psychiatry 81: 5-12, 2010.
24. 123I-FP-CIT striatal binding in early Parkinson's disease patients with tremor vs. akinetic-rigid onset. Neuroreport 18: 1499-1502, 2007.
25. Rossi C, Frosini D, Volterrani D, et al: Differences in nigro-striatal impairment in clinical variants of early Parkinson's disease: evidence from a FP-CIT SPECT study. Eur J Neurol 7: 626-630, 2010.
26. Jellinger KA: Post mortem studies on Parkinson's disease: is it possible to detect brain areas for specific symptoms? J Neural Transm Suppl 56: 1-29, 1999.
27. Carsten E, Deniz K, Gereon R, et al: Akinetic-rigid and tremor-dominant Parkinson's disease patients show different patterns of FP-CIT single photon emission computed tomography. Mov Disord 26: 416-423, 2011.
28. Varone A and Halldin C: Molecular imaging of the dopamine transporter. J Nucl Med 51: 1331-1334, 2010.
29. Pirker W: Correlation of dopamine transporter imaging with parkinsonian motor handicap: how close is it? Mov Disord 18: 43-51, 2003.
30. Selikhova M, Williams DR, Kempster PA, Holton JL, Revesz T and Lees AJ: A clinico-pathological study of subtypes in Parkinson's disease. Brain 132: 2947-2957, 2009.
31. Gordon PH, Pullman SL, Louis ED, et al: Mirtazapine in Parkinsonian tremor. Parkinsonism Relat Disord 9: 125-126, 2002. (Pubitemid 35447541)
32. Carr J: Tremor in Parkinson's disease. Parkinsonism Relat Disord 8: 223-234, 2002.
33. Rivlin-Etzion M, Marmor O, Heimer G, Raz A, Nini A and Bergman H: Basal ganglia oscillations and pathophysiology of movement disorders. Curr Opin Neurobiol 16: 629-637, 2006. (Pubitemid 44810892)