Polymorphisms in estrogen receptor-α are associated with idiopathic female infertility

Molecular Medicine Reports

Volumn 4, Issue 6, 2011, Pages 1239-1242

  Du, Jiu Wei ^a   Tao, Xin Rong ^a   Xu, Ke Yi ^a   Fang, Li Yi ^a   Qi, Xin Lan ^a  

^a ANHUI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Allelic variant; Dinucleotide repeat sequence; Estrogen receptor; Gene polymorphism; Infertility

Indexed keywords

DINUCLEOTIDE; ESTROGEN RECEPTOR ALPHA; RESTRICTION ENDONUCLEASE;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; ENZYME INHIBITION; FEMALE; FEMALE INFERTILITY; GENE AMPLIFICATION; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE; HUMAN; IDIOPATHIC DISEASE; MAJOR CLINICAL STUDY; PREDICTIVE VALUE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR;

ADULT; ALLELES; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; INFERTILITY, FEMALE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RISK FACTORS;

EID: 80053093649     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2011.551     Document Type: Article

References (15)

1. Spira A: Epidemiology of human reproduction. Hum Reprod 1: 111-115, 1986.
2. Haller K, Salumets A, Grigorova M, et al: Putative predictors of antibodies against follicle-stimulating hormone in female infertility: a study based on in vitro fertilization patients. Am J Reprod Immunol 57: 193-200, 2007. (Pubitemid 46237384)
3. Figtree GA, Noonan JE, Bhindi R and Collins P: Estrogen receptor polymorphisms: significance to human physiology, disease and therapy. Recent Pat DNA Gene Seq 3: 164-171, 2009.
4. Nilsson M, Naessen S, Dahlman I, Linden Hirschberg A, Gustafsson JA and Dahlman-Wright K: Association of estrogen receptor β gene polymorphisms with bulimic disease in women. Mol Psychiatry 9: 28-34, 2004. (Pubitemid 38175079)
5. Ivanova JT, Doukova PB, Boyanov MA and Popivanov PR: PvuII and XbaI polymorphisms of the estrogen receptor gene and bone mineral density in a Bulgarian population sample. Hormones (Athens) 6: 36-43, 2007.
6. Molvarec A, Nagy B, Kovacs M, et al: Lipid, haemostatic and inflammatory variables in relation to the estrogen receptor α (ESR1) PvuII and XbaI gene polymorphisms. Clin Chim Acta 380: 157-164, 2007. (Pubitemid 46498052)
7. Sundermann EE, Maki PM and Bishop JR: A review of estrogen receptor α gene (ESR1) polymorphisms, mood, and cognition. Menopause 17: 874-886, 2010.
8. Langdahl BL, Lokke E, Carstens M, Stenkjaer LL and Eriksen EF: A TA repeat polymorphism in the estrogen receptor gene is associated with osteoporotic fractures but polymorphisms in the first exon and intron are not. J Bone Miner Res 15: 2222-2230, 2000.
9. Ayvaz OU, Ekmekci A, Baltaci V, Onen HI and Unsal E: Evaluation of in vitro fertilization parameters and estrogen receptor α gene polymorphisms for women with unexplained infertility. J Assist Reprod Genet 26: 503-510, 2009.
10. Corbo RM, Gambina G, Ruggeri M and Scacchi R: Association of estrogen receptor α (ESR1) PvuII and XbaI polymorphisms with sporadic Alzheimer's disease and their effect on apolipoprotein E concentrations. Dement Geriatr Cogn Disord 22: 67-72, 2006.
11. Sato H, Nogueira-de-Souza NC, D'Amora P, Silva ID, Girao MJ and Schor E: Intron 1 and exon 1 α estrogen receptor gene polymorphisms in women with endometriosis. Fertil Steril 90: 2086-2090, 2008.
12. Georgopoulos NA, Adonakis GL, Fotopoulos A, et al: Estrogen receptor polymorphisms in tamoxifen-treated women with breast cancer. Gynecol Endocrinol 22: 185-189, 2006.
13. Gennari L, Merlotti D, De Paola V, et al: Estrogen receptor gene polymorphisms and the genetics of osteoporosis: a HuGE review. Am J Epidemiol 161: 307-320, 2005. (Pubitemid 40256202)
14. Gupta L, Thakur H, Sobti RC, Seth A and Singh SK: Role of genetic polymorphism of estrogen receptor-α gene and risk of prostate cancer in north Indian population. Mol Cell Biochem 335: 255-261, 2010.
15. Kim SH, Choi YM, Jun JK, Kim JG and Moon SY: Estrogen receptor dinucleotide repeat polymorphism is associated with minimal or mild endometriosis. Fertil Steril 84: 774-777, 2005.