Phytochemical and pharmacological evaluation of Capparis decidua (Forsk.) Edgew stem for central nervous system depressant activity

Pharmacologyonline

Volumn 2, Issue , 2011, Pages 146-155

  Garg, Preeti ^a   Sachdeva, Kamal ^b   Bhandari, Isha ^c  

^a SURESH GYAN VIHAR UNIVERSITY   (India)

^b JAIPUR NATIONAL UNIVERSITY   (India)

^c Rajendra college of pharmacy ^*  (India)

Author keywords

Antianxiety; Capparis decidua; Locomotor; Muscle relaxant

Indexed keywords

ANXIOLYTIC AGENT; CAPPARIS DECIDUA EXTRACT; CENTRAL DEPRESSANT AGENT; DIAZEPAM; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; BIOCHEMICAL COMPOSITION; CAPARIS DECIDUA; CAPPARACEAE; CENTRAL NERVOUS SYSTEM DEPRESSION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; FEMALE; LIGHT DARK CYCLE; LOCOMOTION; MALE; MAZE TEST; MOUSE; MUSCLE FUNCTION; MUSCLE RELAXATION; NERVOUS SYSTEM PARAMETERS; NONHUMAN; OPEN FIELD BEHAVIOR; OPEN FIELD TEST; PHOTOMETER; PHYTOCHEMISTRY; PLANT STEM; ROTAROD TEST; TASK PERFORMANCE; TOXICITY TESTING; TRANQUILIZING ACTIVITY;

EID: 80053085970     PISSN: None     EISSN: 18278620     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Dhawan K. Dhavan S, Chhabra S, et al. Attenuation of benzodiazepine dependence in mice by a trisubstituted benzoflavone moiety of Passiflora incarnata Linneous: A non habit forming anxiolytic. J Pharm Pharmceu Sci 2003; 6(2): 215-222.
2. Evan WC. Trease and Evans Pharmacognosy, 14th ed. India, Harcourt Brace and Company, 1998.
3. http://en.wikipedia.org/wiki/Capparis accessed on 20th Jan, 2009.
4. The Wealth of India, "Raw material", rep.1992, New Delhi, publications and information directorate, 211; 3.
5. Baumer M. Notes on trees and shrubs in arid and semi-arid regions. Rome FAO Forestry Division, 1983.
6. Ahmad VU. Isamil N, Arif S, Amber AR, et al. Two new N-acetylated spermidine alkaloids from Capparis decidua. J Nat Prod 1992; 55: 1509-1512.
7. Gaind KN. Juneja TR, et al. Capparis decidua phytochemical study of flowers and fruits. Res Bull Punjab Uni Sci 1970; 21: 67-71.
8. Ali SA. Al-Amin TH, Mohamed AH, Gameel AA, et al. Hepatoprotective activity of aqueous and methanolic extracts of Capparis decidua stems against carbon tetrachloride induced liver damage in rats. J Pharmaco Toxicol 2009; 4: 167-172.
9. Rathee S. Mogla OP, Sardana S, Vats M, Rathee P, et al. Antidiabetic activity of Capparis decidua Forsk Edgew. J Pharm Research 2010; 3.
10. Goyal M. Nagori BP, Sasmal D, et al. Sedative and anti-convulsant effects of an alcoholic extract of Capparis decidua. J Nat Med 2008; 63: 375-379.
11. Purohit A. Vyas KB, et al. Antiatherosclerotic effect of Capparis decidua fruit extract in cholesterol-fed rabbits. Pharmaceutical Biol 2006; 44: 172-177.
12. Navanth MS. Naikwade NS, Mule SN, et al. Analgesic, Anti-Inflammatory and CNS Depressant Activity of Capparis decidua Edgew Flowers. J Pharm Research 2009; 2: 1307-1310.
13. Harborne JB. Phytochemical methods-a guide to modern techniques of plant analysis, 2nd ed. New York, Chapman and Hall, 1984.
14. Khandelwal KR. Practical Pharmacognosy technique and experiments, 9th ed. Pune, Nirali Prakashan, 2002: 149-156.
15. Wagner H. Bladt S, Zgainski EM, et al. Plant drug analysis-a thin layer chromatography atlas. Springer-Verlag Berlin + Heiderberg, New York 1984.
16. William K. Organic spectroscopy. 3rd ed. Macmillan Press Ltd., London 1991.
17. Health effects test guidelines. Acute oral toxicity (computer program) OPPTS 870-1100 United States office of prevention agency (7101). Available from: URL http://www. epa. gov/ opts/ home/ guideline. htm.
18. Lalitha KG. Sathish R, Gayathri R, Karthikeyan S, Kalaiselvi P, Muthuboopathi G, et al. Pharmacological Evaluation of Clerodendrum Philippinum Schauer Flowers for Antianxiety and Central Nervous System Depressant Activity. International Journal of Pharmaceutical Research 2010; 2(2): 445-467.
19. Allmark MG. Bachinski WM, et al. A method of assay for curare using rats. J Am Ph Ass 1949; 38: 43-45.
20. Vogel GH. Wolfgang H, et al. Drug Discovery and Evaluation. Verlag+ Springer 1997.
21. Hogg SA, Review of the validity and Variability of the elevated plus-maze as an animal model of anxiety. Pharmacol Biochem Behav 1996; 54: 21-30.
22. Pellow S. File SE, et al. Anxiolytic and axiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat. Pharmacol Biochem Behav 1986; 24: 525-29.
23. Kulkarni SK. Handbook of experimental pharmacology, 3rd ed. New Delhi, Vallabh Prakashan, 2007: 43-45.
24. Deborah A. Gries GA, Condouris SZ, Houpt M, et al. Anxiolytic-like action in mice treated with nitrous oxide and oral triazolam or diazepam. Life Sci 2005; 76: 1667-1674.
25. Nishikava H. Hata T, Funakami Y, et al. A role for corticotropin-releasing factor in repeated cold stress-induced anxiety-like behavior during forcedswimming and elevated plus-maze testin mice. Biol Pharm Bull 2004; 27(3): 352-356.
26. Millan MJ. Veiga S, Goument B, et al. S15535, A novel benzodioxopiperazine ligand of serotonin (%-5HT) 1A receptor: II. Modulation of hippocampal sertonin release in relation to potential anxiolytic properties. J Pharmacol Exp Ther 1997; 282: 148-161.