A new body moisturizer increases skin hydration and improves atopic dermatitis symptoms among children and adults

Journal of Drugs in Dermatology

Volumn 10, Issue 7, 2011, Pages 744-749

  Simpson, Eric ^a   Dutronc, Yves ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b Galderma R and D   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CETAPHIL RESTORADERM; CORTICOSTEROID; DERMATOLOGICAL AGENT; DODECYL SULFATE SODIUM; MOISTURIZING AGENT; UNCLASSIFIED DRUG;

ABSENCE OF SIDE EFFECTS; ADOLESCENT; ADULT; ARTICLE; ATOPIC DERMATITIS; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG TOLERABILITY; FEMALE; HUMAN; HYDRATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PATIENT SATISFACTION; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE;

ADOLESCENT; ADULT; AGED; ANTIPRURITICS; CHILD; CHILD, PRESCHOOL; CLINICAL TRIALS AS TOPIC; DERMATITIS, ATOPIC; EMOLLIENTS; FEMALE; HUMANS; MIDDLE AGED; PRURITUS; SKIN; YOUNG ADULT;

EID: 80053083069     PISSN: 15459616     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Darsow U, Wollenberg A, Simon D, et al. ETFAD:EADV eczema task force 2009 positiion paper on diagnosis and treatment of atopic dermatitis. J Eur Acad Dermatol Venerol. 2010;24:317-328.
2. Imokawa G, Abe A, Jin K et al. Decreased level of ceramides in stratum corneum of atopic dermatitis: An etiologic factor in atopic dry skin? J Invest Dermatol. 1991;96:523-526.
3. Yamamotot A, Serizawa S, Ito M, Sato Y. Stratum corneum lipid abnormalities in atopic dermatitis. Arch Dermatol Res. 1991;283: 219-223.
4. Palmer CAN, Irvine AD, Terron-Kwiatkowski A, et al. Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat Genet. 2006;38:441-446
5. Simpson EL. Atopic dermatitis: A review of topical treatment options. Curr Med Res Opion. 2010;26:633-640.
6. Hanifin JM, Cooper KD, Ho VC, et al. Guidelines of care for atopic dermatitis, developed in accordance with the American Academy of Dermatology (AAD)/American Academy of Dermatology Association "administrative regulations for evidence-based clinical practice guidelines". J Am Acad Dermatol. 2004;50:391-404.
7. Ellis C, Luger T, Abeck D, et al. International consensus conference on atopic dermatitis II (ICCAD II): Clinical update and current treatment strategies. Br J Dermatol. 2003;148(supp):3-10.
8. Laquieze S, Czernielewski J, Rueda M-J. Beneficial effect of a moisturizing cream as adjunctive treatment to oral isotretinoin or topical tretinoin in the management of acne. J Drugs Dermatol. 2006;5(10):985-990.
9. Laquieze S, Czernielewski J, Baltas E. Beneficial use of Cetaphil moisturizing cream as part of a daily skin care regimen for individuals with rosacea. J Drugs Dermatol. 2007;18:985-890.
10. Pinnagoda J, Tupker RA, Agner T, Serup J. Guidelines for transepidermal water loss (TEWL) measurement. Contact Dermatitis. 1990;22:164-178.
11. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol (Stockh). 1980;92(suppl):44-7.
12. Hanifin JM, Thurston M, Omoto M, et al. The eczema area and severity index (EASI): Assessment of reliability in atopic dermatitis. EASI Evaluator Group. Exp Dermatol. 2001;10:11-18. (Pubitemid 32098039)
13. Barbier N, Paul C, Luger T, et al. Validation of the Eczema Area and Severity Index for atopic dermatitis in a cohort of 1550 patients from the pimecrolimus cream 1% randomized controlled clinical trials programme. Br J Dermatol. 2004;150:96-102. (Pubitemid 38234012)
14. Krejci-Manwaring J, Tusa MG, Caroll C, et al. Stealth monitoring of adherence to topical medication: Adherence is very poor in children with atopic dermatitis. J Am Acad Dermatol. 2007;56:2116.
15. Brown KL, Krejci-Manwaring J, Tusa MG, et al. Poor compliance with topical corticosteroids for atopic dermatitis despite severe disease. Dermatol Online J. 2008;14:13.
16. Szczepanowska J, Eich A, Szepietowski JC. Emollients improve treatment results with topical corticosteroids in childhood atopic dermatitis: a randomized comparative study. Pediatr Allergy Immunol. 2008;19:614-618.
17. Simpson EL, Berry TM, Brown PA, Hanifin JM. A pilot study of emollient therapy for the primary prevention of atopic dermatitis. J Am Acad Dermatol. 2010;63:587-93.
18. Charman C, Williams H. The use of corticosteroids and corticosteroid phobia in atopic dermatitis. Clin Dermatol. 2003;21:193-200. (Pubitemid 36629331)
19. Msika P, De Belilovsky C, Piccardi N, et al. New emollient with topical corticosteroid-sparing effect in treatment of childhood atopic dermatitis: SCORAD and quality of life improvement. Pediatr Dermatol. 2008;25(6):606-612.